N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma

Experimental Neurology

Volumn 257, Issue , 2014, Pages 95-105

  Patel, Samir P ^a   Sullivan, Patrick G ^a   Pandya, Jignesh D ^a   Goldstein, Glenn A ^b   VanRooyen, Jenna L ^a   Yonutas, Heather M ^a   Eldahan, Khalid C ^a   Morehouse, Johnny ^c   Magnuson, David S K ^c   Rabchevsky, Alexander G ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c University of Louisville School of Medicine   (United States)

Author keywords

Contusion spinal cord injury; Gait analysis; N acetylcysteine amide (NACA); Neuroprotective agent; Therapeutics

Indexed keywords

CYTOCHROME C OXIDASE; GLUTATHIONE; N ACETYLCYSTEINE AMIDE; NEUROPROTECTIVE AGENT; PYRUVATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENERGY RECOVERY; ENZYME ACTIVITY; FEMALE; FUNCTIONAL ASSESSMENT; FUNCTIONAL STATUS; LOCOMOTION; LUMBAR SPINAL CORD; MITOCHONDRIAL BIOENERGETICS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY;

CONTUSION SPINAL CORD INJURY; GAIT ANALYSIS; N-ACETYLCYSTEINE AMIDE (NACA); NEUROPROTECTIVE AGENT; THERAPEUTICS;

ACETYLCYSTEINE; ANIMALS; DISEASE MODELS, ANIMAL; DOUBLE-BLIND METHOD; DRUG DELIVERY SYSTEMS; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ENERGY METABOLISM; FEMALE; GANGLIA, SPINAL; LAMENESS, ANIMAL; MITOCHONDRIA; MOTOR ACTIVITY; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SPINAL CORD; SPINAL CORD INJURIES; SYNAPSES; TIME FACTORS;

EID: 84900858343     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.04.026     Document Type: Article

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