Adjunct minocycline to clozapine treated patients with persistent schizophrenia symptoms

Schizophrenia Research

Volumn 133, Issue 1-3, 2011, Pages 257-258

  Kelly, Deanna L ^a   Vyas, Gopal ^b   Richardson, Charles M ^b   Koola, Maju ^a   McMahon, Robert P ^a   Buchanan, Robert W ^a   Wehring, Heidi J ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Spring Grove Hospital Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE; CLOZAPINE; LAMOTRIGINE; LITHIUM; MINOCYCLINE; OLANZAPINE; RISPERIDONE; TOPIRAMATE;

ABDOMINAL PAIN; ABSENCE OF SIDE EFFECTS; ADULT; AFFECTIVE BLUNTING; ANXIETY; AUDITORY HALLUCINATION; CALGARY DEPRESSION SCALE; CASE REPORT; CATATONIC SCHIZOPHRENIA; CONSTIPATION; DELUSION; DEPRESSION; DISEASE SEVERITY; DISTRESS SYNDROME; DRUG BLOOD LEVEL; DRUG DOSE TITRATION; DRUG RESPONSE; EMOTIONAL DISORDER; EYE; EYE CONTACT; HUMAN; INDEPENDENCE; LETTER; MALE; NAUSEA; NEGATIVE SYNDROME; PERSECUTORY DELUSION; POSITIVE SYNDROME; PRIORITY JOURNAL; SCORING SYSTEM; SELF CARE; SOCIAL INTERACTION; SOMATIC DELUSION; SPEECH DISORDER; SYMPTOM; THINKING; THOUGHT DISORDER; VISUAL HALLUCINATION; VOICE; VOICE AUDIBILITY;

ADULT; ANTIPSYCHOTIC AGENTS; CLOZAPINE; HUMANS; MALE; MINOCYCLINE; SCHIZOPHRENIA;

EID: 81955168013     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2011.08.005     Document Type: Letter

References (13)

1. Chaves C., Marque C.R., Trzesniak C., Machado De Sousa J.P., Zuardi A.W., Crippa J.A., Dursun S.M., Hallak J.E. Glutamate-N-methyl-D-aspartate receptor modulation and minocycline for the treatment of patients with schizophrenia: an update. Braz. J. Med. Biol. Res. 2009, 42(11):1002-1014.
2. Chaves C., De Marque C.R., Wichert-Ana L., Maia-De-Oliveira J.P., Itikawa E.N., Crippa J.A., Zuardi A.W., Todd K.G., Baker G.B., Dursun S.M., Hallak J.E. Functional neuroimaging of minocycline's effect in a patient with schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2010, 34(3):550-552.
3. Fujita Y., Ishima T., Kunitachi S., Hagiwara H., Zhang L., Iyo M., Hashimoto K. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antibiotic drug minocycline. Prog. Neuropsychopharmacol. Biol. Psychiatry 2008, 32(2):336-339.
4. Goff D.C. Review: lamotrigine may be an effective treatment for clozapine resistant schizophrenia. Evid. Based Ment. Health 2009, 12(4):111.
5. Lee C.Y., Fu W.M., Chen C.C., Su M.J., Liou H.H. Lamotrigine inhibits postsynaptic AMPA receptor and glutamate release in the dentate gyrus. Epilepsia 2008, 49(5):888-897.
6. Levkovitz Y., Mendlovich S., Riwkes S., Braw Y., Levkovitch-Verbin H., Gal G., Fennig S., Treves I., Kron S. A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia. J. Clin. Psychiatry 2010, 71(2):138-149.
7. Manev R., Manev H. Minocycline, schizophrenia and GluR1 glutamate receptors. Prog. Neuropsychopharmacol. Biol. Psychiatry 2009, 33(1):166. author reply 167.
8. Miyaoka T., Yasukawa R., Yasuda H., Hayashida M., Inagaki T., Horiguchi J. Possible antipsychotic effects of minocycline in patients with schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2007, 31(1):304-307.
9. Miyaoka T., Yasukawa R., Yasuda H., Hayashida M., Inagaki T., Horiguchi J. Minocycline as adjunctive therapy for schizophrenia: an open-label study. Clin. Neuropharmacol. 2008, 31(5):287-292.
10. Sommer I.E., Begemann M.J., Temmerman A., Leucht S. Pharmacological augmentation strategies for schizophrenia patients with insufficient response to clozapine: a quantitative literature review. Schizophr. Bull. 2011, (2010 Electronic publication ahead of print).
11. Tiihonen J., Wahlbeck K., Kiviniemi V. The efficacy of lamotrigine in clozapine-resistant schizophrenia: a systematic review and meta-analysis. Schizophr. Res. 2009, 109(1-3):10-14.
12. Zhang L., Shirayama Y., Iyo M., Hashimoto K. Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine. Neuropsychopharmacology 2007, 32(9):2004-2010.
13. Zoccali R., Muscatello M.R., Bruno A., Cambria R., Mico U., Spina E., Meduri M. The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: a double-blind, placebo-controlled study. Schizophr. Res. 2007, 93(1-3):109-116.