Elements and modulation of functional dynamics

Journal of Medicinal Chemistry

Volumn 57, Issue 19, 2014, Pages 7819-7837

  Gibbs, Alan C ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELEMENT; ESTROGEN RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN G; PROTEIN;

ALLOSTERISM; ARTICLE; CATALYSIS; CONFORMATIONAL ENSEMBLE; CONFORMATIONAL TRANSITION; DRUG RESISTANCE; ENERGY TRANSFER; ENTHALPY; ENTROPY; HIGH THROUGHPUT SCREENING; HUMAN; LIGAND BINDING; MACROMOLECULE; MODULATION; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY; CHEMISTRY; DRUG DESIGN; MUTATION; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

DRUG DESIGN; DRUG RESISTANCE; ENTROPY; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN CONFORMATION; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 84907919370     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm500325k     Document Type: Article

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