Increased backbone mobility in β-barrel enhances entropy gain driving binding of N-TIMP-1 to MMP-3

Journal of Molecular Biology

Volumn 327, Issue 3, 2003, Pages 719-734

  Arumugam, S ^a,c   Gao, Guanghua ^a,d   Patton, Brian L ^a   Semenchenko, Valentyna ^a   Brew, Keith ^b   Van Doren, Steven R ^a  

^a University of Missouri   (United States)

^b FLORIDA ATLANTIC UNIVERSITY   (United States)

^c UNIVERSITY OF LOUISVILLE   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Backbone dynamics; Protein protein interactions; Residual dipolar couplings; Structure based thermodynamics

Indexed keywords

STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ARTICLE; BETA SHEET; BINDING AFFINITY; BINDING KINETICS; CALORIMETRY; CONFORMATIONAL TRANSITION; ENTROPY; HEAT; HYDROPHOBICITY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; THERMODYNAMICS; TITRIMETRY; X RAY ANALYSIS;

EID: 0037470616     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00180-3     Document Type: Article

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