Identification of pathway-selective estrogen receptor ligands that inhibit NF-κB transcriptional activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 7, 2005, Pages 2543-2548

  Chadwick, Christopher C ^a,b   Chippari, Susan ^a   Matelan, Edward ^a   Borges Marcucci, Lisa ^a   Eckert, Amy M ^a   Keith Jr , James C ^a   Albert, Leo M ^a   Leathurby, Yelena ^a   Harris, Heather A ^a   Bhat, Ramesh A ^a   Ashwell, Mark ^a   Trybulski, Eugene ^a,c   Winneker, Richard C ^a   Adelman, Steven J ^a   Steffan, Robert J ^a   Harnish, Douglas C ^a  

^a PFIZER INC   (United States)

^b Life Diagnostics Inc   (United States)

^c ARQULE INC   (United States)

Author keywords

Inflammation; Therapy

Indexed keywords

ESTROGEN RECEPTOR; FULVESTRANT; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; UNCLASSIFIED DRUG; WAY 169916;

AORTA; ARTICLE; ATHEROSCLEROSIS; CHRONIC INFLAMMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENTERITIS; ESTROGEN ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; OVARIECTOMY; POLYADENYLATION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; TRANSCRIPTION REGULATION; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL LINE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HLA-B27 ANTIGEN; HUMANS; INFLAMMATORY BOWEL DISEASES; LIGANDS; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; PYRAZOLES; RATS; RECEPTORS, ESTROGEN; TRANSCRIPTION, GENETIC; UTERUS;

ANIMALIA;

EID: 20044371621     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0405841102     Document Type: Article

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