Ligand Clouds around Protein Clouds: A Scenario of Ligand Binding with Intrinsically Disordered Proteins

PLoS Computational Biology

Volumn 9, Issue 10, 2013, Pages

  Jin, Fan ^a,b   Yu, Chen ^a   Lai, Luhua ^a,b   Liu, Zhirong ^a,b  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; DIAGNOSIS; HYDROGEN BONDS; MOLECULES; PEPTIDES;

DRUG DESIGN; EXTENSIVE SIMULATIONS; HUMAN DISEASE; INTRINSICALLY DISORDERED PROTEINS; LIGAND BINDING; MOLECULE LIGANDS; POTENTIAL DRUG; SMALL MOLECULES; SMALL-MOLECULE INHIBITORS; STRUCTURAL DISORDERS;

LIGANDS;

LIGAND; MYC PROTEIN; ONCOPROTEIN;

ARTICLE; BINDING SITE; DRUG DESIGN; DRUG TARGETING; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; SIMULATION;

COMPUTATIONAL BIOLOGY; DRUG DESIGN; INTRINSICALLY DISORDERED PROTEINS; LIGANDS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-MYC; THERMODYNAMICS;

EID: 84887305278     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003249     Document Type: Article

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