Communication Breakdown: Protein Dynamics and Drug Design

Structure

Volumn 17, Issue 3, 2009, Pages 319-320

  Peng, Jeffrey W ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; HOLOENZYME; PROTEIN;

BINDING SITE; CORRELATION ANALYSIS; DRUG BINDING; DRUG DESIGN; DRUG INDUSTRY; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION;

BINDING SITES; DRUG DESIGN; FOLIC ACID ANTAGONISTS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 61449163022     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2009.02.004     Document Type: Short Survey

References (12)

1. Boehr D.D., McElheny D., Dyson H.J., and Wright P.E. Science 313 (2006) 1638-1642
2. Cheng J.W., Lepre C.A., and Moore J.M. Biochemistry 33 (1994) 4093-4100
3. Clarkson M.W., Gilmore S.A., Edgell M.H., and Lee A.L. Biochemistry 45 (2006) 7693-7699
4. Eisenmesser E.Z., Bosco D.A., Akke M., and Kern D. Science 295 (2002) 1520-1523
5. Fuentes E.J., Der C.J., and Lee A.L. J. Mol. Biol. 335 (2004) 1105-1115
6. Hammes-Schiffer S., and Benkovic S.J. Ann. Rev. Biochem. 75 (2006) 519-541
7. Mauldin R.V., Carroll M.J., and Lee A.L. Structure 17 (2009) 386-394 this issue
8. Namanja A.T., Peng T., Zintsmaster J.S., Elson A.C., Shakour M.G., and Peng J.W. Structure 15 (2007) 313-327
9. Nicholson L.K., Yamazaki T., Torchia D.A., Grzesiek S., Bax A., Stahl S.J., Kaufman J.D., Wingfield P.T., Lam P.Y., Jadhav P.K., et al. Nat. Struct. Biol. 2 (1995) 274-280
10. Palmer III A.G. Chem. Rev. 104 (2004) 3623-3640
11. Peng J.W. J. Am. Chem. Soc. 125 (2003) 11116-11130
12. Zintsmaster J.S., Wilson B.D., and Peng J.W. J. Am. Chem. Soc. 130 (2008) 14060-14061