Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor

Nature Chemical Biology

Volumn 10, Issue 1, 2014, Pages 18-20

  Bock, Andreas ^a,b   Chirinda, Brian ^a   Krebs, Fabian ^a   Messerer, Regina ^b   Bätz, Julia ^c   Muth, Mathias ^b   Dallanoce, Clelia ^d   Klingenthal, Dominika ^a   Tränkle, Christian ^a   Hoffmann, Carsten ^c   De Amici, Marco ^d   Holzgrabe, Ulrike ^b   Kostenis, Evi ^a   Mohr, Klaus ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LIGAND; MUSCARINIC M2 RECEPTOR;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL POPULATION; FEMALE; LIGAND BINDING; NONHUMAN; PARTIAL AGONISM; POPULATION DYNAMICS; PRIORITY JOURNAL; PROTEIN FUNCTION;

BINDING SITES; LIGANDS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84890966535     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1384     Document Type: Article

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