Evidence for dynamics in proteins as a mechanism for ligand dissociation

Nature Chemical Biology

Volumn 8, Issue 3, 2012, Pages 246-252

  Carroll, Mary J ^a   Mauldin, Randall V ^b   Gromova, Anna V ^a   Singleton, Scott F ^a   Collins, Edward J ^b   Lee, Andrew L ^a,b  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINOPYRIMIDINE INHIBITOR; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR; LIGAND; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATION; DISPERSION; DYNAMICS; LIGAND BINDING; LIGAND DISSOCIATION; MACROMOLECULE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

EID: 84857190619     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.769     Document Type: Article

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