Insights into internal dynamics of 6-phosphogluconolactonase from Trypanosoma brucei studied by nuclear magnetic resonance and molecular dynamics

Proteins: Structure, Function and Bioinformatics

Volumn 80, Issue 4, 2012, Pages 1196-1210

  Calligari, Paolo A ^a,b,c   Salgado, Gilmar F ^a,b,c   Pelupessy, Philippe ^a,b,c   Lopes, Philippe ^d   Ouazzani, Jamal ^d   Bodenhausen, Geoffrey ^a,b,c,e   Abergel, Daniel ^a,b,c  

^a ECOLE NORMALE SUPÉRIEURE   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c CNRS   (France)

^d INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^e EPFL   (Switzerland)

Author keywords

6 phospho gluconolactonase (6PGL); Molecular dynamics simulations (MD); NMR; Protein dynamics; Relaxation

Indexed keywords

6 PHOSPHOGLUCONOLACTONASE; GLOBULAR PROTEIN; GLUCONOLACTONASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; ENZYME ACTIVITY; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; TRYPANOSOMA BRUCEI;

BINDING SITES; CARBOXYLIC ESTER HYDROLASES; COMPUTATIONAL BIOLOGY; GLUCONATES; HOLOENZYMES; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS SIMULATION; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; PROTOZOAN PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA BRUCEI BRUCEI;

TRYPANOSOMA BRUCEI;

EID: 84857787795     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24019     Document Type: Article

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