Role of pregnane X receptor in chemotherapeutic treatment

Cancer Chemotherapy and Pharmacology

Volumn 74, Issue 2, 2014, Pages 217-227

  Zhuo, Wei ^a,b,c   Hu, Lei ^a,b,c   Lv, Jinfeng ^a,b,c   Wang, Hongbing ^d   Zhou, Honghao ^a,b,c   Fan, Lan ^a,b,c  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c Hunan Key Laboratory of Pharmacogenetics   (China)

^d UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

Chemotherapeutic drugs; Metabolism; Pharmacogenomics; PXR

Indexed keywords

CYTOCHROME P450 3A; DOXORUBICIN; IRINOTECAN; PACLITAXEL; PREGNANE X RECEPTOR; TAMOXIFEN; VINBLASTINE;

CANCER CHEMOTHERAPY; CELL PROLIFERATION; DNA BINDING; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG EFFICACY; DRUG METABOLISM; ETHNIC GROUP; GENE FUNCTION; GENETIC VARIABILITY; HUMAN; NONHUMAN; PHARMACOGENOMICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; REVIEW; TUMOR GROWTH; UPREGULATION; XENOBIOTIC METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS; HUMANS; NEOPLASMS; RECEPTORS, STEROID;

EID: 84907598961     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-014-2494-9     Document Type: Review

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