-
1
-
-
13144260727
-
Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction
-
USA
-
ertilsson, G., Heidrich, J., Svensson, K., Asman, M., Jendeberg, L., Sydow-Backman, M., Ohlsson, R., Postlind, H., Blomquist, P.and Berkenstam, A.: Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc. Natl. Acad.ci. USA, 95: 12208-12213 (1998).
-
(1998)
Proc. Natl. Acad.ci.
, vol.95
, pp. 12208-12213
-
-
ertilsson, G.1
Heidrich, J.2
Svensson, K.3
Asman, M.4
Jendeberg, L.5
Sydow-Backman, M.6
Ohlsson, R.7
Postlind, H.8
Blomquist, P.9
Berkenstam, A.10
-
2
-
-
0032169485
-
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
-
Lehmann, J. M., McKee, D. D., Watson, M. A., Willson, T. M., Moore, J. T. and Kliewer S. A.: The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J. Clin. Invest., 102: 1016-1023 (1998).
-
(1998)
J. Clin. Invest
, vol.102
, pp. 1016-1023
-
-
Lehmann, J.M.1
McKee, D.D.2
Watson, M.A.3
Willson, T.M.4
Moore, J.T.5
Kliewer, S.A.6
-
3
-
-
0032532134
-
SXR, a novel steroid and xenobiotic-sensing nuclear receptor
-
Blumberg, B., Sabbagh, W. Jr., Juguilon, H., Bolado, J. Jr., van Meter, C. M., Ong, E. S. and Evans, R. M.: SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev., 12: 3195-3205 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 3195-3205
-
-
Blumberg, B.1
Sabbagh, W.2
Juguilon, H.3
Bolado, J.4
van Meter, C.M.5
Ong, E.S.6
Evans, R.M.7
-
4
-
-
0036171965
-
Regulation of CYP3A gene transcription by the pregnane X receptor.
-
Goodwin, B., Redinbo, M. R. and Kliewer, S. A.: Regulation of CYP3A gene transcription by the pregnane X receptor. Annu. Rev. Pharmacol. Toxicol., 42, 1-23 (2002).
-
(2002)
Annu. Rev. Pharmacol. Toxicol.
, vol.42
, pp. 1-23
-
-
Goodwin, B.1
Redinbo, M.R.2
Kliewer, S.A.3
-
5
-
-
0036515846
-
Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man
-
Gibson, G. G., Plant, N. J., Swales, K. E., Ayrton, A. and El-Sankary, W.: Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man. Xenobiotica, 32: 165-206 (2002).
-
(2002)
Xenobiotica
, vol.32
, pp. 165-206
-
-
Gibson, G.G.1
Plant, N.J.2
Swales, K.E.3
Ayrton, A.4
El-Sankary, W.5
-
6
-
-
0035987895
-
CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes
-
Luo, G., Cunningham, M., Kim, S., Burn, T., Lin, J., Sinz, M., Hamilton, G., Rizzo, C., Jolley, S., Gilbert, D., Downey, A., Mudra, D., Graham, R., Carroll, K., Xie, J., Madan, A., Parkinson, A., Christ, D., Selling, B., LeCluyse, E. and Gan, L. S.: CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes. Drug Metab. Dispos., 30: 795-804 (2002).
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 795-804
-
-
Luo, G.1
Cunningham, M.2
Kim, S.3
Burn, T.4
Lin, J.5
Sinz, M.6
Hamilton, G.7
Rizzo, C.8
Jolley, S.9
Gilbert, D.10
Downey, A.11
Mudra, D.12
Graham, R.13
Carroll, K.14
Xie, J.15
Madan, A.16
Parkinson, A.17
Christ, D.18
Selling, B.19
LeCluyse, E.20
Gan, L.S.21
more..
-
7
-
-
0034777488
-
Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4
-
Hustert, E., Zibat, A., Presecan-Siedel, E., Eiselt, R., Mueller, R., Fuss, C., Brehm, I., Brinkmann, U., Eichelbaum, M., Wojnowski, L. and Burk, O.: Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4. Drug Metab. Dispos., 29: 1454-1459 (2001).
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 1454-1459
-
-
Hustert, E.1
Zibat, A.2
Presecan-Siedel, E.3
Eiselt, R.4
Mueller, R.5
Fuss, C.6
Brehm, I.7
Brinkmann, U.8
Eichelbaum, M.9
Wojnowski, L.10
Burk, O.11
-
8
-
-
0034785945
-
The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants
-
Zhang, J., Kuehl, P., Green, E. D., Touchman, J. W., Watkins, P. B., Daly, A., Hall, S. D., Maurel, P., Relling, M., Brimer, C., Yasuda, K., Wrighton, S. A., Hancock, M., Kim, R. B., Strom, S., Thummel, K., Russell, C. G., Hudson, J. R. Jr., Schuetz, E. G. and Boguski, M. S.: The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants. Pharmacogenetics, 11: 555-572 (2001).
-
(2001)
Pharmacogenetics
, vol.11
, pp. 555-572
-
-
Zhang, J.1
Kuehl, P.2
Green, E.D.3
Touchman, J.W.4
Watkins, P.B.5
Daly, A.6
Hall, S.D.7
Maurel, P.8
Relling, M.9
Brimer, C.10
Yasuda, K.11
Wrighton, S.A.12
Hancock, M.13
Kim, R.B.14
Strom, S.15
Thummel, K.16
Russell, C.G.17
Hudson, J.R.18
Schuetz, E.G.19
Boguski, M.S.20
more..
|