Multifunctional envelope-type nano device for controlled intracellular trafficking and selective targeting in vivo

Journal of Controlled Release

Volumn 190, Issue , 2014, Pages 593-606

  Kajimoto, Kazuaki ^a   Sato, Yusuke ^a   Nakamura, Takashi ^a   Yamada, Yuma ^a   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Active targeting; Endosomal escape; In vivo siRNA delivery; Intracellular trafficking; Non viral vector; Organelle targeting to mitochondria

Indexed keywords

DISEASE CONTROL; DRUG DELIVERY; MEDICAL NANOTECHNOLOGY; NUCLEIC ACIDS; HISTOLOGY; RNA; TISSUE;

ACTIVE TARGETING; ENDOSOMAL ESCAPES; IN-VIVO; INTRACELLULAR TRAFFICKING; NONVIRAL VECTORS;

MITOCHONDRIA;

ANTIGEN; BCG VACCINE; IMMUNOLOGICAL ADJUVANT; LIPID; NANOCARRIER; NANOPARTICLE; NUCLEIC ACID; POLYETHYLENEIMINE; PROHIBITIN; PROHIBITIN TARGETED NANOPARTICLE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; NANOMATERIAL; DF MITO PORTER NANOCARRIER; PEPTIDE;

ADIPOSE TISSUE; ANTIGEN PRESENTATION; APOPTOSIS; BLADDER CANCER; CANCER IMMUNOTHERAPY; CARCINOMA IN SITU; CELL ORGANELLE; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CYTOTOXICITY; DRUG DELIVERY DEVICE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG TARGETING; DRUG TRAFFIC; GENE SILENCING; GENE THERAPY; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR MEMBRANE; INTRACELLULAR TRANSPORT; LIVER PARENCHYMA; MEMBRANE FUSION; MITOCHONDRIAL GENOME; MITOCHONDRIAL TARGETING SIGNAL; MITOCHONDRION; MULTIFUNCTIONAL ENVELOPE TYPE NANO DEVICE; NANODEVICE; NATURAL KILLER T CELL; NONHUMAN; OBESITY; PH; PHASE 1 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; REVIEW; TARGET CELL; TARGET ORGAN; TISSUE REACTION; VACCINATION; VASCULARIZATION; CHEMISTRY; IMMUNOTHERAPY; INTRACELLULAR SPACE; METABOLISM; NANOMEDICINE; NEOPLASMS; PROCEDURES; CANCER ADJUVANT THERAPY; CELL MIGRATION; CLINICAL TRIAL (TOPIC); CONTROLLED DRUG RELEASE; DRUG CONJUGATION; ENDOSOME; PHYSICAL CHEMISTRY;

DRUG DELIVERY SYSTEMS; HUMANS; IMMUNOTHERAPY; INTRACELLULAR SPACE; MITOCHONDRIA; NANOMEDICINE; NANOSTRUCTURES; NEOPLASMS; RNA, SMALL INTERFERING;

EID: 84906786909     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.03.058     Document Type: Review

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