-
1
-
-
52649158262
-
Ectopic fat and insulin resistance
-
A. Lettner, M. Roden, Ectopic fat and insulin resistance, Curr. Diabetes Rep. 8 (3) (2008) 185-191.
-
(2008)
Curr. Diabetes Rep.
, vol.8
, Issue.3
, pp. 185-191
-
-
Lettner, A.1
Roden, M.2
-
2
-
-
70349326750
-
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
-
E. Fabbrini, F. Magkos, B.S. Mohammed, T. Pietka, N.A. Abumrad, B.W. Patterson, et al., Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity, Proc. Natl. Acad. Sci. U. S. A. 106 (36) (2009) 15430-15435.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, Issue.36
, pp. 15430-15435
-
-
Fabbrini, E.1
Magkos, F.2
Mohammed, B.S.3
Pietka, T.4
Abumrad, N.A.5
Patterson, B.W.6
-
3
-
-
0032934826
-
1H NMR spectroscopy study
-
DOI 10.1007/s001250051123
-
M. Krssak, K. Falk Petersen, A. Dresner, L DiPietro, S.M. Vogel, D.L. Rothman, et al., Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study, Diabetologia 42 (1) (1999) 113-116. (Pubitemid 29039748)
-
(1999)
Diabetologia
, vol.42
, Issue.1
, pp. 113-116
-
-
Krssak, M.1
Falk Petersen, K.2
Dresner, A.3
DiPietro, L.4
Vogel, S.M.5
Rothman, D.L.6
Shulman, G.I.7
Roden, M.8
-
4
-
-
0036116231
-
Angiogenesis in adipose tissue
-
A. Bouloumie, K. Lolmede, C. Sengenes, J. Galitzky, M Lafontan, Angiogenesis in adipose tissue, Ann. Endocrinol. (Paris) 63 (2 Pt 1) (2002) 91-95. (Pubitemid 34538250)
-
(2002)
Annales d'Endocrinologie
, vol.63
, Issue.2
, pp. 91-95
-
-
Bouloumie, A.1
Lolmede, K.2
Sengenes, C.3
Galitzky, J.4
Lafontan, M.5
-
5
-
-
34249719581
-
Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels
-
DOI 10.2337/db06-1749
-
S. Nishimura, I. Manabe, M. Nagasaki, Y. Hosoya, H. Yamashita, H. Fujita, et al, Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels, Diabetes 56 (6) (2007) 1517-1526. (Pubitemid 46842598)
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1517-1526
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Hosoya, Y.4
Yamashita, H.5
Fujita, H.6
Ohsugi, M.7
Tobe, K.8
Kadowaki, T.9
Nagai, R.10
Sugiura, S.11
-
6
-
-
68349150756
-
CD8 + effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
S. Nishimura, I. Manabe, M. Nagasaki, K. Eto, H. Yamashita, M. Ohsugi, et al, CD8 + effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity, Nat Med. 15 (8) (2009) 914-920.
-
(2009)
Nat Med.
, vol.15
, Issue.8
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Eto, K.4
Yamashita, H.5
Ohsugi, M.6
-
7
-
-
2942703809
-
Reversal of obesity by targeted ablation of adipose tissue
-
DOI 10.1038/nm1048
-
M.G. Kolonin, P.K. Saha, L Chan, R. Pasqualini, W. Arap, Reversal of obesity by targeted ablation of adipose tissue, Nat Med. 10 (6) (2004) 625-632. (Pubitemid 38796854)
-
(2004)
Nature Medicine
, vol.10
, Issue.6
, pp. 625-632
-
-
Kolonin, M.G.1
Saha, P.K.2
Chan, L.3
Pasqualini, R.4
Arap, W.5
-
8
-
-
81055146759
-
A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys
-
K.F. Barnhart, D.R. Christianson, P.W. Hanley, W.H. Driessen, B.J. Bernacky, W.B. Baze, et al., A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys, Sci. Transl. Med. 3 (108) (2011) 108ra112.
-
(2011)
Sci. Transl. Med.
, vol.3
, Issue.108
-
-
Barnhart, K.F.1
Christianson, D.R.2
Hanley, P.W.3
Driessen, W.H.4
Bernacky, B.J.5
Baze, W.B.6
-
9
-
-
84866552156
-
Vascular-targeted nanotherapy for obesity: Unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery
-
M.N. Hossen, K. Kajimoto, H. Akita, M. Hyodo, H. Harashima, Vascular-targeted nanotherapy for obesity: unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery, J. Control. Release 163 (2) (2012) 101-110.
-
(2012)
J. Control. Release
, vol.163
, Issue.2
, pp. 101-110
-
-
Hossen, M.N.1
Kajimoto, K.2
Akita, H.3
Hyodo, M.4
Harashima, H.5
-
10
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Y. Matsumura, H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumortropic accumulation of proteins and the antitumor agent smancs, Cancer Res. 46 (12 Pt 1) (1986) 6387-6392. (Pubitemid 17221789)
-
(1986)
Cancer Research
, vol.46
, Issue.12
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
11
-
-
84875218436
-
Therapeutic assessment of cytochrome c for the prevention of obesity through endothelial cell-targeted nanoparticulate system
-
January http://dx.doi.org/10.1038/mt2012.256, (Online)
-
M.N. Hossen, K. Kajimoto, H. Akita, M Hyodo, T. Ishitsuka, H. Harashima, Therapeutic assessment of cytochrome c for the prevention of obesity through endothelial cell-targeted nanoparticulate system, Mol. Ther. (January 2013), http://dx.doi.org/10.1038/mt2012.256, (Online).
-
(2013)
Mol. Ther.
-
-
Hossen, M.N.1
Kajimoto, K.2
Akita, H.3
Hyodo, M.4
Ishitsuka, T.5
Harashima, H.6
-
12
-
-
77957017973
-
Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue
-
M.N. Hossen, K. Kajimoto, H. Akita, M. Hyodo, T. Ishitsuka, H. Harashima, Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue, J. Control. Release 147 (2) (2010) 261-268.
-
(2010)
J. Control. Release
, vol.147
, Issue.2
, pp. 261-268
-
-
Hossen, M.N.1
Kajimoto, K.2
Akita, H.3
Hyodo, M.4
Ishitsuka, T.5
Harashima, H.6
-
13
-
-
77952490630
-
Isolation and culture of microvascular endothelial cells from murine inguinal and epididymal adipose tissues
-
K. Kajimoto, M.N. Hossen, K. Hida, N. Ohga, H. Akita, M. Hyodo, et al., Isolation and culture of microvascular endothelial cells from murine inguinal and epididymal adipose tissues, J. Immunol. Methods 357 (1-2) (2010) 43-50.
-
(2010)
J. Immunol. Methods
, vol.357
, Issue.1-2
, pp. 43-50
-
-
Kajimoto, K.1
Hossen, M.N.2
Hida, K.3
Ohga, N.4
Akita, H.5
Hyodo, M.6
-
14
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
DOI 10.1056/NEJM199602013340503
-
R.V. Considine, M.K. Sinha, M.L. Heiman, A. Kriauciunas, T.W. Stephens, M.R. Nyce, et al, Serum immunoreactive leptin concentrations in normal-weight and obese humans, N. Engl. J. Med. 334 (5) (1996) 292-295. (Pubitemid 26033933)
-
(1996)
New England Journal of Medicine
, vol.334
, Issue.5
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, J.P.7
Marco, C.C.8
Mckee, L.J.9
Bauer, T.L.10
Caro, J.F.11
-
15
-
-
17544382289
-
AdipoQ is a novel adipose-specific gene dysregulated in obesity
-
DOI 10.1074/jbc.271.18.10697
-
E. Hu, P. Liang, B.M. Spiegelman, AdipoQis a novel adipose-specific gene dysregulated in obesity, J. Biol. Chem. 271 (18) (1996) 10697-10703. (Pubitemid 26145805)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.18
, pp. 10697-10703
-
-
Hu, E.1
Liang, P.2
Spiegelman, B.M.3
-
16
-
-
0034999667
-
Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
-
DOI 10.1210/jc.86.5.1930
-
C. Weyer, T. Funahashi, S. Tanaka, K. Hotta, Y. Matsuzawa, R.E. Pratley, et al, Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia, J. Clin. Endocrinol. Metab. 86 (5) (2001) 1930-1935. (Pubitemid 32472900)
-
(2001)
Journal of Clinical Endocrinology and Metabolism
, vol.86
, Issue.5
, pp. 1930-1935
-
-
Weyer, C.1
Funahashi, T.2
Tanaka, S.3
Hotta, K.4
Matsuzawa, Y.5
Pratley, R.E.6
Tataranni, P.A.7
-
17
-
-
0026040907
-
Development of muscle insulin resistance after liver insulin resistance in high-fat fed rats
-
E.W. Kraegen, P.W. Clark, A.B. Jenkins, E.A. Daley, D.J. Chisholm, LH. Storlien, Development of muscle insulin resistance after liver insulin resistance in high-fat fed rats, Diabetes 40 (11) (1991) 1397-1403.
-
(1991)
Diabetes
, vol.40
, Issue.11
, pp. 1397-1403
-
-
Kraegen, E.W.1
Clark, P.W.2
Jenkins, A.B.3
Daley, E.A.4
Chisholm, D.J.5
Storlien, L.H.6
-
18
-
-
0036678477
-
Adipose tissue mass can be regulated through the vasculature
-
M.A. Rupnick, D. Panigrahy, C.Y. Zhang, S.M. Dallabrida, B.B. Lowell, R. Langer, M.J. Folkman, et al, Adipose tissue mass can be regulated through the vasculature, Proc. Natl. Acad. Sci. U. S. A. 99 (16) (2002) 10730-10735.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, Issue.16
, pp. 10730-10735
-
-
Rupnick, M.A.1
Panigrahy, D.2
Zhang, C.Y.3
Dallabrida, S.M.4
Lowell, B.B.5
Langer, R.6
Folkman, M.J.7
-
19
-
-
65349182940
-
Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice
-
A. Ejaz, D. Wu, P. Kwan, M. Meydani, Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice, J. Nutr. 139 (5) (2009) 919-925.
-
(2009)
J. Nutr.
, vol.139
, Issue.5
, pp. 919-925
-
-
Ejaz, A.1
Wu, D.2
Kwan, P.3
Meydani, M.4
-
20
-
-
0036120713
-
Matrix metalloproteinase inhibition impairs adipose tissue development in mice
-
DOI 10.1161/hq0302.104522
-
H.R. Lijnen, E. Maquoi, L.B. Hansen, B. Van Hoef, L. Frederix, D. Collen, Matrix metal-loproteinase inhibition impairs adipose tissue development in mice, Arterioscler. Thromb. Vasc. Biol. 22 (3) (2002) 374-379. (Pubitemid 34218741)
-
(2002)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.22
, Issue.3
, pp. 374-379
-
-
Lijnen, H.R.1
Maquoi, E.2
Hansen, L.B.3
Van Hoef, B.4
Frederix, L.5
Collen, D.6
-
21
-
-
3042786130
-
Angiogenesis inhibitor, TNP-470, prevents diet induced and genetic obesity in mice
-
DOI 10.1161/01.RES.0000132745.76882.70
-
E. Brakenhielm, R. Cao, B. Gao, B. Angelin, B. Cannon, P. Parini, Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice, Circ. Res. 94 (12) (2004) 1579-1588. (Pubitemid 38856965)
-
(2004)
Circulation Research
, vol.94
, Issue.12
, pp. 1579-1588
-
-
Brakenhielm, E.1
Cao, R.2
Gao, B.3
Angelin, B.4
Cannon, B.5
Parini, P.6
Cao, Y.7
-
22
-
-
0348230958
-
-
S.P. Weisberg, D. McCann, M. Desai, M. Rosenbaum, R.L. Leibel, A.W. Ferrante, Obesity is associated with macrophage accumulation inadipose tissue,J. Clin. Invest. 112 (12) (2003) 1796-1808.
-
(2003)
Obesity is Associated with Macrophage Accumulation Inadipose Tissue,J. Clin. Invest.
, vol.112
, Issue.12
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
23
-
-
34848851922
-
Angiogenesis modulates adipogenesis and obesity
-
DOI 10.1172/JCI32239
-
Y. Cao, Angiogenesis modulates adipogenesis and obesity, J. Clin. Invest. 117 (9) (2007) 2362-2368. (Pubitemid 47494333)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.9
, pp. 2362-2368
-
-
Cao, Y.1
-
24
-
-
75849165542
-
Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases
-
Y. Cao, Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases, Nat. Rev. Drug Discov. 9 (2) (2010) 107-115.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, Issue.2
, pp. 107-115
-
-
Cao, Y.1
-
25
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
DOI 10.1038/nm788
-
T. Yamauchi, J. Kamon, Y. Minokoshi, Y. Ito, H. Waki, S. Uchida, et al., Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase, Nat. Med. 8 (11) (2002) 1288-1295. (Pubitemid 35373562)
-
(2002)
Nature Medicine
, vol.8
, Issue.11
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
Yamashita, S.7
Noda, M.8
Kita, S.9
Ueki, K.10
Eto, K.11
Akanuma, Y.12
Froguel, P.13
Foufelle, F.14
Ferre, P.15
Carling, D.16
Kimura, S.17
Nagai, R.18
Kahn, B.B.19
Kadowaki, T.20
more..
-
26
-
-
36849067019
-
Nanocarriers as an emerging platform for cancer therapy
-
P. Dan, M.J. Karp, H. Seungpyo, C.F. Omid, M. Rimona, L. Robert, Nanocarriers as an emerging platform for cancer therapy, Nat. Nanotechnol. 2 (12) (2007) 751-760.
-
(2007)
Nat. Nanotechnol.
, vol.2
, Issue.12
, pp. 751-760
-
-
Dan, P.1
Karp, M.J.2
Seungpyo, H.3
Omid, C.F.4
Rimona, M.5
Robert, L.6
-
27
-
-
33749265990
-
Multivalent effects of RGD peptides obtained by nanoparticle display
-
DOI 10.1021/jm060515m
-
X. Montet, M. Funovics, K. Montet-Abou, R. Weissleder, L. Josephson, Multivalent effects of RGD peptides obtained by nanoparticle display, J. Med. Chem. 49 (20) (2006) 6087-6093. (Pubitemid 44484952)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.20
, pp. 6087-6093
-
-
Montet, X.1
Funovics, M.2
Montet-Abou, K.3
Weissleder, R.4
Josephson, L.5
|