CD1d-restricted and TCR-mediated activation of V(α)14 NKT cells by glycosylceramides

Science

Volumn 278, Issue 5343, 1997, Pages 1626-1629

  Kawano, Tetsu ^a   Cui, Junqing ^a   Koezuka, Yasuhiko ^a   Toura, Isao ^a   Kaneko, Yoshikatsu ^a   Motoki, Kazuhiro ^a   Ueno, Hitomi ^a   Nakagawa, Ryusuke ^a   Sato, Hiroshi ^a   Kondo, Eisuke ^a   Koseki, Haruhiko ^a   Taniguchi, Masaru ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSYLCERAMIDE;

ANTIGEN EXPRESSION; ARTICLE; CELL PROLIFERATION; GENE SEQUENCE; KILLER CELL; LIGAND BINDING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; SPLEEN CELL;

ANIMALS; ANTIGENS, CD1; CARBOHYDRATE CONFORMATION; CELLS, CULTURED; CERAMIDES; CEREBROSIDES; COCULTURE TECHNIQUES; GALACTOSYLCERAMIDES; GLUCOSYLCERAMIDES; KILLER CELLS, NATURAL; LIGANDS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTE SUBSETS;

EID: 0030696696     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.278.5343.1626     Document Type: Article

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59. We thank T. Sakai and K. Akimoto (Kirn Brewery) for preparation of synthetic glycolipids and Y. Sanai (Tokyo Metropolitan Institute) for helpful discussion. We are grateful to H. Tanabe for secretarial assistance. Supported in part by a Grant-in-Aid for Scientific Research on Priority Areas (08282103) from the Ministry of Education, Culture, and Science of Japan and a research grant from Taisho Pharmaceutical.