On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids

Gene Therapy

Volumn 8, Issue 15, 2001, Pages 1188-1196

  Hafez, I M ^a   Maurer, N ^a   Cullis, P R ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Inex Pharmaceuticals Corporation   (Canada)

Author keywords

Gene therapy; Lipid polymorphism; Lipoplexes; Transfection

Indexed keywords

ANION; ANTISENSE OLIGONUCLEOTIDE; CATION; CHOLESTEROL; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; LIPID; MEMBRANE LIPID; NUCLEIC ACID; PHOSPHOLIPID; PLASMID DNA;

ARTICLE; CELL MEMBRANE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOPLASM; ENDOSOME; GENE TARGETING; GENETIC TRANSFECTION; LIPID BILAYER; MEMBRANE STABILIZATION; MEMBRANE TRANSPORT; PRIORITY JOURNAL;

CATIONS; CELL MEMBRANE; CHOLESTEROL; GENE THERAPY; GLYCEROPHOSPHOLIPIDS; HUMANS; LIPID BILAYERS; LIPOSOMES; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHATIDYLETHANOLAMINES; TRANSFECTION;

EID: 0034882516     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301506     Document Type: Article

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