-
1
-
-
0032551829
-
Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system
-
Agrawal A., Eastman Q.M., Schatz D.G. Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature. 394:1998;744-751.
-
(1998)
Nature
, vol.394
, pp. 744-751
-
-
Agrawal, A.1
Eastman, Q.M.2
Schatz, D.G.3
-
2
-
-
0037417795
-
Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice
-
Akamatsu Y., Monroe R., Dudley D.D., Elkin S.K., Gärtner F., Talukder S.R., Takahama Y., Alt F.W., Bassing C.H., Oettinger M.A. Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice. Proc. Natl. Acad. Sci. USA. 100:2003;1209-1214.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1209-1214
-
-
Akamatsu, Y.1
Monroe, R.2
Dudley, D.D.3
Elkin, S.K.4
Gärtner, F.5
Talukder, S.R.6
Takahama, Y.7
Alt, F.W.8
Bassing, C.H.9
Oettinger, M.A.10
-
3
-
-
0041646843
-
Joining of immunoglobulin heavy chain gene segments: Implications from a chromosome with evidence of three D-JH fusions
-
Alt F.W., Baltimore D. Joining of immunoglobulin heavy chain gene segments. implications from a chromosome with evidence of three D-JH fusions Proc. Natl. Acad. Sci. USA. 79:1982;4118-4122.
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 4118-4122
-
-
Alt, F.W.1
Baltimore, D.2
-
4
-
-
0018929067
-
Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain
-
Alt F.W., Enea V., Bothwell A.L.M., Baltimore D. Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain. Cell. 21:1980;1-12.
-
(1980)
Cell
, vol.21
, pp. 1-12
-
-
Alt, F.W.1
Enea, V.2
Bothwell, A.L.M.3
Baltimore, D.4
-
5
-
-
0021442649
-
Ordered rearrangement of immunoglobulin heavy chain variable region segments
-
Alt F.W., Yancopoulos G.D., Blackwell T.K., Wood C., Thomas E., Boss M., Coffman R., Rosenberg N., Tonegawa S., Baltimore D. Ordered rearrangement of immunoglobulin heavy chain variable region segments. EMBO J. 3:1984;1209-1219.
-
(1984)
EMBO J.
, vol.3
, pp. 1209-1219
-
-
Alt, F.W.1
Yancopoulos, G.D.2
Blackwell, T.K.3
Wood, C.4
Thomas, E.5
Boss, M.6
Coffman, R.7
Rosenberg, N.8
Tonegawa, S.9
Baltimore, D.10
-
6
-
-
0035667196
-
Early death and severe lymphopenia caused by ubiquitous expression of the Rag1 and Rag2 genes in mice
-
Barreto V., Marques R., Demengeot J. Early death and severe lymphopenia caused by ubiquitous expression of the Rag1 and Rag2 genes in mice. Eur. J. Immunol. 31:2001;3763-3772.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 3763-3772
-
-
Barreto, V.1
Marques, R.2
Demengeot, J.3
-
7
-
-
85077949203
-
-
Bassing, C.H., and Alt, F.W. (2004). H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity. Cell Cycle 3
-
Bassing, C.H., and Alt, F.W. (2004). H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity. Cell Cycle 3, http://www.landesbioscience.com/journals/cc/abstract.php?id=684 .
-
-
-
-
8
-
-
0034214049
-
Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule
-
Bassing C.H., Alt F.W., Hughes M.M., D'Auteuil M., Wehrly T., Woodman B.B., Gartner F., White J.M., Davidson L., Sleckman B.P. Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule. Nature. 405:2000;583-586.
-
(2000)
Nature
, vol.405
, pp. 583-586
-
-
Bassing, C.H.1
Alt, F.W.2
Hughes, M.M.3
D'auteuil, M.4
Wehrly, T.5
Woodman, B.B.6
Gartner, F.7
White, J.M.8
Davidson, L.9
Sleckman, B.P.10
-
9
-
-
0036240127
-
The mechanism and regulation of chromosomal V(D)J recombination
-
Bassing C.H., Swat W., Alt F.W. The mechanism and regulation of chromosomal V(D)J recombination. Cell. 109(Suppl):2002;S45-S55.
-
(2002)
Cell
, vol.109
, Issue.SUPPL
-
-
Bassing, C.H.1
Swat, W.2
Alt, F.W.3
-
10
-
-
0042991379
-
Histone H2AX: A dosage-dependent suppressor of oncogenic translocations and tumors
-
Bassing C.H., Suh H., Ferguson D.O., Chua K.F., Manis J., Eckersdorff M., Gleason M., Bronson R., Lee C., Alt F.W. Histone H2AX. a dosage-dependent suppressor of oncogenic translocations and tumors Cell. 114:2003;359-370.
-
(2003)
Cell
, vol.114
, pp. 359-370
-
-
Bassing, C.H.1
Suh, H.2
Ferguson, D.O.3
Chua, K.F.4
Manis, J.5
Eckersdorff, M.6
Gleason, M.7
Bronson, R.8
Lee, C.9
Alt, F.W.10
-
11
-
-
0021230278
-
Site-specific recombination between immunoglobulin D and JH segments that were introduced into the genome of a murine pre-B cell line
-
Blackwell T.K., Alt F.W. Site-specific recombination between immunoglobulin D and JH segments that were introduced into the genome of a murine pre-B cell line. Cell. 37:1984;105-112.
-
(1984)
Cell
, vol.37
, pp. 105-112
-
-
Blackwell, T.K.1
Alt, F.W.2
-
12
-
-
0018093829
-
A complete immunoglobulin gene is created by somatic recombination
-
Brack C., Hirama M., Lenhard-Schuller R., Tonegawa S. A complete immunoglobulin gene is created by somatic recombination. Cell. 15:1978;1-14.
-
(1978)
Cell
, vol.15
, pp. 1-14
-
-
Brack, C.1
Hirama, M.2
Lenhard-Schuller, R.3
Tonegawa, S.4
-
13
-
-
0002225186
-
A modification of Jerne's theory of antibody production using the concept of clonal selection
-
Burnet F.M. A modification of Jerne's theory of antibody production using the concept of clonal selection. Austr. Jour. Sci. 20:1957;67-69.
-
(1957)
Austr. Jour. Sci.
, vol.20
, pp. 67-69
-
-
Burnet, F.M.1
-
14
-
-
0035936833
-
Contribution of receptor editing to the antibody repertoire
-
Casellas R., Shih T.-A.Y., Kleinewietfeld M., Rakonjac J., Nemazee D., Rajewsky K., Nussenzweig M.C. Contribution of receptor editing to the antibody repertoire. Science. 291:2001;1541-1544.
-
(2001)
Science
, vol.291
, pp. 1541-1544
-
-
Casellas, R.1
Shih, T.-A.Y.2
Kleinewietfeld, M.3
Rakonjac, J.4
Nemazee, D.5
Rajewsky, K.6
Nussenzweig, M.C.7
-
15
-
-
0037031604
-
OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin k genes
-
Casellas R., Jankovic M., Meyer G., Gazumyan A., Luo Y., Roeder R.G., Nussenzweig M.C. OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin k genes. Cell. 110:2002;575-585.
-
(2002)
Cell
, vol.110
, pp. 575-585
-
-
Casellas, R.1
Jankovic, M.2
Meyer, G.3
Gazumyan, A.4
Luo, Y.5
Roeder, R.G.6
Nussenzweig, M.C.7
-
16
-
-
0042991383
-
H2AX haploinsufficiency modifies genomic stability and tumor susceptibility (2003)
-
Celeste A., Difilippantonio S., Difilippantonio M.J., Fernandez-Capetillo O., Pilch D.R., Sedelnikova O.A., Eckhaus M., Ried T., Bonner W.M., Nussenzweig A. H2AX haploinsufficiency modifies genomic stability and tumor susceptibility (2003). Cell. 114:2003;371-383.
-
(2003)
Cell
, vol.114
, pp. 371-383
-
-
Celeste, A.1
Difilippantonio, S.2
Difilippantonio, M.J.3
Fernandez-Capetillo, O.4
Pilch, D.R.5
Sedelnikova, O.A.6
Eckhaus, M.7
Ried, T.8
Bonner, W.M.9
Nussenzweig, A.10
-
17
-
-
0037452080
-
Transcription-targeted DNA deamination by the AID antibody diversification enzyme
-
Chaudhuri J., Tian M., Khuong C., Chua K., Pinaud E., Alt F.W. Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature. 422:2003;726-730.
-
(2003)
Nature
, vol.422
, pp. 726-730
-
-
Chaudhuri, J.1
Tian, M.2
Khuong, C.3
Chua, K.4
Pinaud, E.5
Alt, F.W.6
-
18
-
-
0037332014
-
Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements
-
Chowdhury D., Sen R. Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements. Immunity. 18:2003;229-241.
-
(2003)
Immunity
, vol.18
, pp. 229-241
-
-
Chowdhury, D.1
Sen, R.2
-
19
-
-
0026029613
-
The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system
-
Chun J.J., Schatz D.G., Oettinger M.A., Jaenisch R., Baltimore D. The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Cell. 64:1991;189-200.
-
(1991)
Cell
, vol.64
, pp. 189-200
-
-
Chun, J.J.1
Schatz, D.G.2
Oettinger, M.A.3
Jaenisch, R.4
Baltimore, D.5
-
21
-
-
0345505218
-
Nonhomologous end joining and V(D)J recombination require an additional factor
-
Dai Y., Kysela B., Hanakahi L.A., Manolis K., Riballo E., Stumm M., Harville T.O., West S.C., Oettinger M.A., Jeggo P.A. Nonhomologous end joining and V(D)J recombination require an additional factor. Proc. Natl. Acad. Sci. USA. 100:2003;2462-2467.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2462-2467
-
-
Dai, Y.1
Kysela, B.2
Hanakahi, L.A.3
Manolis, K.4
Riballo, E.5
Stumm, M.6
Harville, T.O.7
West, S.C.8
Oettinger, M.A.9
Jeggo, P.A.10
-
22
-
-
0023720148
-
T-cell antigen receptor genes and T-cell recognition
-
Davis M.M., Bjorkman P.J. T-cell antigen receptor genes and T-cell recognition. Nature. 334:1988;395-402.
-
(1988)
Nature
, vol.334
, pp. 395-402
-
-
Davis, M.M.1
Bjorkman, P.J.2
-
24
-
-
0032861880
-
Signaling pathways that control V(D)J recombination
-
Desiderio S., Lee J. Signaling pathways that control V(D)J recombination. Curr. Top. Microbiol. Immunol. 245:2000;31-56.
-
(2000)
Curr. Top. Microbiol. Immunol.
, vol.245
, pp. 31-56
-
-
Desiderio, S.1
Lee, J.2
-
25
-
-
0013800975
-
The molecular basis of antibody formation: A paradox
-
Dreyer W.J., Bennett J.C. The molecular basis of antibody formation. a paradox Proc. Natl. Acad. Sci. USA. 54:1965;864-869.
-
(1965)
Proc. Natl. Acad. Sci. USA
, vol.54
, pp. 864-869
-
-
Dreyer, W.J.1
Bennett, J.C.2
-
26
-
-
0242610985
-
Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice
-
Dudley D.D., Sekiguchi J., Zhu C., Sadofsky M.J., Whitlow S., DeVido J., Monroe R.J., Bassing C.H., Alt F.W. Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice. J. Exp. Med. 198:2003;1439-1450.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1439-1450
-
-
Dudley, D.D.1
Sekiguchi, J.2
Zhu, C.3
Sadofsky, M.J.4
Whitlow, S.5
Devido, J.6
Monroe, R.J.7
Bassing, C.H.8
Alt, F.W.9
-
27
-
-
0018843979
-
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH
-
Early P., Huang H., Davis M., Calame K., Hood L. An immunoglobulin heavy chain variable region gene is generated from three segments of DNA. VH, D and JH Cell. 19:1980;981-992.
-
(1980)
Cell
, vol.19
, pp. 981-992
-
-
Early, P.1
Huang, H.2
Davis, M.3
Calame, K.4
Hood, L.5
-
28
-
-
0029864993
-
Initiation of V(D)J recombination in vitro obeying the 12/23 rule
-
Eastman Q.M., Leu T.M.J., Schatz D.G. Initiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature. 380:1996;85-88.
-
(1996)
Nature
, vol.380
, pp. 85-88
-
-
Eastman, Q.M.1
Leu, T.M.J.2
Schatz, D.G.3
-
29
-
-
0037447338
-
The C-terminal portion of RAG2 protects against transposition in vitro
-
Elkin S.K., Matthews A.G., Oettinger M.A. The C-terminal portion of RAG2 protects against transposition in vitro. EMBO J. 22:2003;1931-1938.
-
(2003)
EMBO J.
, vol.22
, pp. 1931-1938
-
-
Elkin, S.K.1
Matthews, A.G.2
Oettinger, M.A.3
-
30
-
-
0025177032
-
Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate
-
Ferrier P., Krippl B., Blackwell T.K., Furley A.J.W., Suh H., Winoto A., Cook W.D., Hood L., Costantini F., Alt F.W. Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate. EMBO J. 9:1990;117-125.
-
(1990)
EMBO J.
, vol.9
, pp. 117-125
-
-
Ferrier, P.1
Krippl, B.2
Blackwell, T.K.3
Furley, A.J.W.4
Suh, H.5
Winoto, A.6
Cook, W.D.7
Hood, L.8
Costantini, F.9
Alt, F.W.10
-
31
-
-
0033918155
-
B-cell repertoire formation: Role of the recombination signal sequence in non-random V segment utilization
-
Feeney A.J., Tang A., Ogwaro K.M. B-cell repertoire formation. role of the recombination signal sequence in non-random V segment utilization Immunol. Rev. 175:2000;59-69.
-
(2000)
Immunol. Rev.
, vol.175
, pp. 59-69
-
-
Feeney, A.J.1
Tang, A.2
Ogwaro, K.M.3
-
32
-
-
0034094425
-
The RAG proteins and V(D)J recombination: Complexes, ends, and transposition
-
Fugmann S.D., Lee A.I., Shockett P.E., Villey I.J., Schatz D.G. The RAG proteins and V(D)J recombination. complexes, ends, and transposition Annu. Rev. Immunol. 18:2000;495-527.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 495-527
-
-
Fugmann, S.D.1
Lee, A.I.2
Shockett, P.E.3
Villey, I.J.4
Schatz, D.G.5
-
33
-
-
0026687789
-
The basis for the mechanistic bias for deletional over inversional V(D)J recombination
-
Gauss G.H., Lieber M.R. The basis for the mechanistic bias for deletional over inversional V(D)J recombination. Genes Dev. 6:1992;1553-1561.
-
(1992)
Genes Dev.
, vol.6
, pp. 1553-1561
-
-
Gauss, G.H.1
Lieber, M.R.2
-
34
-
-
0035997348
-
V(D)J recombination: RAG proteins, repair factors, and regulation
-
Gellert M. V(D)J recombination. RAG proteins, repair factors, and regulation Annu. Rev. Biochem. 71:2002;101-132.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 101-132
-
-
Gellert, M.1
-
35
-
-
0027452074
-
Mice lacking TdT: Mature animals with an immature lymphocyte repertoire
-
Gilfillan S., Dierich A., Lerneur M., Benoist C., Mathis D. Mice lacking TdT. mature animals with an immature lymphocyte repertoire Science. 261:1993;1175-1178.
-
(1993)
Science
, vol.261
, pp. 1175-1178
-
-
Gilfillan, S.1
Dierich, A.2
Lerneur, M.3
Benoist, C.4
Mathis, D.5
-
36
-
-
0023659483
-
Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals
-
Hesse J.E., Lieber M.R., Gellert M., Mizuuchi K. Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals. Cell. 49:1987;775-783.
-
(1987)
Cell
, vol.49
, pp. 775-783
-
-
Hesse, J.E.1
Lieber, M.R.2
Gellert, M.3
Mizuuchi, K.4
-
37
-
-
0034969086
-
Factors and forces controlling V(D)J recombination
-
Hesslein D.G.T., Schatz D.G. Factors and forces controlling V(D)J recombination. Adv. Immunol. 78:2001;169-232.
-
(2001)
Adv. Immunol.
, vol.78
, pp. 169-232
-
-
Hesslein, D.G.T.1
Schatz, D.G.2
-
38
-
-
0037229028
-
Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments
-
Hesslein D.G.T., Pflugh D.L., Chowdhury D., Bothwell A.L.M., Sen R., Schatz D.G. Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments. Genes Dev. 17:2003;37-42.
-
(2003)
Genes Dev.
, vol.17
, pp. 37-42
-
-
Hesslein, D.G.T.1
Pflugh, D.L.2
Chowdhury, D.3
Bothwell, A.L.M.4
Sen, R.5
Schatz, D.G.6
-
39
-
-
0032555758
-
DNA transposition by the RAG1 and RAG2 proteins: A possible source of oncogenic translocations
-
Hiom K., Melek M., Gellert M. DNA transposition by the RAG1 and RAG2 proteins. a possible source of oncogenic translocations Cell. 94:1998;463-470.
-
(1998)
Cell
, vol.94
, pp. 463-470
-
-
Hiom, K.1
Melek, M.2
Gellert, M.3
-
40
-
-
0011118362
-
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions
-
Hozumi N., Tonegawa S. Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proc. Natl. Acad. Sci. USA. 73:1976;3628-3632.
-
(1976)
Proc. Natl. Acad. Sci. USA
, vol.73
, pp. 3628-3632
-
-
Hozumi, N.1
Tonegawa, S.2
-
41
-
-
0036261707
-
Sensing and repairing DNA double-strand breaks
-
Jackson S.P. Sensing and repairing DNA double-strand breaks. Carcinogenesis. 23:2002;687-696.
-
(2002)
Carcinogenesis
, vol.23
, pp. 687-696
-
-
Jackson, S.P.1
-
42
-
-
0038783576
-
A conserved transcriptional enhancer regulates RAG gene expression in developing B cells
-
Hsu L.-Y., Lauring J., Liang H.-E., Greenbaum S., Cado D., Zhuang Y., Schlissel M.S. A conserved transcriptional enhancer regulates RAG gene expression in developing B cells. Immunity. 19:2003;105-117.
-
(2003)
Immunity
, vol.19
, pp. 105-117
-
-
Hsu, L.-Y.1
Lauring, J.2
Liang, H.-E.3
Greenbaum, S.4
Cado, D.5
Zhuang, Y.6
Schlissel, M.S.7
-
43
-
-
0036682598
-
Ordered assembly of the V(D)J synaptic complex ensures accurate recombination
-
Jones J.M., Gellert M. Ordered assembly of the V(D)J synaptic complex ensures accurate recombination. EMBO J. 21:2002;4162-4171.
-
(2002)
EMBO J.
, vol.21
, pp. 4162-4171
-
-
Jones, J.M.1
Gellert, M.2
-
44
-
-
0037242580
-
Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted V(D)J recombination in nonlymphoid cells
-
Jung D., Bassing C.H., Fugmann S.D., Cheng H.-L., Schatz D.G., Alt F.W. Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted V(D)J recombination in nonlymphoid cells. Immunity. 18:2003;65-74.
-
(2003)
Immunity
, vol.18
, pp. 65-74
-
-
Jung, D.1
Bassing, C.H.2
Fugmann, S.D.3
Cheng, H.-L.4
Schatz, D.G.5
Alt, F.W.6
-
45
-
-
0037086702
-
Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair
-
Kang J., Bronson R.T., Xu Y. Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J. 21:2002;1447-1455.
-
(2002)
EMBO J.
, vol.21
, pp. 1447-1455
-
-
Kang, J.1
Bronson, R.T.2
Xu, Y.3
-
46
-
-
0035093737
-
DNA double-strand breaks: Signaling, repair and the cancer connection
-
Khanna K.K., Jackson S.P. DNA double-strand breaks. signaling, repair and the cancer connection Nat. Genet. 27:2001;247-254.
-
(2001)
Nat. Genet.
, vol.27
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
47
-
-
0036525695
-
Allelic exclusion at the TCRb locus
-
Khor B., Sleckman B.P. Allelic exclusion at the TCRb locus. Curr. Opin. Immunol. 14:2002;230-234.
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 230-234
-
-
Khor, B.1
Sleckman, B.P.2
-
48
-
-
0842343144
-
Targeted disruption of mu chain membrane exon causes loss of allelic exclusion
-
Kitamura D., Rajewsky K. Targeted disruption of mu chain membrane exon causes loss of allelic exclusion. Nature. 69:1992;823-831.
-
(1992)
Nature
, vol.69
, pp. 823-831
-
-
Kitamura, D.1
Rajewsky, K.2
-
49
-
-
0027369562
-
Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes
-
Komori T., Okada A., Stewart T., Alt F.W. Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes. Science. 261:1993;1171-1175.
-
(1993)
Science
, vol.261
, pp. 1171-1175
-
-
Komori, T.1
Okada, A.2
Stewart, T.3
Alt, F.W.4
-
50
-
-
0037625160
-
Gene segment selection in V(D)J recombination: Accessibility and beyond
-
Krangel M.S. Gene segment selection in V(D)J recombination. accessibility and beyond Nat. Immunol. 4:2003;624-630.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 624-630
-
-
Krangel, M.S.1
-
51
-
-
0033638506
-
Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA
-
Kwon J., Morshead K.B., Guyon J.R., Kingston R.E., Oettinger M.A. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol. Cell. 6:2000;1037-1048.
-
(2000)
Mol. Cell
, vol.6
, pp. 1037-1048
-
-
Kwon, J.1
Morshead, K.B.2
Guyon, J.R.3
Kingston, R.E.4
Oettinger, M.A.5
-
52
-
-
0037023361
-
Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
-
Kosak S.T., Skok J.A., Medina K.L., Riblet R., Le Beau M.M., Fisher A.G., Singh H. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science. 296:2002;158-162.
-
(2002)
Science
, vol.296
, pp. 158-162
-
-
Kosak, S.T.1
Skok, J.A.2
Medina, K.L.3
Riblet, R.4
Le Beau, M.M.5
Fisher, A.G.6
Singh, H.7
-
53
-
-
0028276377
-
Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers
-
Lauzurica P., Krangel M.S. Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers. J. Exp. Med. 179:1994;1913-1921.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1913-1921
-
-
Lauzurica, P.1
Krangel, M.S.2
-
54
-
-
0028048275
-
The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
-
Lewis S.M. The mechanism of V(D)J joining. lessons from molecular, immunological, and comparative analyses Adv. Immunol. 56:1994;27-49.
-
(1994)
Adv. Immunol.
, vol.56
, pp. 27-49
-
-
Lewis, S.M.1
-
55
-
-
0021240073
-
Joining of Vk to Jk gene segments in a retroviral vector introduced into lymphoid cells
-
Lewis S., Gifford A., Baltimore D. Joining of Vk to Jk gene segments in a retroviral vector introduced into lymphoid cells. Nature. 308:1984;425-428.
-
(1984)
Nature
, vol.308
, pp. 425-428
-
-
Lewis, S.1
Gifford, A.2
Baltimore, D.3
-
56
-
-
0036850786
-
The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development
-
Liang H.-E., Hsu L.-Y., Cado D., Cowell L.G., Kelsoe G., Schlissel M.S. The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development. Immunity. 17:2002;639-651.
-
(2002)
Immunity
, vol.17
, pp. 639-651
-
-
Liang, H.-E.1
Hsu, L.-Y.2
Cado, D.3
Cowell, L.G.4
Kelsoe, G.5
Schlissel, M.S.6
-
57
-
-
0028453264
-
The mechanism of V(D)J recombination: Site-specificity, reaction fidelity and immunologic diversity
-
Lieber M.R., Chang C.-P., Gallo M., Gauss G., Gerstein R., Islas A. The mechanism of V(D)J recombination. site-specificity, reaction fidelity and immunologic diversity Semin. Immunol. 6:1994;143-153.
-
(1994)
Semin. Immunol.
, vol.6
, pp. 143-153
-
-
Lieber, M.R.1
Chang, C.-P.2
Gallo, M.3
Gauss, G.4
Gerstein, R.5
Islas, A.6
-
58
-
-
0037155703
-
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
-
Ma Y., Pannicke U., Schwarz K., Lieber M.R. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell. 108:2002;781-794.
-
(2002)
Cell
, vol.108
, pp. 781-794
-
-
Ma, Y.1
Pannicke, U.2
Schwarz, K.3
Lieber, M.R.4
-
59
-
-
0036776756
-
The pre-B cell receptor and its role in proliferation and Ig heavy chain allelic exclusion
-
Mårtensson I.-L., Rolink A., Melchers F., Mundt C., Licence S., Shimizu T. The pre-B cell receptor and its role in proliferation and Ig heavy chain allelic exclusion. Semin. Immunol. 14:2002;335-342.
-
(2002)
Semin. Immunol.
, vol.14
, pp. 335-342
-
-
Mårtensson, I.-L.1
Rolink, A.2
Melchers, F.3
Mundt, C.4
Licence, S.5
Shimizu, T.6
-
60
-
-
0011088657
-
Sequences of five potential recombination sites encoded close to an immunoglobulin k constant region gene
-
Max E.E., Seidman J.G., Leder P. Sequences of five potential recombination sites encoded close to an immunoglobulin k constant region gene. Proc. Natl. Acad. Sci. USA. 76:1979;3450-3454.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 3450-3454
-
-
Max, E.E.1
Seidman, J.G.2
Leder, P.3
-
61
-
-
0028805853
-
Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
-
McBlane J.F., van Gent D.C., Ramsden D.A., Romeo C., Cuomo C.A., Gellert M., Oettinger M.A. Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps. Cell. 83:1995;387-395.
-
(1995)
Cell
, vol.83
, pp. 387-395
-
-
Mcblane, J.F.1
Van Gent, D.C.2
Ramsden, D.A.3
Romeo, C.4
Cuomo, C.A.5
Gellert, M.6
Oettinger, M.A.7
-
62
-
-
0024564420
-
The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein
-
McGuire E.A., Hockett R.D., Pollock K.M., Bartholdi M.F., O'Brien S.J., Korsmeyer S.J. The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein. Mol. Cell. Biol. 9:1989;2124-2132.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 2124-2132
-
-
Mcguire, E.A.1
Hockett, R.D.2
Pollock, K.M.3
Bartholdi, M.F.4
O'brien, S.J.5
Korsmeyer, S.J.6
-
63
-
-
0034695501
-
A role for histone acetylation in the developmental regulation of V(D)J recombination
-
McMurry M.T., Krangel M.S. A role for histone acetylation in the developmental regulation of V(D)J recombination. Science. 287:2000;495-498.
-
(2000)
Science
, vol.287
, pp. 495-498
-
-
Mcmurry, M.T.1
Krangel, M.S.2
-
64
-
-
0345146909
-
In vivo transposition mediated by V(D)J recombinase in human T lymphocytes
-
Messier T.L., O'Neill J.P., Hou S.M., Nicklas J.A., Finette B.A. In vivo transposition mediated by V(D)J recombinase in human T lymphocytes. EMBO J. 22:2003;1381-1388.
-
(2003)
EMBO J.
, vol.22
, pp. 1381-1388
-
-
Messier, T.L.1
O'neill, J.P.2
Hou, S.M.3
Nicklas, J.A.4
Finette, B.A.5
-
65
-
-
0037660900
-
The role of DNA breaks in genomic instability and tumorigenesis
-
Mills K.D., Ferguson D.O., Alt F.W. The role of DNA breaks in genomic instability and tumorigenesis. Immunol. Rev. 194:2003;77-95.
-
(2003)
Immunol. Rev.
, vol.194
, pp. 77-95
-
-
Mills, K.D.1
Ferguson, D.O.2
Alt, F.W.3
-
66
-
-
0016315585
-
Sequence analysis of immunoglobulin light chain messenger RNA
-
Milstein C., Brownlee G.G., Cartwright E.M., Jarvis J.M., Proudfoot N.J. Sequence analysis of immunoglobulin light chain messenger RNA. Nature. 252:1974;354-359.
-
(1974)
Nature
, vol.252
, pp. 354-359
-
-
Milstein, C.1
Brownlee, G.G.2
Cartwright, E.M.3
Jarvis, J.M.4
Proudfoot, N.J.5
-
67
-
-
0026585781
-
RAG-1-deficient mice have no mature B and T lymphocytes
-
Mombaerts P., Iacomini J., Johnson R.S., Herrup K., Tonegawa S., Papaioannou V.E. RAG-1-deficient mice have no mature B and T lymphocytes. Cell. 68:1992;869-877.
-
(1992)
Cell
, vol.68
, pp. 869-877
-
-
Mombaerts, P.1
Iacomini, J.2
Johnson, R.S.3
Herrup, K.4
Tonegawa, S.5
Papaioannou, V.E.6
-
68
-
-
0033180183
-
RAG2:gfp knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues
-
a
-
Monroe R.J., Seidl K.J., Gaertner F., Han S., Chen F., Sekiguchi J., Wang J., Ferrini R., Davidson L., Kelsoe G., Alt F.W. RAG2:gfp knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues. Immunity. 11:1999;201-212. a.
-
(1999)
Immunity
, vol.11
, pp. 201-212
-
-
Monroe, R.J.1
Seidl, K.J.2
Gaertner, F.3
Han, S.4
Chen, F.5
Sekiguchi, J.6
Wang, J.7
Ferrini, R.8
Davidson, L.9
Kelsoe, G.10
Alt, F.W.11
-
69
-
-
0033607175
-
RAG2 is regulated differentially in B and T cells by elements 5′ of the promoter
-
b
-
Monroe R.J., Chen F., Ferrini R., Davidson L., Alt F.W. RAG2 is regulated differentially in B and T cells by elements 5′ of the promoter. Proc. Natl. Acad. Sci. USA. 96:1999;12713-12718. b.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12713-12718
-
-
Monroe, R.J.1
Chen, F.2
Ferrini, R.3
Davidson, L.4
Alt, F.W.5
-
70
-
-
0032526136
-
K chain monoallelic demethylation and the establishment of allelic exclusion
-
Mostoslavsky R., Singh N., Kirillov A., Pelanda R., Cedar H., Chess A., Bergman Y. k chain monoallelic demethylation and the establishment of allelic exclusion. Genes Dev. 12:1998;1801-1811.
-
(1998)
Genes Dev.
, vol.12
, pp. 1801-1811
-
-
Mostoslavsky, R.1
Singh, N.2
Kirillov, A.3
Pelanda, R.4
Cedar, H.5
Chess, A.6
Bergman, Y.7
-
71
-
-
0035829551
-
Asynchronous replication and allelic exclusion in the immune system
-
Mostoslavsky R., Singh N., Tenzen T., Goldmit M., Gabay C., Elizur S., Qi P., Reubinoff B.E., Chess A., Cedar H., Bergman Y. Asynchronous replication and allelic exclusion in the immune system. Nature. 414:2001;221-225.
-
(2001)
Nature
, vol.414
, pp. 221-225
-
-
Mostoslavsky, R.1
Singh, N.2
Tenzen, T.3
Goldmit, M.4
Gabay, C.5
Elizur, S.6
Qi, P.7
Reubinoff, B.E.8
Chess, A.9
Cedar, H.10
Bergman, Y.11
-
73
-
-
0034093662
-
Regulation of RAG expression in developing lymphocytes
-
Nagaoka H., Yu W., Nussenzweig M.C. Regulation of RAG expression in developing lymphocytes. Curr. Opin. Immunol. 12:2000;187-190.
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 187-190
-
-
Nagaoka, H.1
Yu, W.2
Nussenzweig, M.C.3
-
74
-
-
0034045874
-
Receptor selection in B and T lymphocytes
-
Nemazee D. Receptor selection in B and T lymphocytes. Annu. Rev. Immunol. 18:2000;19-51.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 19-51
-
-
Nemazee, D.1
-
75
-
-
0023189116
-
Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu
-
Nussenzweig M.C., Shaw A.C., Sinn E., Danner D.B., Holmes K.L., Morse H.C. 3rd, Leder P. Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu. Science. 236:1987;816-819.
-
(1987)
Science
, vol.236
, pp. 816-819
-
-
Nussenzweig, M.C.1
Shaw, A.C.2
Sinn, E.3
Danner, D.B.4
Holmes, K.L.5
Morse III, H.C.6
Leder, P.7
-
76
-
-
0025301095
-
RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
-
Oettinger M.A., Schatz D.G., Gorka C., Baltimore D. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science. 248:1990;1517-1523.
-
(1990)
Science
, vol.248
, pp. 1517-1523
-
-
Oettinger, M.A.1
Schatz, D.G.2
Gorka, C.3
Baltimore, D.4
-
77
-
-
0141920616
-
DNA-Rag protein interactions in the control of selective D gene utilization in the TCRb locus
-
Olaru A., Patterson D.N., Villey I., Livak F. DNA-Rag protein interactions in the control of selective D gene utilization in the TCRb locus. J. Immunol. 171:2003;3605-3611.
-
(2003)
J. Immunol.
, vol.171
, pp. 3605-3611
-
-
Olaru, A.1
Patterson, D.N.2
Villey, I.3
Livak, F.4
-
78
-
-
0013816340
-
Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues
-
Pernis B., Chiappino G., Kelus A.S., Gell P.G.H. Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues. J. Exp. Med. 122:1965;853-875.
-
(1965)
J. Exp. Med.
, vol.122
, pp. 853-875
-
-
Pernis, B.1
Chiappino, G.2
Kelus, A.S.3
Gell, P.G.H.4
-
79
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky K. Clonal selection and learning in the antibody system. Nature. 381:1996;751-758.
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
80
-
-
0038293484
-
Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
-
Ramiro A.R., Stavropoulos P., Jankovic M., Nussenzweig M.C. Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand. Nat. Immunol. 4:2003;452-456.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 452-456
-
-
Ramiro, A.R.1
Stavropoulos, P.2
Jankovic, M.3
Nussenzweig, M.C.4
-
81
-
-
0036531895
-
Histone H2A variants H2AX and H2AZ
-
Redon C., Pilch D., Rogakou E., Sedelnikova O., Newrock K., Bonner W. Histone H2A variants H2AX and H2AZ. Curr. Opin. Genet. Dev. 12:2002;162-169.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 162-169
-
-
Redon, C.1
Pilch, D.2
Rogakou, E.3
Sedelnikova, O.4
Newrock, K.5
Bonner, W.6
-
82
-
-
0021680505
-
Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice
-
Ritchie K.A., Brinster R.L., Storb U. Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice. Nature. 312:1984;517-520.
-
(1984)
Nature
, vol.312
, pp. 517-520
-
-
Ritchie, K.A.1
Brinster, R.L.2
Storb, U.3
-
83
-
-
0036932453
-
Leaky scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice
-
Rooney S., Sekiguchi J.M., Zhu C., Cheng H.-L., Manis J., Whitlow S., DeVido J., Foy D., Chaudhuri J., Lombard D., Alt F.W. Leaky scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice. Mol. Cell. 10:2002;1379-1390.
-
(2002)
Mol. Cell
, vol.10
, pp. 1379-1390
-
-
Rooney, S.1
Sekiguchi, J.M.2
Zhu, C.3
Cheng, H.-L.4
Manis, J.5
Whitlow, S.6
Devido, J.7
Foy, D.8
Chaudhuri, J.9
Lombard, D.10
Alt, F.W.11
-
84
-
-
0141720776
-
Restraining the V(D)J recombinase
-
Roth D.B. Restraining the V(D)J recombinase. Nat. Rev. Immunol. 3:2003;656-666.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 656-666
-
-
Roth, D.B.1
-
85
-
-
0021993025
-
Transmission and expression of a specific pair of rearranged immunoglobulin mu and kappa genes in a transgenic mouse line
-
Rusconi S., Köhler G. Transmission and expression of a specific pair of rearranged immunoglobulin mu and kappa genes in a transgenic mouse line. Nature. 314:1985;330-334.
-
(1985)
Nature
, vol.314
, pp. 330-334
-
-
Rusconi, S.1
Köhler, G.2
-
86
-
-
0018627375
-
Sequences at the somatic recombination sites of immunoglobulin light-chain genes
-
Sakano H., Hüppi K., Heinrich G., Tonegawa S. Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature. 280:1979;288-294.
-
(1979)
Nature
, vol.280
, pp. 288-294
-
-
Sakano, H.1
Hüppi, K.2
Heinrich, G.3
Tonegawa, S.4
-
87
-
-
0024281350
-
Stable expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts
-
Schatz D.G., Baltimore D. Stable expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts. Cell. 53:1988;107-115.
-
(1988)
Cell
, vol.53
, pp. 107-115
-
-
Schatz, D.G.1
Baltimore, D.2
-
88
-
-
0024846088
-
The V(D)J recombination activating gene, RAG-1
-
Schatz D.G., Oettinger M.A., Baltimore D. The V(D)J recombination activating gene, RAG-1. Cell. 59:1989;1035-1048.
-
(1989)
Cell
, vol.59
, pp. 1035-1048
-
-
Schatz, D.G.1
Oettinger, M.A.2
Baltimore, D.3
-
89
-
-
0018832503
-
Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangements in heavy chain V-region gene segments
-
Schilling J., Clevinger B., Davie J.M., Hood L. Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangements in heavy chain V-region gene segments. Nature. 283:1980;35-40.
-
(1980)
Nature
, vol.283
, pp. 35-40
-
-
Schilling, J.1
Clevinger, B.2
Davie, J.M.3
Hood, L.4
-
90
-
-
0037023491
-
Does Artemis end the hunt for the hairpin-opening activity in V(D)J recombination?
-
Schlissel M.S. Does Artemis end the hunt for the hairpin-opening activity in V(D)J recombination? Cell. 109:2002;1-4.
-
(2002)
Cell
, vol.109
, pp. 1-4
-
-
Schlissel, M.S.1
-
91
-
-
0011251475
-
Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis
-
Seidman J.G., Leder A., Edgell M.H., Polsky F., Tilghman S.M., Tiemeier D.C., Leder P. Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis. Proc. Natl. Acad. Sci. USA. 75:1978;3881-3885.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 3881-3885
-
-
Seidman, J.G.1
Leder, A.2
Edgell, M.H.3
Polsky, F.4
Tilghman, S.M.5
Tiemeier, D.C.6
Leder, P.7
-
92
-
-
0018657190
-
A k-immunoglobulin gene is formed by site-specific recombination without further somatic mutation
-
Seidman J.G., Max E.E., Leder P. A k-immunoglobulin gene is formed by site-specific recombination without further somatic mutation. Nature. 280:1979;370-375.
-
(1979)
Nature
, vol.280
, pp. 370-375
-
-
Seidman, J.G.1
Max, E.E.2
Leder, P.3
-
93
-
-
0035697242
-
Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs
-
Sekiguchi J., Whitlow S., Alt F.W. Increased accumulation of hybrid V(D) J joins in cells expressing truncated versus full-length RAGs. Mol. Cell. 8:2001;1383-1390.
-
(2001)
Mol. Cell
, vol.8
, pp. 1383-1390
-
-
Sekiguchi, J.1
Whitlow, S.2
Alt, F.W.3
-
94
-
-
0026581936
-
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
-
Shinkai Y., Rathbun G., Lam K.-P., Oltz E.M., Stewart V., Mendelsohn M., Charron J., Datta M., Young F., Stall A.M., Alt F.W. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell. 68:1992;855-867.
-
(1992)
Cell
, vol.68
, pp. 855-867
-
-
Shinkai, Y.1
Rathbun, G.2
Lam, K.-P.3
Oltz, E.M.4
Stewart, V.5
Mendelsohn, M.6
Charron, J.7
Datta, M.8
Young, F.9
Stall, A.M.10
Alt, F.W.11
-
95
-
-
0037125979
-
Regulation of V(D)J recombination: A dominant role for promoter positioning in gene segment assembly
-
Sikes M.L., Meade A., Tripathi R., Krangel M.S., Oltz E.M. Regulation of V(D)J recombination. a dominant role for promoter positioning in gene segment assembly Proc. Natl. Acad. Sci. USA. 99:2002;12309-12314.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12309-12314
-
-
Sikes, M.L.1
Meade, A.2
Tripathi, R.3
Krangel, M.S.4
Oltz, E.M.5
-
96
-
-
0034608888
-
Mechanisms that direct ordered assembly of T cell receptor b locus V, D, and J gene segments
-
Sleckman B.P., Bassing C.H., Hughes M.M., Okada A., D'Auteuil M., Wehrly T.D., Woodman B.B., Davidson L., Chen J., Alt F.W. Mechanisms that direct ordered assembly of T cell receptor b locus V, D, and J gene segments. Proc. Natl. Acad. Sci. USA. 97:2000;7975-7980.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7975-7980
-
-
Sleckman, B.P.1
Bassing, C.H.2
Hughes, M.M.3
Okada, A.4
D'auteuil, M.5
Wehrly, T.D.6
Woodman, B.B.7
Davidson, L.8
Chen, J.9
Alt, F.W.10
-
97
-
-
0029894165
-
Cell-type specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
-
Stanhope-Baker P., Hudson K.M., Shaffer A.L., Constantinescu A., Schlissel M.S. Cell-type specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro. Cell. 85:1996;887-897.
-
(1996)
Cell
, vol.85
, pp. 887-897
-
-
Stanhope-Baker, P.1
Hudson, K.M.2
Shaffer, A.L.3
Constantinescu, A.4
Schlissel, M.S.5
-
98
-
-
0021054081
-
Methylation patterns of immunoglobulin genes in lymphoid cells: Correlation of expression and differentiation with undermethylation
-
Storb U., Arp B. Methylation patterns of immunoglobulin genes in lymphoid cells. correlation of expression and differentiation with undermethylation Proc. Natl. Acad. Sci. USA. 80:1983;6642-6646.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 6642-6646
-
-
Storb, U.1
Arp, B.2
-
99
-
-
1042301422
-
-
Swanson, P.C., Volkmer, D., and Wang, L. (2003). Full-length RAG-2, and not full-length RAG-1, specifically suppresses RAG-mediated transposition, but not hybrid joint formation or disintegration. J. Biol. Chem.
-
Swanson, P.C., Volkmer, D., and Wang, L. (2003). Full-length RAG-2, and not full-length RAG-1, specifically suppresses RAG-mediated transposition, but not hybrid joint formation or disintegration. J. Biol. Chem. 10.1074/jbc.M311100200 .
-
-
-
-
100
-
-
0027156278
-
Impairment of V(D)J recombination in double-strand break repair mutants
-
Taccioli G.E., Rathbun G., Oltz E., Stamato T., Jeggo P.A., Alt F.W. Impairment of V(D)J recombination in double-strand break repair mutants. Science. 260:1993;207-210.
-
(1993)
Science
, vol.260
, pp. 207-210
-
-
Taccioli, G.E.1
Rathbun, G.2
Oltz, E.3
Stamato, T.4
Jeggo, P.A.5
Alt, F.W.6
-
102
-
-
0028867419
-
New insights into V(D)J recombination and its role in the evolution of the immune system
-
Thompson C.B. New insights into V(D)J recombination and its role in the evolution of the immune system. Immunity. 3:1995;531-539.
-
(1995)
Immunity
, vol.3
, pp. 531-539
-
-
Thompson, C.B.1
-
103
-
-
0037221032
-
Targeting of Vb to Db rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors
-
Tillman R.E., Wooley A.L., Khor B., Wehrly T.D., Little C.A., Sleckman B.P. Targeting of Vb to Db rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors. J. Immunol. 170:2003;5-9.
-
(2003)
J. Immunol.
, vol.170
, pp. 5-9
-
-
Tillman, R.E.1
Wooley, A.L.2
Khor, B.3
Wehrly, T.D.4
Little, C.A.5
Sleckman, B.P.6
-
104
-
-
0020534965
-
Somatic generation of antibody diversity
-
Tonegawa S. Somatic generation of antibody diversity. Nature. 302:1983;575-581.
-
(1983)
Nature
, vol.302
, pp. 575-581
-
-
Tonegawa, S.1
-
105
-
-
0037447298
-
Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2
-
Tsai C.-L., Schatz D.G. Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2. EMBO J. 22:2003;1922-1930.
-
(2003)
EMBO J.
, vol.22
, pp. 1922-1930
-
-
Tsai, C.-L.1
Schatz, D.G.2
-
106
-
-
0025324784
-
Chromosomal translocations in lymphoid neoplasia: A reappraisal of the recombinase model
-
Tycko B., Sklar J. Chromosomal translocations in lymphoid neoplasia. a reappraisal of the recombinase model Cancer Cells. 2:1990;1-8.
-
(1990)
Cancer Cells
, vol.2
, pp. 1-8
-
-
Tycko, B.1
Sklar, J.2
-
107
-
-
0018165360
-
Multiplicity of germline genes specifying a group of related mouse k chains with implications for the generation of immunoglobulin diversity
-
Valbuena O., Marcu K.B., Weigert M., Perry R.P. Multiplicity of germline genes specifying a group of related mouse k chains with implications for the generation of immunoglobulin diversity. Nature. 276:1978;780-784.
-
(1978)
Nature
, vol.276
, pp. 780-784
-
-
Valbuena, O.1
Marcu, K.B.2
Weigert, M.3
Perry, R.P.4
-
108
-
-
0028979702
-
Initiation of V(D)J recombination in a cell-free system
-
van Gent D.C., McBlane J.F., Ramsden D.A., Sadofsky M.J., Hesse J.E., Gellert M. Initiation of V(D)J recombination in a cell-free system. Cell. 81:1995;925-934.
-
(1995)
Cell
, vol.81
, pp. 925-934
-
-
Van Gent, D.C.1
Mcblane, J.F.2
Ramsden, D.A.3
Sadofsky, M.J.4
Hesse, J.E.5
Gellert, M.6
-
109
-
-
0029967722
-
Similarities between initiation of V(D)J recombination and retroviral integration
-
a
-
van Gent D.C., Mizuuchi K., Gellert M. Similarities between initiation of V(D)J recombination and retroviral integration. Science. 271:1996;1592-1594. a.
-
(1996)
Science
, vol.271
, pp. 1592-1594
-
-
Van Gent, D.C.1
Mizuuchi, K.2
Gellert, M.3
-
110
-
-
0030009253
-
The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination
-
b
-
van Gent D.C., Ramsden D.A., Gellert M. The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination. Cell. 85:1996;107-113. b.
-
(1996)
Cell
, vol.85
, pp. 107-113
-
-
Van Gent, D.C.1
Ramsden, D.A.2
Gellert, M.3
-
111
-
-
0022385230
-
A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes
-
Weaver D., Costantini F., Imanishi-Kari T., Baltimore D. A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes. Cell. 42:1985;117-127.
-
(1985)
Cell
, vol.42
, pp. 117-127
-
-
Weaver, D.1
Costantini, F.2
Imanishi-Kari, T.3
Baltimore, D.4
-
112
-
-
0018068687
-
Rearrangement of genetic information may produce immunoglobulin diversity
-
Weigert M., Gatmaitan L., Loh E., Schilling J., Hood L. Rearrangement of genetic information may produce immunoglobulin diversity. Nature. 276:1978;785-790.
-
(1978)
Nature
, vol.276
, pp. 785-790
-
-
Weigert, M.1
Gatmaitan, L.2
Loh, E.3
Schilling, J.4
Hood, L.5
-
113
-
-
0021983551
-
Developmentally controlled and tissue-specific expression of unrearranged VH gene segments
-
Yancopoulos G.D., Alt F.W. Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell. 40:1985;271-281.
-
(1985)
Cell
, vol.40
, pp. 271-281
-
-
Yancopoulos, G.D.1
Alt, F.W.2
-
114
-
-
0022549940
-
Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase
-
Yancopoulos G.D., Blackwell T.K., Suh H., Hood L., Alt F.W. Introduced T cell receptor variable region gene segments recombine in pre-B cells. evidence that B and T cells use a common recombinase Cell. 44:1986;251-259.
-
(1986)
Cell
, vol.44
, pp. 251-259
-
-
Yancopoulos, G.D.1
Blackwell, T.K.2
Suh, H.3
Hood, L.4
Alt, F.W.5
-
115
-
-
0033549813
-
Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization
-
a
-
Yu W., Nagaoka H., Jankovic M., Misulovin Z., Suh H., Rolink A., Melchers F., Meffre E., Nussenzweig M.C. Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization. Nature. 400:1999;682-687. a.
-
(1999)
Nature
, vol.400
, pp. 682-687
-
-
Yu, W.1
Nagaoka, H.2
Jankovic, M.3
Misulovin, Z.4
Suh, H.5
Rolink, A.6
Melchers, F.7
Meffre, E.8
Nussenzweig, M.C.9
-
116
-
-
0033551866
-
Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5′ of RAG2
-
b
-
Yu W., Misulovin Z., Suh H., Hardy R.R., Jankovic M., Yannoutsos N., Nussenzweig M.C. Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5′ of RAG2. Science. 285:1999;1080-1084. b.
-
(1999)
Science
, vol.285
, pp. 1080-1084
-
-
Yu, W.1
Misulovin, Z.2
Suh, H.3
Hardy, R.R.4
Jankovic, M.5
Yannoutsos, N.6
Nussenzweig, M.C.7
-
117
-
-
0037335702
-
The RAG1 N-terminal domain is an E3 ubiquitin ligase
-
Yurchenko V., Xue Z., Sadofsky M. The RAG1 N-terminal domain is an E3 ubiquitin ligase. Genes Dev. 17:2003;581-585.
-
(2003)
Genes Dev.
, vol.17
, pp. 581-585
-
-
Yurchenko, V.1
Xue, Z.2
Sadofsky, M.3
|