-
1
-
-
0027109075
-
Cancer. P53, guardian of the genome
-
D.P. Lane Cancer. p53, guardian of the genome Nature 358 1992 15 16
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
2
-
-
69949085788
-
Genome instability, cancer and aging
-
A.Y. Maslov, and J. Vijg Genome instability, cancer and aging Biochim. Biophys. Acta 1790 2009 963 969
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, pp. 963-969
-
-
Maslov, A.Y.1
Vijg, J.2
-
3
-
-
0028455420
-
Does wild-type p53 play a role in normal cell differentiation?
-
V. Rotter, R. Aloni-Grinstein, D. Schwartz, N.B. Elkind, A. Simons, R. Wolkowicz, M. Lavigne, P. Beserman, A. Kapon, and N. Goldfinger Does wild-type p53 play a role in normal cell differentiation? Semin. Cancer Biol. 5 1994 229 236
-
(1994)
Semin. Cancer Biol.
, vol.5
, pp. 229-236
-
-
Rotter, V.1
Aloni-Grinstein, R.2
Schwartz, D.3
Elkind, N.B.4
Simons, A.5
Wolkowicz, R.6
Lavigne, M.7
Beserman, P.8
Kapon, A.9
Goldfinger, N.10
-
4
-
-
56649118849
-
P53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner
-
A. Molchadsky, I. Shats, N. Goldfinger, M. Pevsner-Fischer, M. Olson, A. Rinon, E. Tzahor, G. Lozano, D. Zipori, R. Sarig, and V. Rotter p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner PLoS One 3 2008
-
(2008)
PLoS One
, vol.3
-
-
Molchadsky, A.1
Shats, I.2
Goldfinger, N.3
Pevsner-Fischer, M.4
Olson, M.5
Rinon, A.6
Tzahor, E.7
Lozano, G.8
Zipori, D.9
Sarig, R.10
Rotter, V.11
-
5
-
-
84877579607
-
P53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity
-
A. Molchadsky, O. Ezra, P.G. Amendola, D. Krantz, I. Kogan-Sakin, Y. Buganim, N. Rivlin, N. Goldfinger, V. Folgiero, R. Falcioni, R. Sarig, and V. Rotter p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity Cell Death Differ. 20 2013 774 783
-
(2013)
Cell Death Differ.
, vol.20
, pp. 774-783
-
-
Molchadsky, A.1
Ezra, O.2
Amendola, P.G.3
Krantz, D.4
Kogan-Sakin, I.5
Buganim, Y.6
Rivlin, N.7
Goldfinger, N.8
Folgiero, V.9
Falcioni, R.10
Sarig, R.11
Rotter, V.12
-
6
-
-
13944273471
-
P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
-
T. Lin, C. Chao, S. Saito, S.J. Mazur, M.E. Murphy, E. Appella, and Y. Xu p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression Nat. Cell Biol. 7 2005 165 171
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 165-171
-
-
Lin, T.1
Chao, C.2
Saito, S.3
Mazur, S.J.4
Murphy, M.E.5
Appella, E.6
Xu, Y.7
-
7
-
-
0027452415
-
Wild type p53 functions as a control protein in the differentiation pathway of the B-cell lineage
-
R. Aloni-Grinstein, I. Zan-Bar, I. Alboum, N. Goldfinger, and V. Rotter Wild type p53 functions as a control protein in the differentiation pathway of the B-cell lineage Oncogene 8 1993 3297 3305
-
(1993)
Oncogene
, vol.8
, pp. 3297-3305
-
-
Aloni-Grinstein, R.1
Zan-Bar, I.2
Alboum, I.3
Goldfinger, N.4
Rotter, V.5
-
8
-
-
32244436592
-
P53 suppresses the self-renewal of adult neural stem cells
-
K. Meletis, V. Wirta, S.M. Hede, M. Nister, J. Lundeberg, and J. Frisen p53 suppresses the self-renewal of adult neural stem cells Development 133 2006 363 369
-
(2006)
Development
, vol.133
, pp. 363-369
-
-
Meletis, K.1
Wirta, V.2
Hede, S.M.3
Nister, M.4
Lundeberg, J.5
Frisen, J.6
-
9
-
-
40249093059
-
A core Klf circuitry regulates self-renewal of embryonic stem cells
-
J. Jiang, Y.S. Chan, Y.H. Loh, J. Cai, G.Q. Tong, C.A. Lim, P. Robson, S. Zhong, and H.H. Ng A core Klf circuitry regulates self-renewal of embryonic stem cells Nat. Cell Biol. 10 2008 353 360
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 353-360
-
-
Jiang, J.1
Chan, Y.S.2
Loh, Y.H.3
Cai, J.4
Tong, G.Q.5
Lim, C.A.6
Robson, P.7
Zhong, S.8
Ng, H.H.9
-
10
-
-
79952283482
-
P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
-
C.J. Chang, C.H. Chao, W. Xia, J.Y. Yang, Y. Xiong, C.W. Li, W.H. Yu, S.K. Rehman, J.L. Hsu, H.H. Lee, M. Liu, C.T. Chen, D. Yu, and M.C. Hung p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs Nat. Cell Biol. 13 2011 317 323
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 317-323
-
-
Chang, C.J.1
Chao, C.H.2
Xia, W.3
Yang, J.Y.4
Xiong, Y.5
Li, C.W.6
Yu, W.H.7
Rehman, S.K.8
Hsu, J.L.9
Lee, H.H.10
Liu, M.11
Chen, C.T.12
Yu, D.13
Hung, M.C.14
-
11
-
-
84872309358
-
P53 Counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition
-
R. Brosh, Y. Assia-Alroy, A. Molchadsky, C. Bornstein, E. Dekel, S. Madar, Y. Shetzer, N. Rivlin, N. Goldfinger, R. Sarig, and V. Rotter p53 Counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition Cell Death Differ. 20 2013 312 320
-
(2013)
Cell Death Differ.
, vol.20
, pp. 312-320
-
-
Brosh, R.1
Assia-Alroy, Y.2
Molchadsky, A.3
Bornstein, C.4
Dekel, E.5
Madar, S.6
Shetzer, Y.7
Rivlin, N.8
Goldfinger, N.9
Sarig, R.10
Rotter, V.11
-
12
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
T. Reya, S.J. Morrison, M.F. Clarke, and I.L. Weissman Stem cells, cancer, and cancer stem cells Nature 414 2001 105 111
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
13
-
-
33745433769
-
Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation
-
M. Miura, Y. Miura, H.M. Padilla-Nash, A.A. Molinolo, B. Fu, V. Patel, B.M. Seo, W. Sonoyama, J.J. Zheng, C.C. Baker, W. Chen, T. Ried, and S. Shi Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation Stem Cells 24 2006 1095 1103
-
(2006)
Stem Cells
, vol.24
, pp. 1095-1103
-
-
Miura, M.1
Miura, Y.2
Padilla-Nash, H.M.3
Molinolo, A.A.4
Fu, B.5
Patel, V.6
Seo, B.M.7
Sonoyama, W.8
Zheng, J.J.9
Baker, C.C.10
Chen, W.11
Ried, T.12
Shi, S.13
-
14
-
-
67649159970
-
TAp63 prevents premature aging by promoting adult stem cell maintenance
-
X. Su, M. Paris, Y.J. Gi, K.Y. Tsai, M.S. Cho, Y.L. Lin, J.A. Biernaskie, S. Sinha, C. Prives, L.H. Pevny, F.D. Miller, and E.R. Flores TAp63 prevents premature aging by promoting adult stem cell maintenance Cell Stem Cell 5 2009 64 75
-
(2009)
Cell Stem Cell
, vol.5
, pp. 64-75
-
-
Su, X.1
Paris, M.2
Gi, Y.J.3
Tsai, K.Y.4
Cho, M.S.5
Lin, Y.L.6
Biernaskie, J.A.7
Sinha, S.8
Prives, C.9
Pevny, L.H.10
Miller, F.D.11
Flores, E.R.12
-
15
-
-
49449096907
-
Stem/progenitor cells in lung development, injury repair, and regeneration
-
D. Warburton, L. Perin, R. Defilippo, S. Bellusci, W. Shi, and B. Driscoll Stem/progenitor cells in lung development, injury repair, and regeneration Proc. Am. Thorac. Soc. 5 2008 703 706
-
(2008)
Proc. Am. Thorac. Soc.
, vol.5
, pp. 703-706
-
-
Warburton, D.1
Perin, L.2
Defilippo, R.3
Bellusci, S.4
Shi, W.5
Driscoll, B.6
-
16
-
-
0346562866
-
Derivation of embryonic germ cells and male gametes from embryonic stem cells
-
N. Geijsen, M. Horoschak, K. Kim, J. Gribnau, K. Eggan, and G.Q. Daley Derivation of embryonic germ cells and male gametes from embryonic stem cells Nature 427 2004 148 154
-
(2004)
Nature
, vol.427
, pp. 148-154
-
-
Geijsen, N.1
Horoschak, M.2
Kim, K.3
Gribnau, J.4
Eggan, K.5
Daley, G.Q.6
-
17
-
-
0037133550
-
Embryonic stem cells and somatic cells differ in mutation frequency and type
-
R.B. Cervantes, J.R. Stringer, C. Shao, J.A. Tischfield, and P.J. Stambrook Embryonic stem cells and somatic cells differ in mutation frequency and type Proc. Natl. Acad. Sci. USA 99 2002 3586 3590
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3586-3590
-
-
Cervantes, R.B.1
Stringer, J.R.2
Shao, C.3
Tischfield, J.A.4
Stambrook, P.J.5
-
18
-
-
66449121507
-
Stem cells use distinct self-renewal programs at different ages
-
B.P. Levi, and S.J. Morrison Stem cells use distinct self-renewal programs at different ages Cold Spring Harb. Symp. Quant. Biol. 73 2008 539 553
-
(2008)
Cold Spring Harb. Symp. Quant. Biol.
, vol.73
, pp. 539-553
-
-
Levi, B.P.1
Morrison, S.J.2
-
19
-
-
0000155376
-
The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles
-
J.B. Gurdon The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles J. Embryol. Exp. Morphol. 10 1962 622 640
-
(1962)
J. Embryol. Exp. Morphol.
, vol.10
, pp. 622-640
-
-
Gurdon, J.B.1
-
20
-
-
0000331391
-
Adult frogs derived from the nuclei of single somatic cells
-
J.B. Gurdon Adult frogs derived from the nuclei of single somatic cells Dev. Biol. 4 1962 256 273
-
(1962)
Dev. Biol.
, vol.4
, pp. 256-273
-
-
Gurdon, J.B.1
-
21
-
-
0022367980
-
Plasticity of the differentiated state
-
H.M. Blau, G.K. Pavlath, E.C. Hardeman, C.P. Chiu, L. Silberstein, S.G. Webster, S.C. Miller, and C. Webster Plasticity of the differentiated state Science 230 1985 758 766
-
(1985)
Science
, vol.230
, pp. 758-766
-
-
Blau, H.M.1
Pavlath, G.K.2
Hardeman, E.C.3
Chiu, C.P.4
Silberstein, L.5
Webster, S.G.6
Miller, S.C.7
Webster, C.8
-
22
-
-
0020960766
-
Cytoplasmic activation of human nuclear genes in stable heterocaryons
-
H.M. Blau, C.P. Chiu, and C. Webster Cytoplasmic activation of human nuclear genes in stable heterocaryons Cell 32 1983 1171 1180
-
(1983)
Cell
, vol.32
, pp. 1171-1180
-
-
Blau, H.M.1
Chiu, C.P.2
Webster, C.3
-
23
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
24
-
-
84892940152
-
Nonviral delivery for reprogramming to pluripotency and differentiation
-
H.J. Park, J. Shin, J. Kim, and S.W. Cho Nonviral delivery for reprogramming to pluripotency and differentiation Arch. Pharm. Res. 37 2014 107 119
-
(2014)
Arch. Pharm. Res.
, vol.37
, pp. 107-119
-
-
Park, H.J.1
Shin, J.2
Kim, J.3
Cho, S.W.4
-
25
-
-
84885619736
-
Deterministic direct reprogramming of somatic cells to pluripotency
-
Y. Rais, A. Zviran, S. Geula, O. Gafni, E. Chomsky, S. Viukov, A.A. Mansour, I. Caspi, V. Krupalnik, M. Zerbib, I. Maza, N. Mor, D. Baran, L. Weinberger, D.A. Jaitin, D. Lara-Astiaso, R. Blecher-Gonen, Z. Shipony, Z. Mukamel, T. Hagai, S. Gilad, D. Amann-Zalcenstein, A. Tanay, I. Amit, N. Novershtern, and J.H. Hanna Deterministic direct reprogramming of somatic cells to pluripotency Nature 502 2013 65 70
-
(2013)
Nature
, vol.502
, pp. 65-70
-
-
Rais, Y.1
Zviran, A.2
Geula, S.3
Gafni, O.4
Chomsky, E.5
Viukov, S.6
Mansour, A.A.7
Caspi, I.8
Krupalnik, V.9
Zerbib, M.10
Maza, I.11
Mor, N.12
Baran, D.13
Weinberger, L.14
Jaitin, D.A.15
Lara-Astiaso, D.16
Blecher-Gonen, R.17
Shipony, Z.18
Mukamel, Z.19
Hagai, T.20
Gilad, S.21
Amann-Zalcenstein, D.22
Tanay, A.23
Amit, I.24
Novershtern, N.25
Hanna, J.H.26
more..
-
26
-
-
84877978530
-
Mechanisms and models of somatic cell reprogramming
-
Y. Buganim, D.A. Faddah, and R. Jaenisch Mechanisms and models of somatic cell reprogramming Nat. Rev. Genet. 14 2013 427 439
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 427-439
-
-
Buganim, Y.1
Faddah, D.A.2
Jaenisch, R.3
-
27
-
-
84866369892
-
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase
-
Y. Buganim, D.A. Faddah, A.W. Cheng, E. Itskovich, S. Markoulaki, K. Ganz, S.L. Klemm, A. van Oudenaarden, and R. Jaenisch Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase Cell 150 2012 1209 1222
-
(2012)
Cell
, vol.150
, pp. 1209-1222
-
-
Buganim, Y.1
Faddah, D.A.2
Cheng, A.W.3
Itskovich, E.4
Markoulaki, S.5
Ganz, K.6
Klemm, S.L.7
Van Oudenaarden, A.8
Jaenisch, R.9
-
28
-
-
77954922985
-
Stem cells in cancer: Instigators and propagators?
-
M.R. Alison, S. Islam, and N.A. Wright Stem cells in cancer: instigators and propagators? J. Cell Sci. 123 2010 2357 2368
-
(2010)
J. Cell Sci.
, vol.123
, pp. 2357-2368
-
-
Alison, M.R.1
Islam, S.2
Wright, N.A.3
-
29
-
-
0022891340
-
Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
H.F. Dvorak Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing N. Engl. J. Med. 315 1986 1650 1659
-
(1986)
N. Engl. J. Med.
, vol.315
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
30
-
-
77953700950
-
Targeting Notch to target cancer stem cells
-
A. Pannuti, K. Foreman, P. Rizzo, C. Osipo, T. Golde, B. Osborne, and L. Miele Targeting Notch to target cancer stem cells Clin. Cancer Res. 16 2010 3141 3152
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 3141-3152
-
-
Pannuti, A.1
Foreman, K.2
Rizzo, P.3
Osipo, C.4
Golde, T.5
Osborne, B.6
Miele, L.7
-
32
-
-
84875219387
-
Cancer stem cells and their role in metastasis
-
Y. Shiozawa, B. Nie, K.J. Pienta, T.M. Morgan, and R.S. Taichman Cancer stem cells and their role in metastasis Pharmacol. Ther. 138 2013 285 293
-
(2013)
Pharmacol. Ther.
, vol.138
, pp. 285-293
-
-
Shiozawa, Y.1
Nie, B.2
Pienta, K.J.3
Morgan, T.M.4
Taichman, R.S.5
-
33
-
-
22244433866
-
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
-
L. Patrawala, T. Calhoun, R. Schneider-Broussard, J. Zhou, K. Claypool, and D.G. Tang Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic Cancer Res. 65 2005 6207 6219
-
(2005)
Cancer Res.
, vol.65
, pp. 6207-6219
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Zhou, J.4
Claypool, K.5
Tang, D.G.6
-
34
-
-
2342601849
-
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
-
Y. Yuan, H. Shen, D.S. Franklin, D.T. Scadden, and T. Cheng In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C Nat. Cell Biol. 6 2004 436 442
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 436-442
-
-
Yuan, Y.1
Shen, H.2
Franklin, D.S.3
Scadden, D.T.4
Cheng, T.5
-
35
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
-
T. Cheng, N. Rodrigues, H. Shen, Y. Yang, D. Dombkowski, M. Sykes, and D.T. Scadden Hematopoietic stem cell quiescence maintained by p21cip1/waf1 Science 287 2000 1804 1808
-
(2000)
Science
, vol.287
, pp. 1804-1808
-
-
Cheng, T.1
Rodrigues, N.2
Shen, H.3
Yang, Y.4
Dombkowski, D.5
Sykes, M.6
Scadden, D.T.7
-
36
-
-
33644826473
-
Roots and stems: Stem cells in cancer
-
K. Polyak, and W.C. Hahn Roots and stems: stem cells in cancer Nat. Med. 12 2006 296 300
-
(2006)
Nat. Med.
, vol.12
, pp. 296-300
-
-
Polyak, K.1
Hahn, W.C.2
-
37
-
-
70349638289
-
Tumour-initiating cells: Challenges and opportunities for anticancer drug discovery
-
B.B. Zhou, H. Zhang, M. Damelin, K.G. Geles, J.C. Grindley, and P.B. Dirks Tumour-initiating cells: challenges and opportunities for anticancer drug discovery Nat. Rev. Drug Discov. 8 2009 806 823
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 806-823
-
-
Zhou, B.B.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
38
-
-
16844368698
-
Tumour stem cells and drug resistance
-
M. Dean, T. Fojo, and S. Bates Tumour stem cells and drug resistance Nat. Rev. Cancer 5 2005 275 284
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
39
-
-
79952370202
-
The cancer stem cell: Premises, promises and challenges
-
H. Clevers The cancer stem cell: premises, promises and challenges Nat. Med. 17 2011 313 319
-
(2011)
Nat. Med.
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
41
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
T. Lapidot, C. Sirard, J. Vormoor, B. Murdoch, T. Hoang, J. Caceres-Cortes, M. Minden, B. Paterson, M.A. Caligiuri, and J.E. Dick A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Nature 367 1994 645 648
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
42
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
D. Bonnet, and J.E. Dick Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat. Med. 3 1997 730 737
-
(1997)
Nat. Med.
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
43
-
-
84872600554
-
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
-
S. Schwitalla, A.A. Fingerle, P. Cammareri, T. Nebelsiek, S.I. Goktuna, P.K. Ziegler, O. Canli, J. Heijmans, D.J. Huels, G. Moreaux, R.A. Rupec, M. Gerhard, R. Schmid, N. Barker, H. Clevers, R. Lang, J. Neumann, T. Kirchner, M.M. Taketo, G.R. van den Brink, O.J. Sansom, M.C. Arkan, and F.R. Greten Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties Cell 152 2013 25 38
-
(2013)
Cell
, vol.152
, pp. 25-38
-
-
Schwitalla, S.1
Fingerle, A.A.2
Cammareri, P.3
Nebelsiek, T.4
Goktuna, S.I.5
Ziegler, P.K.6
Canli, O.7
Heijmans, J.8
Huels, D.J.9
Moreaux, G.10
Rupec, R.A.11
Gerhard, M.12
Schmid, R.13
Barker, N.14
Clevers, H.15
Lang, R.16
Neumann, J.17
Kirchner, T.18
Taketo, M.M.19
Van Den Brink, G.R.20
Sansom, O.J.21
Arkan, M.C.22
Greten, F.R.23
more..
-
44
-
-
84887619426
-
Dedifferentiation of committed epithelial cells into stem cells in vivo
-
P.R. Tata, H. Mou, A. Pardo-Saganta, R. Zhao, M. Prabhu, B.M. Law, V. Vinarsky, J.L. Cho, S. Breton, A. Sahay, B.D. Medoff, and J. Rajagopal Dedifferentiation of committed epithelial cells into stem cells in vivo Nature 503 2013 218 223
-
(2013)
Nature
, vol.503
, pp. 218-223
-
-
Tata, P.R.1
Mou, H.2
Pardo-Saganta, A.3
Zhao, R.4
Prabhu, M.5
Law, B.M.6
Vinarsky, V.7
Cho, J.L.8
Breton, S.9
Sahay, A.10
Medoff, B.D.11
Rajagopal, J.12
-
45
-
-
84886399680
-
Regulation of p53 is critical for vertebrate limb regeneration
-
M.H. Yun, P.B. Gates, and J.P. Brockes Regulation of p53 is critical for vertebrate limb regeneration Proc. Natl. Acad. Sci. USA 110 2013 17392 17397
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 17392-17397
-
-
Yun, M.H.1
Gates, P.B.2
Brockes, J.P.3
-
46
-
-
84871456408
-
Induced pluripotency and oncogenic transformation are related processes
-
J.W. Riggs, B.L. Barrilleaux, N. Varlakhanova, K.M. Bush, V. Chan, and P.S. Knoepfler Induced pluripotency and oncogenic transformation are related processes Stem Cells Dev. 22 2013 37 50
-
(2013)
Stem Cells Dev.
, vol.22
, pp. 37-50
-
-
Riggs, J.W.1
Barrilleaux, B.L.2
Varlakhanova, N.3
Bush, K.M.4
Chan, V.5
Knoepfler, P.S.6
-
47
-
-
0022390692
-
P53 cellular tumor antigen: Analysis of mRNA levels in normal adult tissues, embryos, and tumors
-
A. Rogel, M. Popliker, C.G. Webb, and M. Oren p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors Mol. Cell. Biol. 5 1985 2851 2855
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 2851-2855
-
-
Rogel, A.1
Popliker, M.2
Webb, C.G.3
Oren, M.4
-
48
-
-
0019164934
-
An embryo protein induced by SV40 virus transformation of mouse cells
-
P.T. Mora, K. Chandrasekaran, and V.W. McFarland An embryo protein induced by SV40 virus transformation of mouse cells Nature 288 1980 722 724
-
(1980)
Nature
, vol.288
, pp. 722-724
-
-
Mora, P.T.1
Chandrasekaran, K.2
McFarland, V.W.3
-
49
-
-
0019792349
-
Quantitation and characterization of a species-specific and embryo stage-dependent 55-kilodalton phosphoprotein also present in cells transformed by simian virus 40
-
K. Chandrasekaran, V.W. McFarland, D.T. Simmons, M. Dziadek, E.G. Gurney, and P.T. Mora Quantitation and characterization of a species-specific and embryo stage-dependent 55-kilodalton phosphoprotein also present in cells transformed by simian virus 40 Proc. Natl. Acad. Sci. USA 78 1981 6953 6957
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 6953-6957
-
-
Chandrasekaran, K.1
McFarland, V.W.2
Simmons, D.T.3
Dziadek, M.4
Gurney, E.G.5
Mora, P.T.6
-
51
-
-
0030663519
-
Regulation of ES cell differentiation by functional and conformational modulation of p53
-
K. Sabapathy, M. Klemm, R. Jaenisch, and E.F. Wagner Regulation of ES cell differentiation by functional and conformational modulation of p53 EMBO J. 16 1997 6217 6229
-
(1997)
EMBO J.
, vol.16
, pp. 6217-6229
-
-
Sabapathy, K.1
Klemm, M.2
Jaenisch, R.3
Wagner, E.F.4
-
52
-
-
39749087530
-
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
-
M.K. Han, E.K. Song, Y. Guo, X. Ou, C. Mantel, and H.E. Broxmeyer SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization Cell Stem Cell 2 2008 241 251
-
(2008)
Cell Stem Cell
, vol.2
, pp. 241-251
-
-
Han, M.K.1
Song, E.K.2
Guo, Y.3
Ou, X.4
Mantel, C.5
Broxmeyer, H.E.6
-
53
-
-
44249101836
-
P53 is required for etoposide-induced apoptosis of human embryonic stem cells
-
C. Grandela, M.F. Pera, S.M. Grimmond, G. Kolle, and E.J. Wolvetang p53 is required for etoposide-induced apoptosis of human embryonic stem cells Stem Cell Res. 1 2007 116 128
-
(2007)
Stem Cell Res.
, vol.1
, pp. 116-128
-
-
Grandela, C.1
Pera, M.F.2
Grimmond, S.M.3
Kolle, G.4
Wolvetang, E.J.5
-
54
-
-
34247172579
-
Regulation of apoptosis and differentiation by p53 in human embryonic stem cells
-
H. Qin, T. Yu, T. Qing, Y. Liu, Y. Zhao, J. Cai, J. Li, Z. Song, X. Qu, P. Zhou, J. Wu, M. Ding, and H. Deng Regulation of apoptosis and differentiation by p53 in human embryonic stem cells J. Biol. Chem. 282 2007 5842 5852
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 5842-5852
-
-
Qin, H.1
Yu, T.2
Qing, T.3
Liu, Y.4
Zhao, Y.5
Cai, J.6
Li, J.7
Song, Z.8
Qu, X.9
Zhou, P.10
Wu, J.11
Ding, M.12
Deng, H.13
-
55
-
-
0032576768
-
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
-
M.I. Aladjem, B.T. Spike, L.W. Rodewald, T.J. Hope, M. Klemm, R. Jaenisch, and G.M. Wahl ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage Curr. Biol. 8 1998 145 155
-
(1998)
Curr. Biol.
, vol.8
, pp. 145-155
-
-
Aladjem, M.I.1
Spike, B.T.2
Rodewald, L.W.3
Hope, T.J.4
Klemm, M.5
Jaenisch, R.6
Wahl, G.M.7
-
56
-
-
84857483281
-
P53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells
-
A.K. Jain, K. Allton, M. Iacovino, E. Mahen, R.J. Milczarek, T.P. Zwaka, M. Kyba, and M.C. Barton p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells PLoS Biol. 10 2012 e1001268
-
(2012)
PLoS Biol.
, vol.10
, pp. 1001268
-
-
Jain, A.K.1
Allton, K.2
Iacovino, M.3
Mahen, E.4
Milczarek, R.J.5
Zwaka, T.P.6
Kyba, M.7
Barton, M.C.8
-
57
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
L.A. Donehower, M. Harvey, B.L. Slagle, M.J. McArthur, C.A. Montgomery Jr.; J.S. Butel, and A. Bradley Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours Nature 356 1992 215 221
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery, Jr.C.A.5
Butel, J.S.6
Bradley, A.7
-
58
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
K. Mitsui, Y. Tokuzawa, H. Itoh, K. Segawa, M. Murakami, K. Takahashi, M. Maruyama, M. Maeda, and S. Yamanaka The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells Cell 113 2003 631 642
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
Takahashi, K.6
Maruyama, M.7
Maeda, M.8
Yamanaka, S.9
-
59
-
-
33645381936
-
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
-
Y.H. Loh, Q. Wu, J.L. Chew, V.B. Vega, W. Zhang, X. Chen, G. Bourque, J. George, B. Leong, J. Liu, K.Y. Wong, K.W. Sung, C.W. Lee, X.D. Zhao, K.P. Chiu, L. Lipovich, V.A. Kuznetsov, P. Robson, L.W. Stanton, C.L. Wei, Y. Ruan, B. Lim, and H.H. Ng The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells Nat. Genet. 38 2006 431 440
-
(2006)
Nat. Genet.
, vol.38
, pp. 431-440
-
-
Loh, Y.H.1
Wu, Q.2
Chew, J.L.3
Vega, V.B.4
Zhang, W.5
Chen, X.6
Bourque, G.7
George, J.8
Leong, B.9
Liu, J.10
Wong, K.Y.11
Sung, K.W.12
Lee, C.W.13
Zhao, X.D.14
Chiu, K.P.15
Lipovich, L.16
Kuznetsov, V.A.17
Robson, P.18
Stanton, L.W.19
Wei, C.L.20
Ruan, Y.21
Lim, B.22
Ng, H.H.23
more..
-
60
-
-
84891823754
-
Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation
-
Z.N. Zhang, S.K. Chung, Z. Xu, and Y. Xu Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation Stem Cells 32 2014 157 165
-
(2014)
Stem Cells
, vol.32
, pp. 157-165
-
-
Zhang, Z.N.1
Chung, S.K.2
Xu, Z.3
Xu, Y.4
-
61
-
-
84864631288
-
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling
-
D.F. Lee, J. Su, Y.S. Ang, X. Carvajal-Vergara, S. Mulero-Navarro, C.F. Pereira, J. Gingold, H.L. Wang, R. Zhao, A. Sevilla, H. Darr, A.J. Williamson, B. Chang, X. Niu, F. Aguilo, E.R. Flores, Y.P. Sher, M.C. Hung, A.D. Whetton, B.D. Gelb, K.A. Moore, H.W. Snoeck, A. Ma'ayan, C. Schaniel, and I.R. Lemischka Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling Cell Stem Cell 11 2012 179 194
-
(2012)
Cell Stem Cell
, vol.11
, pp. 179-194
-
-
Lee, D.F.1
Su, J.2
Ang, Y.S.3
Carvajal-Vergara, X.4
Mulero-Navarro, S.5
Pereira, C.F.6
Gingold, J.7
Wang, H.L.8
Zhao, R.9
Sevilla, A.10
Darr, H.11
Williamson, A.J.12
Chang, B.13
Niu, X.14
Aguilo, F.15
Flores, E.R.16
Sher, Y.P.17
Hung, M.C.18
Whetton, A.D.19
Gelb, B.D.20
Moore, K.A.21
Snoeck, H.W.22
Ma'Ayan, A.23
Schaniel, C.24
Lemischka, I.R.25
more..
-
62
-
-
84891775193
-
Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells
-
K.C. Akdemir, A.K. Jain, K. Allton, B. Aronow, X. Xu, A.J. Cooney, W. Li, and M.C. Barton Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells Nucleic Acids Res. 42 2014 205 223
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 205-223
-
-
Akdemir, K.C.1
Jain, A.K.2
Allton, K.3
Aronow, B.4
Xu, X.5
Cooney, A.J.6
Li, W.7
Barton, M.C.8
-
63
-
-
77954758157
-
Polycomb group protein-mediated repression of transcription
-
L. Morey, and K. Helin Polycomb group protein-mediated repression of transcription Trends Biochem. Sci. 35 2010 323 332
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 323-332
-
-
Morey, L.1
Helin, K.2
-
64
-
-
0041689966
-
Targeted deletion reveals an essential function for the telomere length regulator Trf1
-
J. Karlseder, L. Kachatrian, H. Takai, K. Mercer, S. Hingorani, T. Jacks, and T. de Lange Targeted deletion reveals an essential function for the telomere length regulator Trf1 Mol. Cell. Biol. 23 2003 6533 6541
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6533-6541
-
-
Karlseder, J.1
Kachatrian, L.2
Takai, H.3
Mercer, K.4
Hingorani, S.5
Jacks, T.6
De Lange, T.7
-
65
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Y. Zhao, X. Yin, H. Qin, F. Zhu, H. Liu, W. Yang, Q. Zhang, C. Xiang, P. Hou, Z. Song, Y. Liu, J. Yong, P. Zhang, J. Cai, M. Liu, H. Li, Y. Li, X. Qu, K. Cui, W. Zhang, T. Xiang, Y. Wu, C. Liu, C. Yu, K. Yuan, J. Lou, M. Ding, and H. Deng Two supporting factors greatly improve the efficiency of human iPSC generation Cell Stem Cell 3 2008 475 479
-
(2008)
Cell Stem Cell
, vol.3
, pp. 475-479
-
-
Zhao, Y.1
Yin, X.2
Qin, H.3
Zhu, F.4
Liu, H.5
Yang, W.6
Zhang, Q.7
Xiang, C.8
Hou, P.9
Song, Z.10
Liu, Y.11
Yong, J.12
Zhang, P.13
Cai, J.14
Liu, M.15
Li, H.16
Li, Y.17
Qu, X.18
Cui, K.19
Zhang, W.20
Xiang, T.21
Wu, Y.22
Liu, C.23
Yu, C.24
Yuan, K.25
Lou, J.26
Ding, M.27
Deng, H.28
more..
-
66
-
-
70349093119
-
Senescence impairs successful reprogramming to pluripotent stem cells
-
A. Banito, S.T. Rashid, J.C. Acosta, S. Li, C.F. Pereira, I. Geti, S. Pinho, J.C. Silva, V. Azuara, M. Walsh, L. Vallier, and J. Gil Senescence impairs successful reprogramming to pluripotent stem cells Genes Dev. 23 2009 2134 2139
-
(2009)
Genes Dev.
, vol.23
, pp. 2134-2139
-
-
Banito, A.1
Rashid, S.T.2
Acosta, J.C.3
Li, S.4
Pereira, C.F.5
Geti, I.6
Pinho, S.7
Silva, J.C.8
Azuara, V.9
Walsh, M.10
Vallier, L.11
Gil, J.12
-
67
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
H. Hong, K. Takahashi, T. Ichisaka, T. Aoi, O. Kanagawa, M. Nakagawa, K. Okita, and S. Yamanaka Suppression of induced pluripotent stem cell generation by the p53-p21 pathway Nature 460 2009 1132 1135
-
(2009)
Nature
, vol.460
, pp. 1132-1135
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
Aoi, T.4
Kanagawa, O.5
Nakagawa, M.6
Okita, K.7
Yamanaka, S.8
-
68
-
-
69349100455
-
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
-
T. Kawamura, J. Suzuki, Y.V. Wang, S. Menendez, L.B. Morera, A. Raya, G.M. Wahl, and J.C. Belmonte Linking the p53 tumour suppressor pathway to somatic cell reprogramming Nature 460 2009 1140 1144
-
(2009)
Nature
, vol.460
, pp. 1140-1144
-
-
Kawamura, T.1
Suzuki, J.2
Wang, Y.V.3
Menendez, S.4
Morera, L.B.5
Raya, A.6
Wahl, G.M.7
Belmonte, J.C.8
-
69
-
-
69349103956
-
The Ink4/Arf locus is a barrier for iPS cell reprogramming
-
H. Li, M. Collado, A. Villasante, K. Strati, S. Ortega, M. Canamero, M.A. Blasco, and M. Serrano The Ink4/Arf locus is a barrier for iPS cell reprogramming Nature 460 2009 1136 1139
-
(2009)
Nature
, vol.460
, pp. 1136-1139
-
-
Li, H.1
Collado, M.2
Villasante, A.3
Strati, K.4
Ortega, S.5
Canamero, M.6
Blasco, M.A.7
Serrano, M.8
-
70
-
-
69349094006
-
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
-
R.M. Marion, K. Strati, H. Li, M. Murga, R. Blanco, S. Ortega, O. Fernandez-Capetillo, M. Serrano, and M.A. Blasco A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity Nature 460 2009 1149 1153
-
(2009)
Nature
, vol.460
, pp. 1149-1153
-
-
Marion, R.M.1
Strati, K.2
Li, H.3
Murga, M.4
Blanco, R.5
Ortega, S.6
Fernandez-Capetillo, O.7
Serrano, M.8
Blasco, M.A.9
-
71
-
-
69349098273
-
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
-
J. Utikal, J.M. Polo, M. Stadtfeld, N. Maherali, W. Kulalert, R.M. Walsh, A. Khalil, J.G. Rheinwald, and K. Hochedlinger Immortalization eliminates a roadblock during cellular reprogramming into iPS cells Nature 460 2009 1145 1148
-
(2009)
Nature
, vol.460
, pp. 1145-1148
-
-
Utikal, J.1
Polo, J.M.2
Stadtfeld, M.3
Maherali, N.4
Kulalert, W.5
Walsh, R.M.6
Khalil, A.7
Rheinwald, J.G.8
Hochedlinger, K.9
-
72
-
-
73949130140
-
Effective generation of iPS cells from CD34(+) cord blood cells by inhibition of p53
-
C. Takenaka, N. Nishishita, N. Takada, L.M. Jakt, and S. Kawamata Effective generation of iPS cells from CD34(+) cord blood cells by inhibition of p53 Exp. Hematol. 38 2010 154 162
-
(2010)
Exp. Hematol.
, vol.38
, pp. 154-162
-
-
Takenaka, C.1
Nishishita, N.2
Takada, N.3
Jakt, L.M.4
Kawamata, S.5
-
73
-
-
77957748239
-
Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells
-
R. Sarig, N. Rivlin, R. Brosh, C. Bornstein, I. Kamer, O. Ezra, A. Molchadsky, N. Goldfinger, O. Brenner, and V. Rotter Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells J. Exp. Med. 207 2010 2127 2140
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2127-2140
-
-
Sarig, R.1
Rivlin, N.2
Brosh, R.3
Bornstein, C.4
Kamer, I.5
Ezra, O.6
Molchadsky, A.7
Goldfinger, N.8
Brenner, O.9
Rotter, V.10
-
74
-
-
77957733786
-
P53 connects tumorigenesis and reprogramming to pluripotency
-
N. Tapia, and H.R. Scholer p53 connects tumorigenesis and reprogramming to pluripotency J. Exp. Med. 207 2010 2045 2048
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2045-2048
-
-
Tapia, N.1
Scholer, H.R.2
-
75
-
-
71449109765
-
Direct cell reprogramming is a stochastic process amenable to acceleration
-
J. Hanna, K. Saha, B. Pando, J. van Zon, C.J. Lengner, M.P. Creyghton, A. van Oudenaarden, and R. Jaenisch Direct cell reprogramming is a stochastic process amenable to acceleration Nature 462 2009 595 601
-
(2009)
Nature
, vol.462
, pp. 595-601
-
-
Hanna, J.1
Saha, K.2
Pando, B.3
Van Zon, J.4
Lengner, C.J.5
Creyghton, M.P.6
Van Oudenaarden, A.7
Jaenisch, R.8
-
76
-
-
84862843347
-
P53-facilitated miR-199a-3p regulates somatic cell reprogramming
-
J. Wang, Q. He, C. Han, H. Gu, L. Jin, Q. Li, Y. Mei, and M. Wu p53-facilitated miR-199a-3p regulates somatic cell reprogramming Stem Cells 30 2012 1405 1413
-
(2012)
Stem Cells
, vol.30
, pp. 1405-1413
-
-
Wang, J.1
He, Q.2
Han, C.3
Gu, H.4
Jin, L.5
Li, Q.6
Mei, Y.7
Wu, M.8
-
77
-
-
84880837087
-
The p53-PUMA axis suppresses iPSC generation
-
Y. Li, H. Feng, H. Gu, D.W. Lewis, Y. Yuan, L. Zhang, H. Yu, P. Zhang, H. Cheng, W. Miao, W. Yuan, S.Y. Cheng, S.M. Gollin, and T. Cheng The p53-PUMA axis suppresses iPSC generation Nat. Commun. 4 2013 2174
-
(2013)
Nat. Commun.
, vol.4
, pp. 2174
-
-
Li, Y.1
Feng, H.2
Gu, H.3
Lewis, D.W.4
Yuan, Y.5
Zhang, L.6
Yu, H.7
Zhang, P.8
Cheng, H.9
Miao, W.10
Yuan, W.11
Cheng, S.Y.12
Gollin, S.M.13
Cheng, T.14
-
78
-
-
58249085824
-
Role of the murine reprogramming factors in the induction of pluripotency
-
R. Sridharan, J. Tchieu, M.J. Mason, R. Yachechko, E. Kuoy, S. Horvath, Q. Zhou, and K. Plath Role of the murine reprogramming factors in the induction of pluripotency Cell 136 2009 364 377
-
(2009)
Cell
, vol.136
, pp. 364-377
-
-
Sridharan, R.1
Tchieu, J.2
Mason, M.J.3
Yachechko, R.4
Kuoy, E.5
Horvath, S.6
Zhou, Q.7
Plath, K.8
-
79
-
-
84868224979
-
Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation
-
L. Yi, C. Lu, W. Hu, Y. Sun, and A.J. Levine Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation Cancer Res. 72 2012 5635 5645
-
(2012)
Cancer Res.
, vol.72
, pp. 5635-5645
-
-
Yi, L.1
Lu, C.2
Hu, W.3
Sun, Y.4
Levine, A.J.5
-
80
-
-
84875805512
-
Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state
-
F. Gonzalez, D. Georgieva, F. Vanoli, Z.D. Shi, M. Stadtfeld, T. Ludwig, M. Jasin, and D. Huangfu Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state Cell Rep. 3 2013 651 660
-
(2013)
Cell Rep.
, vol.3
, pp. 651-660
-
-
Gonzalez, F.1
Georgieva, D.2
Vanoli, F.3
Shi, Z.D.4
Stadtfeld, M.5
Ludwig, T.6
Jasin, M.7
Huangfu, D.8
-
81
-
-
77950265945
-
Linking functional decline of telomeres, mitochondria and stem cells during ageing
-
E. Sahin, and R.A. Depinho Linking functional decline of telomeres, mitochondria and stem cells during ageing Nature 464 2010 520 528
-
(2010)
Nature
, vol.464
, pp. 520-528
-
-
Sahin, E.1
Depinho, R.A.2
-
83
-
-
0033515827
-
Multilineage potenital of adult human mesenchymal stem cells
-
M.F. Pittenger, A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, J.D. Mosca, M.A. Moorman, D.W. Simonetti, S. Craig, and D.R. Marshak Multilineage potenital of adult human mesenchymal stem cells Science 284 1999 143 147
-
(1999)
Science
, vol.284
, pp. 143-147
-
-
Pittenger, M.F.1
Mackay, A.M.2
Beck, S.C.3
Jaiswal, R.K.4
Douglas, R.5
Mosca, J.D.6
Moorman, M.A.7
Simonetti, D.W.8
Craig, S.9
Marshak, D.R.10
-
84
-
-
33644879150
-
Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling
-
C.J. Lengner, H.A. Steinman, J. Gagnon, T.W. Smith, J.E. Henderson, B.E. Kream, G.S. Stein, J.B. Lian, and S.N. Jones Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling J. Cell Biol. 172 2006 909 921
-
(2006)
J. Cell Biol.
, vol.172
, pp. 909-921
-
-
Lengner, C.J.1
Steinman, H.A.2
Gagnon, J.3
Smith, T.W.4
Henderson, J.E.5
Kream, B.E.6
Stein, G.S.7
Lian, J.B.8
Jones, S.N.9
-
85
-
-
70449521174
-
P53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells
-
A. Armesilla-Diaz, G. Elvira, and A. Silva p53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells Exp. Cell Res. 315 2009 3598 3610
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 3598-3610
-
-
Armesilla-Diaz, A.1
Elvira, G.2
Silva, A.3
-
86
-
-
77950645030
-
Age-related molecular genetic changes of murine bone marrow mesenchymal stem cells
-
A. Wilson, L.A. Shehadeh, H. Yu, and K.A. Webster Age-related molecular genetic changes of murine bone marrow mesenchymal stem cells BMC Genomics 11 2010 229
-
(2010)
BMC Genomics
, vol.11
, pp. 229
-
-
Wilson, A.1
Shehadeh, L.A.2
Yu, H.3
Webster, K.A.4
-
87
-
-
36348999909
-
Spontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: A model of age-related tumorigenesis in mice
-
H. Li, X. Fan, R.C. Kovi, Y. Jo, B. Moquin, R. Konz, C. Stoicov, E. Kurt-Jones, S.R. Grossman, S. Lyle, A.B. Rogers, M. Montrose, and J. Houghton Spontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: a model of age-related tumorigenesis in mice Cancer Res. 67 2007 10889 10898
-
(2007)
Cancer Res.
, vol.67
, pp. 10889-10898
-
-
Li, H.1
Fan, X.2
Kovi, R.C.3
Jo, Y.4
Moquin, B.5
Konz, R.6
Stoicov, C.7
Kurt-Jones, E.8
Grossman, S.R.9
Lyle, S.10
Rogers, A.B.11
Montrose, M.12
Houghton, J.13
-
88
-
-
84905115663
-
P53 regulates mesenchymal stem cell-mediated tumor suppression in a tumor microenvironment through immune modulation
-
Y. Huang, P. Yu, W. Li, G. Ren, A.I. Roberts, W. Cao, X. Zhang, J. Su, X. Chen, Q. Chen, P. Shou, C. Xu, L. Du, L. Lin, N. Xie, L. Zhang, Y. Wang, and Y. Shi p53 regulates mesenchymal stem cell-mediated tumor suppression in a tumor microenvironment through immune modulation Oncogene 2013
-
(2013)
Oncogene
-
-
Huang, Y.1
Yu, P.2
Li, W.3
Ren, G.4
Roberts, A.I.5
Cao, W.6
Zhang, X.7
Su, J.8
Chen, X.9
Chen, Q.10
Shou, P.11
Xu, C.12
Du, L.13
Lin, L.14
Xie, N.15
Zhang, L.16
Wang, Y.17
Shi, Y.18
-
89
-
-
79953000341
-
Concise review: Mesenchymal tumors: When stem cells go mad
-
A.B. Mohseny, and P.C. Hogendoorn Concise review: mesenchymal tumors: when stem cells go mad Stem Cells 29 2011 397 403
-
(2011)
Stem Cells
, vol.29
, pp. 397-403
-
-
Mohseny, A.B.1
Hogendoorn, P.C.2
-
90
-
-
84855477391
-
Modeling sarcomagenesis using multipotent mesenchymal stem cells
-
R. Rodriguez, R. Rubio, and P. Menendez Modeling sarcomagenesis using multipotent mesenchymal stem cells Cell Res. 22 2012 62 77
-
(2012)
Cell Res.
, vol.22
, pp. 62-77
-
-
Rodriguez, R.1
Rubio, R.2
Menendez, P.3
-
91
-
-
65549125914
-
Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells
-
R. Rodriguez, R. Rubio, M. Masip, P. Catalina, A. Nieto, T. de la Cueva, M. Arriero, N. San Martin, E. de la Cueva, D. Balomenos, P. Menendez, and J. Garcia-Castro Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells Neoplasia 11 2009 397 407
-
(2009)
Neoplasia
, vol.11
, pp. 397-407
-
-
Rodriguez, R.1
Rubio, R.2
Masip, M.3
Catalina, P.4
Nieto, A.5
De La Cueva, T.6
Arriero, M.7
San Martin, N.8
De La Cueva, E.9
Balomenos, D.10
Menendez, P.11
Garcia-Castro, J.12
-
92
-
-
77952804351
-
Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo
-
R. Rubio, J. Garcia-Castro, I. Gutierrez-Aranda, J. Paramio, M. Santos, P. Catalina, P.E. Leone, P. Menendez, and R. Rodriguez Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo Cancer Res. 70 2010 4185 4194
-
(2010)
Cancer Res.
, vol.70
, pp. 4185-4194
-
-
Rubio, R.1
Garcia-Castro, J.2
Gutierrez-Aranda, I.3
Paramio, J.4
Santos, M.5
Catalina, P.6
Leone, P.E.7
Menendez, P.8
Rodriguez, R.9
-
93
-
-
84885573865
-
The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development
-
R. Rubio, I. Gutierrez-Aranda, A.I. Saez-Castillo, A. Labarga, M. Rosu-Myles, S. Gonzalez-Garcia, M.L. Toribio, P. Menendez, and R. Rodriguez The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development Oncogene 32 2013 4970 4980
-
(2013)
Oncogene
, vol.32
, pp. 4970-4980
-
-
Rubio, R.1
Gutierrez-Aranda, I.2
Saez-Castillo, A.I.3
Labarga, A.4
Rosu-Myles, M.5
Gonzalez-Garcia, S.6
Toribio, M.L.7
Menendez, P.8
Rodriguez, R.9
-
94
-
-
57849109837
-
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
-
S. Alcantara Llaguno, J. Chen, C.H. Kwon, E.L. Jackson, Y. Li, D.K. Burns, A. Alvarez-Buylla, and L.F. Parada Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model Cancer Cell 15 2009 45 56
-
(2009)
Cancer Cell
, vol.15
, pp. 45-56
-
-
Alcantara Llaguno, S.1
Chen, J.2
Kwon, C.H.3
Jackson, E.L.4
Li, Y.5
Burns, D.K.6
Alvarez-Buylla, A.7
Parada, L.F.8
-
95
-
-
0029764225
-
Loss of heterozygosity and tumor suppressor gene mutations in chondrosarcomas
-
T. Yamaguchi, J. Toguchida, B. Wadayama, H. Kanoe, T. Nakayama, K. Ishizaki, M. Ikenaga, Y. Kotoura, and M.S. Sasaki Loss of heterozygosity and tumor suppressor gene mutations in chondrosarcomas Anticancer Res. 16 1996 2009 2015
-
(1996)
Anticancer Res.
, vol.16
, pp. 2009-2015
-
-
Yamaguchi, T.1
Toguchida, J.2
Wadayama, B.3
Kanoe, H.4
Nakayama, T.5
Ishizaki, K.6
Ikenaga, M.7
Kotoura, Y.8
Sasaki, M.S.9
-
96
-
-
0027203921
-
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
-
C.J. Kemp, L.A. Donehower, A. Bradley, and A. Balmain Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors Cell 74 1993 813 822
-
(1993)
Cell
, vol.74
, pp. 813-822
-
-
Kemp, C.J.1
Donehower, L.A.2
Bradley, A.3
Balmain, A.4
-
97
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
J.A. Fagin, K. Matsuo, A. Karmakar, D.L. Chen, S.H. Tang, and H.P. Koeffler High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas J. Clin. Investig. 91 1993 179 184
-
(1993)
J. Clin. Investig.
, vol.91
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Chen, D.L.4
Tang, S.H.5
Koeffler, H.P.6
-
98
-
-
0027215123
-
Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland
-
R. Donghi, A. Longoni, S. Pilotti, P. Michieli, G. Della Porta, and M.A. Pierotti Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland J. Clin. Investig. 91 1993 1753 1760
-
(1993)
J. Clin. Investig.
, vol.91
, pp. 1753-1760
-
-
Donghi, R.1
Longoni, A.2
Pilotti, S.3
Michieli, P.4
Della Porta, G.5
Pierotti, M.A.6
-
99
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
I. Ben-Porath, M.W. Thomson, V.J. Carey, R. Ge, G.W. Bell, A. Regev, and R.A. Weinberg An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors Nat. Genet. 40 2008 499 507
-
(2008)
Nat. Genet.
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
Weinberg, R.A.7
-
100
-
-
78651100119
-
Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures
-
H. Mizuno, B.T. Spike, G.M. Wahl, and A.J. Levine Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures Proc. Natl. Acad. Sci. USA 107 2010 22745 22750
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 22745-22750
-
-
Mizuno, H.1
Spike, B.T.2
Wahl, G.M.3
Levine, A.J.4
-
101
-
-
84855484465
-
Molecular classification of prostate cancer using curated expression signatures
-
E.K. Markert, H. Mizuno, A. Vazquez, and A.J. Levine Molecular classification of prostate cancer using curated expression signatures Proc. Natl. Acad. Sci. USA 108 2011 21276 21281
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 21276-21281
-
-
Markert, E.K.1
Mizuno, H.2
Vazquez, A.3
Levine, A.J.4
-
102
-
-
46149089421
-
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression
-
S. Godar, T.A. Ince, G.W. Bell, D. Feldser, J.L. Donaher, J. Bergh, A. Liu, K. Miu, R.S. Watnick, F. Reinhardt, S.S. McAllister, T. Jacks, and R.A. Weinberg Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression Cell 134 2008 62 73
-
(2008)
Cell
, vol.134
, pp. 62-73
-
-
Godar, S.1
Ince, T.A.2
Bell, G.W.3
Feldser, D.4
Donaher, J.L.5
Bergh, J.6
Liu, A.7
Miu, K.8
Watnick, R.S.9
Reinhardt, F.10
McAllister, S.S.11
Jacks, T.12
Weinberg, R.A.13
-
103
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
D. Malkin, F.P. Li, L.C. Strong, J.F. Fraumeni Jr.; C.E. Nelson, D.H. Kim, J. Kassel, M.A. Gryka, F.Z. Bischoff, and M.A. Tainsky et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms Science 250 1990 1233 1238
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni, Jr.J.F.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
-
104
-
-
13644260907
-
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome
-
G.A. Lang, T. Iwakuma, Y.A. Suh, G. Liu, V.A. Rao, J.M. Parant, Y.A. Valentin-Vega, T. Terzian, L.C. Caldwell, L.C. Strong, A.K. El-Naggar, and G. Lozano Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome Cell 119 2004 861 872
-
(2004)
Cell
, vol.119
, pp. 861-872
-
-
Lang, G.A.1
Iwakuma, T.2
Suh, Y.A.3
Liu, G.4
Rao, V.A.5
Parant, J.M.6
Valentin-Vega, Y.A.7
Terzian, T.8
Caldwell, L.C.9
Strong, L.C.10
El-Naggar, A.K.11
Lozano, G.12
-
105
-
-
0030957152
-
Li-Fraumeni syndrome - A molecular and clinical review
-
J.M. Varley, D.G. Evans, and J.M. Birch Li-Fraumeni syndrome - A molecular and clinical review Br. J. Cancer 76 1997 1 14
-
(1997)
Br. J. Cancer
, vol.76
, pp. 1-14
-
-
Varley, J.M.1
Evans, D.G.2
Birch, J.M.3
-
106
-
-
0035049323
-
Methylation in the p53 promoter is a supplementary route to breast carcinogenesis: Correlation between CpG methylation in the p53 promoter and the mutation of the p53 gene in the progression from ductal carcinoma in situ to invasive ductal carcinoma
-
J.H. Kang, S.J. Kim, D.Y. Noh, I.A. Park, K.J. Choe, O.J. Yoo, and H.S. Kang Methylation in the p53 promoter is a supplementary route to breast carcinogenesis: correlation between CpG methylation in the p53 promoter and the mutation of the p53 gene in the progression from ductal carcinoma in situ to invasive ductal carcinoma Lab. Invest. 81 2001 573 579
-
(2001)
Lab. Invest.
, vol.81
, pp. 573-579
-
-
Kang, J.H.1
Kim, S.J.2
Noh, D.Y.3
Park, I.A.4
Choe, K.J.5
Yoo, O.J.6
Kang, H.S.7
-
107
-
-
17144463251
-
Abnormal expression of MDM2 in prostate carcinoma
-
K.R. Leite, M.F. Franco, M. Srougi, L.J. Nesrallah, A. Nesrallah, R.G. Bevilacqua, E. Darini, C.M. Carvalho, M.I. Meirelles, I. Santana, and L.H. Camara-Lopes Abnormal expression of MDM2 in prostate carcinoma Mod. Pathol. 14 2001 428 436
-
(2001)
Mod. Pathol.
, vol.14
, pp. 428-436
-
-
Leite, K.R.1
Franco, M.F.2
Srougi, M.3
Nesrallah, L.J.4
Nesrallah, A.5
Bevilacqua, R.G.6
Darini, E.7
Carvalho, C.M.8
Meirelles, M.I.9
Santana, I.10
Camara-Lopes, L.H.11
-
108
-
-
33749128524
-
Unique substitution of CHEK2 and TP53 mutations implicated in primary prostate tumors and cancer cell lines
-
L. Zheng, F. Wang, C. Qian, R.M. Neumann, J.C. Cheville, D.J. Tindall, and W. Liu Unique substitution of CHEK2 and TP53 mutations implicated in primary prostate tumors and cancer cell lines Hum. Mutat. 27 2006 1062 1063
-
(2006)
Hum. Mutat.
, vol.27
, pp. 1062-1063
-
-
Zheng, L.1
Wang, F.2
Qian, C.3
Neumann, R.M.4
Cheville, J.C.5
Tindall, D.J.6
Liu, W.7
-
109
-
-
80053039210
-
Mutations in the p53 tumor suppressor gene: Important milestones at the various steps of tumorigenesis
-
N. Rivlin, R. Brosh, M. Oren, and V. Rotter Mutations in the p53 tumor suppressor gene: important milestones at the various steps of tumorigenesis Genes Cancer 2 2011 466 474
-
(2011)
Genes Cancer
, vol.2
, pp. 466-474
-
-
Rivlin, N.1
Brosh, R.2
Oren, M.3
Rotter, V.4
-
110
-
-
77950239571
-
P53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways
-
Y. Buganim, H. Solomon, Y. Rais, D. Kistner, I. Nachmany, M. Brait, S. Madar, I. Goldstein, E. Kalo, N. Adam, M. Gordin, N. Rivlin, I. Kogan, R. Brosh, G. Sefadia-Elad, N. Goldfinger, D. Sidransky, Y. Kloog, and V. Rotter p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways Cancer Res. 70 2010 2274 2284
-
(2010)
Cancer Res.
, vol.70
, pp. 2274-2284
-
-
Buganim, Y.1
Solomon, H.2
Rais, Y.3
Kistner, D.4
Nachmany, I.5
Brait, M.6
Madar, S.7
Goldstein, I.8
Kalo, E.9
Adam, N.10
Gordin, M.11
Rivlin, N.12
Kogan, I.13
Brosh, R.14
Sefadia-Elad, G.15
Goldfinger, N.16
Sidransky, D.17
Kloog, Y.18
Rotter, V.19
-
111
-
-
78650027929
-
Haplo-insufficiency: A driving force in cancer
-
A.H. Berger, and P.P. Pandolfi Haplo-insufficiency: a driving force in cancer J. Pathol. 223 2011 137 146
-
(2011)
J. Pathol.
, vol.223
, pp. 137-146
-
-
Berger, A.H.1
Pandolfi, P.P.2
-
112
-
-
34248379012
-
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
-
A. Petitjean, E. Mathe, S. Kato, C. Ishioka, S.V. Tavtigian, P. Hainaut, and M. Olivier Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database Hum. Mutat. 28 2007 622 629
-
(2007)
Hum. Mutat.
, vol.28
, pp. 622-629
-
-
Petitjean, A.1
Mathe, E.2
Kato, S.3
Ishioka, C.4
Tavtigian, S.V.5
Hainaut, P.6
Olivier, M.7
-
113
-
-
80053266411
-
Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency
-
R. van Boxtel, R.V. Kuiper, P.W. Toonen, S. van Heesch, R. Hermsen, A. de Bruin, and E. Cuppen Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency Am. J. Pathol. 179 2011 1616 1622
-
(2011)
Am. J. Pathol.
, vol.179
, pp. 1616-1622
-
-
Van Boxtel, R.1
Kuiper, R.V.2
Toonen, P.W.3
Van Heesch, S.4
Hermsen, R.5
De Bruin, A.6
Cuppen, E.7
-
114
-
-
0141819143
-
An age-induced switch to a hyper-recombinational state
-
M.A. McMurray, and D.E. Gottschling An age-induced switch to a hyper-recombinational state Science 301 2003 1908 1911
-
(2003)
Science
, vol.301
, pp. 1908-1911
-
-
McMurray, M.A.1
Gottschling, D.E.2
-
115
-
-
0042027816
-
Treatment of acute promyelocytic leukemia: Strategy toward further increase of cure rate
-
R. Ohno, N. Asou, and K. Ohnishi Treatment of acute promyelocytic leukemia: strategy toward further increase of cure rate Leukemia 17 2003 1454 1463
-
(2003)
Leukemia
, vol.17
, pp. 1454-1463
-
-
Ohno, R.1
Asou, N.2
Ohnishi, K.3
-
116
-
-
0033554684
-
Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group
-
K.K. Matthay, J.G. Villablanca, R.C. Seeger, D.O. Stram, R.E. Harris, N.K. Ramsay, P. Swift, H. Shimada, C.T. Black, G.M. Brodeur, R.B. Gerbing, and C.P. Reynolds Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group N. Engl. J. Med. 341 1999 1165 1173
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 1165-1173
-
-
Matthay, K.K.1
Villablanca, J.G.2
Seeger, R.C.3
Stram, D.O.4
Harris, R.E.5
Ramsay, N.K.6
Swift, P.7
Shimada, H.8
Black, C.T.9
Brodeur, G.M.10
Gerbing, R.B.11
Reynolds, C.P.12
-
117
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
-
S.G. Piccirillo, B.A. Reynolds, N. Zanetti, G. Lamorte, E. Binda, G. Broggi, H. Brem, A. Olivi, F. Dimeco, and A.L. Vescovi Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells Nature 444 2006 761 765
-
(2006)
Nature
, vol.444
, pp. 761-765
-
-
Piccirillo, S.G.1
Reynolds, B.A.2
Zanetti, N.3
Lamorte, G.4
Binda, E.5
Broggi, G.6
Brem, H.7
Olivi, A.8
Dimeco, F.9
Vescovi, A.L.10
-
118
-
-
84877620952
-
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation
-
F. Wang, J. Travins, B. DeLaBarre, V. Penard-Lacronique, S. Schalm, E. Hansen, K. Straley, A. Kernytsky, W. Liu, C. Gliser, H. Yang, S. Gross, E. Artin, V. Saada, E. Mylonas, C. Quivoron, J. Popovici-Muller, J.O. Saunders, F.G. Salituro, S. Yan, S. Murray, W. Wei, Y. Gao, L. Dang, M. Dorsch, S. Agresta, D.P. Schenkein, S.A. Biller, S.M. Su, S. de Botton, and K.E. Yen Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation Science 340 2013 622 626
-
(2013)
Science
, vol.340
, pp. 622-626
-
-
Wang, F.1
Travins, J.2
Delabarre, B.3
Penard-Lacronique, V.4
Schalm, S.5
Hansen, E.6
Straley, K.7
Kernytsky, A.8
Liu, W.9
Gliser, C.10
Yang, H.11
Gross, S.12
Artin, E.13
Saada, V.14
Mylonas, E.15
Quivoron, C.16
Popovici-Muller, J.17
Saunders, J.O.18
Salituro, F.G.19
Yan, S.20
Murray, S.21
Wei, W.22
Gao, Y.23
Dang, L.24
Dorsch, M.25
Agresta, S.26
Schenkein, D.P.27
Biller, S.A.28
Su, S.M.29
De Botton, S.30
Yen, K.E.31
more..
-
119
-
-
84877632013
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
-
D. Rohle, J. Popovici-Muller, N. Palaskas, S. Turcan, C. Grommes, C. Campos, J. Tsoi, O. Clark, B. Oldrini, E. Komisopoulou, K. Kunii, A. Pedraza, S. Schalm, L. Silverman, A. Miller, F. Wang, H. Yang, Y. Chen, A. Kernytsky, M.K. Rosenblum, W. Liu, S.A. Biller, S.M. Su, C.W. Brennan, T.A. Chan, T.G. Graeber, K.E. Yen, and I.K. Mellinghoff An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells Science 340 2013 626 630
-
(2013)
Science
, vol.340
, pp. 626-630
-
-
Rohle, D.1
Popovici-Muller, J.2
Palaskas, N.3
Turcan, S.4
Grommes, C.5
Campos, C.6
Tsoi, J.7
Clark, O.8
Oldrini, B.9
Komisopoulou, E.10
Kunii, K.11
Pedraza, A.12
Schalm, S.13
Silverman, L.14
Miller, A.15
Wang, F.16
Yang, H.17
Chen, Y.18
Kernytsky, A.19
Rosenblum, M.K.20
Liu, W.21
Biller, S.A.22
Su, S.M.23
Brennan, C.W.24
Chan, T.A.25
Graeber, T.G.26
Yen, K.E.27
Mellinghoff, I.K.28
more..
-
120
-
-
84878002317
-
Histone deacetylase inhibitors: An attractive strategy for cancer therapy
-
J. Li, G. Li, and W. Xu Histone deacetylase inhibitors: an attractive strategy for cancer therapy Curr. Med. Chem. 20 2013 1858 1886
-
(2013)
Curr. Med. Chem.
, vol.20
, pp. 1858-1886
-
-
Li, J.1
Li, G.2
Xu, W.3
-
121
-
-
84901335119
-
MicroRNAs as novel regulators of stem cell fate
-
E. Choi, E. Choi, and K.C. Hwang MicroRNAs as novel regulators of stem cell fate World J. Stem Cells 5 2013 172 187
-
(2013)
World J. Stem Cells
, vol.5
, pp. 172-187
-
-
Choi, E.1
Choi, E.2
Hwang, K.C.3
-
122
-
-
77953498262
-
MicroRNA-34a is tumor suppressive in brain tumors and glioma stem cells
-
F. Guessous, Y. Zhang, A. Kofman, A. Catania, Y. Li, D. Schiff, B. Purow, and R. Abounader MicroRNA-34a is tumor suppressive in brain tumors and glioma stem cells Cell Cycle 9 2010 1031 1036
-
(2010)
Cell Cycle
, vol.9
, pp. 1031-1036
-
-
Guessous, F.1
Zhang, Y.2
Kofman, A.3
Catania, A.4
Li, Y.5
Schiff, D.6
Purow, B.7
Abounader, R.8
-
123
-
-
80052632447
-
MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma
-
P. de Antonellis, C. Medaglia, E. Cusanelli, I. Andolfo, L. Liguori, G. De Vita, M. Carotenuto, A. Bello, F. Formiggini, A. Galeone, G. De Rosa, A. Virgilio, I. Scognamiglio, M. Sciro, G. Basso, J.H. Schulte, G. Cinalli, A. Iolascon, and M. Zollo MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma PLoS One 6 2011 e24584
-
(2011)
PLoS One
, vol.6
, pp. 24584
-
-
De Antonellis, P.1
Medaglia, C.2
Cusanelli, E.3
Andolfo, I.4
Liguori, L.5
De Vita, G.6
Carotenuto, M.7
Bello, A.8
Formiggini, F.9
Galeone, A.10
De Rosa, G.11
Virgilio, A.12
Scognamiglio, I.13
Sciro, M.14
Basso, G.15
Schulte, J.H.16
Cinalli, G.17
Iolascon, A.18
Zollo, M.19
-
124
-
-
48949116262
-
MiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
-
J. Silber, D.A. Lim, C. Petritsch, A.I. Persson, A.K. Maunakea, M. Yu, S.R. Vandenberg, D.G. Ginzinger, C.D. James, J.F. Costello, G. Bergers, W.A. Weiss, A. Alvarez-Buylla, and J.G. Hodgson MiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells BMC Med. 6 2008 14
-
(2008)
BMC Med.
, vol.6
, pp. 14
-
-
Silber, J.1
Lim, D.A.2
Petritsch, C.3
Persson, A.I.4
Maunakea, A.K.5
Yu, M.6
Vandenberg, S.R.7
Ginzinger, D.G.8
James, C.D.9
Costello, J.F.10
Bergers, G.11
Weiss, W.A.12
Alvarez-Buylla, A.13
Hodgson, J.G.14
-
125
-
-
0032568329
-
Stable reintroduction of wild-type P53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells
-
D. Lang, S.J. Miknyoczki, L. Huang, and B.A. Ruggeri Stable reintroduction of wild-type P53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells Oncogene 16 1998 1593 1602
-
(1998)
Oncogene
, vol.16
, pp. 1593-1602
-
-
Lang, D.1
Miknyoczki, S.J.2
Huang, L.3
Ruggeri, B.A.4
-
126
-
-
0028337504
-
Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53
-
R. Radinsky, I.J. Fidler, J.E. Price, N. Esumi, R. Tsan, C.M. Petty, C.D. Bucana, and M. Bar-Eli Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53 Oncogene 9 1994 1877 1883
-
(1994)
Oncogene
, vol.9
, pp. 1877-1883
-
-
Radinsky, R.1
Fidler, I.J.2
Price, J.E.3
Esumi, N.4
Tsan, R.5
Petty, C.M.6
Bucana, C.D.7
Bar-Eli, M.8
-
127
-
-
70349123829
-
The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
-
A. Cicalese, G. Bonizzi, C.E. Pasi, M. Faretta, S. Ronzoni, B. Giulini, C. Brisken, S. Minucci, P.P. Di Fiore, and P.G. Pelicci The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells Cell 138 2009 1083 1095
-
(2009)
Cell
, vol.138
, pp. 1083-1095
-
-
Cicalese, A.1
Bonizzi, G.2
Pasi, C.E.3
Faretta, M.4
Ronzoni, S.5
Giulini, B.6
Brisken, C.7
Minucci, S.8
Di Fiore, P.P.9
Pelicci, P.G.10
-
128
-
-
84864764964
-
Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17
-
J. Guinea-Viniegra, R. Zenz, H. Scheuch, M. Jimenez, L. Bakiri, P. Petzelbauer, and E.F. Wagner Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17 J. Clin. Investig. 122 2012 2898 2910
-
(2012)
J. Clin. Investig.
, vol.122
, pp. 2898-2910
-
-
Guinea-Viniegra, J.1
Zenz, R.2
Scheuch, H.3
Jimenez, M.4
Bakiri, L.5
Petzelbauer, P.6
Wagner, E.F.7
-
129
-
-
77956407620
-
Hedgehog pathway activation in chronic myeloid leukemia
-
Z. Jagani, M. Dorsch, and M. Warmuth Hedgehog pathway activation in chronic myeloid leukemia Cell Cycle 9 2010 3449 3456
-
(2010)
Cell Cycle
, vol.9
, pp. 3449-3456
-
-
Jagani, Z.1
Dorsch, M.2
Warmuth, M.3
-
130
-
-
84862517728
-
Cancer stem cells: Current status and evolving complexities
-
J.E. Visvader, and G.J. Lindeman Cancer stem cells: current status and evolving complexities Cell Stem Cell 10 2012 717 728
-
(2012)
Cell Stem Cell
, vol.10
, pp. 717-728
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
131
-
-
84856963775
-
Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype
-
J. Jiang, Y. Zhang, S. Chuai, Z. Wang, D. Zheng, F. Xu, Y. Zhang, C. Li, Y. Liang, and Z. Chen Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype Oncogene 31 2012 671 682
-
(2012)
Oncogene
, vol.31
, pp. 671-682
-
-
Jiang, J.1
Zhang, Y.2
Chuai, S.3
Wang, Z.4
Zheng, D.5
Xu, F.6
Zhang, Y.7
Li, C.8
Liang, Y.9
Chen, Z.10
-
132
-
-
84867919330
-
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
-
S.M. McAuliffe, S.L. Morgan, G.A. Wyant, L.T. Tran, K.W. Muto, Y.S. Chen, K.T. Chin, J.C. Partridge, B.B. Poole, K.H. Cheng, J. Daggett Jr.; K. Cullen, E. Kantoff, K. Hasselbatt, J. Berkowitz, M.G. Muto, R.S. Berkowitz, J.C. Aster, U.A. Matulonis, and D.M. Dinulescu Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy Proc. Natl. Acad. Sci. USA 109 2012 E2939 E2948
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
-
-
McAuliffe, S.M.1
Morgan, S.L.2
Wyant, G.A.3
Tran, L.T.4
Muto, K.W.5
Chen, Y.S.6
Chin, K.T.7
Partridge, J.C.8
Poole, B.B.9
Cheng, K.H.10
Daggett, Jr.J.11
Cullen, K.12
Kantoff, E.13
Hasselbatt, K.14
Berkowitz, J.15
Muto, M.G.16
Berkowitz, R.S.17
Aster, J.C.18
Matulonis, U.A.19
Dinulescu, D.M.20
more..
-
133
-
-
75149117750
-
Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop
-
V. Levina, A. Marrangoni, T. Wang, S. Parikh, Y. Su, R. Herberman, A. Lokshin, and E. Gorelik Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop Cancer Res. 70 2010 338 346
-
(2010)
Cancer Res.
, vol.70
, pp. 338-346
-
-
Levina, V.1
Marrangoni, A.2
Wang, T.3
Parikh, S.4
Su, Y.5
Herberman, R.6
Lokshin, A.7
Gorelik, E.8
-
134
-
-
34848866647
-
Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4
-
M. Todaro, M.P. Alea, A.B. Di Stefano, P. Cammareri, L. Vermeulen, F. Iovino, C. Tripodo, A. Russo, G. Gulotta, J.P. Medema, and G. Stassi Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4 Cell Stem Cell 1 2007 389 402
-
(2007)
Cell Stem Cell
, vol.1
, pp. 389-402
-
-
Todaro, M.1
Alea, M.P.2
Di Stefano, A.B.3
Cammareri, P.4
Vermeulen, L.5
Iovino, F.6
Tripodo, C.7
Russo, A.8
Gulotta, G.9
Medema, J.P.10
Stassi, G.11
-
135
-
-
84862740746
-
The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells
-
C. Huang, X.M. Zhang, R.T. Tavaluc, L.S. Hart, D.T. Dicker, W. Wang, and W.S. El-Deiry The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells Cancer Biol. Ther. 8 2009 2186 2193
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 2186-2193
-
-
Huang, C.1
Zhang, X.M.2
Tavaluc, R.T.3
Hart, L.S.4
Dicker, D.T.5
Wang, W.6
El-Deiry, W.S.7
-
136
-
-
84868015363
-
Loss of p53 exacerbates multiple myeloma phenotype by facilitating the reprogramming of hematopoietic stem/progenitor cells to malignant plasma cells by MafB
-
C. Vicente-Duenas, I. Gonzalez-Herrero, M.B. Garcia Cenador, F.J. Garcia Criado, and I. Sanchez-Garcia Loss of p53 exacerbates multiple myeloma phenotype by facilitating the reprogramming of hematopoietic stem/progenitor cells to malignant plasma cells by MafB Cell Cycle 11 2012 3896 3900
-
(2012)
Cell Cycle
, vol.11
, pp. 3896-3900
-
-
Vicente-Duenas, C.1
Gonzalez-Herrero, I.2
Garcia Cenador, M.B.3
Garcia Criado, F.J.4
Sanchez-Garcia, I.5
-
137
-
-
70349985246
-
Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice
-
P.P. Lin, M.K. Pandey, F. Jin, A.K. Raymond, H. Akiyama, and G. Lozano Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice Carcinogenesis 30 2009 1789 1795
-
(2009)
Carcinogenesis
, vol.30
, pp. 1789-1795
-
-
Lin, P.P.1
Pandey, M.K.2
Jin, F.3
Raymond, A.K.4
Akiyama, H.5
Lozano, G.6
-
138
-
-
84869878282
-
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice
-
D. Friedmann-Morvinski, E.A. Bushong, E. Ke, Y. Soda, T. Marumoto, O. Singer, M.H. Ellisman, and I.M. Verma Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice Science 338 2012 1080 1084
-
(2012)
Science
, vol.338
, pp. 1080-1084
-
-
Friedmann-Morvinski, D.1
Bushong, E.A.2
Ke, E.3
Soda, Y.4
Marumoto, T.5
Singer, O.6
Ellisman, M.H.7
Verma, I.M.8
-
139
-
-
80755187837
-
Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells
-
T. Motohara, S. Masuko, T. Ishimoto, T. Yae, N. Onishi, T. Muraguchi, A. Hirao, Y. Matsuzaki, H. Tashiro, H. Katabuchi, H. Saya, and O. Nagano Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells Carcinogenesis 32 2011 1597 1606
-
(2011)
Carcinogenesis
, vol.32
, pp. 1597-1606
-
-
Motohara, T.1
Masuko, S.2
Ishimoto, T.3
Yae, T.4
Onishi, N.5
Muraguchi, T.6
Hirao, A.7
Matsuzaki, Y.8
Tashiro, H.9
Katabuchi, H.10
Saya, H.11
Nagano, O.12
-
140
-
-
0034024715
-
Mutation of p53 with loss of heterozygosity in the osteosarcomatous component of a dedifferentiated chondrosarcoma
-
H.J. Grote, R. Schneider-Stock, W. Neumann, and A. Roessner Mutation of p53 with loss of heterozygosity in the osteosarcomatous component of a dedifferentiated chondrosarcoma Virchows Arch. 436 2000 494 497
-
(2000)
Virchows Arch.
, vol.436
, pp. 494-497
-
-
Grote, H.J.1
Schneider-Stock, R.2
Neumann, W.3
Roessner, A.4
-
141
-
-
80051790113
-
Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells
-
J.H. Moon, S. Kwon, E.K. Jun, A. Kim, K.Y. Whang, H. Kim, S. Oh, B.S. Yoon, and S. You Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells Biochem. Biophys. Res. Commun. 412 2011 175 181
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.412
, pp. 175-181
-
-
Moon, J.H.1
Kwon, S.2
Jun, E.K.3
Kim, A.4
Whang, K.Y.5
Kim, H.6
Oh, S.7
Yoon, B.S.8
You, S.9
-
142
-
-
84880764103
-
"dedifferentiation" and high-grade transformation in salivary gland carcinomas
-
T. Nagao "Dedifferentiation" and high-grade transformation in salivary gland carcinomas Head Neck Pathol. 7 Suppl. 1 2013 S37 47
-
(2013)
Head Neck Pathol.
, vol.7
, Issue.SUPPL. 1
, pp. 37-47
-
-
Nagao, T.1
-
143
-
-
0346992282
-
Dedifferentiated adenoid cystic carcinoma: A clinicopathologic study of 6 cases
-
T. Nagao, T.A. Gaffey, H. Serizawa, I. Sugano, Y. Ishida, K. Yamazaki, R. Tokashiki, T. Yoshida, H. Minato, P.A. Kay, and J.E. Lewis Dedifferentiated adenoid cystic carcinoma: a clinicopathologic study of 6 cases Mod. Pathol. 16 2003 1265 1272
-
(2003)
Mod. Pathol.
, vol.16
, pp. 1265-1272
-
-
Nagao, T.1
Gaffey, T.A.2
Serizawa, H.3
Sugano, I.4
Ishida, Y.5
Yamazaki, K.6
Tokashiki, R.7
Yoshida, T.8
Minato, H.9
Kay, P.A.10
Lewis, J.E.11
-
144
-
-
82055176819
-
Genetic alterations in poorly differentiated and undifferentiated thyroid carcinomas
-
P. Soares, J. Lima, A. Preto, P. Castro, J. Vinagre, R. Celestino, J.P. Couto, H. Prazeres, C. Eloy, V. Maximo, and M. Sobrinho-Simoes Genetic alterations in poorly differentiated and undifferentiated thyroid carcinomas Curr. Genomics 12 2011 609 617
-
(2011)
Curr. Genomics
, vol.12
, pp. 609-617
-
-
Soares, P.1
Lima, J.2
Preto, A.3
Castro, P.4
Vinagre, J.5
Celestino, R.6
Couto, J.P.7
Prazeres, H.8
Eloy, C.9
Maximo, V.10
Sobrinho-Simoes, M.11
-
145
-
-
0027189664
-
Genetic alterations in thyroid tumor progression: Association with p53 gene mutations
-
T. Ito, T. Seyama, T. Mizuno, N. Tsuyama, Y. Hayashi, K. Dohi, N. Nakamura, and M. Akiyama Genetic alterations in thyroid tumor progression: association with p53 gene mutations Jpn. J. Cancer Res. 84 1993 526 531
-
(1993)
Jpn. J. Cancer Res.
, vol.84
, pp. 526-531
-
-
Ito, T.1
Seyama, T.2
Mizuno, T.3
Tsuyama, N.4
Hayashi, Y.5
Dohi, K.6
Nakamura, N.7
Akiyama, M.8
-
146
-
-
84880060556
-
Bilateral wilms tumor with TP53-related anaplasia
-
S.D. Popov, G.M. Vujanic, N.J. Sebire, T. Chagtai, R. Williams, S. Vaidya, and K. Pritchard-Jones Bilateral wilms tumor with TP53-related anaplasia Pediatr. Dev. Pathol. 16 2013 217 223
-
(2013)
Pediatr. Dev. Pathol.
, vol.16
, pp. 217-223
-
-
Popov, S.D.1
Vujanic, G.M.2
Sebire, N.J.3
Chagtai, T.4
Williams, R.5
Vaidya, S.6
Pritchard-Jones, K.7
-
147
-
-
33745432825
-
How wild-type TP53 is inactivated in undifferentiated-type gastric carcinomas: Analyses of intratumoral heterogeneity in deletion and mutation of TP53
-
A. Yoshimura, H. Sugihara, Z.Q. Ling, D.F. Peng, K. Mukaisho, Y. Fujiyama, and T. Hattori How wild-type TP53 is inactivated in undifferentiated-type gastric carcinomas: analyses of intratumoral heterogeneity in deletion and mutation of TP53 Pathobiology 73 2006 40 49
-
(2006)
Pathobiology
, vol.73
, pp. 40-49
-
-
Yoshimura, A.1
Sugihara, H.2
Ling, Z.Q.3
Peng, D.F.4
Mukaisho, K.5
Fujiyama, Y.6
Hattori, T.7
-
148
-
-
1242351324
-
The TP53-ARF tumor suppressor pathway is frequently disrupted in large/cell anaplastic medulloblastoma
-
A.J. Frank, R. Hernan, A. Hollander, J.C. Lindsey, M.E. Lusher, C.E. Fuller, S.C. Clifford, and R.J. Gilbertson The TP53-ARF tumor suppressor pathway is frequently disrupted in large/cell anaplastic medulloblastoma Brain Res. Mol. Brain Res. 121 2004 137 140
-
(2004)
Brain Res. Mol. Brain Res.
, vol.121
, pp. 137-140
-
-
Frank, A.J.1
Hernan, R.2
Hollander, A.3
Lindsey, J.C.4
Lusher, M.E.5
Fuller, C.E.6
Clifford, S.C.7
Gilbertson, R.J.8
-
149
-
-
26844469719
-
Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus
-
C.G. Eberhart, A. Chaudhry, R.W. Daniel, L. Khaki, K.V. Shah, and P.E. Gravitt Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus BMC Cancer 5 2005 19
-
(2005)
BMC Cancer
, vol.5
, pp. 19
-
-
Eberhart, C.G.1
Chaudhry, A.2
Daniel, R.W.3
Khaki, L.4
Shah, K.V.5
Gravitt, P.E.6
-
150
-
-
13144250127
-
P53 overexpression in small hepatocellular carcinomas containing two different histologic grades
-
Y. Nakashima, C.C. Hsia, H. Yuwen, M. Minemura, O. Nakashima, M. Kojiro, and E. Tabor p53 overexpression in small hepatocellular carcinomas containing two different histologic grades Int. J. Oncol. 12 1998 455 459
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 455-459
-
-
Nakashima, Y.1
Hsia, C.C.2
Yuwen, H.3
Minemura, M.4
Nakashima, O.5
Kojiro, M.6
Tabor, E.7
-
151
-
-
0034241501
-
Relationship between p53 overexpression and the proliferative activity in hepatocellular carcinoma
-
T. Itoh, T. Shiro, T. Seki, T. Nakagawa, M. Wakabayashi, K. Inoue, and A. Okamura Relationship between p53 overexpression and the proliferative activity in hepatocellular carcinoma Int. J. Mol. Med. 6 2000 137 142
-
(2000)
Int. J. Mol. Med.
, vol.6
, pp. 137-142
-
-
Itoh, T.1
Shiro, T.2
Seki, T.3
Nakagawa, T.4
Wakabayashi, M.5
Inoue, K.6
Okamura, A.7
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