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Volumn 588, Issue 16, 2014, Pages 2580-2589

P53: The barrier to cancer stem cell formation

Author keywords

Cancer stem cells; Loss of heterozygosity; p53; Stem cells; Tumorigenesis

Indexed keywords

FLUOROURACIL; PROTEIN P53; TRASTUZUMAB;

EID: 84905086482     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.02.011     Document Type: Review
Times cited : (100)

References (151)
  • 1
    • 0027109075 scopus 로고
    • Cancer. P53, guardian of the genome
    • D.P. Lane Cancer. p53, guardian of the genome Nature 358 1992 15 16
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 2
    • 69949085788 scopus 로고    scopus 로고
    • Genome instability, cancer and aging
    • A.Y. Maslov, and J. Vijg Genome instability, cancer and aging Biochim. Biophys. Acta 1790 2009 963 969
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 963-969
    • Maslov, A.Y.1    Vijg, J.2
  • 6
    • 13944273471 scopus 로고    scopus 로고
    • P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
    • T. Lin, C. Chao, S. Saito, S.J. Mazur, M.E. Murphy, E. Appella, and Y. Xu p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression Nat. Cell Biol. 7 2005 165 171
    • (2005) Nat. Cell Biol. , vol.7 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3    Mazur, S.J.4    Murphy, M.E.5    Appella, E.6    Xu, Y.7
  • 7
    • 0027452415 scopus 로고
    • Wild type p53 functions as a control protein in the differentiation pathway of the B-cell lineage
    • R. Aloni-Grinstein, I. Zan-Bar, I. Alboum, N. Goldfinger, and V. Rotter Wild type p53 functions as a control protein in the differentiation pathway of the B-cell lineage Oncogene 8 1993 3297 3305
    • (1993) Oncogene , vol.8 , pp. 3297-3305
    • Aloni-Grinstein, R.1    Zan-Bar, I.2    Alboum, I.3    Goldfinger, N.4    Rotter, V.5
  • 16
    • 0346562866 scopus 로고    scopus 로고
    • Derivation of embryonic germ cells and male gametes from embryonic stem cells
    • N. Geijsen, M. Horoschak, K. Kim, J. Gribnau, K. Eggan, and G.Q. Daley Derivation of embryonic germ cells and male gametes from embryonic stem cells Nature 427 2004 148 154
    • (2004) Nature , vol.427 , pp. 148-154
    • Geijsen, N.1    Horoschak, M.2    Kim, K.3    Gribnau, J.4    Eggan, K.5    Daley, G.Q.6
  • 18
    • 66449121507 scopus 로고    scopus 로고
    • Stem cells use distinct self-renewal programs at different ages
    • B.P. Levi, and S.J. Morrison Stem cells use distinct self-renewal programs at different ages Cold Spring Harb. Symp. Quant. Biol. 73 2008 539 553
    • (2008) Cold Spring Harb. Symp. Quant. Biol. , vol.73 , pp. 539-553
    • Levi, B.P.1    Morrison, S.J.2
  • 19
    • 0000155376 scopus 로고
    • The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles
    • J.B. Gurdon The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles J. Embryol. Exp. Morphol. 10 1962 622 640
    • (1962) J. Embryol. Exp. Morphol. , vol.10 , pp. 622-640
    • Gurdon, J.B.1
  • 20
    • 0000331391 scopus 로고
    • Adult frogs derived from the nuclei of single somatic cells
    • J.B. Gurdon Adult frogs derived from the nuclei of single somatic cells Dev. Biol. 4 1962 256 273
    • (1962) Dev. Biol. , vol.4 , pp. 256-273
    • Gurdon, J.B.1
  • 22
    • 0020960766 scopus 로고
    • Cytoplasmic activation of human nuclear genes in stable heterocaryons
    • H.M. Blau, C.P. Chiu, and C. Webster Cytoplasmic activation of human nuclear genes in stable heterocaryons Cell 32 1983 1171 1180
    • (1983) Cell , vol.32 , pp. 1171-1180
    • Blau, H.M.1    Chiu, C.P.2    Webster, C.3
  • 23
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 24
    • 84892940152 scopus 로고    scopus 로고
    • Nonviral delivery for reprogramming to pluripotency and differentiation
    • H.J. Park, J. Shin, J. Kim, and S.W. Cho Nonviral delivery for reprogramming to pluripotency and differentiation Arch. Pharm. Res. 37 2014 107 119
    • (2014) Arch. Pharm. Res. , vol.37 , pp. 107-119
    • Park, H.J.1    Shin, J.2    Kim, J.3    Cho, S.W.4
  • 26
    • 84877978530 scopus 로고    scopus 로고
    • Mechanisms and models of somatic cell reprogramming
    • Y. Buganim, D.A. Faddah, and R. Jaenisch Mechanisms and models of somatic cell reprogramming Nat. Rev. Genet. 14 2013 427 439
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 427-439
    • Buganim, Y.1    Faddah, D.A.2    Jaenisch, R.3
  • 28
    • 77954922985 scopus 로고    scopus 로고
    • Stem cells in cancer: Instigators and propagators?
    • M.R. Alison, S. Islam, and N.A. Wright Stem cells in cancer: instigators and propagators? J. Cell Sci. 123 2010 2357 2368
    • (2010) J. Cell Sci. , vol.123 , pp. 2357-2368
    • Alison, M.R.1    Islam, S.2    Wright, N.A.3
  • 29
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • H.F. Dvorak Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing N. Engl. J. Med. 315 1986 1650 1659
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 33
    • 22244433866 scopus 로고    scopus 로고
    • Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
    • L. Patrawala, T. Calhoun, R. Schneider-Broussard, J. Zhou, K. Claypool, and D.G. Tang Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic Cancer Res. 65 2005 6207 6219
    • (2005) Cancer Res. , vol.65 , pp. 6207-6219
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3    Zhou, J.4    Claypool, K.5    Tang, D.G.6
  • 34
    • 2342601849 scopus 로고    scopus 로고
    • In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
    • Y. Yuan, H. Shen, D.S. Franklin, D.T. Scadden, and T. Cheng In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C Nat. Cell Biol. 6 2004 436 442
    • (2004) Nat. Cell Biol. , vol.6 , pp. 436-442
    • Yuan, Y.1    Shen, H.2    Franklin, D.S.3    Scadden, D.T.4    Cheng, T.5
  • 36
    • 33644826473 scopus 로고    scopus 로고
    • Roots and stems: Stem cells in cancer
    • K. Polyak, and W.C. Hahn Roots and stems: stem cells in cancer Nat. Med. 12 2006 296 300
    • (2006) Nat. Med. , vol.12 , pp. 296-300
    • Polyak, K.1    Hahn, W.C.2
  • 38
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • M. Dean, T. Fojo, and S. Bates Tumour stem cells and drug resistance Nat. Rev. Cancer 5 2005 275 284
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 39
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: Premises, promises and challenges
    • H. Clevers The cancer stem cell: premises, promises and challenges Nat. Med. 17 2011 313 319
    • (2011) Nat. Med. , vol.17 , pp. 313-319
    • Clevers, H.1
  • 42
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • D. Bonnet, and J.E. Dick Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat. Med. 3 1997 730 737
    • (1997) Nat. Med. , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 45
    • 84886399680 scopus 로고    scopus 로고
    • Regulation of p53 is critical for vertebrate limb regeneration
    • M.H. Yun, P.B. Gates, and J.P. Brockes Regulation of p53 is critical for vertebrate limb regeneration Proc. Natl. Acad. Sci. USA 110 2013 17392 17397
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 17392-17397
    • Yun, M.H.1    Gates, P.B.2    Brockes, J.P.3
  • 47
    • 0022390692 scopus 로고
    • P53 cellular tumor antigen: Analysis of mRNA levels in normal adult tissues, embryos, and tumors
    • A. Rogel, M. Popliker, C.G. Webb, and M. Oren p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors Mol. Cell. Biol. 5 1985 2851 2855
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 2851-2855
    • Rogel, A.1    Popliker, M.2    Webb, C.G.3    Oren, M.4
  • 48
    • 0019164934 scopus 로고
    • An embryo protein induced by SV40 virus transformation of mouse cells
    • P.T. Mora, K. Chandrasekaran, and V.W. McFarland An embryo protein induced by SV40 virus transformation of mouse cells Nature 288 1980 722 724
    • (1980) Nature , vol.288 , pp. 722-724
    • Mora, P.T.1    Chandrasekaran, K.2    McFarland, V.W.3
  • 49
    • 0019792349 scopus 로고
    • Quantitation and characterization of a species-specific and embryo stage-dependent 55-kilodalton phosphoprotein also present in cells transformed by simian virus 40
    • K. Chandrasekaran, V.W. McFarland, D.T. Simmons, M. Dziadek, E.G. Gurney, and P.T. Mora Quantitation and characterization of a species-specific and embryo stage-dependent 55-kilodalton phosphoprotein also present in cells transformed by simian virus 40 Proc. Natl. Acad. Sci. USA 78 1981 6953 6957
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 6953-6957
    • Chandrasekaran, K.1    McFarland, V.W.2    Simmons, D.T.3    Dziadek, M.4    Gurney, E.G.5    Mora, P.T.6
  • 51
    • 0030663519 scopus 로고    scopus 로고
    • Regulation of ES cell differentiation by functional and conformational modulation of p53
    • K. Sabapathy, M. Klemm, R. Jaenisch, and E.F. Wagner Regulation of ES cell differentiation by functional and conformational modulation of p53 EMBO J. 16 1997 6217 6229
    • (1997) EMBO J. , vol.16 , pp. 6217-6229
    • Sabapathy, K.1    Klemm, M.2    Jaenisch, R.3    Wagner, E.F.4
  • 52
    • 39749087530 scopus 로고    scopus 로고
    • SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
    • M.K. Han, E.K. Song, Y. Guo, X. Ou, C. Mantel, and H.E. Broxmeyer SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization Cell Stem Cell 2 2008 241 251
    • (2008) Cell Stem Cell , vol.2 , pp. 241-251
    • Han, M.K.1    Song, E.K.2    Guo, Y.3    Ou, X.4    Mantel, C.5    Broxmeyer, H.E.6
  • 53
    • 44249101836 scopus 로고    scopus 로고
    • P53 is required for etoposide-induced apoptosis of human embryonic stem cells
    • C. Grandela, M.F. Pera, S.M. Grimmond, G. Kolle, and E.J. Wolvetang p53 is required for etoposide-induced apoptosis of human embryonic stem cells Stem Cell Res. 1 2007 116 128
    • (2007) Stem Cell Res. , vol.1 , pp. 116-128
    • Grandela, C.1    Pera, M.F.2    Grimmond, S.M.3    Kolle, G.4    Wolvetang, E.J.5
  • 55
    • 0032576768 scopus 로고    scopus 로고
    • ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
    • M.I. Aladjem, B.T. Spike, L.W. Rodewald, T.J. Hope, M. Klemm, R. Jaenisch, and G.M. Wahl ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage Curr. Biol. 8 1998 145 155
    • (1998) Curr. Biol. , vol.8 , pp. 145-155
    • Aladjem, M.I.1    Spike, B.T.2    Rodewald, L.W.3    Hope, T.J.4    Klemm, M.5    Jaenisch, R.6    Wahl, G.M.7
  • 60
    • 84891823754 scopus 로고    scopus 로고
    • Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation
    • Z.N. Zhang, S.K. Chung, Z. Xu, and Y. Xu Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation Stem Cells 32 2014 157 165
    • (2014) Stem Cells , vol.32 , pp. 157-165
    • Zhang, Z.N.1    Chung, S.K.2    Xu, Z.3    Xu, Y.4
  • 62
    • 84891775193 scopus 로고    scopus 로고
    • Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells
    • K.C. Akdemir, A.K. Jain, K. Allton, B. Aronow, X. Xu, A.J. Cooney, W. Li, and M.C. Barton Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells Nucleic Acids Res. 42 2014 205 223
    • (2014) Nucleic Acids Res. , vol.42 , pp. 205-223
    • Akdemir, K.C.1    Jain, A.K.2    Allton, K.3    Aronow, B.4    Xu, X.5    Cooney, A.J.6    Li, W.7    Barton, M.C.8
  • 63
    • 77954758157 scopus 로고    scopus 로고
    • Polycomb group protein-mediated repression of transcription
    • L. Morey, and K. Helin Polycomb group protein-mediated repression of transcription Trends Biochem. Sci. 35 2010 323 332
    • (2010) Trends Biochem. Sci. , vol.35 , pp. 323-332
    • Morey, L.1    Helin, K.2
  • 72
    • 73949130140 scopus 로고    scopus 로고
    • Effective generation of iPS cells from CD34(+) cord blood cells by inhibition of p53
    • C. Takenaka, N. Nishishita, N. Takada, L.M. Jakt, and S. Kawamata Effective generation of iPS cells from CD34(+) cord blood cells by inhibition of p53 Exp. Hematol. 38 2010 154 162
    • (2010) Exp. Hematol. , vol.38 , pp. 154-162
    • Takenaka, C.1    Nishishita, N.2    Takada, N.3    Jakt, L.M.4    Kawamata, S.5
  • 74
    • 77957733786 scopus 로고    scopus 로고
    • P53 connects tumorigenesis and reprogramming to pluripotency
    • N. Tapia, and H.R. Scholer p53 connects tumorigenesis and reprogramming to pluripotency J. Exp. Med. 207 2010 2045 2048
    • (2010) J. Exp. Med. , vol.207 , pp. 2045-2048
    • Tapia, N.1    Scholer, H.R.2
  • 76
    • 84862843347 scopus 로고    scopus 로고
    • P53-facilitated miR-199a-3p regulates somatic cell reprogramming
    • J. Wang, Q. He, C. Han, H. Gu, L. Jin, Q. Li, Y. Mei, and M. Wu p53-facilitated miR-199a-3p regulates somatic cell reprogramming Stem Cells 30 2012 1405 1413
    • (2012) Stem Cells , vol.30 , pp. 1405-1413
    • Wang, J.1    He, Q.2    Han, C.3    Gu, H.4    Jin, L.5    Li, Q.6    Mei, Y.7    Wu, M.8
  • 79
    • 84868224979 scopus 로고    scopus 로고
    • Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation
    • L. Yi, C. Lu, W. Hu, Y. Sun, and A.J. Levine Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation Cancer Res. 72 2012 5635 5645
    • (2012) Cancer Res. , vol.72 , pp. 5635-5645
    • Yi, L.1    Lu, C.2    Hu, W.3    Sun, Y.4    Levine, A.J.5
  • 81
    • 77950265945 scopus 로고    scopus 로고
    • Linking functional decline of telomeres, mitochondria and stem cells during ageing
    • E. Sahin, and R.A. Depinho Linking functional decline of telomeres, mitochondria and stem cells during ageing Nature 464 2010 520 528
    • (2010) Nature , vol.464 , pp. 520-528
    • Sahin, E.1    Depinho, R.A.2
  • 85
    • 70449521174 scopus 로고    scopus 로고
    • P53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells
    • A. Armesilla-Diaz, G. Elvira, and A. Silva p53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells Exp. Cell Res. 315 2009 3598 3610
    • (2009) Exp. Cell Res. , vol.315 , pp. 3598-3610
    • Armesilla-Diaz, A.1    Elvira, G.2    Silva, A.3
  • 86
    • 77950645030 scopus 로고    scopus 로고
    • Age-related molecular genetic changes of murine bone marrow mesenchymal stem cells
    • A. Wilson, L.A. Shehadeh, H. Yu, and K.A. Webster Age-related molecular genetic changes of murine bone marrow mesenchymal stem cells BMC Genomics 11 2010 229
    • (2010) BMC Genomics , vol.11 , pp. 229
    • Wilson, A.1    Shehadeh, L.A.2    Yu, H.3    Webster, K.A.4
  • 89
    • 79953000341 scopus 로고    scopus 로고
    • Concise review: Mesenchymal tumors: When stem cells go mad
    • A.B. Mohseny, and P.C. Hogendoorn Concise review: mesenchymal tumors: when stem cells go mad Stem Cells 29 2011 397 403
    • (2011) Stem Cells , vol.29 , pp. 397-403
    • Mohseny, A.B.1    Hogendoorn, P.C.2
  • 90
    • 84855477391 scopus 로고    scopus 로고
    • Modeling sarcomagenesis using multipotent mesenchymal stem cells
    • R. Rodriguez, R. Rubio, and P. Menendez Modeling sarcomagenesis using multipotent mesenchymal stem cells Cell Res. 22 2012 62 77
    • (2012) Cell Res. , vol.22 , pp. 62-77
    • Rodriguez, R.1    Rubio, R.2    Menendez, P.3
  • 96
    • 0027203921 scopus 로고
    • Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
    • C.J. Kemp, L.A. Donehower, A. Bradley, and A. Balmain Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors Cell 74 1993 813 822
    • (1993) Cell , vol.74 , pp. 813-822
    • Kemp, C.J.1    Donehower, L.A.2    Bradley, A.3    Balmain, A.4
  • 97
    • 0027455042 scopus 로고
    • High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
    • J.A. Fagin, K. Matsuo, A. Karmakar, D.L. Chen, S.H. Tang, and H.P. Koeffler High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas J. Clin. Investig. 91 1993 179 184
    • (1993) J. Clin. Investig. , vol.91 , pp. 179-184
    • Fagin, J.A.1    Matsuo, K.2    Karmakar, A.3    Chen, D.L.4    Tang, S.H.5    Koeffler, H.P.6
  • 98
    • 0027215123 scopus 로고
    • Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland
    • R. Donghi, A. Longoni, S. Pilotti, P. Michieli, G. Della Porta, and M.A. Pierotti Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland J. Clin. Investig. 91 1993 1753 1760
    • (1993) J. Clin. Investig. , vol.91 , pp. 1753-1760
    • Donghi, R.1    Longoni, A.2    Pilotti, S.3    Michieli, P.4    Della Porta, G.5    Pierotti, M.A.6
  • 99
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • I. Ben-Porath, M.W. Thomson, V.J. Carey, R. Ge, G.W. Bell, A. Regev, and R.A. Weinberg An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors Nat. Genet. 40 2008 499 507
    • (2008) Nat. Genet. , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 100
    • 78651100119 scopus 로고    scopus 로고
    • Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures
    • H. Mizuno, B.T. Spike, G.M. Wahl, and A.J. Levine Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures Proc. Natl. Acad. Sci. USA 107 2010 22745 22750
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 22745-22750
    • Mizuno, H.1    Spike, B.T.2    Wahl, G.M.3    Levine, A.J.4
  • 101
    • 84855484465 scopus 로고    scopus 로고
    • Molecular classification of prostate cancer using curated expression signatures
    • E.K. Markert, H. Mizuno, A. Vazquez, and A.J. Levine Molecular classification of prostate cancer using curated expression signatures Proc. Natl. Acad. Sci. USA 108 2011 21276 21281
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 21276-21281
    • Markert, E.K.1    Mizuno, H.2    Vazquez, A.3    Levine, A.J.4
  • 105
    • 0030957152 scopus 로고    scopus 로고
    • Li-Fraumeni syndrome - A molecular and clinical review
    • J.M. Varley, D.G. Evans, and J.M. Birch Li-Fraumeni syndrome - A molecular and clinical review Br. J. Cancer 76 1997 1 14
    • (1997) Br. J. Cancer , vol.76 , pp. 1-14
    • Varley, J.M.1    Evans, D.G.2    Birch, J.M.3
  • 106
    • 0035049323 scopus 로고    scopus 로고
    • Methylation in the p53 promoter is a supplementary route to breast carcinogenesis: Correlation between CpG methylation in the p53 promoter and the mutation of the p53 gene in the progression from ductal carcinoma in situ to invasive ductal carcinoma
    • J.H. Kang, S.J. Kim, D.Y. Noh, I.A. Park, K.J. Choe, O.J. Yoo, and H.S. Kang Methylation in the p53 promoter is a supplementary route to breast carcinogenesis: correlation between CpG methylation in the p53 promoter and the mutation of the p53 gene in the progression from ductal carcinoma in situ to invasive ductal carcinoma Lab. Invest. 81 2001 573 579
    • (2001) Lab. Invest. , vol.81 , pp. 573-579
    • Kang, J.H.1    Kim, S.J.2    Noh, D.Y.3    Park, I.A.4    Choe, K.J.5    Yoo, O.J.6    Kang, H.S.7
  • 108
    • 33749128524 scopus 로고    scopus 로고
    • Unique substitution of CHEK2 and TP53 mutations implicated in primary prostate tumors and cancer cell lines
    • L. Zheng, F. Wang, C. Qian, R.M. Neumann, J.C. Cheville, D.J. Tindall, and W. Liu Unique substitution of CHEK2 and TP53 mutations implicated in primary prostate tumors and cancer cell lines Hum. Mutat. 27 2006 1062 1063
    • (2006) Hum. Mutat. , vol.27 , pp. 1062-1063
    • Zheng, L.1    Wang, F.2    Qian, C.3    Neumann, R.M.4    Cheville, J.C.5    Tindall, D.J.6    Liu, W.7
  • 109
    • 80053039210 scopus 로고    scopus 로고
    • Mutations in the p53 tumor suppressor gene: Important milestones at the various steps of tumorigenesis
    • N. Rivlin, R. Brosh, M. Oren, and V. Rotter Mutations in the p53 tumor suppressor gene: important milestones at the various steps of tumorigenesis Genes Cancer 2 2011 466 474
    • (2011) Genes Cancer , vol.2 , pp. 466-474
    • Rivlin, N.1    Brosh, R.2    Oren, M.3    Rotter, V.4
  • 111
    • 78650027929 scopus 로고    scopus 로고
    • Haplo-insufficiency: A driving force in cancer
    • A.H. Berger, and P.P. Pandolfi Haplo-insufficiency: a driving force in cancer J. Pathol. 223 2011 137 146
    • (2011) J. Pathol. , vol.223 , pp. 137-146
    • Berger, A.H.1    Pandolfi, P.P.2
  • 112
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
    • A. Petitjean, E. Mathe, S. Kato, C. Ishioka, S.V. Tavtigian, P. Hainaut, and M. Olivier Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database Hum. Mutat. 28 2007 622 629
    • (2007) Hum. Mutat. , vol.28 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3    Ishioka, C.4    Tavtigian, S.V.5    Hainaut, P.6    Olivier, M.7
  • 114
    • 0141819143 scopus 로고    scopus 로고
    • An age-induced switch to a hyper-recombinational state
    • M.A. McMurray, and D.E. Gottschling An age-induced switch to a hyper-recombinational state Science 301 2003 1908 1911
    • (2003) Science , vol.301 , pp. 1908-1911
    • McMurray, M.A.1    Gottschling, D.E.2
  • 115
    • 0042027816 scopus 로고    scopus 로고
    • Treatment of acute promyelocytic leukemia: Strategy toward further increase of cure rate
    • R. Ohno, N. Asou, and K. Ohnishi Treatment of acute promyelocytic leukemia: strategy toward further increase of cure rate Leukemia 17 2003 1454 1463
    • (2003) Leukemia , vol.17 , pp. 1454-1463
    • Ohno, R.1    Asou, N.2    Ohnishi, K.3
  • 120
    • 84878002317 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: An attractive strategy for cancer therapy
    • J. Li, G. Li, and W. Xu Histone deacetylase inhibitors: an attractive strategy for cancer therapy Curr. Med. Chem. 20 2013 1858 1886
    • (2013) Curr. Med. Chem. , vol.20 , pp. 1858-1886
    • Li, J.1    Li, G.2    Xu, W.3
  • 121
    • 84901335119 scopus 로고    scopus 로고
    • MicroRNAs as novel regulators of stem cell fate
    • E. Choi, E. Choi, and K.C. Hwang MicroRNAs as novel regulators of stem cell fate World J. Stem Cells 5 2013 172 187
    • (2013) World J. Stem Cells , vol.5 , pp. 172-187
    • Choi, E.1    Choi, E.2    Hwang, K.C.3
  • 125
    • 0032568329 scopus 로고    scopus 로고
    • Stable reintroduction of wild-type P53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells
    • D. Lang, S.J. Miknyoczki, L. Huang, and B.A. Ruggeri Stable reintroduction of wild-type P53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells Oncogene 16 1998 1593 1602
    • (1998) Oncogene , vol.16 , pp. 1593-1602
    • Lang, D.1    Miknyoczki, S.J.2    Huang, L.3    Ruggeri, B.A.4
  • 126
    • 0028337504 scopus 로고
    • Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53
    • R. Radinsky, I.J. Fidler, J.E. Price, N. Esumi, R. Tsan, C.M. Petty, C.D. Bucana, and M. Bar-Eli Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53 Oncogene 9 1994 1877 1883
    • (1994) Oncogene , vol.9 , pp. 1877-1883
    • Radinsky, R.1    Fidler, I.J.2    Price, J.E.3    Esumi, N.4    Tsan, R.5    Petty, C.M.6    Bucana, C.D.7    Bar-Eli, M.8
  • 129
    • 77956407620 scopus 로고    scopus 로고
    • Hedgehog pathway activation in chronic myeloid leukemia
    • Z. Jagani, M. Dorsch, and M. Warmuth Hedgehog pathway activation in chronic myeloid leukemia Cell Cycle 9 2010 3449 3456
    • (2010) Cell Cycle , vol.9 , pp. 3449-3456
    • Jagani, Z.1    Dorsch, M.2    Warmuth, M.3
  • 130
    • 84862517728 scopus 로고    scopus 로고
    • Cancer stem cells: Current status and evolving complexities
    • J.E. Visvader, and G.J. Lindeman Cancer stem cells: current status and evolving complexities Cell Stem Cell 10 2012 717 728
    • (2012) Cell Stem Cell , vol.10 , pp. 717-728
    • Visvader, J.E.1    Lindeman, G.J.2
  • 133
    • 75149117750 scopus 로고    scopus 로고
    • Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop
    • V. Levina, A. Marrangoni, T. Wang, S. Parikh, Y. Su, R. Herberman, A. Lokshin, and E. Gorelik Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop Cancer Res. 70 2010 338 346
    • (2010) Cancer Res. , vol.70 , pp. 338-346
    • Levina, V.1    Marrangoni, A.2    Wang, T.3    Parikh, S.4    Su, Y.5    Herberman, R.6    Lokshin, A.7    Gorelik, E.8
  • 135
    • 84862740746 scopus 로고    scopus 로고
    • The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells
    • C. Huang, X.M. Zhang, R.T. Tavaluc, L.S. Hart, D.T. Dicker, W. Wang, and W.S. El-Deiry The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells Cancer Biol. Ther. 8 2009 2186 2193
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 2186-2193
    • Huang, C.1    Zhang, X.M.2    Tavaluc, R.T.3    Hart, L.S.4    Dicker, D.T.5    Wang, W.6    El-Deiry, W.S.7
  • 136
    • 84868015363 scopus 로고    scopus 로고
    • Loss of p53 exacerbates multiple myeloma phenotype by facilitating the reprogramming of hematopoietic stem/progenitor cells to malignant plasma cells by MafB
    • C. Vicente-Duenas, I. Gonzalez-Herrero, M.B. Garcia Cenador, F.J. Garcia Criado, and I. Sanchez-Garcia Loss of p53 exacerbates multiple myeloma phenotype by facilitating the reprogramming of hematopoietic stem/progenitor cells to malignant plasma cells by MafB Cell Cycle 11 2012 3896 3900
    • (2012) Cell Cycle , vol.11 , pp. 3896-3900
    • Vicente-Duenas, C.1    Gonzalez-Herrero, I.2    Garcia Cenador, M.B.3    Garcia Criado, F.J.4    Sanchez-Garcia, I.5
  • 137
    • 70349985246 scopus 로고    scopus 로고
    • Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice
    • P.P. Lin, M.K. Pandey, F. Jin, A.K. Raymond, H. Akiyama, and G. Lozano Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice Carcinogenesis 30 2009 1789 1795
    • (2009) Carcinogenesis , vol.30 , pp. 1789-1795
    • Lin, P.P.1    Pandey, M.K.2    Jin, F.3    Raymond, A.K.4    Akiyama, H.5    Lozano, G.6
  • 140
    • 0034024715 scopus 로고    scopus 로고
    • Mutation of p53 with loss of heterozygosity in the osteosarcomatous component of a dedifferentiated chondrosarcoma
    • H.J. Grote, R. Schneider-Stock, W. Neumann, and A. Roessner Mutation of p53 with loss of heterozygosity in the osteosarcomatous component of a dedifferentiated chondrosarcoma Virchows Arch. 436 2000 494 497
    • (2000) Virchows Arch. , vol.436 , pp. 494-497
    • Grote, H.J.1    Schneider-Stock, R.2    Neumann, W.3    Roessner, A.4
  • 142
    • 84880764103 scopus 로고    scopus 로고
    • "dedifferentiation" and high-grade transformation in salivary gland carcinomas
    • T. Nagao "Dedifferentiation" and high-grade transformation in salivary gland carcinomas Head Neck Pathol. 7 Suppl. 1 2013 S37 47
    • (2013) Head Neck Pathol. , vol.7 , Issue.SUPPL. 1 , pp. 37-47
    • Nagao, T.1
  • 147
    • 33745432825 scopus 로고    scopus 로고
    • How wild-type TP53 is inactivated in undifferentiated-type gastric carcinomas: Analyses of intratumoral heterogeneity in deletion and mutation of TP53
    • A. Yoshimura, H. Sugihara, Z.Q. Ling, D.F. Peng, K. Mukaisho, Y. Fujiyama, and T. Hattori How wild-type TP53 is inactivated in undifferentiated-type gastric carcinomas: analyses of intratumoral heterogeneity in deletion and mutation of TP53 Pathobiology 73 2006 40 49
    • (2006) Pathobiology , vol.73 , pp. 40-49
    • Yoshimura, A.1    Sugihara, H.2    Ling, Z.Q.3    Peng, D.F.4    Mukaisho, K.5    Fujiyama, Y.6    Hattori, T.7
  • 149
    • 26844469719 scopus 로고    scopus 로고
    • Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus
    • C.G. Eberhart, A. Chaudhry, R.W. Daniel, L. Khaki, K.V. Shah, and P.E. Gravitt Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus BMC Cancer 5 2005 19
    • (2005) BMC Cancer , vol.5 , pp. 19
    • Eberhart, C.G.1    Chaudhry, A.2    Daniel, R.W.3    Khaki, L.4    Shah, K.V.5    Gravitt, P.E.6
  • 150
    • 13144250127 scopus 로고    scopus 로고
    • P53 overexpression in small hepatocellular carcinomas containing two different histologic grades
    • Y. Nakashima, C.C. Hsia, H. Yuwen, M. Minemura, O. Nakashima, M. Kojiro, and E. Tabor p53 overexpression in small hepatocellular carcinomas containing two different histologic grades Int. J. Oncol. 12 1998 455 459
    • (1998) Int. J. Oncol. , vol.12 , pp. 455-459
    • Nakashima, Y.1    Hsia, C.C.2    Yuwen, H.3    Minemura, M.4    Nakashima, O.5    Kojiro, M.6    Tabor, E.7
  • 151
    • 0034241501 scopus 로고    scopus 로고
    • Relationship between p53 overexpression and the proliferative activity in hepatocellular carcinoma
    • T. Itoh, T. Shiro, T. Seki, T. Nakagawa, M. Wakabayashi, K. Inoue, and A. Okamura Relationship between p53 overexpression and the proliferative activity in hepatocellular carcinoma Int. J. Mol. Med. 6 2000 137 142
    • (2000) Int. J. Mol. Med. , vol.6 , pp. 137-142
    • Itoh, T.1    Shiro, T.2    Seki, T.3    Nakagawa, T.4    Wakabayashi, M.5    Inoue, K.6    Okamura, A.7


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