-
1
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangectasia
-
Kastan M, Zhan Q, El-Deiry W, Carrier F, Jacks T, Walsh W, et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangectasia. Cell 1992;71:587-97.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.1
Zhan, Q.2
El-Deiry, W.3
Carrier, F.4
Jacks, T.5
Walsh, W.6
-
2
-
-
0028294605
-
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
-
El-Deiry W, Harper J, O'Connor P, Velculescu V, Canman C, Jackman J, et al. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res 1994;54:1169-74.
-
(1994)
Cancer Res
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.1
Harper, J.2
O'Connor, P.3
Velculescu, V.4
Canman, C.5
Jackman, J.6
-
3
-
-
0032575705
-
A matter of life and death
-
Evan G, Littlewood T. A matter of life and death. Science 1998;281:1317-22.
-
(1998)
Science
, vol.281
, pp. 1317-1322
-
-
Evan, G.1
Littlewood, T.2
-
4
-
-
0028071555
-
Mutations in p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt M, Bennett W, Hollstein M, Harris C. Mutations in p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1994;54:4855-78.
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.1
Bennett, W.2
Hollstein, M.3
Harris, C.4
-
5
-
-
0029919634
-
Somatic point mutations in the p53 gene of human tumors and cell lines: Update compilation
-
Hollstein M, Shomer B, Greenblat M, Soussi T, Hovig E, Montesano R, et al. Somatic point mutations in the p53 gene of human tumors and cell lines: update compilation. Nucleic Acids Res 1996;24:141-6.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 141-146
-
-
Hollstein, M.1
Shomer, B.2
Greenblat, M.3
Soussi, T.4
Hovig, E.5
Montesano, R.6
-
6
-
-
0025639158
-
The E6 oncoprotein encoded by human papilloma virus types 16 and 18 promotes the degradation of p53
-
Scheffner MB, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papilloma virus types 16 and 18 promotes the degradation of p53. Cell 1990;63:1129-36.
-
(1990)
Cell
, vol.63
, pp. 1129-1136
-
-
Scheffner, M.B.1
Werness, B.A.2
Huibregtse, J.M.3
Levine, A.J.4
Howley, P.M.5
-
7
-
-
0030935013
-
Regulation of p53 levels by the E1B 55kD protein and E4 or E6 in adenovirus-infected cells
-
Querido E, Marcellus RC, Lai A, Charbonneau R, Teodor JG, Ketner G, et al. Regulation of p53 levels by the E1B 55kD protein and E4 or E6 in adenovirus-infected cells. J Virol 1997;71:3788-98.
-
(1997)
J Virol
, vol.71
, pp. 3788-3798
-
-
Querido, E.1
Marcellus, R.C.2
Lai, A.3
Charbonneau, R.4
Teodor, J.G.5
Ketner, G.6
-
10
-
-
0025853776
-
Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
-
Farkhazadeh SS, Trusko SP, George DL. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J 1991;10:1565-9.
-
(1991)
EMBO J
, vol.10
, pp. 1565-1569
-
-
Farkhazadeh, S.S.1
Trusko, S.P.2
George, D.L.3
-
11
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner JE, Kinzler KW, Meltzer PS, George DL, Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 1992;358:80-3.
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.E.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
12
-
-
0030028076
-
MDM2 amplification, p53 mutation, and accumulation of the p53 gene product in malignant fibrous histiocytoma
-
Reid AH, Tsai MM, Venzon DJ, Wright CF, Lack EE, O'Leary TJ. MDM2 amplification, p53 mutation, and accumulation of the p53 gene product in malignant fibrous histiocytoma. Diagn Mol Pathol 1996;5:65-73.
-
(1996)
Diagn Mol Pathol
, vol.5
, pp. 65-73
-
-
Reid, A.H.1
Tsai, M.M.2
Venzon, D.J.3
Wright, C.F.4
Lack, E.E.5
O'Leary, T.J.6
-
13
-
-
0031732740
-
MDM2 amplification and loss of heterozygosity at Rb and p53 genes: No simultaneous alterations in the oncogenesis of liposarcomas
-
Scheider-Stock T, Walter H, Radig K, Rys J, Bosse A, Kuhnen C, et al. MDM2 amplification and loss of heterozygosity at Rb and p53 genes: no simultaneous alterations in the oncogenesis of liposarcomas. J Cancer Res Clin Oncol 1998;124:532-40.
-
(1998)
J Cancer Res Clin Oncol
, vol.124
, pp. 532-540
-
-
Scheider-Stock, T.1
Walter, H.2
Radig, K.3
Rys, J.4
Bosse, A.5
Kuhnen, C.6
-
14
-
-
0030964879
-
p53 and MDM2 alterations in osteosarcomas - Correlation with clinicopathologic features and proliferative rate
-
Lonardo F, Ueda T, Huvos AG, Healey J, Ladanui M. p53 and MDM2 alterations in osteosarcomas - correlation with clinicopathologic features and proliferative rate. Cancer 1997;79: 1541-7.
-
(1997)
Cancer
, vol.79
, pp. 1541-1547
-
-
Lonardo, F.1
Ueda, T.2
Huvos, A.G.3
Healey, J.4
Ladanui, M.5
-
15
-
-
0031786826
-
Overexpression of MDM2 in acute childhood lymphoblastic leukemia
-
Gustafsson B, Stal O, Gustaffson B. Overexpression of MDM2 in acute childhood lymphoblastic leukemia. Pediatr Hematol Oncol 1998;15:519-26.
-
(1998)
Pediatr Hematol Oncol
, vol.15
, pp. 519-526
-
-
Gustafsson, B.1
Stal, O.2
Gustaffson, B.3
-
16
-
-
0029829291
-
A molecular and immunohistochemical study of the MDM2 protein isoforms and p53 gene product in bronchogenic carcinoma
-
Gorgooulis VG, Zoumpourlis V, Rassidakis GZ, Karameris A, Rassidakis AN, Spandidos DA, et al. A molecular and immunohistochemical study of the MDM2 protein isoforms and p53 gene product in bronchogenic carcinoma. J Pathol 1996; 180:129-37.
-
(1996)
J Pathol
, vol.180
, pp. 129-137
-
-
Gorgooulis, V.G.1
Zoumpourlis, V.2
Rassidakis, G.Z.3
Karameris, A.4
Rassidakis, A.N.5
Spandidos, D.A.6
-
17
-
-
0032710435
-
Oncoprotein MDM2 overexpression is associated with poor prognosis in distinct non-Hodgkin's lymphoma entities
-
Moeller MB, Nielsen O, Pedersen NT. Oncoprotein MDM2 overexpression is associated with poor prognosis in distinct non-Hodgkin's lymphoma entities. Mod Pathol 1999;12:1010-16.
-
(1999)
Mod Pathol
, vol.12
, pp. 1010-1016
-
-
Moeller, M.B.1
Nielsen, O.2
Pedersen, N.T.3
-
18
-
-
0030951971
-
Strong correlation of basement membrane degradation with p53 inactivation and/or MDM2 overexpression in superficial urothelial carcinomas
-
Özdemir E, Kakehi Y, Okuno H, Habuchi T, Okada Y, Yoshida O. Strong correlation of basement membrane degradation with p53 inactivation and/or MDM2 overexpression in superficial urothelial carcinomas. J Urol 1997;158:206-11.
-
(1997)
J Urol
, vol.158
, pp. 206-211
-
-
Özdemir, E.1
Kakehi, Y.2
Okuno, H.3
Habuchi, T.4
Okada, Y.5
Yoshida, O.6
-
19
-
-
0344287194
-
Immunohistochemical MDM2 expression in minor salivary gland tumours and its relationship to p53 gene status
-
Araujo VC, Martins MT, Leite KRM, Gomez RS, Araujo NS. Immunohistochemical MDM2 expression in minor salivary gland tumours and its relationship to p53 gene status. Oral Oncology 2000;36:67-9.
-
(2000)
Oral Oncology
, vol.36
, pp. 67-69
-
-
Araujo, V.C.1
Martins, M.T.2
Leite, K.R.M.3
Gomez, R.S.4
Araujo, N.S.5
-
20
-
-
0027331484
-
p53 protein accumulation and gene mutation in the progression of human prostate carcinoma
-
Navone N, Troncoso P, Pisters LL, Goodrow TL, Palmer JL, Nichols WW, et al. p53 protein accumulation and gene mutation in the progression of human prostate carcinoma. J Natl Cancer Inst 1993;85:1657-69.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1657-1669
-
-
Navone, N.1
Troncoso, P.2
Pisters, L.L.3
Goodrow, T.L.4
Palmer, J.L.5
Nichols, W.W.6
-
21
-
-
0027272238
-
p53 is mutated in a subset of advanced-stage prostate cancers
-
Bookstein R, MacGrogan D, Hilsenbeck SG, Sharkey F, Allred C. p53 is mutated in a subset of advanced-stage prostate cancers. Cancer Res 1993;53:3369-73.
-
(1993)
Cancer Res
, vol.53
, pp. 3369-3373
-
-
Bookstein, R.1
MacGrogan, D.2
Hilsenbeck, S.G.3
Sharkey, F.4
Allred, C.5
-
22
-
-
0026651717
-
Small subgroup of aggressive, highly proliferative prostatic carcinoma defined by p53 accumulation
-
Visakorpi T, Kallioniemi OP, Heikkinen A, Koivukla T, Isola J. Small subgroup of aggressive, highly proliferative prostatic carcinoma defined by p53 accumulation. J Natl Cancer Inst 1992;84:883-7.
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 883-887
-
-
Visakorpi, T.1
Kallioniemi, O.P.2
Heikkinen, A.3
Koivukla, T.4
Isola, J.5
-
23
-
-
0026609019
-
Expression of mutant p53 proteins in lung cancer correlates with the class of p53 mutations
-
Bodner SM, Minna JD, Jensen SM, D'amico D, Carbone D, Mitsudomi T, et al. Expression of mutant p53 proteins in lung cancer correlates with the class of p53 mutations. Oncogene 1992;7:743-9.
-
(1992)
Oncogene
, vol.7
, pp. 743-749
-
-
Bodner, S.M.1
Minna, J.D.2
Jensen, S.M.3
D'amico, D.4
Carbone, D.5
Mitsudomi, T.6
-
24
-
-
0028841050
-
The clinical significance of p53 aberrations in human tumors
-
Bosari S, Viale G. The clinical significance of p53 aberrations in human tumors. Virch Arch 1995;427:229-41.
-
(1995)
Virch Arch
, vol.427
, pp. 229-241
-
-
Bosari, S.1
Viale, G.2
-
25
-
-
0027057589
-
Monoclonal antibodies against recombinant parts of the Ki-67 antigen (Mib-1 and Mib-6) detect proliferating cells in microwave processed formalin-fixed paraffin sections
-
Cattoretti G, Becker MH, Key G, Duchrow M, Schwter C, Galle J, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (Mib-1 and Mib-6) detect proliferating cells in microwave processed formalin-fixed paraffin sections. J Pathol 1992;168:357-63.
-
(1992)
J Pathol
, vol.168
, pp. 357-363
-
-
Cattoretti, G.1
Becker, M.H.2
Key, G.3
Duchrow, M.4
Schwter, C.5
Galle, J.6
-
26
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrielli Y, Sherman Y, Ben-Sasson AS. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
-
(1992)
J Cell Biol
, vol.119
, pp. 493-501
-
-
Gavrielli, Y.1
Sherman, Y.2
Ben-Sasson, A.S.3
-
27
-
-
0026589997
-
Histologic grading of prostate cancer: A perspective
-
Gleason DF. Histologic grading of prostate cancer: a perspective. Hum Pathol 1992;23:273-9.
-
(1992)
Hum Pathol
, vol.23
, pp. 273-279
-
-
Gleason, D.F.1
-
28
-
-
0025126776
-
Intraglandular tumor extent and prognosis in prostatic carcinoma: Application of a grid method to prostatectomy specimens
-
Humphrey PA, Vollmer RT. Intraglandular tumor extent and prognosis in prostatic carcinoma: application of a grid method to prostatectomy specimens. Hum Pathol 1990;21: 799-804.
-
(1990)
Hum Pathol
, vol.21
, pp. 799-804
-
-
Humphrey, P.A.1
Vollmer, R.T.2
-
29
-
-
0026444924
-
The TNM classification of prostate carcinoma
-
Schroder FH, Hermanek P, Denis L, Fair WR, Gospodarowicz MK, Pavone-Macaluso M. The TNM classification of prostate carcinoma. Prostate 1992;4(Suppl.):129-38.
-
(1992)
Prostate
, vol.4
, Issue.SUPPL.
, pp. 129-138
-
-
Schroder, F.H.1
Hermanek, P.2
Denis, L.3
Fair, W.R.4
Gospodarowicz, M.K.5
Pavone-Macaluso, M.6
-
30
-
-
0002538655
-
Sample preparation from paraffin-embedded tissues
-
Innis M, editor. San Diego: Academic Press
-
Wright DK, Manos MM. Sample preparation from paraffin-embedded tissues. In: Innis M, editor. PCR protocols: a guide to methods and applications. San Diego: Academic Press; 1990. p. 153.
-
(1990)
PCR Protocols: A Guide to Methods and Applications
, pp. 153
-
-
Wright, D.K.1
Manos, M.M.2
-
31
-
-
0030890851
-
A rapid and nonisotopic method for the screening and sequencing of p53 gene mutations in formalin-fixed, paraffin-embedded tumors
-
Soong R, Iacopetta BJ. A rapid and nonisotopic method for the screening and sequencing of p53 gene mutations in formalin-fixed, paraffin-embedded tumors. Mod Pathol 1997;10:252-8.
-
(1997)
Mod Pathol
, vol.10
, pp. 252-258
-
-
Soong, R.1
Iacopetta, B.J.2
-
34
-
-
0000428461
-
Immunocytomicroscopy: A diagnostic tool for the surgical pathologist
-
Taylor CR, Cote RJ, editors. 2nd ed. Philadelphia: WB Saunders
-
Taylor CR, Cote RJ. Immunocytomicroscopy: a diagnostic tool for the surgical pathologist. In: Taylor CR, Cote RJ, editors. Major problems in pathology. Vol 19. 2nd ed. Philadelphia: WB Saunders; 1994. p. 421-3.
-
(1994)
Major Problems in Pathology
, vol.19
, pp. 421-423
-
-
Taylor, C.R.1
Cote, R.J.2
-
35
-
-
0030829938
-
Combined analysis with Bcl2 and p53 immunostaining predicts poorer prognosis in prostatic carcinoma
-
Matsushima H, Kitamura T, Goto T, Hosaka Y, Homma Y, Kawabe K. Combined analysis with Bcl2 and p53 immunostaining predicts poorer prognosis in prostatic carcinoma. J Urol 1997;158:2278-83.
-
(1997)
J Urol
, vol.158
, pp. 2278-2283
-
-
Matsushima, H.1
Kitamura, T.2
Goto, T.3
Hosaka, Y.4
Homma, Y.5
Kawabe, K.6
-
36
-
-
0013532876
-
Multiple mechanisms of p53 inactivation in human prostate cancer
-
Chen YQ, Gao X, Grignon D, Sakr W, Honn KV, Borders JS, et al. Multiple mechanisms of p53 inactivation in human prostate cancer. Cancer Mol Biol 1994;1:357-67.
-
(1994)
Cancer Mol Biol
, vol.1
, pp. 357-367
-
-
Chen, Y.Q.1
Gao, X.2
Grignon, D.3
Sakr, W.4
Honn, K.V.5
Borders, J.S.6
-
37
-
-
0032772364
-
Inactivation of the p53 pathway in prostate cancer: Impact on tumor progression
-
Osman I, Drobnjak M, Fazzari M, Ferrara J, Scher HI, Cordon-Cardo C. Inactivation of the p53 pathway in prostate cancer: impact on tumor progression. Clin Cancer Res 1999; 5:2082-8.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2082-2088
-
-
Osman, I.1
Drobnjak, M.2
Fazzari, M.3
Ferrara, J.4
Scher, H.I.5
Cordon-Cardo, C.6
-
39
-
-
0030988343
-
Abnormal p53 expression is rare in clinically localized human prostate cancer: Comparison between immunohistochemical and molecular detection of p53 mutations
-
Mottaz AE, Markwalder R, Fey MF, Klina I, Merz VW, Thalmann GN, et al. Abnormal p53 expression is rare in clinically localized human prostate cancer: comparison between immunohistochemical and molecular detection of p53 mutations. Prostate 1997;31:209-15.
-
(1997)
Prostate
, vol.31
, pp. 209-215
-
-
Mottaz, A.E.1
Markwalder, R.2
Fey, M.F.3
Klina, I.4
Merz, V.W.5
Thalmann, G.N.6
-
40
-
-
0028245328
-
p53 in prostate cancer: Frequent expressed transition mutations
-
Chi S-G, White RWV, Meyers FJ, Siders DB, Lee F, Gumerlock PH. p53 in prostate cancer: frequent expressed transition mutations. J Natl Cancer Inst 1994;86:926-33.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 926-933
-
-
Chi, S.-G.1
White, R.W.V.2
Meyers, F.J.3
Siders, D.B.4
Lee, F.5
Gumerlock, P.H.6
-
41
-
-
0027489384
-
Clinical implications of the p53 tumor-suppressor gene
-
Harris CC, Hollstein M. Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 1993;28:1318-27.
-
(1993)
N Engl J Med
, vol.28
, pp. 1318-1327
-
-
Harris, C.C.1
Hollstein, M.2
-
43
-
-
0030053794
-
Abnormal expression of MDM2 in breast carcinomas
-
Bueso-Ramos CE, Manshouri T, Haidar MA, Yang Y, McCown N P, Ordonez N, et al. Abnormal expression of MDM2 in breast carcinomas. Breast Cancer Res Treat 1996;37:179-88.
-
(1996)
Breast Cancer Res Treat
, vol.37
, pp. 179-188
-
-
Bueso-Ramos, C.E.1
Manshouri, T.2
Haidar, M.A.3
Yang, Y.4
McCown, N.P.5
Ordonez, N.6
-
44
-
-
0030795068
-
Translational enhancement of MDM2 oncogene expression in human tumour cells containing a stabilized wild-type p53 protein
-
Landers JE, Cassel SL, George DL. Translational enhancement of MDM2 oncogene expression in human tumour cells containing a stabilized wild-type p53 protein. Cancer Res 1997;57:3562-8.
-
(1997)
Cancer Res
, vol.57
, pp. 3562-3568
-
-
Landers, J.E.1
Cassel, S.L.2
George, D.L.3
-
45
-
-
0028081261
-
The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low grade lymphoma of B cell origin
-
Watanabe T, Hootta T, Ichikawa A, Kinoshita T, Nagai H, Uchida T. The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low grade lymphoma of B cell origin. Blood 1994;44:3158-65.
-
(1994)
Blood
, vol.44
, pp. 3158-3165
-
-
Watanabe, T.1
Hootta, T.2
Ichikawa, A.3
Kinoshita, T.4
Nagai, H.5
Uchida, T.6
-
46
-
-
0028074536
-
Alterations in the p53 and MDM2 genes are infrequent in clinically localized, stage B prostate adenocarcinomas
-
Ittmann M, Wieczorek R, Heller P, Dave A, Provet J, Krolewski J. Alterations in the p53 and MDM2 genes are infrequent in clinically localized, stage B prostate adenocarcinomas. Am J Pathol 1994;1994:287-93.
-
(1994)
Am J Pathol
, vol.1994
, pp. 287-293
-
-
Ittmann, M.1
Wieczorek, R.2
Heller, P.3
Dave, A.4
Provet, J.5
Krolewski, J.6
-
47
-
-
0029028354
-
Interaction between the retinoblastoma protein and the oncoprotein MDM2
-
Xiao Z, Cheen J, Levine AJ, Modjtajedi N, Xing JS, Sellers WR, et al. Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature 1995;375:694-8.
-
(1995)
Nature
, vol.375
, pp. 694-698
-
-
Xiao, Z.1
Cheen, J.2
Levine, A.J.3
Modjtajedi, N.4
Xing, J.S.5
Sellers, W.R.6
-
48
-
-
0032545222
-
p53 independent role of MDM2 in TGF-β1 resistance
-
Sunn P, Dong P, Dal K, Dannon GJ, Beach D. p53 independent role of MDM2 in TGF-β1 resistance. Science 1998;282: 2270-2.
-
(1998)
Science
, vol.282
, pp. 2270-2272
-
-
Sunn, P.1
Dong, P.2
Dal, K.3
Dannon, G.J.4
Beach, D.5
-
49
-
-
0027174951
-
p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes
-
Marchetti A, Buttitta F, Merlo G, Diella F, Pellegrini S, Pepe S, et al. p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes. Cancer Res 1993;53:2846-51.
-
(1993)
Cancer Res
, vol.53
, pp. 2846-2851
-
-
Marchetti, A.1
Buttitta, F.2
Merlo, G.3
Diella, F.4
Pellegrini, S.5
Pepe, S.6
|