Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells

Carcinogenesis

Volumn 32, Issue 11, 2011, Pages 1597-1606

  Motohara, Takeshi ^a,b   Masuko, Sachiko ^a   Ishimoto, Takatsugu ^a   Yae, Toshifumi ^a   Onishi, Nobuyuki ^a   Muraguchi, Teruyuki ^c   Hirao, Atsushi ^c   Matsuzaki, Yumi ^a   Tashiro, Hironori ^b   Katabuchi, Hidetaka ^b   Saya, Hideyuki ^a,d   Nagano, Osamu ^a,d  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 8; EPITHELIAL CELL ADHESION MOLECULE; PROTEIN P53; RETROVIRUS VECTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER STEM CELL; CELL EXPANSION; CONTROLLED STUDY; GENETIC TRANSDUCTION; MOUSE; NONHUMAN; ONCOGENE C MYC; ONCOGENE K RAS; OVARY CELL; PERITONEUM METASTASIS; PRIORITY JOURNAL; PROGENY; PROTEIN DEPLETION; RNA INTERFERENCE; STEM CELL; STEM CELL EXPANSION; TUMOR GROWTH;

ANIMALS; ANTIGENS, NEOPLASM; APOPTOSIS; BLOTTING, WESTERN; CELL ADHESION; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; FLOW CYTOMETRY; IMMUNOENZYME TECHNIQUES; MICE; MICE, INBRED C57BL; NEOPLASTIC STEM CELLS; OVARIAN NEOPLASMS; OVARY; PERITONEAL NEOPLASMS; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENE PROTEINS P21(RAS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 80755187837     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr183     Document Type: Article

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