-
1
-
-
34547660321
-
A spatially and temporally restricted mouse model of soft tissue sarcoma
-
Kirsch,D.G. et al. (2007) A spatially and temporally restricted mouse model of soft tissue sarcoma. Nat. Med., 13, 992-997.
-
(2007)
Nat. Med
, vol.13
, pp. 992-997
-
-
Kirsch, D.G.1
-
2
-
-
0038312141
-
Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase
-
Sommer,G. et al. (2003) Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase. Proc. Natl Acad. Sci. USA, 100, 6706-6711.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 6706-6711
-
-
Sommer, G.1
-
3
-
-
23044467277
-
A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E
-
Rubin,B.P. et al. (2005) A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E. Cancer Res., 65, 6631-6639.
-
(2005)
Cancer Res
, vol.65
, pp. 6631-6639
-
-
Rubin, B.P.1
-
4
-
-
38949125814
-
A mouse model of a human multiple GIST family with KIT-Asp820Tyr mutation generated by a knock-in strategy
-
Nakai,N. et al. (2008) A mouse model of a human multiple GIST family with KIT-Asp820Tyr mutation generated by a knock-in strategy. J. Pathol., 214, 302-311.
-
(2008)
J. Pathol
, vol.214
, pp. 302-311
-
-
Nakai, N.1
-
5
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
Jacks,T. et al. (1994) Tumor spectrum analysis in p53-mutant mice. Curr. Biol., 4, 1-7.
-
(1994)
Curr. Biol
, vol.4
, pp. 1-7
-
-
Jacks, T.1
-
6
-
-
0030265337
-
The p53-deficient mouse: A model for basic and applied cancer studies
-
Donehower,L.A. (1996) The p53-deficient mouse: A model for basic and applied cancer studies. Semin. Cancer Biol., 7, 269-278.
-
(1996)
Semin. Cancer Biol
, vol.7
, pp. 269-278
-
-
Donehower, L.A.1
-
7
-
-
0023715595
-
A cancer family syndrome in twenty-four kindreds
-
Li,F.P. et al. (1988) A cancer family syndrome in twenty-four kindreds. Cancer Res., 48, 5358-5362.
-
(1988)
Cancer Res
, vol.48
, pp. 5358-5362
-
-
Li, F.P.1
-
8
-
-
0026702996
-
-
Effects of an Rb mutation in the mouse, see comments
-
Jacks,T. et al. (1992) Effects of an Rb mutation in the mouse. Nature, 359, 295-300[see comments].
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
-
9
-
-
0026744563
-
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis, see comment
-
Lee,E.Y. et al. (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature, 359 288-294[see comment].
-
(1992)
Nature
, vol.359
, pp. 288-294
-
-
Lee, E.Y.1
-
10
-
-
0026760426
-
-
Requirement for a functional Rb-1 gene in murine development, see comment
-
Clarke,A.R. et al. (1992) Requirement for a functional Rb-1 gene in murine development. Nature, 359, 328-330[see comment].
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.R.1
-
11
-
-
0022623369
-
Second primary neoplasms in patients with retinoblastoma
-
Draper,G.J. et al. (1986) Second primary neoplasms in patients with retinoblastoma. Br. J. Cancer, 53, 661-671.
-
(1986)
Br. J. Cancer
, vol.53
, pp. 661-671
-
-
Draper, G.J.1
-
12
-
-
0028174064
-
Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance
-
Hu,N. et al. (1994) Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance. Oncogene, 9, 1021-1027.
-
(1994)
Oncogene
, vol.9
, pp. 1021-1027
-
-
Hu, N.1
-
13
-
-
0034656212
-
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
-
Marino,S. et al. (2000) Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev., 14, 994-1004.
-
(2000)
Genes Dev
, vol.14
, pp. 994-1004
-
-
Marino, S.1
-
14
-
-
0034084930
-
Identification of a prx1 limb enhancer
-
Martin,J.F. et al. (2000) Identification of a prx1 limb enhancer. Genesis J. Genet. Dev., 26, 225-229.
-
(2000)
Genesis J. Genet. Dev
, vol.26
, pp. 225-229
-
-
Martin, J.F.1
-
15
-
-
0036076389
-
Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer
-
Logan,M. et al. (2002) Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis J. Genet. Dev., 33, 77-80.
-
(2002)
Genesis J. Genet. Dev
, vol.33
, pp. 77-80
-
-
Logan, M.1
-
16
-
-
38549157655
-
Osteoblast-targeted expression of Sfrp4 in mice results in low bone mass
-
Nakanishi,R. et al. (2008) Osteoblast-targeted expression of Sfrp4 in mice results in low bone mass. J. Bone Miner. Res., 23, 271-277.
-
(2008)
J. Bone Miner. Res
, vol.23
, pp. 271-277
-
-
Nakanishi, R.1
-
17
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano,P. (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet., 21, 70-71.
-
(1999)
Nat. Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
18
-
-
4444246433
-
Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity
-
Zamurovic,N. et al. (2004) Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity. J. Biol. Chem., 279, 37704-37715.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 37704-37715
-
-
Zamurovic, N.1
-
19
-
-
33644879150
-
Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling
-
Lengner,C.J. et al. (2006) Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling. J. Cell Biol., 172, 909-921.
-
(2006)
J. Cell Biol
, vol.172
, pp. 909-921
-
-
Lengner, C.J.1
-
20
-
-
50149110590
-
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
-
Berman,S.D. et al. (2008) Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc. Natl Acad. Sci. USA, 105, 11851-11856.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 11851-11856
-
-
Berman, S.D.1
-
21
-
-
45349086509
-
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease
-
Walkley,C.R. et al. (2008) Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes Dev., 22, 1662-1676.
-
(2008)
Genes Dev
, vol.22
, pp. 1662-1676
-
-
Walkley, C.R.1
-
22
-
-
2942548981
-
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression
-
Stein,G.S. et al. (2004) Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression. Oncogene, 23, 4315-4329.
-
(2004)
Oncogene
, vol.23
, pp. 4315-4329
-
-
Stein, G.S.1
-
23
-
-
20144371011
-
The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts
-
Galindo,M. et al. (2005) The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts. J. Biol. Chem., 280 20274-20285.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 20274-20285
-
-
Galindo, M.1
-
24
-
-
0026471778
-
MHox: A mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer
-
Cserjesi,P. et al. (1992) MHox: A mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer. Development, 115, 1087-1101.
-
(1992)
Development
, vol.115
, pp. 1087-1101
-
-
Cserjesi, P.1
-
25
-
-
0029086672
-
Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain
-
Leussink,B. et al. (1995) Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain. Mech. Dev., 52, 51-64.
-
(1995)
Mech. Dev
, vol.52
, pp. 51-64
-
-
Leussink, B.1
-
26
-
-
0015043748
-
-
Knudson,A.G.Jr (1971) Mutation and cancer: Statistical study of retinoblastoma. Proc. Natl Acad. Sci. USA, 68, 820-823.
-
Knudson,A.G.Jr (1971) Mutation and cancer: Statistical study of retinoblastoma. Proc. Natl Acad. Sci. USA, 68, 820-823.
-
-
-
-
27
-
-
53349141349
-
The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development
-
Berman,S.D. et al. (2008) The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development. Mol. Cancer Res., 6, 1440-1451.
-
(2008)
Mol. Cancer Res
, vol.6
, pp. 1440-1451
-
-
Berman, S.D.1
-
28
-
-
57449095858
-
Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice
-
Gutierrez,G.M. et al. (2008) Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice. Proc. Natl Acad. Sci. USA, 105, 18402-18407.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 18402-18407
-
-
Gutierrez, G.M.1
|