P53 regulates cell cycle and micrornas to promote differentiation of human embryonic stem cells

PLoS Biology

Volumn 10, Issue 2, 2012, Pages

  Jain, Abhinav K ^a   Allton, Kendra ^a   Iacovino, Michelina ^b   Mahen, Elisabeth ^b   Milczarek, Robert J ^c   Zwaka, Thomas P ^c   Kyba, Michael ^b   Barton, Michelle Craig ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c CENTER FOR CELL AND GENE THERAPY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; HISTONE ACETYLTRANSFERASE PCAF; KRUPPEL LIKE FACTOR 4; LYSINE; MICRORNA; MICRORNA 145; MICRORNA 34A; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN LIN28A; PROTEIN MDM2; PROTEIN P53; PROTEIN TRIM24; RETINOIC ACID; STEM CELL FACTOR; TRANSCRIPTION FACTOR SOX2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; DIFFERENTIATION ANTIGEN; MIRN145 MICRORNA, HUMAN; MIRN34 MICRORNA, HUMAN; TP53 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RNA INTERFERENCE; ACETYLATION; APOPTOSIS; BINDING SITE; CELL CULTURE; CELL CYCLE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROMOTER REGION; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN STABILITY;

ACETYLATION; ANTIGENS, DIFFERENTIATION; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL CYCLE; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; TRANSCRIPTION, GENETIC; TRETINOIN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84857483281     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001268     Document Type: Article

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