Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo

Cancer Research

Volumn 70, Issue 10, 2010, Pages 4185-4194

  Rubio, Ruth ^a   García Castro, Javier ^a,b   Gutiérrez Aranda, Iván ^a   Paramio, Jesús ^c   Santos, Mirentxu ^c   Catalina, Purificación ^a   Leone, Paola E ^a   Menendez, Pablo ^a   Rodríguez, René ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c CIEMAT   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; RETINOBLASTOMA PROTEIN;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL TRANSFORMATION; GENE EXPRESSION; LEIOMYOSARCOMA; MALIGNANT TRANSFORMATION; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SMOOTH MUSCLE;

ANIMALS; BLOTTING, WESTERN; CELL ADHESION; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; FLUORESCENT ANTIBODY TECHNIQUE; INTEGRASES; LEIOMYOSARCOMA; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SARCOMA, EXPERIMENTAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77952804351     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-4640     Document Type: Article

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