Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency

American Journal of Pathology

Volumn 179, Issue 4, 2011, Pages 1616-1622

  Van Boxtel, Ruben ^a   Kuiper, Raoul V ^b   Toonen, Pim W ^a   Van Heesch, Sebastiaan ^a   Hermsen, Roel ^a   De Bruin, Alain ^b   Cuppen, Edwin ^a,c  

^a HUBRECHT INSTITUTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c Center Utrecht   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; FEMALE; GENOTOXICITY; HETEROZYGOSITY; HOMOZYGOSITY; LUNG METASTASIS; MALE; MOLECULAR BIOLOGY; MORBIDITY; MUTAGENESIS; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SARCOMA;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GENE KNOCKOUT TECHNIQUES; GENOME; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM METASTASIS; RATS; RATS, MUTANT STRAINS; SARCOMA; SURVIVAL ANALYSIS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 80053266411     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.06.036     Document Type: Article

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