-
1
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden, K.H. and Prives, C. (2009) Blinded by the light: The growing complexity of p53. Cell, 137, 413-431
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
2
-
-
80052995658
-
P53, Stem Cells, and Reprogramming: Tumor suppression beyond guarding the genome
-
Spike, B.T. and Wahl, G.M. (2011) p53, Stem Cells, and Reprogramming: Tumor suppression beyond guarding the genome. Genes Cancer, 2, 404-419
-
(2011)
Genes Cancer
, vol.2
, pp. 404-419
-
-
Spike, B.T.1
Wahl, G.M.2
-
3
-
-
13944273471
-
P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
-
Lin, T., Chao, C., Saito, S., Mazur, S.J., Murphy, M.E., Appella, E. and Xu, Y. (2005) p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat. Cell. Biol., 7, 165-171
-
(2005)
Nat. Cell. Biol
, vol.7
, pp. 165-171
-
-
Lin, T.1
Chao, C.2
Saito, S.3
Mazur, S.J.4
Murphy, M.E.5
Appella, E.6
Xu, Y.7
-
4
-
-
32244436592
-
P53 suppresses the self-renewal of adult neural stem cells
-
Meletis, K., Wirta, V., Hede, S.M., Nister, M., Lundeberg, J. and Frisen, J. (2006) p53 suppresses the self-renewal of adult neural stem cells. Development, 133, 363-369
-
(2006)
Development
, vol.133
, pp. 363-369
-
-
Meletis, K.1
Wirta, V.2
Hede, S.M.3
Nister, M.4
Lundeberg, J.5
Frisen, J.6
-
5
-
-
84857483281
-
P53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells
-
Jain, A.K., Allton, K., Iacovino, M., Mahen, E., Milczarek, R.J., Zwaka, T.P., Kyba, M. and Barton, M.C. (2012) p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells. PLoS Biol., 10, e1001268
-
(2012)
PLoS Biol
, vol.10
-
-
Jain, A.K.1
Allton, K.2
Iacovino, M.3
Mahen, E.4
Milczarek, R.J.5
Zwaka, T.P.6
Kyba, M.7
Barton, M.C.8
-
6
-
-
78651100119
-
Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures
-
Mizuno, H., Spike, B.T., Wahl, G.M. and Levine, A.J. (2010) Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures. Proc. Natl Acad. Sci. USA, 107, 22745-22750
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 22745-22750
-
-
Mizuno, H.1
Spike, B.T.2
Wahl, G.M.3
Levine, A.J.4
-
7
-
-
77954464666
-
P53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal
-
Zhao, Z., Zuber, J., Diaz-Flores, E., Lintault, L., Kogan, S.C., Shannon, K. and Lowe, S.W. (2010) p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal. Genes Dev., 24, 1389-1402
-
(2010)
Genes Dev
, vol.24
, pp. 1389-1402
-
-
Zhao, Z.1
Zuber, J.2
Diaz-Flores, E.3
Lintault, L.4
Kogan, S.C.5
Shannon, K.6
Lowe, S.W.7
-
8
-
-
82255191954
-
Embryonic stem cell-specific signatures in cancer: Insights into genomic regulatory networks and implications for medicine
-
Kim, J. and Orkin, S.H. (2011) Embryonic stem cell-specific signatures in cancer: Insights into genomic regulatory networks and implications for medicine. Genome Med., 3, 75
-
(2011)
Genome Med
, vol.3
, pp. 75
-
-
Kim, J.1
Orkin, S.H.2
-
9
-
-
77955363995
-
TP53 mutations in human cancers: Origins, consequences, and clinical use
-
Olivier, M., Hollstein, M. and Hainaut, P. (2010) TP53 mutations in human cancers: Origins, consequences, and clinical use. Cold Spring Harb. Perspect. Biol., 2, a001008
-
(2010)
Cold Spring Harb. Perspect. Biol
, vol.2
-
-
Olivier, M.1
Hollstein, M.2
Hainaut, P.3
-
10
-
-
77958481889
-
P53: Guardian of reprogramming
-
Menendez, S., Camus, S. and Izpisua Belmonte, J.C. (2010) p53: Guardian of reprogramming. Cell Cycle, 9, 3887-3891
-
(2010)
Cell Cycle
, vol.9
, pp. 3887-3891
-
-
Menendez, S.1
Camus, S.2
Izpisua Belmonte, J.C.3
-
11
-
-
69349098834
-
Stem cells: The promises and perils of p53
-
Krizhanovsky, V. and Lowe, S.W. (2009) Stem cells: The promises and perils of p53. Nature, 460, 1085-1086
-
(2009)
Nature
, vol.460
, pp. 1085-1086
-
-
Krizhanovsky, V.1
Lowe, S.W.2
-
12
-
-
71449109765
-
Direct cell reprogramming is a stochastic process amenable to acceleration
-
Hanna, J., Saha, K., Pando, B., van Zon, J., Lengner, C.J., Creyghton, M.P., van Oudenaarden, A. and Jaenisch, R. (2009) Direct cell reprogramming is a stochastic process amenable to acceleration. Nature, 462, 595-601
-
(2009)
Nature
, vol.462
, pp. 595-601
-
-
Hanna, J.1
Saha, K.2
Pando, B.3
Van Zon, J.4
Lengner, C.J.5
Creyghton, M.P.6
Van Oudenaarden, A.7
Jaenisch, R.8
-
13
-
-
77954100084
-
Transposable elements have rewired the core regulatory network of human embryonic stem cells
-
Kunarso, G., Chia, N.Y., Jeyakani, J., Hwang, C., Lu, X., Chan, Y.S., Ng, H.H. and Bourque, G. (2010) Transposable elements have rewired the core regulatory network of human embryonic stem cells. Nat. Genet., 42, 631-634
-
(2010)
Nat. Genet
, vol.42
, pp. 631-634
-
-
Kunarso, G.1
Chia, N.Y.2
Jeyakani, J.3
Hwang, C.4
Lu, X.5
Chan, Y.S.6
Ng, H.H.7
Bourque, G.8
-
14
-
-
13744252631
-
Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state
-
Wei, C.L., Miura, T., Robson, P., Lim, S.K., Xu, X.Q., Lee, M.Y., Gupta, S., Stanton, L., Luo, Y., Schmitt, J. et al. (2005) Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. Stem Cells, 23, 166-185
-
(2005)
Stem Cells
, vol.23
, pp. 166-185
-
-
Wei, C.L.1
Miura, T.2
Robson, P.3
Lim, S.K.4
Xu, X.Q.5
Lee, M.Y.6
Gupta, S.7
Stanton, L.8
Luo, Y.9
Schmitt, J.10
-
15
-
-
84864517350
-
Gap 1 phase length and mouse embryonic stem cell self-renewal
-
Li, V.C., Ballabeni, A. and Kirschner, M.W. (2012) Gap 1 phase length and mouse embryonic stem cell self-renewal. Proc. Natl Acad. Sci. USA, 109, 12550-12555
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 12550-12555
-
-
Li, V.C.1
Ballabeni, A.2
Kirschner, M.W.3
-
16
-
-
34447528757
-
New cell lines from mouse epiblast share defining features with human embryonic stem cells
-
Tesar, P.J., Chenoweth, J.G., Brook, F.A., Davies, T.J., Evans, E.P., Mack, D.L., Gardner, R.L. and McKay, R.D. (2007) New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature, 448, 196-199
-
(2007)
Nature
, vol.448
, pp. 196-199
-
-
Tesar, P.J.1
Chenoweth, J.G.2
Brook, F.A.3
Davies, T.J.4
Evans, E.P.5
Mack, D.L.6
Gardner, R.L.7
McKay, R.D.8
-
17
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
Lee, T.I., Jenner, R.G., Boyer, L.A., Guenther, M.G., Levine, S.S., Kumar, R.M., Chevalier, B., Johnstone, S.E., Cole, M.F., Isono, K. et al. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell, 125, 301-313
-
(2006)
Cell
, vol.125
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
Guenther, M.G.4
Levine, S.S.5
Kumar, R.M.6
Chevalier, B.7
Johnstone, S.E.8
Cole, M.F.9
Isono, K.10
-
18
-
-
79952660821
-
Control of the embryonic stem cell state
-
Young, R.A. (2011) Control of the embryonic stem cell state. Cell, 144, 940-954
-
(2011)
Cell
, vol.144
, pp. 940-954
-
-
Young, R.A.1
-
19
-
-
53849146020
-
Model-based analysis of ChIP-Seq (MACS)
-
Zhang, Y., Liu, T., Meyer, C.A., Eeckhoute, J., Johnson, D.S., Bernstein, B.E., Nusbaum, C., Myers, R.M., Brown, M., Li, W. et al. (2008) Model-based analysis of ChIP-Seq (MACS). Genome Biol., 9, R137
-
(2008)
Genome Biol
, vol.9
-
-
Zhang, Y.1
Liu, T.2
Meyer, C.A.3
Eeckhoute, J.4
Johnson, D.S.5
Bernstein, B.E.6
Nusbaum, C.7
Myers, R.M.8
Brown, M.9
Li, W.10
-
20
-
-
70349871718
-
CEAS: Cisregulatory element annotation system
-
Shin, H., Liu, T., Manrai, A.K. and Liu, X.S. (2009) CEAS: Cisregulatory element annotation system. Bioinformatics, 25, 2605-2606
-
(2009)
Bioinformatics
, vol.25
, pp. 2605-2606
-
-
Shin, H.1
Liu, T.2
Manrai, A.K.3
Liu, X.S.4
-
21
-
-
79958117256
-
MEME-ChIP: Motif analysis of large DNA datasets
-
Machanick, P. and Bailey, T.L. (2011) MEME-ChIP: Motif analysis of large DNA datasets. Bioinformatics, 27, 1696-1697
-
(2011)
Bioinformatics
, vol.27
, pp. 1696-1697
-
-
Machanick, P.1
Bailey, T.L.2
-
22
-
-
77950529946
-
Motif Enrichment Analysis: A unified framework and an evaluation on ChIP data
-
McLeay, R.C. and Bailey, T.L. (2010) Motif Enrichment Analysis: A unified framework and an evaluation on ChIP data. BMC Bioinformatics, 11, 165
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 165
-
-
McLeay, R.C.1
Bailey, T.L.2
-
23
-
-
79952769989
-
In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development
-
Klisch, T.J., Xi, Y., Flora, A., Wang, L., Li, W. and Zoghbi, H.Y. (2011) In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development. Proc. Natl Acad. Sci. USA, 108, 3288-3293
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3288-3293
-
-
Klisch, T.J.1
Xi, Y.2
Flora, A.3
Wang, L.4
Li, W.5
Zoghbi, H.Y.6
-
24
-
-
41349115432
-
The DAVID Gene Functional Classification Tool: A novel biological module-centric algorithm to functionally analyze large gene lists
-
Huang da, W., Sherman, B.T., Tan, Q., Collins, J.R., Alvord, W.G., Roayaei, J., Stephens, R., Baseler, M.W., Lane, H.C. and Lempicki, R.A. (2007) The DAVID Gene Functional Classification Tool: A novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biol., 8, R183
-
(2007)
Genome Biol
, vol.8
-
-
Huang Da, W.1
Sherman, B.T.2
Tan, Q.3
Collins, J.R.4
Alvord, W.G.5
Roayaei, J.6
Stephens, R.7
Baseler, M.W.8
Lane, H.C.9
Lempicki, R.A.10
-
25
-
-
77952214662
-
GREAT improves functional interpretation of cis-regulatory regions
-
McLean, C.Y., Bristor, D., Hiller, M., Clarke, S.L., Schaar, B.T., Lowe, C.B., Wenger, A.M. and Bejerano, G. (2010) GREAT improves functional interpretation of cis-regulatory regions. Nat. Biotechnol., 28, 495-501
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 495-501
-
-
McLean, C.Y.1
Bristor, D.2
Hiller, M.3
Clarke, S.L.4
Schaar, B.T.5
Lowe, C.B.6
Wenger, A.M.7
Bejerano, G.8
-
26
-
-
69649109364
-
Circos: An information aesthetic for comparative genomics
-
Krzywinski, M., Schein, J., Birol, I., Connors, J., Gascoyne, R., Horsman, D., Jones, S.J. and Marra, M.A. (2009) Circos: An information aesthetic for comparative genomics. Genome Res., 19, 1639-1645
-
(2009)
Genome Res
, vol.19
, pp. 1639-1645
-
-
Krzywinski, M.1
Schein, J.2
Birol, I.3
Connors, J.4
Gascoyne, R.5
Horsman, D.6
Jones, S.J.7
Marra, M.A.8
-
27
-
-
79955550445
-
A user's guide to the encyclopedia of DNA elements (ENCODE
-
Myers, R.M., Stamatoyannopoulos, J., Snyder, M., Dunham, I., Hardison, R.C., Bernstein, B.E., Gingeras, T.R., Kent, W.J., Birney, E., Wold, B. et al. (2011) A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol., 9, e1001046
-
(2011)
PLoS Biol
, vol.9
-
-
Myers, R.M.1
Stamatoyannopoulos, J.2
Snyder, M.3
Dunham, I.4
Hardison, R.C.5
Bernstein, B.E.6
Gingeras, T.R.7
Kent, W.J.8
Birney, E.9
Wold, B.10
-
28
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry, R.A., Hobbs, B., Collin, F., Beazer-Barclay, Y.D., Antonellis, K.J., Scherf, U. and Speed, T.P. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics, 4, 249-264
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
Hobbs, B.2
Collin, F.3
Beazer-Barclay, Y.D.4
Antonellis, K.J.5
Scherf, U.6
Speed, T.P.7
-
29
-
-
67650895889
-
Trim24 targets endogenous p53 for degradation
-
Allton, K., Jain, A.K., Herz, H.M., Tsai, W.W., Jung, S.Y., Qin, J., Bergmann, A., Johnson, R.L. and Barton, M.C. (2009) Trim24 targets endogenous p53 for degradation. Proc. Natl Acad. Sci. USA, 106, 11612-11616
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 11612-11616
-
-
Allton, K.1
Jain, A.K.2
Herz, H.M.3
Tsai, W.W.4
Jung, S.Y.5
Qin, J.6
Bergmann, A.7
Johnson, R.L.8
Barton, M.C.9
-
30
-
-
0035019156
-
Loss of HCF-1- chromatin association precedes temperature-induced growth arrest of tsBN67 cells
-
Wysocka, J., Reilly, P.T. and Herr, W. (2001) Loss of HCF-1- chromatin association precedes temperature-induced growth arrest of tsBN67 cells. Mol. Cell. Biol., 21, 3820-3829
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 3820-3829
-
-
Wysocka, J.1
Reilly, P.T.2
Herr, W.3
-
31
-
-
68149144367
-
High-resolution analysis of epigenetic changes associated with X inactivation
-
Marks, H., Chow, J.C., Denissov, S., Francoijs, K.J., Brockdorff, N., Heard, E. and Stunnenberg, H.G. (2009) High-resolution analysis of epigenetic changes associated with X inactivation. Genome Res., 19, 1361-1373
-
(2009)
Genome Res
, vol.19
, pp. 1361-1373
-
-
Marks, H.1
Chow, J.C.2
Denissov, S.3
Francoijs, K.J.4
Brockdorff, N.5
Heard, E.6
Stunnenberg, H.G.7
-
32
-
-
34249818182
-
Tissue-specific transcriptional regulation has diverged significantly between human and mouse
-
Odom, D.T., Dowell, R.D., Jacobsen, E.S., Gordon, W., Danford, T.W., MacIsaac, K.D., Rolfe, P.A., Conboy, C.M., Gifford, D.K. and Fraenkel, E. (2007) Tissue-specific transcriptional regulation has diverged significantly between human and mouse. Nat. Genet., 39, 730-732
-
(2007)
Nat. Genet
, vol.39
, pp. 730-732
-
-
Odom, D.T.1
Dowell, R.D.2
Jacobsen, E.S.3
Gordon, W.4
Danford, T.W.5
MacIsaac, K.D.6
Rolfe, P.A.7
Conboy, C.M.8
Gifford, D.K.9
Fraenkel, E.10
-
34
-
-
78649646015
-
Retinoids regulate stem cell differentiation
-
Gudas, L.J. and Wagner, J.A. (2011) Retinoids regulate stem cell differentiation. J. Cell Physiol., 226, 322-330
-
(2011)
J. Cell Physiol
, vol.226
, pp. 322-330
-
-
Gudas, L.J.1
Wagner, J.A.2
-
35
-
-
0034141791
-
Functions of LIM-homeobox genes
-
Hobert, O. and Westphal, H. (2000) Functions of LIM-homeobox genes. Trends Genet., 16, 75-83
-
(2000)
Trends Genet
, vol.16
, pp. 75-83
-
-
Hobert, O.1
Westphal, H.2
-
36
-
-
0037866671
-
Fox's in development and disease
-
Lehmann, O.J., Sowden, J.C., Carlsson, P., Jordan, T. and Bhattacharya, S.S. (2003) Fox's in development and disease. Trends Genet., 19, 339-344
-
(2003)
Trends Genet
, vol.19
, pp. 339-344
-
-
Lehmann, O.J.1
Sowden, J.C.2
Carlsson, P.3
Jordan, T.4
Bhattacharya, S.S.5
-
37
-
-
0036696817
-
Twenty pairs of sox: Extent homology, and nomenclature of the mouse and human sox transcription factor gene families
-
Schepers, G.E., Teasdale, R.D. and Koopman, P. (2002) Twenty pairs of sox: Extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. Dev. Cell, 3, 167-170
-
(2002)
Dev. Cell
, vol.3
, pp. 167-170
-
-
Schepers, G.E.1
Teasdale, R.D.2
Koopman, P.3
-
38
-
-
34247332335
-
Emerging roles for zic genes in early development
-
Merzdorf, C.S. (2007) Emerging roles for zic genes in early development. Dev. Dyn., 236, 922-940
-
(2007)
Dev. Dyn
, vol.236
, pp. 922-940
-
-
Merzdorf, C.S.1
-
39
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B.E., Mikkelsen, T.S., Xie, X., Kamal, M., Huebert, D.J., Cuff, J., Fry, B., Meissner, A., Wernig, M., Plath, K. et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell, 125, 315-326
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
40
-
-
80052490840
-
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
-
Zhang, X., Yalcin, S., Lee, D.F., Yeh, T.Y., Lee, S.M., Su, J., Mungamuri, S.K., Rimmele, P., Kennedy, M., Sellers, R. et al. (2011) FOXO1 is an essential regulator of pluripotency in human embryonic stem cells. Nat. Cell. Biol., 13, 1092-1099
-
(2011)
Nat. Cell. Biol
, vol.13
, pp. 1092-1099
-
-
Zhang, X.1
Yalcin, S.2
Lee, D.F.3
Yeh, T.Y.4
Lee, S.M.5
Su, J.6
Mungamuri, S.K.7
Rimmele, P.8
Kennedy, M.9
Sellers, R.10
-
41
-
-
32644441129
-
Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6
-
Matsumoto, N., Kubo, A., Liu, H., Akita, K., Laub, F., Ramirez, F., Keller, G. and Friedman, S.L. (2006) Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6. Blood, 107, 1357-1365
-
(2006)
Blood
, vol.107
, pp. 1357-1365
-
-
Matsumoto, N.1
Kubo, A.2
Liu, H.3
Akita, K.4
Laub, F.5
Ramirez, F.6
Keller, G.7
Friedman, S.L.8
-
42
-
-
4544358659
-
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development
-
Chang, S., McKinsey, T.A., Zhang, C.L., Richardson, J.A., Hill, J.A. and Olson, E.N. (2004) Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development. Mol. Cell. Biol., 24, 8467-8476
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 8467-8476
-
-
Chang, S.1
McKinsey, T.A.2
Zhang, C.L.3
Richardson, J.A.4
Hill, J.A.5
Olson, E.N.6
-
43
-
-
0041689966
-
Targeted deletion reveals an essential function for the telomere length regulator Trf1
-
Karlseder, J., Kachatrian, L., Takai, H., Mercer, K., Hingorani, S., Jacks, T. and de Lange, T. (2003) Targeted deletion reveals an essential function for the telomere length regulator Trf1. Mol. Cell. Biol., 23, 6533-6541
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 6533-6541
-
-
Karlseder, J.1
Kachatrian, L.2
Takai, H.3
Mercer, K.4
Hingorani, S.5
Jacks, T.6
De Lange, T.7
-
44
-
-
35148867907
-
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
-
Agger, K., Cloos, P.A., Christensen, J., Pasini, D., Rose, S., Rappsilber, J., Issaeva, I., Canaani, E., Salcini, A.E. and Helin, K. (2007) UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature, 449, 731-734
-
(2007)
Nature
, vol.449
, pp. 731-734
-
-
Agger, K.1
Cloos, P.A.2
Christensen, J.3
Pasini, D.4
Rose, S.5
Rappsilber, J.6
Issaeva, I.7
Canaani, E.8
Salcini, A.E.9
Helin, K.10
-
45
-
-
36749082438
-
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
-
Hong, S., Cho, Y.W., Yu, L.R., Yu, H., Veenstra, T.D. and Ge, K. (2007) Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proc. Natl Acad. Sci. USA, 104, 18439-18444
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 18439-18444
-
-
Hong, S.1
Cho, Y.W.2
Yu, L.R.3
Yu, H.4
Veenstra, T.D.5
Ge, K.6
-
46
-
-
84864663969
-
X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner
-
Welstead, G.G., Creyghton, M.P., Bilodeau, S., Cheng, A.W., Markoulaki, S., Young, R.A. and Jaenisch, R. (2012) X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner. Proc. Natl Acad. Sci. USA, 109, 13004-13009
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 13004-13009
-
-
Welstead, G.G.1
Creyghton, M.P.2
Bilodeau, S.3
Cheng, A.W.4
Markoulaki, S.5
Young, R.A.6
Jaenisch, R.7
-
47
-
-
84875722648
-
Utx is required for proper induction of ectoderm and mesoderm during differentiation of embryonic stem cells
-
Morales Torres, C., Laugesen, A. and Helin, K. (2013) Utx is required for proper induction of ectoderm and mesoderm during differentiation of embryonic stem cells. PLoS One, 8, e60020
-
(2013)
PLoS One
, vol.8
-
-
Morales Torres, C.1
Laugesen, A.2
Helin, K.3
-
48
-
-
84875766099
-
Retinoic acid dependent histone 3 demethylation of the clustered HOX genes during neural differentiation of human embryonic stem cells
-
Shahhoseini, M., Taghizadeh, Z., Hatami, M. and Baharvand, H. (2013) Retinoic acid dependent histone 3 demethylation of the clustered HOX genes during neural differentiation of human embryonic stem cells. Biochem. Cell Biol., 91, 116-122
-
(2013)
Biochem. Cell Biol
, vol.91
, pp. 116-122
-
-
Shahhoseini, M.1
Taghizadeh, Z.2
Hatami, M.3
Baharvand, H.4
-
49
-
-
84862777719
-
Distinct regulatory mechanisms and functions for p53-Activated and p53-repressed DNA damage response genes in embryonic stem cells
-
Li, M., He, Y., Dubois, W., Wu, X., Shi, J. and Huang, J. (2012) Distinct regulatory mechanisms and functions for p53-Activated and p53-repressed DNA damage response genes in embryonic stem cells. Mol. Cell, 46, 30-42
-
(2012)
Mol. Cell
, vol.46
, pp. 30-42
-
-
Li, M.1
He, Y.2
Dubois, W.3
Wu, X.4
Shi, J.5
Huang, J.6
-
50
-
-
0347417012
-
T-box genes in early embryogenesis
-
Showell, C., Binder, O. and Conlon, F.L. (2004) T-box genes in early embryogenesis. Dev. Dyn., 229, 201-218
-
(2004)
Dev. Dyn
, vol.229
, pp. 201-218
-
-
Showell, C.1
Binder, O.2
Conlon, F.L.3
-
51
-
-
77954758157
-
Polycomb group protein-mediated repression of transcription
-
Morey, L. and Helin, K. (2010) Polycomb group protein-mediated repression of transcription. Trends Biochem. Sci., 35, 323-332
-
(2010)
Trends Biochem. Sci
, vol.35
, pp. 323-332
-
-
Morey, L.1
Helin, K.2
-
52
-
-
57049158657
-
Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons
-
Martinez-Ceballos, E. and Gudas, L.J. (2008) Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons. J. Neurosci. Res., 86, 2809-2819
-
(2008)
J. Neurosci. Res
, vol.86
, pp. 2809-2819
-
-
Martinez-Ceballos, E.1
Gudas, L.J.2
-
53
-
-
0347623125
-
Hedgehog signaling is required for the differentiation of ES cells into neurectoderm
-
Maye, P., Becker, S., Siemen, H., Thorne, J., Byrd, N., Carpentino, J. and Grabel, L. (2004) Hedgehog signaling is required for the differentiation of ES cells into neurectoderm. Dev. Biol., 265, 276-290
-
(2004)
Dev. Biol
, vol.265
, pp. 276-290
-
-
Maye, P.1
Becker, S.2
Siemen, H.3
Thorne, J.4
Byrd, N.5
Carpentino, J.6
Grabel, L.7
-
54
-
-
80052408380
-
Directed differentiation of human embryonic stem cells to interrogate the cardiac gene regulatory network
-
Dixon, J.E., Dick, E., Rajamohan, D., Shakesheff, K.M. and Denning, C. (2011) Directed differentiation of human embryonic stem cells to interrogate the cardiac gene regulatory network. Mol. Ther., 19, 1695-1703
-
(2011)
Mol. Ther
, vol.19
, pp. 1695-1703
-
-
Dixon, J.E.1
Dick, E.2
Rajamohan, D.3
Shakesheff, K.M.4
Denning, C.5
-
55
-
-
76149087152
-
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal
-
Niakan, K.K., Ji, H., Maehr, R., Vokes, S.A., Rodolfa, K.T., Sherwood, R.I., Yamaki, M., Dimos, J.T., Chen, A.E., Melton, D.A. et al. (2010) Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. Genes Dev., 24, 312-326
-
(2010)
Genes Dev
, vol.24
, pp. 312-326
-
-
Niakan, K.K.1
Ji, H.2
Maehr, R.3
Vokes, S.A.4
Rodolfa, K.T.5
Sherwood, R.I.6
Yamaki, M.7
Dimos, J.T.8
Chen, A.E.9
Melton, D.A.10
-
56
-
-
0037111831
-
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
-
Kuzmichev, A., Nishioka, K., Erdjument-Bromage, H., Tempst, P. and Reinberg, D. (2002) Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev., 16, 2893-2905
-
(2002)
Genes Dev
, vol.16
, pp. 2893-2905
-
-
Kuzmichev, A.1
Nishioka, K.2
Erdjument-Bromage, H.3
Tempst, P.4
Reinberg, D.5
-
57
-
-
18644383738
-
Histone methyltransferase activity of a Drosophila Polycomb group repressor complex
-
Muller, J., Hart, C.M., Francis, N.J., Vargas, M.L., Sengupta, A., Wild, B., Miller, E.L., O'Connor, M.B., Kingston, R.E. and Simon, J.A. (2002) Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell, 111, 197-208
-
(2002)
Cell
, vol.111
, pp. 197-208
-
-
Muller, J.1
Hart, C.M.2
Francis, N.J.3
Vargas, M.L.4
Sengupta, A.5
Wild, B.6
Miller, E.L.7
O'Connor, M.B.8
Kingston, R.E.9
Simon, J.A.10
-
58
-
-
80455140217
-
Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
-
Sengoku, T. and Yokoyama, S. (2011) Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A. Genes Dev., 25, 2266-2277
-
(2011)
Genes Dev
, vol.25
, pp. 2266-2277
-
-
Sengoku, T.1
Yokoyama, S.2
-
59
-
-
77956634439
-
Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycombmediated repression at target genes
-
Dahle, O., Kumar, A. and Kuehn, M.R. (2010) Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycombmediated repression at target genes. Sci. Signal., 3, ra48
-
(2010)
Sci. Signal
, vol.3
-
-
Dahle, O.1
Kumar, A.2
Kuehn, M.R.3
-
60
-
-
84878661019
-
The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation
-
Kartikasari, A.E., Zhou, J.X., Kanji, M.S., Chan, D.N., Sinha, A., Grapin-Botton, A., Magnuson, M.A., Lowry, W.E. and Bhushan, A. (2013) The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation. EMBO J., 32, 1393-1408
-
(2013)
EMBO J.
, Issue.32
, pp. 1393-1408
-
-
Kartikasari, A.E.1
Zhou, J.X.2
Kanji, M.S.3
Chan, D.N.4
Sinha, A.5
Grapin-Botton, A.6
Magnuson, M.A.7
Lowry, W.E.8
Bhushan, A.9
-
61
-
-
84855957128
-
UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program
-
Lee, S., Lee, J.W. and Lee, S.K. (2012) UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program. Dev Cell, 22, 25-37
-
(2012)
Dev Cell
, vol.22
, pp. 25-37
-
-
Lee, S.1
Lee, J.W.2
Lee, S.K.3
-
62
-
-
84862622207
-
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation
-
Chen, S., Ma, J., Wu, F., Xiong, L.J., Ma, H., Xu, W., Lv, R., Li, X., Villen, J., Gygi, S.P. et al. (2012) The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation. Genes Dev., 26, 1364-1375
-
(2012)
Genes Dev
, vol.26
, pp. 1364-1375
-
-
Chen, S.1
Ma, J.2
Wu, F.3
Xiong, L.J.4
Ma, H.5
Xu, W.6
Lv, R.7
Li, X.8
Villen, J.9
Gygi, S.P.10
-
63
-
-
84865112255
-
The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming
-
Mansour, A.A., Gafni, O., Weinberger, L., Zviran, A., Ayyash, M., Rais, Y., Krupalnik, V., Zerbib, M., Amann-Zalcenstein, D., Maza, I. et al. (2012) The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming. Nature, 488, 409-413
-
(2012)
Nature
, vol.488
, pp. 409-413
-
-
Mansour, A.A.1
Gafni, O.2
Weinberger, L.3
Zviran, A.4
Ayyash, M.5
Rais, Y.6
Krupalnik, V.7
Zerbib, M.8
Amann-Zalcenstein, D.9
Maza, I.10
-
64
-
-
84874789264
-
Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination
-
Zhao, W., Li, Q., Ayers, S., Gu, Y., Shi, Z., Zhu, Q., Chen, Y., Wang, H.Y. and Wang, R.F. (2013) Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination. Cell, 152, 1037-1050
-
(2013)
Cell
, vol.152
, pp. 1037-1050
-
-
Zhao, W.1
Li, Q.2
Ayers, S.3
Gu, Y.4
Shi, Z.5
Zhu, Q.6
Chen, Y.7
Wang, H.Y.8
Wang, R.F.9
-
65
-
-
78649711427
-
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes
-
Levine, A.J. and Puzio-Kuter, A.M. (2010) The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes. Science, 330, 1340-1344
-
(2010)
Science
, vol.330
, pp. 1340-1344
-
-
Levine, A.J.1
Puzio-Kuter, A.M.2
-
67
-
-
77953062527
-
Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding
-
Schmidt, D., Wilson, M.D., Ballester, B., Schwalie, P.C., Brown, G.D., Marshall, A., Kutter, C., Watt, S., Martinez- Jimenez, C.P., Mackay, S. et al. (2010) Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding. Science, 328, 1036-1040
-
(2010)
Science
, vol.328
, pp. 1036-1040
-
-
Schmidt, D.1
Wilson, M.D.2
Ballester, B.3
Schwalie, P.C.4
Brown, G.D.5
Marshall, A.6
Kutter, C.7
Watt, S.8
Martinez-Jimenez, C.P.9
Mackay, S.10
-
68
-
-
33645381936
-
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
-
Loh, Y.H., Wu, Q., Chew, J.L., Vega, V.B., Zhang, W., Chen, X., Bourque, G., George, J., Leong, B., Liu, J. et al. (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat. Genet., 38, 431-440
-
(2006)
Nat. Genet
, vol.38
, pp. 431-440
-
-
Loh, Y.H.1
Wu, Q.2
Chew, J.L.3
Vega, V.B.4
Zhang, W.5
Chen, X.6
Bourque, G.7
George, J.8
Leong, B.9
Liu, J.10
-
69
-
-
73049105546
-
Modeling disease in human ESCs using an efficient BAC-based homologous recombination system
-
Song, H., Chung, S.K. and Xu, Y. (2010) Modeling disease in human ESCs using an efficient BAC-based homologous recombination system. Cell Stem Cell, 6, 80-89
-
(2010)
Cell Stem Cell
, vol.6
, pp. 80-89
-
-
Song, H.1
Chung, S.K.2
Xu, Y.3
-
70
-
-
78650873252
-
P63 and p73, the ancestors of p53
-
Dotsch, V., Bernassola, F., Coutandin, D., Candi, E. and Melino, G. (2010) p63 and p73, the ancestors of p53. Cold Spring Harb. Perspect. Biol., 2, a004887
-
(2010)
Cold Spring Harb. Perspect. Biol
, vol.2
-
-
Dotsch, V.1
Bernassola, F.2
Coutandin, D.3
Candi, E.4
Melino, G.5
-
71
-
-
0029347164
-
High-frequency developmental abnormalities in p53-deficient mice
-
Armstrong, J.F., Kaufman, M.H., Harrison, D.J. and Clarke, A.R. (1995) High-frequency developmental abnormalities in p53-deficient mice. Curr. Biol., 5, 931-936
-
(1995)
Curr. Biol
, vol.5
, pp. 931-936
-
-
Armstrong, J.F.1
Kaufman, M.H.2
Harrison, D.J.3
Clarke, A.R.4
-
72
-
-
36749081541
-
P53 regulates maternal reproduction through LIF
-
Hu, W., Feng, Z., Teresky, A.K. and Levine, A.J. (2007) p53 regulates maternal reproduction through LIF. Nature, 450, 721-724
-
(2007)
Nature
, vol.450
, pp. 721-724
-
-
Hu, W.1
Feng, Z.2
Teresky, A.K.3
Levine, A.J.4
-
73
-
-
30344478870
-
A global map of p53 transcription-factor binding sites in the human genome
-
Wei, C.L., Wu, Q., Vega, V.B., Chiu, K.P., Ng, P., Zhang, T., Shahab, A., Yong, H.C., Fu, Y., Weng, Z. et al. (2006) A global map of p53 transcription-factor binding sites in the human genome. Cell, 124, 207-219
-
(2006)
Cell
, vol.124
, pp. 207-219
-
-
Wei, C.L.1
Wu, Q.2
Vega, V.B.3
Chiu, K.P.4
Ng, P.5
Zhang, T.6
Shahab, A.7
Yong, H.C.8
Fu, Y.9
Weng, Z.10
-
74
-
-
84055190692
-
Distinct p53 genomic binding patterns in normal and cancer-derived human cells
-
Botcheva, K., McCorkle, S.R., McCombie, W.R., Dunn, J.J. and Anderson, C.W. (2011) Distinct p53 genomic binding patterns in normal and cancer-derived human cells. Cell Cycle, 10, 4237-4249
-
(2011)
Cell Cycle
, vol.10
, pp. 4237-4249
-
-
Botcheva, K.1
McCorkle, S.R.2
McCombie, W.R.3
Dunn, J.J.4
Anderson, C.W.5
-
75
-
-
33644750115
-
Mirbase: MicroRNA sequences, targets and gene nomenclature
-
Griffiths-Jones, S., Grocock, R.J., van Dongen, S., Bateman, A. and Enright, A.J. (2006) miRBase: MicroRNA sequences, targets and gene nomenclature. Nucleic Acids Res., 34, D140-D144
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
Van Dongen, S.3
Bateman, A.4
Enright, A.J.5
|