Dysregulation of cellular iron metabolism in Friedreich ataxia: From primary iron-sulfur cluster deficit to mitochondrial iron accumulation

Frontiers in Pharmacology

Volumn 5 JUN, Issue , 2014, Pages

  Martelli, Alain ^a,b,c,d,e   Puccio, Hélène ^a,b,c,d,e  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e Chaire de Génétique Humaine   (France)

Author keywords

Frataxin; Friedreich ataxia; Iron metabolism; Iron metabolism disorders; Iron sulfur cluster; Mitochondria

Indexed keywords

DEFERIPRONE; FRATAXIN; IRON; IRON BINDING PROTEIN; SULFUR;

BIOCHEMISTRY; BIOGENESIS; CARDIOMYOPATHY; CELL METABOLISM; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; FRIEDREICH ATAXIA; FXN GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC DISORDER; HISTOPATHOLOGY; HUMAN; IRON CHELATION; IRON METABOLISM; IRON OVERLOAD; MAMMAL; METABOLIC DISORDER; METABOLIC REGULATION; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN MODIFICATION; REVIEW;

EID: 84904734583     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00130     Document Type: Review

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