Dynamics, stability and iron-binding activity of frataxin clinical mutants

FEBS Journal

Volumn 275, Issue 14, 2008, Pages 3680-3690

  Correia, Ana R ^a   Pastore, Chiara ^b   Adinolfi, Salvatore ^b   Pastore, Annalisa ^b   Gomes, Cláudio M ^a  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Clinical mutants; Frataxin; Friedreich's ataxia; Protein dynamics and flexibility; Protein folding

Indexed keywords

FRATAXIN; MUTANT PROTEIN; IRON; IRON BINDING PROTEIN; TRYPSIN;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; FRIEDREICH ATAXIA; HUMAN; IRON BINDING CAPACITY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN STABILITY; THERMODYNAMICS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; KINETICS; METABOLISM; POINT MUTATION;

FRIEDREICH ATAXIA; HUMANS; IRON; IRON-BINDING PROTEINS; KINETICS; MODELS, MOLECULAR; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; THERMODYNAMICS; TRYPSIN;

EID: 50549100932     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06512.x     Document Type: Article

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