Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex

Biochemistry

Volumn 49, Issue 43, 2010, Pages 9132-9139

  Tsai, Chi Lin ^a   Barondeau, David P ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC ACTIVATOR; CARDIO-VASCULAR DISEASE; CATALYTIC EFFICIENCIES; CLUSTER ASSEMBLY; COMPLEX FORMATIONS; CYSTEINE DESULFURASE; FERROUS IRON; FRATAXIN; FRIEDREICH'S ATAXIAS; HUMAN PROTEINS; IN-VITRO; MITOCHONDRIAL DYSFUNCTION; NEURODEGENERATIVE; NEURODEGENERATIVE DISEASE; OXIDATIVE STRESS RESPONSE; OXIDIZING CONDITIONS;

AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; CHEMICAL ACTIVATION; IRON; MACHINERY; SULFUR;

IRON COMPOUNDS;

BACTERIAL PROTEIN; CYSTATHIONINE GAMMA LYASE; CYSTEINE; FERROUS ION; FRATAXIN; IRON SULFUR PROTEIN; LYASE; PROTEIN ISD11; PROTEIN ISU2; PROTEIN NFS1; SULFUR; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS;

ALLOSTERIC REGULATION; BIOLOGICAL TRANSPORT; CARBON-SULFUR LYASES; HUMANS; IRON; IRON-BINDING PROTEINS; IRON-REGULATORY PROTEINS; IRON-SULFUR PROTEINS; MITOCHONDRIAL PROTEINS; MULTIPROTEIN COMPLEXES; SULFUR;

EID: 78049305276     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1013062     Document Type: Article

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