Drug-induced nephrotoxicity: Clinical impact and preclinical in vitro models

Molecular Pharmaceutics

Volumn 11, Issue 7, 2014, Pages 1933-1948

  Tiong, Ho Yee ^a   Huang, Peng ^b   Xiong, Sijing ^b   Li, Yao ^b   Vathsala, Anantharaman ^a   Zink, Daniele ^b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

Author keywords

drug induced nephrotoxicity; in vitro model; nephrotoxicant; predictivity; renal proximal tubular cell; stem cell

Indexed keywords

ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; IMMUNOSUPPRESSIVE AGENT; TELOMERASE REVERSE TRANSCRIPTASE;

ACUTE KIDNEY FAILURE; CELL IMMORTALIZATION; DIAGNOSTIC IMAGING; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL; KIDNEY TRANSPLANTATION; KIDNEY TUBULE CELL; NEPHROTOXICITY; NONHUMAN; PLURIPOTENT STEM CELL; PREDICTION; PRIORITY JOURNAL; REVIEW; STEM CELL; STRESS; ANIMAL; CHEMICALLY INDUCED; DRUG APPROVAL; DRUG EFFECTS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; KIDNEY; PRECLINICAL STUDY; PROCEDURES;

ACUTE KIDNEY INJURY; ANIMALS; DRUG APPROVAL; DRUG EVALUATION, PRECLINICAL; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; HUMANS; IN VITRO TECHNIQUES; KIDNEY;

EID: 84903973480     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400720w     Document Type: Review

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