Generation of easily accessible human kidney tubules on two-dimensional surfaces in vitro

Journal of Cellular and Molecular Medicine

Volumn 15, Issue 6, 2011, Pages 1287-1298

  Zhang, Huishi ^a   Lau, Samantha Fong Ting ^a   Heng, Ber Fong ^a   Teo, Pei Yun ^a   Alahakoon, P K D Thilini ^a   Ni, Ming ^a   Tasnim, Farah ^a   Ying, Jackie Y ^a   Zink, Daniele ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

Author keywords

Kidney tissue engineering; Primary human renal proximal tubule cells; Renal tubules; Tissue like structures

Indexed keywords

ACTA2 PROTEIN, HUMAN; ACTIN; COLLAGEN; LAMININ; MATRIGEL; PROTEOGLYCAN; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; BIOSYNTHESIS; CELL COMMUNICATION; CELL CULTURE; CELL MOTION; CULTURE TECHNIQUE; CYTOLOGY; DRUG COMBINATION; DRUG EFFECT; EPITHELIUM CELL; HUMAN; ION TRANSPORT; KIDNEY PROXIMAL TUBULE; MESENCHYMAL STEM CELL; METHODOLOGY; MYOFIBROBLAST; REGENERATION; TISSUE ENGINEERING;

ACTINS; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; CELL MOVEMENT; CELLS, CULTURED; COLLAGEN; DRUG COMBINATIONS; EPITHELIAL CELLS; HUMANS; ION TRANSPORT; KIDNEY TUBULES, PROXIMAL; LAMININ; MESENCHYMAL STEM CELLS; MYOFIBROBLASTS; PROTEOGLYCANS; REGENERATION; TISSUE ENGINEERING; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77958558146     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01113.x     Document Type: Article

References (47)

1. Dressler G. Tubulogenesis in the developing mammalian kidney. Trends Cell Biol. 2002; 12: 390-5.
2. Vainio S, Lin Y. Coordinating early kidney development: lessons from gene targeting. Nat Rev Genet. 2002; 3: 533-43.
3. Han HJ, Sigurdson WJ, Nickerson PA, et al Both mitogen activated protein kinase and the mammalian target of rapamycin modulate the development of functional renal proximal tubules in matrigel. J Cell Sci. 2004; 117: 1821-33.
4. Humes HD, Krauss JC, Cieslinski DA, et al Tubulogenesis from isolated single cells of adult mammalian kidney: clonal analysis with a recombinant retrovirus. Am J Physiol. 1996; 271: F42-9.
5. Karihaloo A, Nickel C, Cantley LG. Signals which build a tubule. Nephron Exp Nephrol. 2005; 100: e40-5.
6. Lubarsky B, Krasnow MA. Tube morphogenesis: making and shaping biological tubes. Cell. 2003; 112: 19-28.
7. Montesano R, Matsumoto K, Nakamura T, et al Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell. 1991; 67: 901-8.
8. Montesano R, Schaller G, Orci L. Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell. 1991; 66: 697-711.
9. Nickel C, Benzing T, Sellin L, et al The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells. J Clin Invest. 2002; 109: 481-9.
10. Sakurai H, Barros EJ, Tsukamoto T, et al An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors. Proc Natl Acad Sci USA. 1997; 94: 6279-84.
11. Taub M, Wang Y, Szczesny TM, et al Epidermal growth factor or transforming growth factor alpha is required for kidney tubulogenesis in matrigel cultures in serum-free medium. Proc Natl Acad Sci USA. 1990; 87: 4002-6.
12. Zegers MM, O'Brien LE, Yu W, et al Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol. 2003; 13: 169-76.
13. Chen N, Aleksa K, Woodland C, et al The effect of N-acetylcysteine on ifosfamide-induced nephrotoxicity: in vitro studies in renal tubular cells. Transl Res. 2007; 150: 51-7.
14. Copeland JW, Beaumont BW, Merrilees MJ, et al Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: effects of rapamycin, mycophenolate, cyclosporin, azathioprine, and methylprednisolone. Transplantation. 2007; 83: 809-14.
15. Li W, Lam M, Choy D, et al Human primary renal cells as a model for toxicity assessment of chemo-therapeutic drugs. Toxicol In Vitro. 2006; 20: 669-76.
16. Luhe A, Kunkele KP, Haiker M, et al Preclinical evidence for nitrogen-containing bisphosphonate inhibition of farnesyl diphosphate (FPP) synthase in the kidney: implications for renal safety. Toxicol In Vitro. 2008; 22: 899-909.
17. McMorrow T, Gaffney MM, Slattery C, et al Cyclosporine A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells. Nephrol Dial Transplant. 2005; 20: 2215-25.
18. Pallet N, Rabant M, Xu-Dubois YC, et al Response of human renal tubular cells to cyclosporine and sirolimus: a toxicogenomic study. Toxicol Appl Pharmacol. 2008; 229: 184-96.
19. Pfaller W, Gstraunthaler G. Nephrotoxicity testing in vitro-what we know and what we need to know. Environ Health Perspect. 1998; 106: 559-69.
20. Rached E, Hoffmann D, Blumbach K, et al Evaluation of putative biomarkers of nephrotoxicity after exposure to ochratoxin A in vivo and in vitro. Toxicol Sci. 2008; 103: 371-81.
21. Fissell WH, Dyke DB, Weitzel WF, et al Bioartificial kidney alters cytokine response and hemodynamics in endotoxin-challenged uremic animals. Blood Purif. 2002; 20: 55-60.
22. Huijuan M, Xiaoyun W, Xumin Y, et al Effect of continuous bioartificial kidney therapy on porcine multiple organ dysfunction syndrome with acute renal failure. Asaio J. 2007; 53: 329-34.
23. Humes HD, Buffington DA, MacKay SM, et al Replacement of renal function in uremic animals with a tissue-engineered kidney. Nat Biotechnol. 1999; 17: 451-5.
24. Humes HD, Fissell WH, Weitzel WF, et al Metabolic replacement of kidney function in uremic animals with a bioartificial kidney containing human cells. Am J Kidney Dis. 2002; 39: 1078-87.
25. Humes HD, Weitzel WF, Bartlett RH, et al Initial clinical results of the bioartificial kidney containing human cells in ICU patients with acute renal failure. Kidney Int. 2004; 66: 1578-88.
26. Inagaki M, Yokoyama TA, Sawada K, et al Prevention of LLC-PK(1) cell overgrowth in a bioartificial renal tubule device using a MEK inhibitor, U0126. J Biotechnol. 2007; 132: 57-64.
27. MacKay SM, Funke AJ, Buffington DA, et al Tissue engineering of a bioartificial renal tubule. Asaio J. 1998; 44: 179-83.
28. Saito A, Aung T, Sekiguchi K, et al Present status and perspectives of bioartificial kidneys. J Artif Organs. 2006; 9: 130-5.
29. Tumlin J, Wali R, Williams W, et al Efficacy and safety of renal tubule cell therapy for acute renal failure. J Am Soc Nephrol. 2008; 19: 1034-40.
30. Zhang H, Tasnim F, Ying JY, et al The impact of extracellular matrix coatings on the performance of human renal cells applied in bioartificial kidneys. Biomaterials. 2009; 30: 2899-911.
31. Masereeuw R, Moons MM, Toomey BH, et al Active lucifer yellow secretion in renal proximal tubule: evidence for organic anion transport system crossover. J Pharmacol Exp Ther. 1999; 289: 1104-11.
32. Miller DS, Letcher S, Barnes DM. Fluorescence imaging study of organic anion transport from renal proximal tubule cell to lumen. Am J Physiol. 1996; 271: F508-20.
33. Altenberg GA, Vanoye CG, Han ES, et al Relationships between rhodamine 123 transport, cell volume, and ion-channel function of P-glycoprotein. J Biol Chem. 1994; 269: 7145-9.
34. Lelong IH, Guzikowski AP, Haugland RP, et al Fluorescent verapamil derivative for monitoring activity of the multidrug transporter. Mol Pharmacol. 1991; 40: 490-4.
35. Cottingham MG, Bain CD, Vaux DJ. Rapid method for measurement of surface tension in multiwell plates. Lab Invest. 2004; 84: 523-9.
36. Kelynack KJ, Hewitson TD, Nicholls KM, et al Human renal fibroblast contraction of collagen I lattices is an integrin-mediated process. Nephrol Dial Transplant. 2000; 15: 1766-72.
37. Fan JM, Ng YY, Hill PA, et al Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro. Kidney Int. 1999; 56: 1455-67.
38. Humes HD, Cieslinski DA. Interaction between growth factors and retinoic acid in the induction of kidney tubulogenesis in tissue culture. Exp Cell Res. 1992; 201: 8-15.
39. Bard JB, Gordon A, Sharp L, et al Early nephron formation in the developing mouse kidney. J Anat. 2001; 199: 385-92.
40. Powell DW, Mifflin RC, Valentich JD, et al Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol. 1999; 277: C1-9.
41. Badid C, Mounier N, Costa AM, et al Role of myofibroblasts during normal tissue repair and excessive scarring: interest of their assessment in nephropathies. Histol Histopathol. 2000; 15: 269-80.
42. Ishibe S, Cantley LG. Epithelial-mesenchymal-epithelial cycling in kidney repair. Curr Opin Nephrol Hypertens. 2008; 17: 379-85.
43. Qi W, Chen X, Poronnik P, et al The renal cortical fibroblast in renal tubulointerstitial fibrosis. Int J Biochem Cell Biol. 2006; 38: 1-5.
44. Simic P, Vukicevic S. Bone morphogenetic proteins in development and homeostasis of kidney. Cytokine Growth Factor Rev. 2005; 16: 299-308.
45. Yang J, Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol. 2001; 159: 1465-75.
46. Zeisberg M, Hanai J, Sugimoto H, et al BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med. 2003; 9: 964-8.
47. Wang S, Hirschberg R. BMP7 antagonizes TGF-beta-dependent fibrogenesis in mesangial cells. Am J Physiol Renal Physiol. 2003; 284: F1006-13.