Urinary and serum biomarkers for the diagnosis of acute kidney injury: An in-depth review of the literature

Nephrology Dialysis Transplantation

Volumn 28, Issue 2, 2013, Pages 254-273

  Vanmassenhove, Jill ^a   Vanholder, Raymond ^a   Nagler, Evi ^a   Van Biesen, Wim ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

acute kidney injury; biomarkers; dialysis; renal failure; urinary

Indexed keywords

11 KETO THROMBOXANE B2; ACETYLGLUCOSAMINIDASE; ALKALINE PHOSPHATASE; ALPHA 1 MICROGLOBULIN; BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; CYSTATIN C; FATTY ACID BINDING PROTEIN; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE ALPHA; GLUTATHIONE TRANSFERASE P1; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 8; KIDNEY INJURY MOLECULE 1; LIVER FATTY ACID BINDING PROTEIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; OROSOMUCOID; PLASMINOGEN ACTIVATOR INHIBITOR 1; PODOCALYXIN; RETINOL BINDING PROTEIN; SCATTER FACTOR; THROMBOXANE B2 DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ACUTE KIDNEY FAILURE; BLOOD ANALYSIS; CLINICAL PRACTICE; CONTRAST INDUCED NEPHROPATHY; CRITICALLY ILL PATIENT; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; EMERGENCY WARD; HEART SURGERY; HUMAN; MEDLINE; PEDIATRICS; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTEIN URINE LEVEL; RECEIVER OPERATING CHARACTERISTIC; RENAL REPLACEMENT THERAPY; REVIEW; SYSTEMATIC REVIEW; URINALYSIS;

ACUTE KIDNEY INJURY; ACUTE-PHASE PROTEINS; BIOLOGICAL MARKERS; DIAGNOSIS, DIFFERENTIAL; HUMANS; LIPOCALINS; MEMBRANE GLYCOPROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTORS, VIRUS; REPRODUCIBILITY OF RESULTS;

EID: 84874529776     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs380     Document Type: Review

References (108)

1. Brivet FG, Kleinknecht DJ, Loirat P et al. Acute renal failure in intensive care units-causes, outcome, and prognostic factors of hospital mortality; a prospective, multicenter study. French Study Group on Acute Renal Failure. Crit Care Med 1996; 24: 192-198 (Pubitemid 26065324)
2. Chertow GM, Burdick E, Honour M et al. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 2005; 16: 3365-3370 (Pubitemid 46179340)
3. Lameire N, Van BW, Vanholder R. Acute renal failure. Lancet 2005; 365: 417-430 (Pubitemid 40179230)
4. Coca SG, Yalavarthy R, Concato J et al. Biomarkers for the diagnosis and risk stratification of acute kidney injury: a systematic review. Kidney Int 2008; 73: 1008-1016 (Pubitemid 351543898)
5. Lameire NH, Vanholder RC, Van Biesen WA. How to use biomarkers efficiently in acute kidney injury. Kidney Int 2011; 79: 1047-1050
6. Bennett M, Dent CL, Ma Q et al. Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study. Clin J Am Soc Nephrol 2008; 3: 665-673
7. Dennen P, Altmann C, Kaufman J et al. Urine interleukin-6 is an early biomarker of acute kidney injury in children undergoing cardiac surgery. Crit Care 2010; 14: R181
8. Dent CL, Ma Q, Dastrala S et al. Plasma neutrophil gelatinaseassociated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. Crit Care 2007; 11: R127
9. Krawczeski CD, Vandevoorde RG, Kathman Tet al. Serum cystatin C is an early predictive biomarker of acute kidney injury after pediatric cardiopulmonary bypass. Clin J Am Soc Nephrol 2010; 5: 1552-1557
10. Krawczeski CD, Woo JG, Wang Y et al. Neutrophil gelatinaseassociated lipocalin concentrations predict development of acute kidney injury in neonates and children after cardiopulmonary bypass. J Pediatr 2011; 158: 1009-1015
11. Liu KD, Altmann C, Smits G et al. Serum interleukin-6 and interleukin-8 are early biomarkers of acute kidney injury and predict prolonged mechanical ventilation in children undergoing cardiac surgery: a case-control study. Crit Care 2009; 13: R104
12. Mishra J, Dent C, Tarabishi R et al. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 2005; 365: 1231-1238 (Pubitemid 40469655)
13. Parikh CR, Devarajan P, Zappitelli M et al. Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery. J Am Soc Nephrol 2011; 22: 1737-1747
14. Portilla D, Dent C, Sugaya T et al. Liver fatty acid-binding protein as a biomarker of acute kidney injury after cardiac surgery. Kidney Int 2008; 73: 465-472 (Pubitemid 351186293)
15. Zappitelli M, Krawczeski CD, Devarajan P et al. Early postoperative serum cystatin C predicts severe acute kidney injury following pediatric cardiac surgery. Kidney Int 2011; 80: 655-662
16. Parikh CR, Mishra J, Thiessen-Philbrook H et al. Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery. Kidney Int 2006; 70: 199-203 (Pubitemid 44000139)
17. Hirsch R, Dent C, Pfriem H et al. NGAL is an early predictive biomarker of contrast-induced nephropathy in children. Pediatr Nephrol 2007; 22: 2089-2095 (Pubitemid 350090716)
18. Du Y, Zappitelli M, Mian A et al. Urinary biomarkers to detect acute kidney injury in the pediatric emergency center. Pediatr Nephrol 2011; 26: 267-274
19. Haase-Fielitz A, Bellomo R, Devarajan P et al. The predictive performance of plasma neutrophil gelatinase-associated lipocalin (NGAL) increases with grade of acute kidney injury. Nephrol Dial Transplant 2009; 24: 3349-3354
20. Koyner JL, Bennett MR, Worcester EM et al. Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery. Kidney Int 2008; 74: 1059-1069
21. Nickolas TL, O'Rourke MJ, Yang J et al. Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury. Ann Intern Med 2008; 148: 810-819 (Pubitemid 351786928)
22. Nickolas TL, Schmidt-Ott KM, Canetta P et al. Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage: a multicenter prospective cohort study. J Am Coll Cardiol 2012; 59: 246-255
23. Shapiro NI, Trzeciak S, Hollander JE et al. The diagnostic accuracy of plasma neutrophil gelatinase-associated lipocalin in the prediction of acute kidney injury in emergency department patients with suspected sepsis. Ann Emerg Med 2010; 56: 52-59
24. Soto K, Coelho S, Rodrigues B et al. Cystatin C as a marker of acute kidney injury in the emergency department. Clin J Am Soc Nephrol 2010; 5: 1745-1754
25. Bolignano D, Lacquaniti A, Coppolino G et al. Neutrophil gelatinase-associated lipocalin as an early biomarker of nephropathy in diabetic patients. Kidney Blood Press Res 2009; 32: 91-98
26. Brunner HI, Mueller M, Rutherford C et al. Urinary neutrophil gelatinase-associated lipocalin as a biomarker of nephritis in childhood-onset systemic lupus erythematosus. Arthritis Rheum 2006; 54: 2577-2584 (Pubitemid 44205019)
27. Parravicini E, Nemerofsky SL, Michelson KA et al. Urinary neutrophil gelatinase-associated lipocalin is a promising biomarker for late onset culture-positive sepsis in very low birth weight infants. Pediatr Res 2010; 67: 636-640
28. Trachtman H, Christen E, Cnaan A et al. Urinary neutrophil gelatinase-associated lipocalcin in D+HUS: a novel marker of renal injury. Pediatr Nephrol 2006; 21: 989-994 (Pubitemid 43885099)
29. Bolignano D, Lacquaniti A, Coppolino G et al. Neutrophil gelatinase-associated lipocalin reflects the severity of renal impairment in subjects affected by chronic kidney disease. Kidney Blood Press Res 2008; 31: 255-258
30. Mitsnefes MM, Kathman TS, Mishra J et al. Serum neutrophil gelatinase-associated lipocalin as a marker of renal function in children with chronic kidney disease. Pediatr Nephrol 2007; 22: 101-108 (Pubitemid 46138368)
31. Haase M, Devarajan P, Haase-Fielitz A et al. The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies. J Am Coll Cardiol 2011; 57: 1752-1761
32. Constantin JM, Futier E, Perbet S et al. Plasma neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in adult critically ill patients: a prospective study. J Crit Care 2010; 25: 176
33. Cruz DN, de Cal M, Garzotto F et al. Plasma neutrophil gelatinase-associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population. Intensive Care Med 2010; 36: 444-451
34. Bachorzewska-Gajewska H, Malyszko J, Sitniewska E et al. Neutrophil-gelatinase-associated lipocalin and renal function after percutaneous coronary interventions. Am J Nephrol 2006; 26: 287-292 (Pubitemid 44121091)
35. Bachorzewska-Gajewska H, Poniatowski B, Dobrzycki S. NGAL (neutrophil gelatinase-associated lipocalin) and L-FABP after percutaneous coronary interventions due to unstable angina in patients with normal serum creatinine. Adv Med Sci 2009; 54: 221-224
36. Nejat M, Pickering J, Devarajan P et al. Some biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney Int 2012; 81: 1254-1262.
37. Bucaloiu I, Kirchner HL, Norfolk ER et al. Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury. Kidney Int 2012; 81: 477-485
38. Coca S, Singanamala S, Parikh CR. Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis. Kidney Int 2012; 81: 442-448
39. Liangos O, Perianayagam MC, Vaidya VS et al. Urinary N-acetylbeta-( D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure. J Am Soc Nephrol 2007; 18: 904-912 (Pubitemid 46434507)
40. Singer E, Elger A, Elitok S et al. Urinary neutrophil gelatinaseassociated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes. Kidney Int 2011; 80: 405-414
41. Washburn KK, Zappitelli M, Arikan AA et al. Urinary interleukin-18 is an acute kidney injury biomarker in critically ill children. Nephrol Dial Transplant 2008; 23: 566-572 (Pubitemid 351767629)
42. Wheeler DS, Devarajan P, Ma Q et al. Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock. Crit Care Med 2008; 36: 1297-1303 (Pubitemid 351482681)
43. Zappitelli M, Washburn KK, Arikan AA et al. Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study. Crit Care 2007; 11: R84
44. Han WK, Wagener G, Zhu Y et al. Urinary biomarkers in the early detection of acute kidney injury after cardiac surgery. Clin J Am Soc Nephrol 2009; 4: 873-882
45. Koyner JL, Vaidya VS, Bennett MR et al. Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol 2010; 5: 2154-2165
46. Wagener G, Gubitosa G, Wang S et al. Urinary neutrophil gelatinase-associated lipocalin and acute kidney injury after cardiac surgery. Am J Kidney Dis 2008; 52: 425-433
47. Liangos O, Tighiouart H, Perianayagam MC et al. Comparative analysis of urinary biomarkers for early detection of acute kidney injury following cardiopulmonary bypass. Biomarkers 2009; 14: 423-431
48. Haase M, Bellomo R, Story D et al. Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: a prospective observational cohort study. Crit Care 2008; 12: R96
49. Perry TE, Muehlschlegel JD, Liu KY et al. Plasma neutrophil gelatinase-associated lipocalin and acute postoperative kidney injury in adult cardiac surgical patients. Anesth Analg 2010; 110: 1541-1547
50. Haase-Fielitz A, Bellomo R, Devarajan P et al. Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery-a prospective cohort study. Crit Care Med 2009; 37: 553-560
51. McIlroy DR, Wagener G, Lee HT. Neutrophil gelatinase-associated lipocalin and acute kidney injury after cardiac surgery: the effect of baseline renal function on diagnostic performance. Clin J Am Soc Nephrol 2010; 5: 211-219
52. Devarajan P. Update on mechanisms of ischemic acute kidney injury. J Am Soc Nephrol 2006; 17: 1503-1520 (Pubitemid 43841396)
53. Nakamura T, Sugaya T, Koide H. Urinary liver-type fatty acidbinding protein in septic shock: effect of polymyxin B-immobilized fiber hemoperfusion. Shock 2009; 31: 454-459
54. Chawla LS, Seneff MG, Nelson DR et al. Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis. Clin J Am Soc Nephrol 2007; 2: 22-30
55. Bagshaw SM, Bennett M, Haase M et al. Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus non-septic acute kidney injury in critical illness. Intensive Care Med 2010; 36: 452-461
56. Siew ED, Ware LB, Gebretsadik T et al. Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J Am Soc Nephrol 2009; 20: 1823-1832
57. de Geus HR, Bakker J, Lesaffre EM et al. Neutrophil gelatinaseassociated lipocalin at ICU admission predicts for acute kidney injury in adult patients. Am J Respir Crit Care Med 2011; 183: 907-914
58. Perianayagam MC, Seabra VF, Tighiouart H et al. Serum cystatin C for prediction of dialysis requirement or death in acute kidney injury: a comparative study. Am J Kidney Dis 2009; 54: 1025-1033
59. Nejat M, Pickering JW, Walker RJ et al. Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit. Crit Care 2010; 14: R85
60. Siew ED, Ikizler TA, Gebretsadik T et al. Elevated urinary IL-18 levels at the time of ICU admission predict adverse clinical outcomes. Clin J Am Soc Nephrol 2010; 5: 1497-1505
61. Ferguson MA, Vaidya VS, Waikar SS et al. Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. Kidney Int 2010; 77: 708-714
62. Endre ZH, Pickering JW, Walker RJ et al. Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney Int 2011; 79: 1119-1130
63. Metzger J, Kirsch T, Schiffer E et al. Urinary excretion of twenty peptides forms an early and accurate diagnostic pattern of acute kidney injury. Kidney Int 2010; 78: 1252-1262
64. Ling W, Zhaohui N, Ben H et al. Urinary IL-18 and NGAL as early predictive biomarkers in contrast-induced nephropathy after coronary angiography. Nephron Clin Pract 2008; 108: c176-c181 (Pubitemid 351588109)
65. Bulent Gul CB, Gullulu M, Oral B et al. Urinary IL-18: a marker of contrast-induced nephropathy following percutaneous coronary intervention? Clin Biochem 2008; 41: 544-547
66. Hemdahl AL, Gabrielsen A, Zhu C et al. Expression of neutrophil gelatinase-associated lipocalin in atherosclerosis and myocardial infarction. Arterioscler Thromb Vasc Biol 2006; 26: 136-142 (Pubitemid 43732240)
67. Parikh CR, Coca SG, Thiessen-Philbrook H et al. Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery. J Am Soc Nephrol 2011; 22: 1748-1757
68. Xin C, Yulong X, Yu C et al. Urine neutrophil gelatinase-associated lipocalin and interleukin-18 predict acute kidney injury after cardiac surgery. Ren Fail 2008; 30: 904-913
69. Wagener G, Jan M, Kim M et al. Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery. Anesthesiology 2006; 105: 485-491 (Pubitemid 44310430)
70. Tuladhar SM, Puntmann VO, Soni M et al. Rapid detection of acute kidney injury by plasma and urinary neutrophil gelatinaseassociated lipocalin after cardiopulmonary bypass. J Cardiovasc Pharmacol 2009; 53: 261-266
71. Prabhu A, Sujatha DI, Ninan B et al. Neutrophil gelatinase associated lipocalin as a biomarker for acute kidney injury in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass. Ann Vasc Surg 2010; 24: 525-531
72. Haase M, Bellomo R, Devarajan P et al. Novel biomarkers early predict the severity of acute kidney injury after cardiac surgery in adults. Ann Thorac Surg 2009; 88: 124-130
73. Koyner JL, Garg AX, Coca SG et al. Biomarkers predict progression of acute kidney injury after cardiac surgery. J Am Soc Nephrol 2012; 23: 905-914
74. Heise D, Rentsch K, Braeuer A et al. Comparison of urinary neutrophil glucosaminidase-associated lipocalin, cystatin C, and alpha1-microglobulin for early detection of acute renal injury after cardiac surgery. Eur J Cardiothorac Surg 2011; 39: 38-43
75. Ristikankare A, Poyhia R, Kuitunen A et al. Serum cystatin C in elderly cardiac surgery patients. Ann Thorac Surg 2010; 89: 689-694
76. Wald R, Liangos O, Perianayagam MC et al. Plasma cystatin C and acute kidney injury after cardiopulmonary bypass. Clin J Am Soc Nephrol 2010; 5: 1373-1379
77. Liang XL, Liu SX, Chen YH et al. Combination of urinary kidney injury molecule-1 and interleukin-18 as early biomarker for the diagnosis and progressive assessment of acute kidney injury following cardiopulmonary bypass surgery: a prospective nested case-control study. Biomarkers 2010; 15: 332-339
78. Jorres A, Kordonouri O, Schiessler A et al. Urinary excretion of thromboxane and markers for renal injury in patients undergoing cardiopulmonary bypass. Artif Organs 1994; 18: 565-569 (Pubitemid 24281042)
79. da Silva Magro MC, de Fatima Fernandes Vattimo M. Does urinalysis predict acute renal failure after heart surgery? Ren Fail 2004; 26: 385-392 (Pubitemid 39167615)
80. Eijkenboom JJ, van Eijk LT, Pickkers P et al. Small increases in the urinary excretion of glutathione S-transferase A1 and P1 after cardiac surgery are not associated with clinically relevant renal injury. Intensive Care Med 2005; 31: 664-667 (Pubitemid 40684984)
81. Liangos O, Kolyada A, Tighiouart H et al. Interleukin-8 and acute kidney injury following cardiopulmonary bypass: a prospective cohort study. Nephron Clin Pract 2009; 113: c148-c154
82. Gueret G, Lion F, Guriec N et al. Acute renal dysfunction after cardiac surgery with cardiopulmonary bypass is associated with plasmatic IL6 increase. Cytokine 2009; 45: 92-98
83. Ahlstrom A, Tallgren M, Peltonen S et al. Evolution and predictive power of serum cystatin C in acute renal failure. Clin Nephrol 2004; 62: 344-350 (Pubitemid 39480840)
84. Herget-Rosenthal S, Poppen D, Husing J et al. Prognostic value of tubular proteinuria and enzymuria in nonoliguric acute tubular necrosis. Clin Chem 2004; 50: 552-558 (Pubitemid 38297305)
85. Herget-Rosenthal S, Marggraf G, Husing J et al. Early detection of acute renal failure by serum cystatin C. Kidney Int 2004; 66: 1115-1122 (Pubitemid 39121017)
86. Mazul-Sunko B, Zarkovic N, Vrkic N et al. Proatrial natriuretic peptide (1-98), but not cystatin C, is predictive for occurrence of acute renal insufficiency in critically ill septic patients. Nephron Clin Pract 2004; 97: c103-c107 (Pubitemid 39077826)
87. Hei ZQ, Li XY, Shen N et al. Prognostic values of serum cystatin C and beta2 microglobulin, urinary beta2 microglobulin and Nacetyl-beta-D- glucosaminidase in early acute renal failure after liver transplantation. Chin Med J (Engl) 2008; 121: 1251-1256
88. Portal AJ, McPhail MJ, Bruce M et al. Neutrophil gelatinaseassociated lipocalin predicts acute kidney injury in patients undergoing liver transplantation. Liver Transpl 2010; 16: 1257-1266
89. Nejat M, Pickering JW, Walker RJ et al. Rapid detection of acute kidney injury by plasma cystatin C in the intensive care unit. Nephrol Dial Transplant 2010; 25: 3283-3289
90. Royakkers AA, Korevaar JC, van Suijlen JD et al. Serum and urine cystatin C are poor biomarkers for acute kidney injury and renal replacement therapy. Intensive Care Med 2011; 37: 493-501
91. Niemann CU, Walia A, Waldman J et al. Acute kidney injury during liver transplantation as determined by neutrophil gelatinaseassociated lipocalin. Liver Transpl 2009; 15: 1852-1860
92. Makris K, Markou N, Evodia E et al. Urinary neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in critically ill multiple trauma patients. Clin Chem Lab Med 2009; 47: 79-82
93. Aghel A, Shrestha K, Mullens W et al. Serum neutrophil gelatinase-associated lipocalin (NGAL) in predicting worsening renal function in acute decompensated heart failure. J Card Fail 2010; 16: 49-54
94. Martensson J, Bell M, Oldner A et al. Neutrophil gelatinase-associated lipocalin in adult septic patients with and without acute kidney injury. Intensive Care Med 2010; 36: 1333-1340
95. Yang HN, Boo CS, Kim MG et al. Urine neutrophil gelatinaseassociated lipocalin: an independent predictor of adverse outcomes in acute kidney injury. Am J Nephrol 2010; 31: 501-509
96. Parikh CR, Abraham E, Ancukiewicz M et al. Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. J Am Soc Nephrol 2005; 16: 3046-3052 (Pubitemid 44743502)
97. Westhuyzen J, Endre ZH, Reece G et al. Measurement of tubular enzymuria facilitates early detection of acute renal impairment in the intensive care unit. Nephrol Dial Transplant 2003; 18: 543-551 (Pubitemid 36305660)
98. Iglesias J, Marik PE, Levine JS. Elevated serum levels of the type I and type II receptors for tumor necrosis factor-alpha as predictive factors for ARF in patients with septic shock. Am J Kidney Dis 2003; 41: 62-75 (Pubitemid 36043352)
99. Liu KD, Glidden DV, Eisner MD et al. Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Crit Care Med 2007; 35: 2755-2761
100. Walshe CM, Odejayi F, Ng S et al. Urinary glutathione S-transferase as an early marker for renal dysfunction in patients admitted to intensive care with sepsis. Crit Care Resusc 2009; 11: 204-209
101. Matsui K, Kamijo-Ikemori A, Hara M et al. Clinical significance of tubular and podocyte biomarkers in acute kidney injury. Clin Exp Nephrol 2011; 15: 220-225
102. Blasco V, Wiramus S, Textoris J et al. Monitoring of plasma creatinine and urinary gamma-glutamyl transpeptidase improves detection of acute kidney injury by more than 20%. Crit Care Med 2011; 39: 52-56
103. Nakamura T, Sugaya T, Node K et al. Urinary excretion of livertype fatty acid-binding protein in contrast medium-induced nephropathy. Am J Kidney Dis 2006; 47: 439-444 (Pubitemid 43255177)
104. Bachorzewska-Gajewska H, Malyszko J, Sitniewska E et al. Could neutrophil-gelatinase-associated lipocalin and cystatin C predict the development of contrast-induced nephropathy after percutaneous coronary interventions in patients with stable angina and normal serum creatinine values? Kidney Blood Press Res 2007; 30: 408-415. (Pubitemid 350191437)
105. Shaker OG, El-Shehaby A, El-Khatib M. Early diagnostic markers for contrast nephropathy in patients undergoing coronary angiography. Angiology 2010; 61: 731-736
106. Kato K, Sato N, Yamamoto T et al. Valuable markers for contrastinduced nephropathy in patients undergoing cardiac catheterization. Circ J 2008; 72: 1499-1505
107. Briguori C, Visconti G, Rivera NV et al. Cystatin C and contrastinduced acute kidney injury. Circulation 2010; 121: 2117-2122
108. Ishibashi Y, Yamauchi M, Musha H et al. Impact of contrastinduced nephropathy and cardiovascular events by serum cystatin C in renal insufficiency patients undergoing cardiac catheterization. Angiology 2010; 61: 724-730