In vitro evaluation of biomarkers for cisplatin-induced nephrotoxicity using HK-2 human kidney epithelial cells

Toxicology Letters

Volumn 217, Issue 3, 2013, Pages 235-242

  Sohn, So Jung ^a   Kim, Sun Young ^a   Kim, Hyung Sik ^b   Chun, Young Jin ^c   Han, Soon Young ^d   Kim, Seung Hee ^d   Moon, Aree ^a  

^a Duksung Women's University   (South Korea)

^b Pusan National University   (South Korea)

^c Chung Ang University   (South Korea)

^d Korea Food and Drug Administration   (South Korea)

Author keywords

Biomarker; Calbindin; HK 2; KIM 1; Nephrotoxicity; TIMP 1

Indexed keywords

BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; CALBINDIN; CASPASE 3; CISPLATIN; CLUSTERIN; CYSTATIN C; KIDNEY INJURY MOLECULE 1; MESSENGER RNA; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROTEIN BCL 2; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY EPITHELIUM; KIDNEY PROXIMAL TUBULE; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSCRIPTION INITIATION; UPREGULATION; URINE; VALIDATION PROCESS;

ANIMALS; ANTINEOPLASTIC AGENTS; BETA 2-MICROGLOBULIN; BIOLOGICAL MARKERS; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CELL LINE; CISPLATIN; CLUSTERIN; CYSTATIN C; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; KIDNEY; KIDNEY DISEASES; MALE; MEMBRANE GLYCOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, VIRUS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 84874002466     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.12.015     Document Type: Article

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