In vitro nephrotoxicity induced by propanil

Environmental Toxicology

Volumn 23, Issue 4, 2008, Pages 435-442

  Rankin, Gary O ^a   Racine, Christopher ^a   Sweeney, Adam ^a   Kraynie, Alyssa ^a   Anestis, Dianne K ^a   Barnett, John B ^b  

^a MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Fischer 344 rats; Halogenated hydrocarbons; Herbicides; In vitro; Kidney; Nephrotoxicity

Indexed keywords

AGRICULTURAL PRODUCTS; BIOMOLECULES; FATTY ACIDS; HERBICIDES; HYDROLYSIS; METABOLITES;

CORTICAL CELLS; CYCLO-OXYGENASE (COX); CYTOCHROME P450 (CYP); DICHLOROANILINE; FLAVIN ADENINE DINUCLEOTIDE (FAD); IMMUNOTOXICITY; IN-VITRO; IN-VIVO; LACTATE DEHYDROGENASE (LDH); MECHANISTIC ASPECTS; MONOOXYGENASE; NEPHROTOXICITY; PIPERONYL BUTOXIDE; PRE TREATMENTS; PROPANIL; PROPIONIC ACIDS; UNITED STATES; WHEAT PRODUCTION;

CYTOTOXICITY;

3,4 DICHLOROANILINE; ALPHA TOCOPHEROL; ASCORBIC ACID; CYTOCHROME P450; DEFEROXAMINE; FLAVIN ADENINE DINUCLEOTIDE MONOOXYGENASE; GLUTATHIONE; INDOMETACIN; ISONIAZID; LACTATE DEHYDROGENASE; METYRAPONE; OCTYLAMINE; PIPERONYL BUTOXIDE; PROPANIL; PROPIONIC ACID; PROSTAGLANDIN SYNTHASE; THIAMAZOLE; UNSPECIFIC MONOOXYGENASE;

ENZYME ACTIVITY; HERBICIDE; HYDROLYSIS; INHIBITION; METABOLITE; POLLUTION EXPOSURE; TOXICITY TEST;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; FISCHER 344 RAT; HYDROLYSIS; KIDNEY CELL; KIDNEY CORTEX; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; HERBICIDES; KIDNEY CORTEX; MALE; MOLECULAR STRUCTURE; OXIDATIVE STRESS; PROPANIL; RATS; RATS, INBRED F344;

RATTUS; TRITICUM AESTIVUM;

EID: 47549104080     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20353     Document Type: Article

References (37)

1. Ambrose AM, Larson PS, Borzelleca JF, Hennigar GR Jr. 1972. Toxicological studies on 3′,4′-dichloropropioanilide Toxicol Appl Pharmacol 23:650-659.
2. Aubrecht J, Hirsch-Ernst KI, Foth H, Kahl GF, Hohne MW. 1996. Differential induction of mRNA expression of cytochromes P450 (CYP2B1 and CYP1A1/2) by metyrapone in primary rat hepatocytes. Res Commun Mol Pathol Pharmacol 94:47-61.
3. Baliga R, Zhang Z, Baliga M, Ueda N, Shah SV. 1998. Role of cytochrome P-450 as a source of catalytic iron in cisplatin-induced nephrotoxicity. Kidney Int 54:1562-1569.
4. Barnett JB, Gandy J, Wilbourn D, Theus SA. 1992. Comparison of the immunotoxicity of propanil and its metabolite, 3,4-dichloroaniline, in C57B1/6 mice. Fundam Appl Toxicol 18:628-631.
5. Bartha R, Pramer D. 1970. Metabolism of acrylanilide herbicides. Adv Appl Microbiol 13:317-341.
6. Blyler G, Landreth KS, Lillis T, Schafer R, Theus SA, Gandy J, Barnett JB. 1994. Selective myleotoxicity of propanil. Fundam Appl Toxicol 22:505-510.
7. Chow AYK, Murphy SD. 1975. Propanil (3,4-dichloropropionanilide)-induced methemoglobin formation in relation to its metabolism in vitro. Toxicol Appl Pharmacol 33:14-20.
8. De Silva WAS, Bodinayake CK. 1997. Propanil poisoning. Ceylon Med J 42:81-84.
9. Duringer JM, Buhler DR, Craig AM. 2004. Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle. Am J Vet Res 65:1563-1572.
10. Eddieston M, Rajapakshe M, Roberts D, Reginald K, Rezvi Sheriff MH, Dissanayake W, Buckley N. 2002. Severe propanil [N-(3, 4-dicholorophenyl)propanamide] pesticide self-poisoning. J Toxicol Clin Toxicol 40:847-854.
11. Frost LL, Neeley YX, Schafer R, Gibson LF, Barnett JB. 2001. Propanil inhibits tumor necrosis factor-α production by reducing nuclear levels of the transcription factor nuclear factor-κB in the macrophage cell line IC-21. Toxicol Appl Pharmacol 172:185-193.
12. Guilhermino L, Soares AMVM, Carvalho AP, Lopes MC. 1998. Acute effects of 3,4-dichloroaniline on blood of male Wistar mice. Chemosphere 37:619-632.
13. Jones DP, Sundby G-B, Ormsted K, Orrenius S. 1979. Use of isolated kidney cells for study of drug metabolism. Biochem Pharmacol 28:929-935.
14. Kajita J, Inano K, Fuse E, Kuwabara T, Kobayashi H. 2002. Effects of olopatadine, a new antiallergic agent, on human liver microsomal cytochrome P450 activities. Drug Metab Dispos 30:1504-1511.
15. Kimbrough RD. 1980. Human health effects of selected pesticides, chloroaniline derivatives. J Environ Sci Health 15:972-992.
16. Lash LH, Tokarz JJ. 1989. Isolation of two distinct populations of cells from rat kidney cortex and their use in the study of chemical-induced toxicity. Anal Biochem 182:271-279.
17. Lo H-H, Brown PI, Rankin GO. 1990. Acute nephrotoxicity induced by isomeric dichloroanilines in Fischer 344 rats. Toxicology 63:215-231.
18. Lock EA, Reed CJ. 1998. Xenobiotic metabolizing enzymes of the kidney. Toxicol Pathol 26:18-25.
19. Lock EA, Cross TJ, Schnellmann RG. 1993. Studies on the mechanism of 4-aminophenol-induced toxicity to renal proximal tubules. Hum Exp Toxicol 12:383-388.
20. Malejka-Giganti D, Ritter CL. 1994. Peroxidative metabolism of carcinogenic N-arylhydroxamic acids: Implications for tumorigenesis. Environ Health Perspect 102 (Suppl 6):75-81.
21. Malerba I, Castoldi AF, Parent-Massin D, Gribaldo L. 2002. In vitro myleotoxicity of propanil and 3,4-dichloroaniline on murine and human CFU-E/BFU-E progenitors. Toxicol Sci 69:433-438.
22. McMillan DC, Freeman JP, Hinson JA. 1990a. Metabolism of the arylamide herbicide propanil. I. Microsomal metabolism and in vitro methemoglobinemia. Toxicol Appl Pharmacol 103:90-101.
23. McMillan DC, McRae TA, Hinson JA. 1990b. Propanil-induced methemoglobinemia and hemoglobin binding in the rat. Toxicol Appl Pharmacol 105:503-507.
24. McMillan DC, Bradshaw TP, Hinson JA, Jollow DJ. 1991. Role of metabolites in propanil-induced hemolytic anemia. Toxicol Appl Pharmacol 110:70-78.
25. Morse DL, Baker EL Jr. 1979. Propanil-chloracne and methomyl toxicity in workers of a pesticide manufacturing plant. Clin Toxicol 15:13-21.
26. Mulder GJ, Meerman JH. 1983. Sulfation and glucuronidation as competing pathways in the metabolism of hydroxamic acids: the role of N.O-sulfation in chemical carcinogenesis of aromatic amines. Environ Health Perspect 49:27-32.
27. O'Brien PJ, Siraki AG. 2005. Accelerated cytotoxicity mechanism screening using drug metabolizing enzyme modulators. Curr Drug Metab 6:101-109.
28. Rodriguez RJ, Acosta D Jr. 1997. N-Deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes. Toxicology 117:123-131.
29. Santillo M, Rippa C, Della Morte R, Villani GR, Santangelo F, Staiano N, Mondola P. 1995. Enhancement of tissue lipoperoxidation in propanil-treated rats. Toxicol Lett 78:215-218.
30. Singleton SD, Murphy SD. 1973. Propanil (3,4-dichloropropionanilide)- induced methemoglobin formation in mice in relation to acylamidase activity Toxicol Appl Pharmacol 25:20-29.
31. Valentovic MA, Ball JG, Anestis DK, Rankin GO. 1995. Comparison of the in vitro toxicity of dichloroaniline structural isomers. Toxicol In Vitro 9:75-81.
32. Valentovic M, Meadows MK, Harmon RC, Ball JG, Hong SK, Rankin GO. 1999. 2-Amino-5-chlorophenol toxicity in renal cortical slices from Fischer 344 rats: Effects of antioxidants and sulfhydryl agents. Toxicol Appl Pharmacol 161:1-9.
33. Valentovic M, Ball JG, Stoll S, Rankin GO. 2001. 3,4- Dichlorophenylhydroxylamine cytotoxicity in renal cortical slices from Fischer 344 rats. Toxicology 162:149-156.
34. Valentovic MA, Ball JG, Sun H, Rankin GO. 2002. Characterization of 2-amino-4,5-dichlorophenol (2A45CP) in vitro toxicity in renal cortical slices from male Fischer 344 rats. Toxicology 172:113-123.
35. Wassenberg DM, Di Giulio RT. 2004. Teratogenesis in Fundulus heteroclitus embryos exposed to a creosote-contaminated sediment extract and CYP1A inhibitors. Mar Environ Res 58:163-168.
36. Wijekoon PNB, Sivaramakrishna N, Nimalasuriya A. 1974. Acute haemolysis and renal failure in chlorinated hydrocarbon poisoning. Ceylon Med J 19:37-38.
37. Yamazaki M, Terada M, Kuroki H, Honda K, Matoba R, Mitsukuni Y. 2001. Pesticide poisoning initially suspected as a natural death. J Forensic Sci 46:165-170.