Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1β, IL-18, IL-6, and neutrophil infiltration in the kidney

Journal of Pharmacology and Experimental Therapeutics

Volumn 322, Issue 1, 2007, Pages 8-15

  Faubel, Sarah ^a   Lewis, Eli C ^a   Reznikov, Leonid ^a   Ljubanovic, Danica ^b   Hoke, Thomas S ^a   Somerset, Hilary ^a   Oh, Dong Jin ^a   Lu, Lawrence ^a   Klein, Christina L ^a   Dinarello, Charles A ^a   Edelstein, Charles L ^a,c  

^a UNIVERSITY OF COLORADO   (United States)

^b University of Zagreb School of Medicine   (Croatia)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CASPASE 1; CISPLATIN; INTERLEUKIN-18; INTERLEUKIN-1BETA; INTERLEUKIN-6; KIDNEY; KIDNEY FAILURE, ACUTE; MALE; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; NEUTROPHILS;

EID: 34250765336     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.119792     Document Type: Article

References (31)

1. Aiura K, Gelfand JA, Burke JF, Thompson RC, and Dinarello CA (1993) Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits. Infect Immun 61:3342-3350.
2. Akira S (2000) The role of IL-18 in innate immunity. Curr Opin Immunol 12:59-63.
3. Daemen MA, Van't Veer C, Wolfs TG, and Buurman WA (1999) Ischemia-reperfusion-induced IFN-gamma up-regulation: involvement of IL-12 and IL-18. J Immunol 162:5506-5510.
4. Deng J, Kohda Y, Chiao H, Wang Y, Hu X, Hewitt SM, Miyaji T, McLeroy P, Nibhanupudy B, Li S, et al. (2001) Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury. Kidney Int 60:2118-2128.
5. Fantuzzi G, Banda NK, Guthridge C, Vondracek A, Kim SH, Siegmund B, Azam T, Sennello JA, Dinarello CA, and Arend WP (2003) Generation and characterization of mice transgenic for human IL-18-binding protein isoform a. J Leukoc Biol 74:889-896.
6. Fantuzzi G, Reed DA, and Dinarello CA (1999) IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor. J Clin Invest 104:761-767.
7. Faubel SG, Ljubanovic D, Reznikov LL, Somerset H, Dinarello CA, and Edelstein CL (2004) Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis. Kidney Int 66:2202-2213.
8. Gu Y, Kuida K, Tsutsui H, Ku G, Hsiao K, Fleming MA, Hayashi N, Higashino K, Okamura H, Nakanishi K, et al. (1997) Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science 275:206-209.
9. Haq M, Norman J, Saba SR, Ramirez G, and Rabb H (1998) Role of IL-1 in renal ischemic reperfusion injury. J Am Soc Nephrol 9:614-619.
10. Kelly KJ, Meehan SM, Colvin RB, Williams WW, and Bonventre JV (1999) Protection from toxicant-mediated renal injury in the rat with anti-CD54 antibody. Kidney Int 56:922-931.
11. Kinjo Y, Kawakami K, Uezu K, Yara S, Miyagi K, Koguchi Y, Hoshino T, Okamoto M, Kawase Y, Yokota K, et al. (2002) Contribution of IL-18 to Th1 response and host defense against infection by Mycobacterium tuberculosis: a comparative study with IL-12p40. J Immunol 169:323-329.
12. Koedel U, Winkler F, Angele B, Fontana A, Flavell RA, and Pfister HW (2002) Role of caspase-1 in experimental pneumococcal meningitis: evidence from pharmacologic caspase inhibition and caspase-1-deficient mice. Ann Neurol 51:319-329.
13. Kuida K, Lippke JA, Ku G, Harding MW, Livingston DJ, Su MSS, and Flavell RA (1995) Altered cytokine export and apoptosis in mice deficient in interleukin-1B converting enzyme. Science 267:2000-2002.
14. Li P, Allen H, Banerjee S, Franklin S, Herzog L, Johnston C, McDowell J, Paskind M, Rodman L, and Salfeld J (1995) Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 80:401-411.
15. Li P, Allen H, Banerjee S, and Seshadri T (1997) Characterization of mice deficient in interleukin-1 beta converting enzyme. J Cell Biochem 64:27-32.
16. Li S, Gokden N, Okusa MD, Bhatt R, and Portilla D (2005) Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF. Am J Physiol 289:F469-F480.
17. Liu M, Chien CC, Burne-Taney M, Molls RR, Racusen LC, Colvin RB, and Rabb H (2006) A pathophysiologic role for T lymphocytes in murine acute cisplatin nephrotoxicity. J Am Soc Nephrol 17:765-774.
18. Liu XH, Kwon D, Schielke GP, Yang GY, Silverstein FS, and Barks JD (1999) Mice deficient in interleukin-1 converting enzyme are resistant to neonatal hypoxic-ischemic brain damage. J Cereb Blood Flow Metab 19:1099-1108.
19. Melnikov VY, Ecder T, Fantuzzi G, Siegmund B, Lucia MS, Dinarello CA, Schrier RW, and Edelstein CL (2001) Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. J Clin Invest 107:1145-1152.
20. Melnikov VY, Faubel SG, Siegmund B, Lucia MS, Ljubanovic D, and Edelstein CL (2002) Neutrophil-independent mechanisms of caspase-1- and IL-18-mediated ischemic acute tubular necrosis in mice. J Clin Invest 110:1083-1091.
21. Nakamura S, Kashimoto S, Kajikawa F, and Nakata K (1991) Combination effect of recombinant human interleukin 1 alpha with antitumor drugs on syngeneic tumors in mice. Cancer Res 51:215-221.
22. Nakanishi K, Yoshimoto T, Tsutsui H, and Okamura H (2001) Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev 12:53-72.
23. Okamoto M, Ohe G, Oshikawa T, Nishikawa H, Furuichi S, Yoshida H, and Sato M (2000) Induction of cytokines and killer cell activities by cisplatin and 5-fluorouracil in head and neck cancer patients. Anti-Cancer Drugs 11:165-173.
24. Ramesh G and Reeves WB (2002) TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity. J Clin Invest 110:835-842.
25. Ramesh G and Reeves WB (2003) TNFR2-mediated apoptosis and necrosis in cisplatin-induced acute renal failure. Am J Physiol 285:F610-F618.
26. Safirstein RL (2007) Renal disease induced by anti-neoplastic agents, in Diseases of the Kidney and Urinary Tract (Schrier RW ed) pp 1068-1081, Lippincott, Williams & Wilkins, Philadelphia.
27. Schrier RW (2002) Cancer therapy and renal injury. J Clin Invest 110:743-745.
28. Siegmund B, Lehr HA, Fantuzzi G, and Dinarello CA (2001) IL-1 beta-converting enzyme (caspase-1) in intestinal inflammation. Proc Natl Acad Sci USA 98:13249-13254.
29. Wang W, Faubel SG, Ljubanovic D, Mitra A, Kim J, Tao Y, Soloviev A, Reznikov L, Dinarello CA, Schrier RW, et al. (2005) Endotoxemic acute renal failure is attenuated in caspase-1 deficient mice. Am J Physiol 288:F997-F1004.
30. Werman A, Werman-Venkert R, White R, Lee JK, Werman B, Krelin Y, Voronov E, Dinarello CA, and Apte RN (2004) The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription. Proc Natl Acad Sci USA 101:2434-2439.
31. Wipke BT and Allen PM (2001) Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J Immunol 167:1601-1608.