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Volumn 6, Issue 7, 2011, Pages

Sensitive and specific fluorescent probes for functional analysis of the three major types of Mammalian ABC transporters

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER INHIBITOR; BREAST CANCER RESISTANCE PROTEIN; CALCEIN AM; CYCLOSPORIN A; DAUNORUBICIN; DOXORUBICIN; FLUORESCENT DYE; FUMITREMORGIN C; GLYCOPROTEIN P; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; PHEOPHORBIDE; PHEOPHORBIDE A; PROTEIN INHIBITOR; RHODAMINE 123; UNCLASSIFIED DRUG; VERLUKAST; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

EID: 79960675115     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022429     Document Type: Article
Times cited : (74)

References (37)
  • 1
    • 0141888537 scopus 로고    scopus 로고
    • The role of ABC transporters in clinical practice
    • Leonard GD, Fojo T, Bates SE, (2003) The role of ABC transporters in clinical practice. Oncologist 8: 411-424.
    • (2003) Oncologist , vol.8 , pp. 411-424
    • Leonard, G.D.1    Fojo, T.2    Bates, S.E.3
  • 2
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE, (2002) Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2: 48-58.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 3
    • 1242335471 scopus 로고    scopus 로고
    • The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation
    • Haimeur A, Conseil G, Deeley RG, Cole SP, (2004) The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation. Curr Drug Metab 5: 21-53.
    • (2004) Curr Drug Metab , vol.5 , pp. 21-53
    • Haimeur, A.1    Conseil, G.2    Deeley, R.G.3    Cole, S.P.4
  • 4
    • 8944261743 scopus 로고    scopus 로고
    • Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations
    • Beck WT, Grogan TM, Willman CL, Cordon-Cardo C, Parham DM, et al. (1996) Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. Cancer Res 56: 3010-3020.
    • (1996) Cancer Res , vol.56 , pp. 3010-3020
    • Beck, W.T.1    Grogan, T.M.2    Willman, C.L.3    Cordon-Cardo, C.4    Parham, D.M.5
  • 5
    • 0023833803 scopus 로고
    • Use of fluorescent dyes as molecular probes for the study of multidrug resistance
    • Neyfakh AA, (1988) Use of fluorescent dyes as molecular probes for the study of multidrug resistance. Exp Cell Res 174: 168-176.
    • (1988) Exp Cell Res , vol.174 , pp. 168-176
    • Neyfakh, A.A.1
  • 6
    • 0034947674 scopus 로고    scopus 로고
    • From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
    • Litman T, Druley TE, Stein WD, Bates SE, (2001) From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell Mol Life Sci 58: 931-959.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 931-959
    • Litman, T.1    Druley, T.E.2    Stein, W.D.3    Bates, S.E.4
  • 7
    • 0028332661 scopus 로고
    • Calcein accumulation as a fluorometric functional assay of the multidrug transporter
    • Hollo Z, Homolya L, Davis CW, Sarkadi B, (1994) Calcein accumulation as a fluorometric functional assay of the multidrug transporter. Biochim Biophys Acta 1191: 384-388.
    • (1994) Biochim Biophys Acta , vol.1191 , pp. 384-388
    • Hollo, Z.1    Homolya, L.2    Davis, C.W.3    Sarkadi, B.4
  • 8
    • 0027432409 scopus 로고
    • Fluorescent cellular indicators are extruded by the multidrug resistance protein
    • Homolya L, Hollo Z, Germann UA, Pastan I, Gottesman MM, et al. (1993) Fluorescent cellular indicators are extruded by the multidrug resistance protein. J Biol Chem 268: 21493-21496.
    • (1993) J Biol Chem , vol.268 , pp. 21493-21496
    • Homolya, L.1    Hollo, Z.2    Germann, U.A.3    Pastan, I.4    Gottesman, M.M.5
  • 9
    • 0028365179 scopus 로고
    • Microfluorometric evaluation of calcein acetoxymethyl ester as a probe for P-glycoprotein-mediated resistance: effects of cyclosporin A and its nonimmunosuppressive analogue SDZ PSC 833
    • Liminga G, Nygren P, Larsson R, (1994) Microfluorometric evaluation of calcein acetoxymethyl ester as a probe for P-glycoprotein-mediated resistance: effects of cyclosporin A and its nonimmunosuppressive analogue SDZ PSC 833. Exp Cell Res 212: 291-296.
    • (1994) Exp Cell Res , vol.212 , pp. 291-296
    • Liminga, G.1    Nygren, P.2    Larsson, R.3
  • 11
    • 0034081847 scopus 로고    scopus 로고
    • The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)
    • Litman T, Brangi M, Hudson E, Fetsch P, Abati A, et al. (2000) The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2). J Cell Sci 113(Pt 11): 2011-2021.
    • (2000) J Cell Sci , vol.113 , Issue.PT 11 , pp. 2011-2021
    • Litman, T.1    Brangi, M.2    Hudson, E.3    Fetsch, P.4    Abati, A.5
  • 12
    • 61649095448 scopus 로고    scopus 로고
    • Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide
    • van der Heijden JW, Oerlemans R, Tak PP, Assaraf YG, Kraan MC, et al. (2009) Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide. Arthritis Rheum 60: 669-677.
    • (2009) Arthritis Rheum , vol.60 , pp. 669-677
    • van der Heijden, J.W.1    Oerlemans, R.2    Tak, P.P.3    Assaraf, Y.G.4    Kraan, M.C.5
  • 13
    • 0345688604 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
    • Doyle LA, Ross DD, (2003) Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2). Oncogene 22: 7340-7358.
    • (2003) Oncogene , vol.22 , pp. 7340-7358
    • Doyle, L.A.1    Ross, D.D.2
  • 14
    • 0029793039 scopus 로고    scopus 로고
    • Ranking of P-glycoprotein substrates and inhibitors by a calcein-AM fluorometry screening assay
    • Tiberghien F, Loor F, (1996) Ranking of P-glycoprotein substrates and inhibitors by a calcein-AM fluorometry screening assay. Anticancer Drugs 7: 568-578.
    • (1996) Anticancer Drugs , vol.7 , pp. 568-578
    • Tiberghien, F.1    Loor, F.2
  • 16
    • 54749126264 scopus 로고    scopus 로고
    • P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response
    • McCollum AK, TenEyck CJ, Stensgard B, Morlan BW, Ballman KV, et al. (2008) P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response. Cancer Res 68: 7419-7427.
    • (2008) Cancer Res , vol.68 , pp. 7419-7427
    • McCollum, A.K.1    TenEyck, C.J.2    Stensgard, B.3    Morlan, B.W.4    Ballman, K.V.5
  • 17
    • 0037079708 scopus 로고    scopus 로고
    • The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
    • Scharenberg CW, Harkey MA, Torok-Storb B, (2002) The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood 99: 507-512.
    • (2002) Blood , vol.99 , pp. 507-512
    • Scharenberg, C.W.1    Harkey, M.A.2    Torok-Storb, B.3
  • 18
    • 0023917686 scopus 로고
    • Intrinsic multidrug resistance phenotype of Chinese hamster (rodent) cells in comparison to human cells
    • Gupta RS, (1988) Intrinsic multidrug resistance phenotype of Chinese hamster (rodent) cells in comparison to human cells. Biochem Biophys Res Commun 153: 598-605.
    • (1988) Biochem Biophys Res Commun , vol.153 , pp. 598-605
    • Gupta, R.S.1
  • 20
    • 0026650170 scopus 로고
    • Polarized efflux of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein from cultured epithelial cell monolayers
    • Collington GK, Hunter J, Allen CN, Simmons NL, Hirst BH, (1992) Polarized efflux of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein from cultured epithelial cell monolayers. Biochem Pharmacol 44: 417-424.
    • (1992) Biochem Pharmacol , vol.44 , pp. 417-424
    • Collington, G.K.1    Hunter, J.2    Allen, C.N.3    Simmons, N.L.4    Hirst, B.H.5
  • 21
    • 0025912228 scopus 로고
    • Epithelial secretion of vinblastine by human intestinal adenocarcinoma cell (HCT-8 and T84) layers expressing P-glycoprotein
    • Hunter J, Hirst BH, Simmons NL, (1991) Epithelial secretion of vinblastine by human intestinal adenocarcinoma cell (HCT-8 and T84) layers expressing P-glycoprotein. Br J Cancer 64: 437-444.
    • (1991) Br J Cancer , vol.64 , pp. 437-444
    • Hunter, J.1    Hirst, B.H.2    Simmons, N.L.3
  • 22
    • 0028915934 scopus 로고
    • Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen
    • Alvarez M, Paull K, Monks A, Hose C, Lee JS, et al. (1995) Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen. J Clin Invest 95: 2205-2214.
    • (1995) J Clin Invest , vol.95 , pp. 2205-2214
    • Alvarez, M.1    Paull, K.2    Monks, A.3    Hose, C.4    Lee, J.S.5
  • 23
    • 0033998261 scopus 로고    scopus 로고
    • MRP2, a human conjugate export pump, is present and transports fluo 3 into apical vacuoles of Hep G2 cells
    • Cantz T, Nies AT, Brom M, Hofmann AF, Keppler D, (2000) MRP2, a human conjugate export pump, is present and transports fluo 3 into apical vacuoles of Hep G2 cells. Am J Physiol Gastrointest Liver Physiol 278: G522-531.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.278 , pp. 522-531
    • Cantz, T.1    Nies, A.T.2    Brom, M.3    Hofmann, A.F.4    Keppler, D.5
  • 24
    • 0031058993 scopus 로고    scopus 로고
    • Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells
    • Roelofsen H, Vos TA, Schippers IJ, Kuipers F, Koning H, et al. (1997) Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells. Gastroenterology 112: 511-521.
    • (1997) Gastroenterology , vol.112 , pp. 511-521
    • Roelofsen, H.1    Vos, T.A.2    Schippers, I.J.3    Kuipers, F.4    Koning, H.5
  • 25
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T, (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 26
    • 0017690690 scopus 로고
    • Proof without prejudice: use of the Kolmogorov-Smirnov test for the analysis of histograms from flow systems and other sources
    • Young IT, (1977) Proof without prejudice: use of the Kolmogorov-Smirnov test for the analysis of histograms from flow systems and other sources. J Histochem Cytochem 25: 935-941.
    • (1977) J Histochem Cytochem , vol.25 , pp. 935-941
    • Young, I.T.1
  • 27
    • 0030848067 scopus 로고    scopus 로고
    • Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia
    • Broxterman HJ, Lankelma J, Pinedo HM, Eekman CA, Wahrer DC, et al. (1997) Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia. Leukemia 11: 1110-1118.
    • (1997) Leukemia , vol.11 , pp. 1110-1118
    • Broxterman, H.J.1    Lankelma, J.2    Pinedo, H.M.3    Eekman, C.A.4    Wahrer, D.C.5
  • 28
    • 9344264652 scopus 로고    scopus 로고
    • Quality control of multidrug resistance assays in adult acute leukemia: correlation between assays for P-glycoprotein expression and activity
    • Broxterman HJ, Sonneveld P, Feller N, Ossenkoppele GJ, Wahrer DC, et al. (1996) Quality control of multidrug resistance assays in adult acute leukemia: correlation between assays for P-glycoprotein expression and activity. Blood 87: 4809-4816.
    • (1996) Blood , vol.87 , pp. 4809-4816
    • Broxterman, H.J.1    Sonneveld, P.2    Feller, N.3    Ossenkoppele, G.J.4    Wahrer, D.C.5
  • 29
    • 33749488939 scopus 로고    scopus 로고
    • Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system
    • Sarkadi B, Homolya L, Szakacs G, Varadi A, (2006) Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol Rev 86: 1179-1236.
    • (2006) Physiol Rev , vol.86 , pp. 1179-1236
    • Sarkadi, B.1    Homolya, L.2    Szakacs, G.3    Varadi, A.4
  • 30
    • 33846794508 scopus 로고    scopus 로고
    • About a switch: how P-glycoprotein (ABCB1) harnesses the energy of ATP binding and hydrolysis to do mechanical work
    • Sauna ZE, Ambudkar SV, (2007) About a switch: how P-glycoprotein (ABCB1) harnesses the energy of ATP binding and hydrolysis to do mechanical work. Mol Cancer Ther 6: 13-23.
    • (2007) Mol Cancer Ther , vol.6 , pp. 13-23
    • Sauna, Z.E.1    Ambudkar, S.V.2
  • 31
    • 0029658513 scopus 로고    scopus 로고
    • DiOC2(3) is not a substrate for multidrug resistance protein (MRP)-mediated drug efflux
    • Minderman H, Vanhoefer U, Toth K, Yin MB, Minderman MD, et al. (1996) DiOC2(3) is not a substrate for multidrug resistance protein (MRP)-mediated drug efflux. Cytometry 25: 14-20.
    • (1996) Cytometry , vol.25 , pp. 14-20
    • Minderman, H.1    Vanhoefer, U.2    Toth, K.3    Yin, M.B.4    Minderman, M.D.5
  • 32
    • 1242293677 scopus 로고    scopus 로고
    • Pheophorbide a is a specific probe for ABCG2 function and inhibition
    • Robey RW, Steadman K, Polgar O, Morisaki K, Blayney M, et al. (2004) Pheophorbide a is a specific probe for ABCG2 function and inhibition. Cancer Res 64: 1242-1246.
    • (2004) Cancer Res , vol.64 , pp. 1242-1246
    • Robey, R.W.1    Steadman, K.2    Polgar, O.3    Morisaki, K.4    Blayney, M.5
  • 33
    • 0033518874 scopus 로고    scopus 로고
    • Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines
    • Ross DD, Yang W, Abruzzo LV, Dalton WS, Schneider E, et al. (1999) Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines. J Natl Cancer Inst 91: 429-433.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 429-433
    • Ross, D.D.1    Yang, W.2    Abruzzo, L.V.3    Dalton, W.S.4    Schneider, E.5
  • 34
    • 0024353128 scopus 로고
    • Multidrug resistance in mitoxantrone-selected HL-60 leukemia cells in the absence of P-glycoprotein overexpression
    • Harker WG, Slade DL, Dalton WS, Meltzer PS, Trent JM, (1989) Multidrug resistance in mitoxantrone-selected HL-60 leukemia cells in the absence of P-glycoprotein overexpression. Cancer Res 49: 4542-4549.
    • (1989) Cancer Res , vol.49 , pp. 4542-4549
    • Harker, W.G.1    Slade, D.L.2    Dalton, W.S.3    Meltzer, P.S.4    Trent, J.M.5
  • 35
    • 0033966957 scopus 로고    scopus 로고
    • Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
    • Rabindran SK, Ross DD, Doyle LA, Yang W, Greenberger LM, (2000) Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res 60: 47-50.
    • (2000) Cancer Res , vol.60 , pp. 47-50
    • Rabindran, S.K.1    Ross, D.D.2    Doyle, L.A.3    Yang, W.4    Greenberger, L.M.5
  • 36
    • 0029958849 scopus 로고    scopus 로고
    • Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells
    • Hollo Z, Homolya L, Hegedus T, Sarkadi B, (1996) Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells. FEBS Lett 383: 99-104.
    • (1996) FEBS Lett , vol.383 , pp. 99-104
    • Hollo, Z.1    Homolya, L.2    Hegedus, T.3    Sarkadi, B.4


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