Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: Roles of cytochrome c, Bax, Bid, and caspases

Toxicology and Applied Pharmacology

Volumn 191, Issue 2, 2003, Pages 118-129

  El Hassan, Hasan ^a   Anwar, Khurshid ^a   Macanas Pirard, Patricia ^a   Crabtree, Mark ^a   Chow, Sek C ^b   Johnson, Victoria L ^b   Lee, Pauline C ^c   Hinton, Richard H ^a   Price, Shirley C ^a   Kass, George E N ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Caspase; Fas; Hepatitis; Paracetamol; Permeability transition; TUNEL

Indexed keywords

ANTIBODY; BENZYLOXYCARBONYLPHENYLALANYLALANYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 7; CASPASE INHIBITOR; CYTOCHROME C; FAS ANTIGEN; PARACETAMOL; PROTEIN BAX; PROTEIN BID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EXPERIMENTAL MODEL; IMMUNOSTIMULATION; LIVER CYTOSOL; LIVER INJURY; LIVER PARENCHYMA; LIVER TOXICITY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PATHOGENESIS; PROPHYLAXIS;

EID: 0041733598     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(03)00240-0     Document Type: Article

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