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Volumn 77, Issue 7, 2003, Pages 365-370

Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells

Author keywords

C S lyase; Halogenated alkenes; Human proximal tubular cells; Rat proximal tubular cells

Indexed keywords

ALKENE DERIVATIVE; CYSTEINE CONJUGATE BETA LYASE; HALOGENATED HYDROCARBON; S (1,1,2,2 TETRAFLUOROETHYL)CYSTEINE; S (1,2 DICHLOROVINYL)CYSTEINE; S (2 CHLORO 1,1 DIFLUOROETHYL)CYSTEINE; S (TRICHLOROVINYL)CYSTEINE; UNCLASSIFIED DRUG;

EID: 0042159977     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-003-0459-6     Document Type: Article
Times cited : (45)

References (32)
  • 1
    • 0031748545 scopus 로고    scopus 로고
    • Glutathione-dependent bioactivation of haloalkenes
    • Anders MW, Dekant W (1998) Glutathione-dependent bioactivation of haloalkenes. Annu Rev Pharmacol Toxicol 38:501-537
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 501-537
    • Anders, M.W.1    Dekant, W.2
  • 2
    • 0023923003 scopus 로고
    • Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites
    • Anders MW, Lash LH, Dekant W, Elfarra AA, Dohn DR (1988) Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites. Crit Rev Toxicol 18:311-341
    • (1988) Crit Rev Toxicol , vol.18 , pp. 311-341
    • Anders, M.W.1    Lash, L.H.2    Dekant, W.3    Elfarra, A.A.4    Dohn, D.R.5
  • 3
    • 0027267051 scopus 로고
    • Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: Implications for the risk of trichloroethene exposure
    • Birner G, Vamvakas S, Dekant W, Henschler D (1993) Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure. Environ Health Perspect 99:281-284
    • (1993) Environ Health Perspect , vol.99 , pp. 281-284
    • Birner, G.1    Vamvakas, S.2    Dekant, W.3    Henschler, D.4
  • 4
    • 0023740342 scopus 로고
    • Formation of toxic metabolites from drugs and other xenobiotics by glutathione conjugation
    • Bladeren PJ van (1988) Formation of toxic metabolites from drugs and other xenobiotics by glutathione conjugation. Trends Pharmacol Sci 9:295-299
    • (1988) Trends Pharmacol Sci , vol.9 , pp. 295-299
    • Van Bladeren, P.J.1
  • 5
    • 0024447848 scopus 로고
    • Toxicity of the cysteine-S-conjugates and mercapturic acids of four structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney
    • Boogaard P, Commandeur JNM, Mulder GJ, Vermeulen NPE, Nagelkerke JF (1989) Toxicity of the cysteine-S-conjugates and mercapturic acids of four structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney. Biochem Pharmacol 38:3731-3741
    • (1989) Biochem Pharmacol , vol.38 , pp. 3731-3741
    • Boogaard, P.1    Commandeur, J.N.M.2    Mulder, G.J.3    Vermeulen, N.P.E.4    Nagelkerke, J.F.5
  • 6
    • 0026578111 scopus 로고
    • Species differences in the nephrotoxic response to S-(1,2-dichlorovinyl)glutathione
    • Chakrabarti S, Malick MA, Denniel C, Greselin E (1992) Species differences in the nephrotoxic response to S-(1,2-dichlorovinyl)glutathione. Toxicol Lett 60:343-351
    • (1992) Toxicol Lett , vol.60 , pp. 343-351
    • Chakrabarti, S.1    Malick, M.A.2    Denniel, C.3    Greselin, E.4
  • 7
    • 0025252253 scopus 로고
    • Renal cysteine conjugate β-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells
    • Chen JC, Stevens JL, Trifillis AL, Jones TW (1990) Renal cysteine conjugate β-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells. Toxicol Appl Pharmacol 103:463-473
    • (1990) Toxicol Appl Pharmacol , vol.103 , pp. 463-473
    • Chen, J.C.1    Stevens, J.L.2    Trifillis, A.L.3    Jones, T.W.4
  • 8
    • 0031616701 scopus 로고    scopus 로고
    • Mechanisms of cysteine S-conjugate β-lyases
    • Cooper AJL (1998) Mechanisms of cysteine S-conjugate β-lyases. Adv Enzymol 72A:199-238
    • (1998) Adv Enzymol , vol.72 A , pp. 199-238
    • Cooper, A.J.L.1
  • 9
    • 0022342783 scopus 로고
    • Nephrotoxicity of S-(2-chloro-1,1,2-trifluoroethyl)-glutathione and S-(2-chloro-1,1,2-trifluoro-ethyl)-L-cysteine, the glutathione and cysteine conjugates of chloro-trifluoroethene
    • Dohn DR, Leininger JR, Lash LH, Quebbemann AJ, Anders MW (1985) Nephrotoxicity of S-(2-chloro-1,1,2-trifluoroethyl)-glutathione and S-(2-chloro-1,1,2-trifluoro-ethyl)-L-cysteine, the glutathione and cysteine conjugates of chloro-trifluoroethene. J Pharmacol Exp Ther 235:851-857
    • (1985) J Pharmacol Exp Ther , vol.235 , pp. 851-857
    • Dohn, D.R.1    Leininger, J.R.2    Lash, L.H.3    Quebbemann, A.J.4    Anders, M.W.5
  • 10
    • 0022492563 scopus 로고
    • Mechanism of S-(1,2-dichlorovinyl)-glutathione-induced nephrotoxicity
    • Elfarra AA, Jakobson I, Anders MW (1986) Mechanism of S-(1,2-dichlorovinyl)-glutathione-induced nephrotoxicity. Biochem Pharmacol 35:283-283
    • (1986) Biochem Pharmacol , vol.35 , pp. 283
    • Elfarra, A.A.1    Jakobson, I.2    Anders, M.W.3
  • 12
    • 0021681724 scopus 로고
    • The metabolism and nephrotoxicity of tetrafluoroethylene in the rat
    • Green T, Odum J (1984) The metabolism and nephrotoxicity of tetrafluoroethylene in the rat. Toxicol Appl Pharmacol 76:306-318
    • (1984) Toxicol Appl Pharmacol , vol.76 , pp. 306-318
    • Green, T.1    Odum, J.2
  • 13
    • 0030800178 scopus 로고    scopus 로고
    • The role of glutathione conjugation in the development of kidney tumours m rats exposed to trichloroethylene
    • Green T, Dow J, Ellis MK, Foster JR, Odum J (1997) The role of glutathione conjugation in the development of kidney tumours m rats exposed to trichloroethylene. Chem Biol Interact 105:99-117
    • (1997) Chem Biol Interact , vol.105 , pp. 99-117
    • Green, T.1    Dow, J.2    Ellis, M.K.3    Foster, J.R.4    Odum, J.5
  • 14
    • 0022462523 scopus 로고
    • Nephrotoxicity of hexachlorobutadiene and its glutathione-derived conjugates
    • Ishmael J, Lock EA (1986) Nephrotoxicity of hexachlorobutadiene and its glutathione-derived conjugates. Toxicol Pathol 14:258-262
    • (1986) Toxicol Pathol , vol.14 , pp. 258-262
    • Ishmael, J.1    Lock, E.A.2
  • 15
    • 0024208162 scopus 로고
    • Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate beta-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity
    • Jones TW, Qin C, Schaeffer VH, Stevens JL (1988) Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate beta-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity. Mol Pharmacol 34:621-627
    • (1988) Mol Pharmacol , vol.34 , pp. 621-627
    • Jones, T.W.1    Qin, C.2    Schaeffer, V.H.3    Stevens, J.L.4
  • 16
    • 0031041496 scopus 로고    scopus 로고
    • Intranephron distribution of cysteine S-conjugate beta-lyase activity and its implication for hexachloro-1,3-butadiene induced nephrotoxicity in rats
    • Kim HS, Cha SH, Abraham DG, Cooper AJL, Endou H (1997) Intranephron distribution of cysteine S-conjugate beta-lyase activity and its implication for hexachloro-1,3-butadiene induced nephrotoxicity in rats. Arch Toxicol 71:131-141
    • (1997) Arch Toxicol , vol.71 , pp. 131-141
    • Kim, H.S.1    Cha, S.H.2    Abraham, D.G.3    Cooper, A.J.L.4    Endou, H.5
  • 17
    • 0031808523 scopus 로고    scopus 로고
    • Glutathione conjugation of perchloroethylene in rats and mice in vitro: Sex-, species-, and tissue-dependent differences
    • Lash LH, Qian W, Putt DA, Desai K, Elfarra AA, Sicuri AR, Parker JC (1998) Glutathione conjugation of perchloroethylene in rats and mice in vitro: sex-, species-, and tissue-dependent differences. Toxicol Appl Pharmacol 150:49-57
    • (1998) Toxicol Appl Pharmacol , vol.150 , pp. 49-57
    • Lash, L.H.1    Qian, W.2    Putt, D.A.3    Desai, K.4    Elfarra, A.A.5    Sicuri, A.R.6    Parker, J.C.7
  • 18
    • 0023761451 scopus 로고
    • Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes
    • Lock EA (1988) Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes. Crit Rev Toxicol 19:23-42
    • (1988) Crit Rev Toxicol , vol.19 , pp. 23-42
    • Lock, E.A.1
  • 19
    • 0022343447 scopus 로고
    • Effect of the organic acid transport inhibitor probenicid on renal cortical uptake and proximal tubular toxicity of hexachloro-1,3-butadiene and its conjugates
    • Lock EA, Ishmael J (1985) Effect of the organic acid transport inhibitor probenicid on renal cortical uptake and proximal tubular toxicity of hexachloro-1,3-butadiene and its conjugates. Toxicol Appl Pharmacol 8:32-42
    • (1985) Toxicol Appl Pharmacol , vol.8 , pp. 32-42
    • Lock, E.A.1    Ishmael, J.2
  • 20
    • 0024518795 scopus 로고
    • Cysteine conjugate β-lyase of rat kidney cytosol: Characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity
    • MacFarlane M, Foster JR, Gibson GG, King LJ, Lock EA (1989) Cysteine conjugate β-lyase of rat kidney cytosol: characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity. Toxicol Appl Pharmacol 98:185-197
    • (1989) Toxicol Appl Pharmacol , vol.98 , pp. 185-197
    • MacFarlane, M.1    Foster, J.R.2    Gibson, G.G.3    King, L.J.4    Lock, E.A.5
  • 21
    • 0028632775 scopus 로고
    • Cytosolic C-S lyase activity in human kidney samples: Relevance for the nephrotoxicity of halogenated alkenes in man
    • McCarthy RI, Lock EA, Hawksworth GM (1994) Cytosolic C-S lyase activity in human kidney samples: relevance for the nephrotoxicity of halogenated alkenes in man. Toxicol Ind Health 10:103-112
    • (1994) Toxicol Ind Health , vol.10 , pp. 103-112
    • McCarthy, R.I.1    Lock, E.A.2    Hawksworth, G.M.3
  • 22
    • 0028876211 scopus 로고
    • Isolation and characterisation of human proximal tubular cells derived from kidney cortical segments
    • McLaren J, Whiting P, Simpson J, Hawksworth G (1995) Isolation and characterisation of human proximal tubular cells derived from kidney cortical segments. Hum Exp Toxicol 14:916-922
    • (1995) Hum Exp Toxicol , vol.14 , pp. 916-922
    • McLaren, J.1    Whiting, P.2    Simpson, J.3    Hawksworth, G.4
  • 23
    • 0001489971 scopus 로고
    • The synthesis of nephrotoxic conjugates of glutathione and cysteine
    • Moore RB, Green T (1988) The synthesis of nephrotoxic conjugates of glutathione and cysteine. Toxicol Environ Chem 17:152-162
    • (1988) Toxicol Environ Chem , vol.17 , pp. 152-162
    • Moore, R.B.1    Green, T.2
  • 24
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 27
    • 0023031995 scopus 로고
    • The role of cysteine conjugate β-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells
    • Stevens JL, Hayden P, Taylor G (1986) The role of cysteine conjugate β-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells. J Biol Chem 261:3325-3332
    • (1986) J Biol Chem , vol.261 , pp. 3325-3332
    • Stevens, J.L.1    Hayden, P.2    Taylor, G.3
  • 28
    • 0024395315 scopus 로고
    • Quantitation of multiple pathways for the metabolism of nephrotoxic cysteine conjugates using selective inhibitors of L-alpha-hydroxy acid oxidase (L-amino acid oxidase) and cysteine conjugate beta-lyase
    • Stevens JL, Hatzinger PB, Hayden PJ (1989) Quantitation of multiple pathways for the metabolism of nephrotoxic cysteine conjugates using selective inhibitors of L-alpha-hydroxy acid oxidase (L-amino acid oxidase) and cysteine conjugate beta-lyase. Drug Metab Dispos 17:297-303
    • (1989) Drug Metab Dispos , vol.17 , pp. 297-303
    • Stevens, J.L.1    Hatzinger, P.B.2    Hayden, P.J.3
  • 29
    • 0021948684 scopus 로고
    • Isolation, culture and characterization of human renal tubular cells
    • Trifillis AL, Regec AL, Trump BF (1985) Isolation, culture and characterization of human renal tubular cells. J Urol 133:324-329
    • (1985) J Urol , vol.133 , pp. 324-329
    • Trifillis, A.L.1    Regec, A.L.2    Trump, B.F.3
  • 30
    • 0023740943 scopus 로고
    • High performance liquid chromatographic determination of α-keto acids in human serum and urine using 1,2-diamino-4,5-methylenedioxybenzene as a precolumn fluorescence derivatization reagent
    • Wang Z, Zaitsu K, Ohkura Y (1988) High performance liquid chromatographic determination of α-keto acids in human serum and urine using 1,2-diamino-4,5-methylenedioxybenzene as a precolumn fluorescence derivatization reagent. J Chromatogr 430:223-231
    • (1988) J Chromatogr , vol.430 , pp. 223-231
    • Wang, Z.1    Zaitsu, K.2    Ohkura, Y.3
  • 31
    • 0024425380 scopus 로고
    • In vitro and in vivo nephrotoxicity of the k and D isomers of S-(1,2-dichlorovinyl)-cysteine
    • Wolfgang GHI, Gandolfi AJ, Stevens JL, Brendel K (1989) In vitro and in vivo nephrotoxicity of the k and D isomers of S-(1,2-dichlorovinyl)-cysteine. Toxicology 58:33-42
    • (1989) Toxicology , vol.58 , pp. 33-42
    • Wolfgang, G.H.I.1    Gandolfi, A.J.2    Stevens, J.L.3    Brendel, K.4
  • 32
    • 0025284579 scopus 로고
    • Assessment of S-(1,2-dichlorovinyl)-L-cysteine induced toxic events in rabbit renal cortical slices. Biochemical and histological evaluation of uptake covalent binding and toxicity
    • Wolfgang GHI, Gandolfi AJ, Nagle RB, Brendel K, Stevens JL (1990) Assessment of S-(1,2-dichlorovinyl)-L-cysteine induced toxic events in rabbit renal cortical slices. Biochemical and histological evaluation of uptake covalent binding and toxicity. Chem Biol Interact 75:153-170
    • (1990) Chem Biol Interact , vol.75 , pp. 153-170
    • Wolfgang, G.H.I.1    Gandolfi, A.J.2    Nagle, R.B.3    Brendel, K.4    Stevens, J.L.5


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