-
1
-
-
0242290366
-
Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux
-
Bahkiya N., Bahn A., Burckhardt G., and Wolff N.A. Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux. Cell. Physiol. Biochem. 13 (2003) 249-256
-
(2003)
Cell. Physiol. Biochem.
, vol.13
, pp. 249-256
-
-
Bahkiya, N.1
Bahn, A.2
Burckhardt, G.3
Wolff, N.A.4
-
2
-
-
0035165579
-
Regulation of renal tubular secretion of organic compounds
-
Berkhin E.B., and Humphreys M.H. Regulation of renal tubular secretion of organic compounds. Kidney Int. 59 (2001) 17-30
-
(2001)
Kidney Int.
, vol.59
, pp. 17-30
-
-
Berkhin, E.B.1
Humphreys, M.H.2
-
3
-
-
0035354577
-
Molecular physiology of renal p-aminohippurate secretion
-
Burckhardt G., Bahn A., and Wolff N.A. Molecular physiology of renal p-aminohippurate secretion. News Physiol. Sci. 16 (2001) 114-118
-
(2001)
News Physiol. Sci.
, vol.16
, pp. 114-118
-
-
Burckhardt, G.1
Bahn, A.2
Wolff, N.A.3
-
4
-
-
0035039326
-
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney
-
Cha S.H., Sekine T., Fukushima J.-I., Kanai Y., Kobayashi Y., Goya T., and Endou H. Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol. Pharmacol. 59 (2001) 1277-1286
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1277-1286
-
-
Cha, S.H.1
Sekine, T.2
Fukushima, J.-I.3
Kanai, Y.4
Kobayashi, Y.5
Goya, T.6
Endou, H.7
-
5
-
-
0033975309
-
Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-l-cysteine in freshly isolated human proximal tubular cells
-
Cummings B.S., and Lash L.H. Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-l-cysteine in freshly isolated human proximal tubular cells. Toxicol. Sci. 53 (2000) 458-466
-
(2000)
Toxicol. Sci.
, vol.53
, pp. 458-466
-
-
Cummings, B.S.1
Lash, L.H.2
-
6
-
-
0034056796
-
Expression of glutathione-dependent enzymes and cytochrome P450s in freshly isolated and primary cultures of proximal tubular cells from human kidney
-
Cummings B.S., Lasker J.M., and Lash L.H. Expression of glutathione-dependent enzymes and cytochrome P450s in freshly isolated and primary cultures of proximal tubular cells from human kidney. J. Pharmacol. Exp. Ther. 293 (2000) 677-685
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 677-685
-
-
Cummings, B.S.1
Lasker, J.M.2
Lash, L.H.3
-
8
-
-
1242272736
-
Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties
-
Hagenbuch B., and Peier P.J. Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch. 447 (2004) 653-665
-
(2004)
Pflugers Arch.
, vol.447
, pp. 653-665
-
-
Hagenbuch, B.1
Peier, P.J.2
-
9
-
-
0016756374
-
The mitochondrial pyruvate carrier: kinetics and specificity for substrates and inhibitors
-
Halestrap A.P. The mitochondrial pyruvate carrier: kinetics and specificity for substrates and inhibitors. Biochem. J. 148 (1975) 85-96
-
(1975)
Biochem. J.
, vol.148
, pp. 85-96
-
-
Halestrap, A.P.1
-
10
-
-
0036175127
-
Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions
-
Hasegawa M., Kusuhara H., Sugiyama D., Ito K., Ueda S., Endou H., and Sugiyama Y. Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. J. Pharmacol. Exp. Ther. 300 (2002) 746-753
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 746-753
-
-
Hasegawa, M.1
Kusuhara, H.2
Sugiyama, D.3
Ito, K.4
Ueda, S.5
Endou, H.6
Sugiyama, Y.7
-
11
-
-
0033849976
-
Cellular and molecular aspects of drug transport in the kidney
-
Inui K.-I., Masuda S., and Saito H. Cellular and molecular aspects of drug transport in the kidney. Kidney Int. 58 (2000) 944-958
-
(2000)
Kidney Int.
, vol.58
, pp. 944-958
-
-
Inui, K.-I.1
Masuda, S.2
Saito, H.3
-
12
-
-
0036073213
-
Gender differences in the urinary excretion of organic anions in rats
-
Kato Y., Kuge K., Kusuhara H., Meier P.J., and Sugiyama Y. Gender differences in the urinary excretion of organic anions in rats. J. Pharmacol. Exp. Ther. 302 (2002) 483-489
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.302
, pp. 483-489
-
-
Kato, Y.1
Kuge, K.2
Kusuhara, H.3
Meier, P.J.4
Sugiyama, Y.5
-
13
-
-
33644781452
-
Implications of genetic polymorphisms in drug transporters for pharmacotherapy
-
Kerb R. Implications of genetic polymorphisms in drug transporters for pharmacotherapy. Cancer Lett. 234 (2006) 4-33
-
(2006)
Cancer Lett.
, vol.234
, pp. 4-33
-
-
Kerb, R.1
-
14
-
-
1242295185
-
The SLC22 drug transporter family
-
Koepsell H., and Endou H. The SLC22 drug transporter family. Pflugers Arch. 447 (2004) 666-676
-
(2004)
Pflugers Arch.
, vol.447
, pp. 666-676
-
-
Koepsell, H.1
Endou, H.2
-
15
-
-
17444419341
-
Role of glutathione transport processes in kidney function
-
Lash L.H. Role of glutathione transport processes in kidney function. Toxicol. Appl. Pharmacol. 204 (2005) 329-342
-
(2005)
Toxicol. Appl. Pharmacol.
, vol.204
, pp. 329-342
-
-
Lash, L.H.1
-
16
-
-
0035891527
-
Apoptosis, necrosis and cell proliferation induced by S-(1,2-dichlorovinyl)-l-cysteine in primary cultures of human proximal tubular cells
-
Lash L.H., Hueni S.E., and Putt D.A. Apoptosis, necrosis and cell proliferation induced by S-(1,2-dichlorovinyl)-l-cysteine in primary cultures of human proximal tubular cells. Toxicol. Appl. Pharmacol. 177 (2001) 1-16
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.177
, pp. 1-16
-
-
Lash, L.H.1
Hueni, S.E.2
Putt, D.A.3
-
17
-
-
0037112280
-
Cellular energetics and glutathione status in NRK-52E cells: toxicological implications
-
Lash L.H., Putt D.A., Hueni S.E., Cao W., Xu F., Kulidjian S.J., and Horwitz J.P. Cellular energetics and glutathione status in NRK-52E cells: toxicological implications. Biochem. Pharmacol. 64 (2002) 1533-1546
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 1533-1546
-
-
Lash, L.H.1
Putt, D.A.2
Hueni, S.E.3
Cao, W.4
Xu, F.5
Kulidjian, S.J.6
Horwitz, J.P.7
-
18
-
-
0038137502
-
Roles of necrosis, apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells
-
Lash L.H., Putt D.A., Hueni S.E., Krause R.J., and Elfarra A.A. Roles of necrosis, apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells. J. Pharmacol. Exp. Ther. 305 (2003) 1163-1172
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 1163-1172
-
-
Lash, L.H.1
Putt, D.A.2
Hueni, S.E.3
Krause, R.J.4
Elfarra, A.A.5
-
19
-
-
20444459421
-
Molecular markers of trichloroethylene-induced toxicity in human kidney cells
-
Lash L.H., Putt D.A., Hueni S.E., and Horwitz B.P. Molecular markers of trichloroethylene-induced toxicity in human kidney cells. Toxicol. Appl. Pharmacol. 206 (2005) 157-168
-
(2005)
Toxicol. Appl. Pharmacol.
, vol.206
, pp. 157-168
-
-
Lash, L.H.1
Putt, D.A.2
Hueni, S.E.3
Horwitz, B.P.4
-
20
-
-
0029416940
-
Susceptibility of primary cultures of proximal tubular and distal tubular cells from rat kidney to chemically induced toxicity
-
Lash L.H., Tokarz J.J., and Pegouske D.M. Susceptibility of primary cultures of proximal tubular and distal tubular cells from rat kidney to chemically induced toxicity. Toxicology 103 (1995) 85-103
-
(1995)
Toxicology
, vol.103
, pp. 85-103
-
-
Lash, L.H.1
Tokarz, J.J.2
Pegouske, D.M.3
-
21
-
-
1342344851
-
Transporters and renal drug elimination
-
Lee W., and Kim R.B. Transporters and renal drug elimination. Annu. Rev. Pharmacol. Toxicol. 44 (2004) 137-166
-
(2004)
Annu. Rev. Pharmacol. Toxicol.
, vol.44
, pp. 137-166
-
-
Lee, W.1
Kim, R.B.2
-
22
-
-
2942675119
-
Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition
-
Ljubojevic M., Herak-Kramberger C.M., Hagos Y., Bahn A., Endou H., Burckhardt G., and Sabolic I. Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition. Am. J. Physiol. 287 (2004) F124-F138
-
(2004)
Am. J. Physiol.
, vol.287
-
-
Ljubojevic, M.1
Herak-Kramberger, C.M.2
Hagos, Y.3
Bahn, A.4
Endou, H.5
Burckhardt, G.6
Sabolic, I.7
-
23
-
-
0032995116
-
Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C
-
Lu R., Chan B.S., and Schuster V.L. Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. Am. J. Physiol. 276 (1999) F295-F303
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Lu, R.1
Chan, B.S.2
Schuster, V.L.3
-
24
-
-
0036205460
-
Gene expression levels and immunolocalization of organic anion transporters in the human kidney
-
Motohashi H., Sakurai Y., Saito H., Masuda S., Urakami Y., Goto M., Fukatsu A., Ogawa O., and Inui K.-I. Gene expression levels and immunolocalization of organic anion transporters in the human kidney. J. Am. Soc. Nephrol. 13 (2002) 866-874
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 866-874
-
-
Motohashi, H.1
Sakurai, Y.2
Saito, H.3
Masuda, S.4
Urakami, Y.5
Goto, M.6
Fukatsu, A.7
Ogawa, O.8
Inui, K.-I.9
-
25
-
-
0033574034
-
Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)
-
Race J.E., Grassl S.M., Williams W.J., and Holtzman E.J. Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem. Biophys. Res. Commun. 255 (1999) 508-514
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.255
, pp. 508-514
-
-
Race, J.E.1
Grassl, S.M.2
Williams, W.J.3
Holtzman, E.J.4
-
26
-
-
31144464415
-
Human renal organic anion transporters: characteristics and contributions to drug and drug metabolite excretion
-
Robertson E.E., and Rankin G.O. Human renal organic anion transporters: characteristics and contributions to drug and drug metabolite excretion. Pharmacol. Ther. 109 (2006) 399-412
-
(2006)
Pharmacol. Ther.
, vol.109
, pp. 399-412
-
-
Robertson, E.E.1
Rankin, G.O.2
-
28
-
-
0029786681
-
Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney
-
Saito H., Masuda S., and Inui K.-I. Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney. J. Biol. Chem. 271 (1996) 20719-20725
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20719-20725
-
-
Saito, H.1
Masuda, S.2
Inui, K.-I.3
-
29
-
-
0019436833
-
A simple isolation method for basal-lateral plasma membranes from rat kidney cortex
-
Scalera V., Huang Y.-K., Hildman B., and Murer H. A simple isolation method for basal-lateral plasma membranes from rat kidney cortex. Membrane Biochem. 4 (1981) 49-61
-
(1981)
Membrane Biochem.
, vol.4
, pp. 49-61
-
-
Scalera, V.1
Huang, Y.-K.2
Hildman, B.3
Murer, H.4
-
30
-
-
0030855487
-
Expression cloning and characterization of a novel multispecific organic anion transporter
-
Sekine T., Watanabe N., Hosyamada M., Kanai Y., and Endou H. Expression cloning and characterization of a novel multispecific organic anion transporter. J. Biol. Chem. 272 (1997) 18526-18529
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18526-18529
-
-
Sekine, T.1
Watanabe, N.2
Hosyamada, M.3
Kanai, Y.4
Endou, H.5
-
31
-
-
0033938669
-
The multispecific organic anion transporter (OAT) family
-
Sekine T., Cha S.H., and Endou H. The multispecific organic anion transporter (OAT) family. Pflüg. Arch.: Eur. J. Physiol. 440 (2000) 337-350
-
(2000)
Pflüg. Arch.: Eur. J. Physiol.
, vol.440
, pp. 337-350
-
-
Sekine, T.1
Cha, S.H.2
Endou, H.3
-
32
-
-
0033387911
-
rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger
-
Sweet D.H., and Pritchard J.B. rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger. Am. J. Physiol. 277 (1999) F890-F898
-
(1999)
Am. J. Physiol.
, vol.277
-
-
Sweet, D.H.1
Pritchard, J.B.2
-
34
-
-
0033711928
-
Basolateral localization of organic cation transporter 2 in intact renal proximal tubules
-
Sweet D.H., Miller D.S., and Pritchard J.B. Basolateral localization of organic cation transporter 2 in intact renal proximal tubules. Am. J. Physiol. 279 (2000) F826-F834
-
(2000)
Am. J. Physiol.
, vol.279
-
-
Sweet, D.H.1
Miller, D.S.2
Pritchard, J.B.3
-
35
-
-
0030781076
-
Expression cloning and characterization of ROAT1: the basolateral organic anion transporter in rat kidney
-
Sweet D.H., Wolff N.A., and Pritchard J.B. Expression cloning and characterization of ROAT1: the basolateral organic anion transporter in rat kidney. J. Biol. Chem. 272 (1997) 30088-30095
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30088-30095
-
-
Sweet, D.H.1
Wolff, N.A.2
Pritchard, J.B.3
-
36
-
-
0006989879
-
Enzymatic isolation and serum-free culture of human renal cells
-
Jones G.E. (Ed), Humana Press, Inc, Totowa, NJ [Chapter 32]
-
Todd J.H., McMartin K.E., and Sens D.A. Enzymatic isolation and serum-free culture of human renal cells. In: Jones G.E. (Ed). Methods in Molecular Medicine: Human Cell Culture Protocols (1995), Humana Press, Inc, Totowa, NJ [Chapter 32]
-
(1995)
Methods in Molecular Medicine: Human Cell Culture Protocols
-
-
Todd, J.H.1
McMartin, K.E.2
Sens, D.A.3
-
38
-
-
0042844712
-
Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization
-
Wolff N.A., Thies K., Kuhnke N., Reid G., Friedrich B., Lang F., and Burckhardt G. Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. J. Am. Soc. Nephrol. 14 (2003) 1959-1968
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 1959-1968
-
-
Wolff, N.A.1
Thies, K.2
Kuhnke, N.3
Reid, G.4
Friedrich, B.5
Lang, F.6
Burckhardt, G.7
-
39
-
-
3042542425
-
Molecular and cellular physiology of renal organic cation and anion transport
-
Wright S.H., and Dantzler W.H. Molecular and cellular physiology of renal organic cation and anion transport. Physiol. Rev. 84 (2004) 987-1049
-
(2004)
Physiol. Rev.
, vol.84
, pp. 987-1049
-
-
Wright, S.H.1
Dantzler, W.H.2
|