Anti-inflammatory mechanisms of N-adamantyl-4-methylthiazol-2-amine in lipopolysaccharide-stimulated BV-2 microglial cells

International Immunopharmacology

Volumn 22, Issue 1, 2014, Pages 73-83

  Kim, Eun A ^a   Han, A Reum ^a   Choi, Jiyoung ^a   Ahn, Jee Yin ^b   Choi, Soo Young ^c   Cho, Sung Woo ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Hallym University   (South Korea)

Author keywords

Antioxidant; Microglia; Neurodegeneration; Neuroinflammation; Thiazole derivative

Indexed keywords

ANTIINFLAMMATORY AGENT; CATALASE; CD14 ANTIGEN; CYCLOOXYGENASE 2; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; KHG 26693; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; N ADAMANTYL 4 METHYLTHIAZOL 2 AMINE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; THIAZOLE DERIVATIVE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ADAMANTANE; ANTIOXIDANT; N-ADAMANTYL-4-METHYLTHIAZOL-2-AMINE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVATION; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME ACTIVITY; GROWTH INHIBITION; IN VITRO STUDY; INFLAMMATION; LIPID PEROXIDATION; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CELL MOTION; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE; NEURODEGENERATIVE DISEASES; SYNTHESIS;

ADAMANTANE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CELL LINE; CELL MOVEMENT; HYDROGEN PEROXIDE; INTERLEUKIN-1BETA; LIPID PEROXIDATION; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; MICROGLIA; NADPH OXIDASE; NEURODEGENERATIVE DISEASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; THIAZOLES; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84903738660     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.06.022     Document Type: Article

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