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Volumn 179, Issue 4, 1999, Pages 939-944

Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-γ

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENZYME INHIBITOR; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; PROTEIN KINASE; TUMOR NECROSIS FACTOR;

EID: 0032925361     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314659     Document Type: Article
Times cited : (321)

References (25)
  • 1
    • 0031570501 scopus 로고    scopus 로고
    • Mechanisms of nitric oxide-related antimicrobial activity
    • Fang F. Mechanisms of nitric oxide-related antimicrobial activity. J Clin Invest 1997;99:2818-25.
    • (1997) J Clin Invest , vol.99 , pp. 2818-2825
    • Fang, F.1
  • 2
    • 0027369020 scopus 로고
    • Evidence of increased nitric oxide production in patients with sepsis syndrome
    • Evans T, Carpenter A, Kinderman H, Cohen J. Evidence of increased nitric oxide production in patients with sepsis syndrome. Circ Shock 1993;41:77-81.
    • (1993) Circ Shock , vol.41 , pp. 77-81
    • Evans, T.1    Carpenter, A.2    Kinderman, H.3    Cohen, J.4
  • 3
    • 0030780758 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase: What difference does it make?
    • Nathan C. Inducible nitric oxide synthase: what difference does it make? J Clin Invest 1997;100:2417-23.
    • (1997) J Clin Invest , vol.100 , pp. 2417-2423
    • Nathan, C.1
  • 4
    • 0030711558 scopus 로고    scopus 로고
    • Nitric oxide synthases: Which, where, how, and why?
    • Michel T, Feron O. Nitric oxide synthases: which, where, how, and why? J Clin Invest 1997;100:2146-52.
    • (1997) J Clin Invest , vol.100 , pp. 2146-2152
    • Michel, T.1    Feron, O.2
  • 5
    • 0024405827 scopus 로고
    • The biology of cachectin/TNF a primary mediator of the host response
    • Beutler B. The biology of cachectin/TNF a primary mediator of the host response. Annu Rev Immunol 1989;7:625-55.
    • (1989) Annu Rev Immunol , vol.7 , pp. 625-655
    • Beutler, B.1
  • 6
    • 0029038728 scopus 로고
    • Plasma levels of cytokines in primary septic shock in humans: Correlation with disease severity
    • Gardlund B, Sjolin J, Nilsson A, Roll M, Wickerts CJ, Wretlind B. Plasma levels of cytokines in primary septic shock in humans: correlation with disease severity. J Infect Dis 1995;172:296-301.
    • (1995) J Infect Dis , vol.172 , pp. 296-301
    • Gardlund, B.1    Sjolin, J.2    Nilsson, A.3    Roll, M.4    Wickerts, C.J.5    Wretlind, B.6
  • 7
    • 0025823448 scopus 로고
    • ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
    • Boulton T, Nye SH, Robbins DJ, et al. ERKs: a family of protein-serine/ threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 1991;65:663-675.
    • (1991) Cell , vol.65 , pp. 663-675
    • Boulton, T.1    Nye, S.H.2    Robbins, D.J.3
  • 8
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994;372:739-46.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 9
    • 0028229012 scopus 로고
    • The stress activated protein kinase subfamily of c-Jun kinases
    • Kyriakis JM, Banjeree P, Nikolakaki E, et al. The stress activated protein kinase subfamily of c-Jun kinases. Nature 1994;369:156-60.
    • (1994) Nature , vol.369 , pp. 156-160
    • Kyriakis, J.M.1    Banjeree, P.2    Nikolakaki, E.3
  • 10
    • 0026659881 scopus 로고
    • Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages
    • Weinstein SL, Sanghera JS, Lemke K, DeFranco AL, Pelech SL. Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages. J Biol Chem 1992;267:14955-62.
    • (1992) J Biol Chem , vol.267 , pp. 14955-14962
    • Weinstein, S.L.1    Sanghera, J.S.2    Lemke, K.3    DeFranco, A.L.4    Pelech, S.L.5
  • 11
    • 0029836383 scopus 로고    scopus 로고
    • 2-terminal kinase mitogen-activated protein kinases by bacterial peptidoglycan
    • 2-terminal kinase mitogen-activated protein kinases by bacterial peptidoglycan. J Infect Dis 1996;174:777-85.
    • (1996) J Infect Dis , vol.174 , pp. 777-785
    • Dziarski, R.1    Jin, Y.P.2    Gupta, D.3
  • 12
    • 0029664650 scopus 로고    scopus 로고
    • Role of CSBP/p38/RK stress response kinase in LPS and cytokine signaling mechanisms
    • Lee JC, Young PR. Role of CSBP/p38/RK stress response kinase in LPS and cytokine signaling mechanisms. J Leukoc Biol 1996;59:152-7.
    • (1996) J Leukoc Biol , vol.59 , pp. 152-157
    • Lee, J.C.1    Young, P.R.2
  • 14
    • 0030881742 scopus 로고    scopus 로고
    • Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNFα) translation: Glucocorticoids inhibit TNFα translation by blocking JNK/SAPK
    • Swantek J, Cobb MH, Geppert T. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNFα) translation: glucocorticoids inhibit TNFα translation by blocking JNK/SAPK. Mol Cell Biol 1997;17:6274-82.
    • (1997) Mol Cell Biol , vol.17 , pp. 6274-6282
    • Swantek, J.1    Cobb, M.H.2    Geppert, T.3
  • 15
    • 0029788070 scopus 로고    scopus 로고
    • FcγR-dependent mitogen-activated protein kinase activation in leukocytes: A common signal transduction event necessary for expression of TNF-α and early activation genes
    • Trotta R, Kanakaraj P, Perussia B. FcγR-dependent mitogen-activated protein kinase activation in leukocytes: a common signal transduction event necessary for expression of TNF-α and early activation genes. J Exp Med 1996;184:1027-35.
    • (1996) J Exp Med , vol.184 , pp. 1027-1035
    • Trotta, R.1    Kanakaraj, P.2    Perussia, B.3
  • 16
    • 0032032424 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis-α gene expression in endotoxin-stimulated primary glial cultures
    • Bhat NR, Zhang P, Lee JC, Hogan EL. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis-α gene expression in endotoxin-stimulated primary glial cultures. J Neurosci 1998;18:1633-41.
    • (1998) J Neurosci , vol.18 , pp. 1633-1641
    • Bhat, N.R.1    Zhang, P.2    Lee, J.C.3    Hogan, E.L.4
  • 17
    • 0030712362 scopus 로고    scopus 로고
    • Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes
    • Da Silva J, Pierrat B, Mary JL, Lesslauer W. Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes. J Biol Chem 1997;272:28373-80.
    • (1997) J Biol Chem , vol.272 , pp. 28373-28380
    • Da Silva, J.1    Pierrat, B.2    Mary, J.L.3    Lesslauer, W.4
  • 18
    • 0031803059 scopus 로고    scopus 로고
    • SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes
    • Badger AM, Cook MN, Lark MW, et al. SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes. J Immunol 1998;161:467-73.
    • (1998) J Immunol , vol.161 , pp. 467-473
    • Badger, A.M.1    Cook, M.N.2    Lark, M.W.3
  • 19
    • 0032537557 scopus 로고    scopus 로고
    • Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW264 macrophages
    • Caivano M. Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW264 macrophages. FEBS Lett 1998;429:249-53.
    • (1998) FEBS Lett , vol.429 , pp. 249-253
    • Caivano, M.1
  • 20
    • 0029781529 scopus 로고    scopus 로고
    • Differential effects of tyrosine kinase inhibitors on tumor necrosis factor (TNF) and nitric oxide production by murine macrophages
    • Orlicek SL, Meals E. English BK. Differential effects of tyrosine kinase inhibitors on tumor necrosis factor (TNF) and nitric oxide production by murine macrophages. J Infect Dis 1996;174:638-42.
    • (1996) J Infect Dis , vol.174 , pp. 638-642
    • Orlicek, S.L.1    Meals, E.2    English, B.K.3
  • 21
    • 0032536875 scopus 로고    scopus 로고
    • Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock
    • Hierholzer C, Harbrecht B, Menezes JM, et al. Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J Exp Med 1998;187:917-28.
    • (1998) J Exp Med , vol.187 , pp. 917-928
    • Hierholzer, C.1    Harbrecht, B.2    Menezes, J.M.3
  • 22
    • 0030843135 scopus 로고    scopus 로고
    • Nitric oxide and septic shock
    • Thiemermann C. Nitric oxide and septic shock. Gen Pharmacol 1997;29:159-66.
    • (1997) Gen Pharmacol , vol.29 , pp. 159-166
    • Thiemermann, C.1
  • 23
    • 0031892252 scopus 로고    scopus 로고
    • Prolonged inhibition of nitric oxide synthesis in severe septic shock: A clinical study
    • Avontuur J, Nolthenius R, Bodegom J, Bruining H. Prolonged inhibition of nitric oxide synthesis in severe septic shock: a clinical study. Crit Care Med 1998;26:660-7.
    • (1998) Crit Care Med , vol.26 , pp. 660-667
    • Avontuur, J.1    Nolthenius, R.2    Bodegom, J.3    Bruining, H.4
  • 24
    • 0031985033 scopus 로고    scopus 로고
    • Non-selective versus selective inhibition of inducible nitric oxide synthase in experimental endoloxic shock
    • Liaudet L, Rosselet A, Schaller MD, Markert M, Perret C, Feihl F. Non-selective versus selective inhibition of inducible nitric oxide synthase in experimental endoloxic shock. J Infect Dis 1998;177:127-32.
    • (1998) J Infect Dis , vol.177 , pp. 127-132
    • Liaudet, L.1    Rosselet, A.2    Schaller, M.D.3    Markert, M.4    Perret, C.5    Feihl, F.6
  • 25
    • 0030426902 scopus 로고    scopus 로고
    • Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock, and immune function
    • Badger A, Bradbeer J, Votta B, Lee JC, Adams J, Griswold D. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock, and immune function. J Pharmacol Exp Ther 1996;279:1453-61.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 1453-1461
    • Badger, A.1    Bradbeer, J.2    Votta, B.3    Lee, J.C.4    Adams, J.5    Griswold, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.