메뉴 건너뛰기




Volumn 611, Issue 1-3, 2009, Pages 8-16

Curcumin mediates time and concentration dependent regulation of redox homeostasis leading to cytotoxicity in macrophage cells

Author keywords

radiation; Antioxidant genes; Curcumin; Reactive oxygen species; Thiols

Indexed keywords

ACETYLCYSTEINE; CURCUMIN; GLUTATHIONE; NONPROTEIN THIOL; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

EID: 67349134663     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.03.060     Document Type: Article
Times cited : (52)

References (51)
  • 1
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: preclinical and clinical studies
    • Aggarwal B.B., Kumar A., and Bharti A.C. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 23 (2003) 363-398
    • (2003) Anticancer Res. , vol.23 , pp. 363-398
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 4
    • 0037569694 scopus 로고    scopus 로고
    • Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
    • Balogun E., Hoque M., Gong P., Killeen E., Green C.J., Foresti R., Alam J., and Motterlini R. Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem. J. 371 (2003) 887-895
    • (2003) Biochem. J. , vol.371 , pp. 887-895
    • Balogun, E.1    Hoque, M.2    Gong, P.3    Killeen, E.4    Green, C.J.5    Foresti, R.6    Alam, J.7    Motterlini, R.8
  • 5
    • 0032815637 scopus 로고    scopus 로고
    • Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates
    • Bhaumik S., Anjum R., Rangaraj N., Pardhasaradhi B.V., and Khar A. Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates. FEBS Lett. 456 (1999) 311-314
    • (1999) FEBS Lett. , vol.456 , pp. 311-314
    • Bhaumik, S.1    Anjum, R.2    Rangaraj, N.3    Pardhasaradhi, B.V.4    Khar, A.5
  • 6
    • 13244289773 scopus 로고    scopus 로고
    • Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity
    • Biswas S.K., McClure D., Jimenez L.A., Megson I.L., and Rahman I. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxid. Redox Signal. 7 (2005) 32-41
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 32-41
    • Biswas, S.K.1    McClure, D.2    Jimenez, L.A.3    Megson, I.L.4    Rahman, I.5
  • 7
  • 8
    • 12744273421 scopus 로고    scopus 로고
    • Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells
    • Chen J., Wanming D., Zhang D., Liu Q., and Kang J. Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells. Pharmazie 60 (2005) 57-61
    • (2005) Pharmazie , vol.60 , pp. 57-61
    • Chen, J.1    Wanming, D.2    Zhang, D.3    Liu, Q.4    Kang, J.5
  • 9
    • 0036709597 scopus 로고    scopus 로고
    • Cellular glutathione and thiols metabolism
    • Dickinson D.A., and Forman H.J. Cellular glutathione and thiols metabolism. Biochem. Pharmacol. 64 (2002) 1019-1026
    • (2002) Biochem. Pharmacol. , vol.64 , pp. 1019-1026
    • Dickinson, D.A.1    Forman, H.J.2
  • 12
    • 21644477778 scopus 로고    scopus 로고
    • Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity
    • Fang J., Lu J., and Holmgren A. Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity. J. Biol. Chem. 280 (2005) 25284-25290
    • (2005) J. Biol. Chem. , vol.280 , pp. 25284-25290
    • Fang, J.1    Lu, J.2    Holmgren, A.3
  • 14
    • 40949089329 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis
    • Hail Jr. N. Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis. Free Radic. Biol. Med. 44 (2008) 1382-1393
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 1382-1393
    • Hail Jr., N.1
  • 16
    • 0031027060 scopus 로고    scopus 로고
    • Paraquat-induced formation of leukotriene B4 in rat lungs: modulation by N-acetylcysteine
    • Hoffer E.L., Shenker Y., Baum Y., and Tabak A. Paraquat-induced formation of leukotriene B4 in rat lungs: modulation by N-acetylcysteine. Free Radic. Biol. Med. 22 (1997) 567-572
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 567-572
    • Hoffer, E.L.1    Shenker, Y.2    Baum, Y.3    Tabak, A.4
  • 17
    • 0345074085 scopus 로고    scopus 로고
    • Dietary supplementation of curcumin enhances antioxidant and phase II metabolising enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity
    • Iqbal M., Sharma S.D., Okazaki Y., Fujisawa M., and Okada S. Dietary supplementation of curcumin enhances antioxidant and phase II metabolising enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity. Pharmacol. Toxicol. 92 (2003) 33-38
    • (2003) Pharmacol. Toxicol. , vol.92 , pp. 33-38
    • Iqbal, M.1    Sharma, S.D.2    Okazaki, Y.3    Fujisawa, M.4    Okada, S.5
  • 18
    • 27744609173 scopus 로고    scopus 로고
    • Curcumin sensitises tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
    • Jung E.M., Lim J.H., Lee T.J., Park J.W., Choi K.S., and Kwon T.K. Curcumin sensitises tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). Carcinogenesis 26 (2005) 1905-1913
    • (2005) Carcinogenesis , vol.26 , pp. 1905-1913
    • Jung, E.M.1    Lim, J.H.2    Lee, T.J.3    Park, J.W.4    Choi, K.S.5    Kwon, T.K.6
  • 19
    • 33748886920 scopus 로고    scopus 로고
    • Transport of liposomal and albumin loaded curcumin to living cells: an absorption and fluorescence spectroscopic study
    • Kunwar A., Barik A., Pandey R., and Priyadarsini K.I. Transport of liposomal and albumin loaded curcumin to living cells: an absorption and fluorescence spectroscopic study. Biochim. Biophys. Acta 1760 (2006) 1513-1520
    • (2006) Biochim. Biophys. Acta , vol.1760 , pp. 1513-1520
    • Kunwar, A.1    Barik, A.2    Pandey, R.3    Priyadarsini, K.I.4
  • 20
    • 35848929047 scopus 로고    scopus 로고
    • 3,3'-Diselenodipropionic acid, an efficient peroxyl radical scavenger and a GPx mimic, protects erythrocytes (RBCs) from AAPH-induced hemolysis
    • Kunwar A., Mishra B., Barik A., Kumbhare L.B., Pandey R., Jain V.K., and Priyadarsini K.I. 3,3'-Diselenodipropionic acid, an efficient peroxyl radical scavenger and a GPx mimic, protects erythrocytes (RBCs) from AAPH-induced hemolysis. Chem. Res. Toxicol. 20 (2007) 1482-1487
    • (2007) Chem. Res. Toxicol. , vol.20 , pp. 1482-1487
    • Kunwar, A.1    Mishra, B.2    Barik, A.3    Kumbhare, L.B.4    Pandey, R.5    Jain, V.K.6    Priyadarsini, K.I.7
  • 22
    • 15544362735 scopus 로고    scopus 로고
    • Snail and slug are major determinants of ovarian cancer invasiveness at the transcription level
    • Kurrey N.K., Amit K., and Bapat S.A. Snail and slug are major determinants of ovarian cancer invasiveness at the transcription level. Gynecol. Oncol. 97 (2005) 155-165
    • (2005) Gynecol. Oncol. , vol.97 , pp. 155-165
    • Kurrey, N.K.1    Amit, K.2    Bapat, S.A.3
  • 24
    • 38749097023 scopus 로고    scopus 로고
    • Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line
    • Li H., Berlo D., Shi T., Speit G., Knaapen Ad.M., Borm P.J.A., Albrecht C., and Schins R.P.F. Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line. Toxicol. Appl. Pharmacol. 227 (2008) 115-124
    • (2008) Toxicol. Appl. Pharmacol. , vol.227 , pp. 115-124
    • Li, H.1    Berlo, D.2    Shi, T.3    Speit, G.4    Knaapen, Ad.M.5    Borm, P.J.A.6    Albrecht, C.7    Schins, R.P.F.8
  • 27
    • 0034676493 scopus 로고    scopus 로고
    • Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology
    • Matés J.M. Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 153 (2000) 83-104
    • (2000) Toxicology , vol.153 , pp. 83-104
    • Matés, J.M.1
  • 28
    • 0035917844 scopus 로고    scopus 로고
    • Curcumin induces the mitochondrial permeability transition pore mediated by membrane protein thiol oxidation
    • Morin D., Barthelemy S., Zini R., Labidalle S., and Tillement J.P. Curcumin induces the mitochondrial permeability transition pore mediated by membrane protein thiol oxidation. FEBS lett. 495 (2001) 131-136
    • (2001) FEBS lett. , vol.495 , pp. 131-136
    • Morin, D.1    Barthelemy, S.2    Zini, R.3    Labidalle, S.4    Tillement, J.P.5
  • 29
    • 0034655773 scopus 로고    scopus 로고
    • Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress
    • Motterlini R., Foresti R., Bassi R., and Green C.J. Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radic. Biol. Med. 28 (2000) 1303-1312
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1303-1312
    • Motterlini, R.1    Foresti, R.2    Bassi, R.3    Green, C.J.4
  • 30
    • 33644865641 scopus 로고    scopus 로고
    • Delayed radioprotection by nuclear transcription factor κB-mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065
    • Murley J.S., Kataoka Y., Weydert C.Y., Oberley L.W., and Grdina D.J. Delayed radioprotection by nuclear transcription factor κB-mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065. Free Radic. Biol. Med. 40 (2006) 1004-1016
    • (2006) Free Radic. Biol. Med. , vol.40 , pp. 1004-1016
    • Murley, J.S.1    Kataoka, Y.2    Weydert, C.Y.3    Oberley, L.W.4    Grdina, D.J.5
  • 31
    • 0030798358 scopus 로고    scopus 로고
    • Free radical reactions of curcumin in membrane model
    • Priyadarsini K.I. Free radical reactions of curcumin in membrane model. Free Radic. Biol. Med. 23 (1997) 838-846
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 838-846
    • Priyadarsini, K.I.1
  • 32
    • 33750532308 scopus 로고    scopus 로고
    • Regulation of inflammation and redox signaling by dietary polyphenol
    • Rahman I., Biswas S.K., and Kirkham P.A. Regulation of inflammation and redox signaling by dietary polyphenol. Biochem. Pharmacol. 72 (2006) 1439-1452
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1439-1452
    • Rahman, I.1    Biswas, S.K.2    Kirkham, P.A.3
  • 33
    • 32344432720 scopus 로고    scopus 로고
    • Role of PKC δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes
    • Rushworth S.W., Ogborne R.M., Charalambos C.A., and O'Connell M.A. Role of PKC δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes. Biochem. Biophys. Res. Commun. 341 (2006) 1007-1016
    • (2006) Biochem. Biophys. Res. Commun. , vol.341 , pp. 1007-1016
    • Rushworth, S.W.1    Ogborne, R.M.2    Charalambos, C.A.3    O'Connell, M.A.4
  • 35
    • 34548058841 scopus 로고    scopus 로고
    • Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism
    • Sandur S.K., Pandey M.K., Sung B., Ahn K.S., Murakami A., Sethi G., Limtrakul P., Badmaev V., and Aggarwal B.B. Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. Carcinogenesis 28 (2007) 1765-1773
    • (2007) Carcinogenesis , vol.28 , pp. 1765-1773
    • Sandur, S.K.1    Pandey, M.K.2    Sung, B.3    Ahn, K.S.4    Murakami, A.5    Sethi, G.6    Limtrakul, P.7    Badmaev, V.8    Aggarwal, B.B.9
  • 36
    • 0035371184 scopus 로고    scopus 로고
    • Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
    • Schafer F.Q., and Buettner G.R. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic. Biol. Med. 30 (2001) 1191-1212
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 1191-1212
    • Schafer, F.Q.1    Buettner, G.R.2
  • 37
    • 0019961923 scopus 로고
    • Changes in glutathione, protein bound SH-groups concentrations in rat adrenals under acute and repeated stress
    • Sedlack J., and L'Hanus. Changes in glutathione, protein bound SH-groups concentrations in rat adrenals under acute and repeated stress. Endocrinol. Exp. 16 (1982) 103-109
    • (1982) Endocrinol. Exp. , vol.16 , pp. 103-109
    • Sedlack, J.1    L'Hanus2
  • 38
    • 0014428865 scopus 로고
    • Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent
    • Sedlak J., and Lindsay R. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal. Biochem. 25 (1968) 192-205
    • (1968) Anal. Biochem. , vol.25 , pp. 192-205
    • Sedlak, J.1    Lindsay, R.2
  • 39
    • 0017075410 scopus 로고
    • Antioxidant activity of curcumin and related compounds
    • Sharma O.P. Antioxidant activity of curcumin and related compounds. Biochem. Pharmacol. 25 (1976) 1811-1812
    • (1976) Biochem. Pharmacol. , vol.25 , pp. 1811-1812
    • Sharma, O.P.1
  • 42
    • 34548227773 scopus 로고    scopus 로고
    • From exotic spice to modern drug
    • Singh S. From exotic spice to modern drug. Cell 130 (2007) 765-768
    • (2007) Cell , vol.130 , pp. 765-768
    • Singh, S.1
  • 43
    • 33744490370 scopus 로고    scopus 로고
    • Biological effects of curcumin and its role in cancer chemoprevention and therapy
    • Singh S., and Khar A. Biological effects of curcumin and its role in cancer chemoprevention and therapy. Anticancer Agents Med. Chem. 6 (2006) 933-946
    • (2006) Anticancer Agents Med. Chem. , vol.6 , pp. 933-946
    • Singh, S.1    Khar, A.2
  • 45
    • 22144445327 scopus 로고    scopus 로고
    • The relationship between the anti-inflammatory effects of curcumin and cellular glutathione content in myelomonocytic cells
    • Strasser E.M., Wessner B., Manhart N., and Roth E. The relationship between the anti-inflammatory effects of curcumin and cellular glutathione content in myelomonocytic cells. Biochem. Pharmacol. 70 (2005) 552-559
    • (2005) Biochem. Pharmacol. , vol.70 , pp. 552-559
    • Strasser, E.M.1    Wessner, B.2    Manhart, N.3    Roth, E.4
  • 46
    • 56249106571 scopus 로고    scopus 로고
    • Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals
    • Surh Y.J., Kundu J.K., and Na H.K. Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals. Planta Med. 74 (2008) 1526-1539
    • (2008) Planta Med. , vol.74 , pp. 1526-1539
    • Surh, Y.J.1    Kundu, J.K.2    Na, H.K.3
  • 47
    • 4644364745 scopus 로고    scopus 로고
    • Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2
    • Syng-Ai C., Kumari A.L., and Khar A. Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2. Mol. Cancer Ther. 3 (2004) 1101-1108
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 1101-1108
    • Syng-Ai, C.1    Kumari, A.L.2    Khar, A.3
  • 48
    • 0012521621 scopus 로고
    • A method for viable cell count
    • Tolnai S. A method for viable cell count. Methods Cell Sci. 1 (1975) 37-38
    • (1975) Methods Cell Sci. , vol.1 , pp. 37-38
    • Tolnai, S.1
  • 50
    • 19544371395 scopus 로고    scopus 로고
    • β-Sitosterol modulates antioxidant enzyme response in RAW 264.7 macrophages
    • Vivancos M., and Moreno J.J. β-Sitosterol modulates antioxidant enzyme response in RAW 264.7 macrophages. Free Radic. Biol. Med. 39 (2005) 91-97
    • (2005) Free Radic. Biol. Med. , vol.39 , pp. 91-97
    • Vivancos, M.1    Moreno, J.J.2
  • 51
    • 29044433921 scopus 로고    scopus 로고
    • Inhibition of lipid peroxidation and protein oxidation in rat liver mitochondria by curcumin and its analogues
    • Wei Q.Y., Chen W.F., Zhou B., Yang L., and Liu Z.L. Inhibition of lipid peroxidation and protein oxidation in rat liver mitochondria by curcumin and its analogues. Biochim. Biophys. Acta 1760 (2006) 70-77
    • (2006) Biochim. Biophys. Acta , vol.1760 , pp. 70-77
    • Wei, Q.Y.1    Chen, W.F.2    Zhou, B.3    Yang, L.4    Liu, Z.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.