Effects of N-adamantyl-4-methylthiazol-2-amine on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats

European Journal of Pharmacology

Volumn 736, Issue , 2014, Pages 26-34

  Yang, Seung Ju ^a   Je Lee, Woo ^b   Kim, Eun A ^b   Dal Nam, Kee ^c   Hahn, Hoh Gyu ^c   Young Choi, Soo ^d   Cho, Sung Woo ^b  

^a Konyang University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

^d Hallym University   (South Korea)

Author keywords

Antioxidant; Diabetes; Inflammation; Oxidative stress; Thiazole derivative

Indexed keywords

ALPHA TOCOPHEROL; ANTIDIABETIC AGENT; ASCORBIC ACID; CATALASE; CHOLESTEROL; FRUCTOSE BISPHOSPHATASE; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUTATHIONE; GLYCOGEN PHOSPHORYLASE; GLYCOGEN SYNTHASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 1BETA; KHG 26693; N ADAMANTYL 4 METHYLTHIAZOL 2 AMINE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ADAMANTANE; ANTIINFLAMMATORY AGENT; ANTILIPEMIC AGENT; ANTIOXIDANT; GLUCOSE BLOOD LEVEL; MALONALDEHYDE; N-ADAMANTYL-4-METHYLTHIAZOL-2-AMINE; THIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HYPERGLYCEMIA; HYPERLIPIDEMIA; INSULIN BLOOD LEVEL; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRIACYLGLYCEROL BLOOD LEVEL; ANALOGS AND DERIVATIVES; ANALYSIS; ANIMAL; BLOOD; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; HYPERLIPIDEMIAS; LIPID METABOLISM; LIVER; METABOLISM; SPRAGUE DAWLEY RAT;

ADAMANTANE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; ASCORBIC ACID; BLOOD GLUCOSE; CATALASE; DIABETES MELLITUS, EXPERIMENTAL; GLUTATHIONE; HYPERGLYCEMIA; HYPERLIPIDEMIAS; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; INSULIN; INTERLEUKIN-1BETA; LIPID METABOLISM; LIPID PEROXIDATION; LIVER; MALE; MALONDIALDEHYDE; NF-KAPPA B; NITRIC OXIDE; OXIDATIVE STRESS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; THIAZOLES; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN E;

EID: 84900352195     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.04.031     Document Type: Article

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