Protosappanin A inhibits oxidative and nitrative stress via interfering the interaction of transmembrane protein CD14 with Toll-like receptor-4 in lipopolysaccharide-induced BV-2 microglia

International Immunopharmacology

Volumn 14, Issue 4, 2012, Pages 558-569

  Zeng, Ke Wu ^a   Zhao, Ming Bo ^a   Ma, Zhi Zhong ^a   Jiang, Yong ^a   Tu, Peng Fei ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

CD14; Nitrative stress; Oxidative stress; Protosappanin A; Toll like receptor 4

Indexed keywords

ANTIOXIDANT; CD14 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; PROTOSAPPANIN A; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BINDING; HUMAN; HUMAN CELL; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NITRATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, CD14; CELL LINE; COCULTURE TECHNIQUES; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; LIPOPOLYSACCHARIDES; MICROGLIA; MOLECULAR STRUCTURE; NADP; NEURONS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; NITROSATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENOLS; RATS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84867610600     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.09.004     Document Type: Article

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