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Volumn 46, Issue 7, 2013, Pages 370-375

Neuroprotective effects of the antioxidant action of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride against ischemic neuronal damage in the brain

Author keywords

2 cyclopropylimino 3 methyl 1,3 thiazoline hydrochloride; Antioxidative agent; Ischemia; Oxidative stress; Reactive oxygen species

Indexed keywords

2 CYCLOPROPYLIMINO 3 METHYL 1,3 THIAZOLINE HYDROCHLORIDE; 2-CYCLOPROPYLIMINO-3-METHYL-1,3-THIAZOLINE HYDROCHLORIDE; ANTIOXIDANT; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THIAZOLE DERIVATIVE;

EID: 84881445054     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2013.46.7.018     Document Type: Article
Times cited : (13)

References (39)
  • 1
    • 0031924622 scopus 로고    scopus 로고
    • Neuroprotective efficacy and mechanisms of novel pyrrolopyrimidine lipid peroxidation inhibitors in the gerbil forebrain ischemia model.
    • Oostveen, J. A., Dunn, E., Carter, D. B. and Hall, E. D. (1998) Neuroprotective efficacy and mechanisms of novel pyrrolopyrimidine lipid peroxidation inhibitors in the gerbil forebrain ischemia model. J. Cereb. Blood Flow Metab. 18, 539-547.
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 539-547
    • Oostveen, J.A.1    Dunn, E.2    Carter, D.B.3    Hall, E.D.4
  • 2
    • 0025314685 scopus 로고
    • Role of oxygen free radicals in carcinogenesis and brain ischemia.
    • Floyd, R. A. (1990) Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J. 4, 2587-2597.
    • (1990) FASEB J. , vol.4 , pp. 2587-2597
    • Floyd, R.A.1
  • 3
  • 4
    • 0035890197 scopus 로고    scopus 로고
    • Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons.
    • Frantseva, M. V., Carlen, P. L. and Perez Velazquez, J. L. (2001) Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons. Free Radic. Biol. Med. 31, 1216-1227.
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 1216-1227
    • Frantseva, M.V.1    Carlen, P.L.2    Perez Velazquez, J.L.3
  • 5
    • 0035890209 scopus 로고    scopus 로고
    • Free radical spin trap a-phenyl-N-tertbutyl-nitron inhibits caspase-3 activation and reduces brain damage following a severe forebrain ischemic injury.
    • Li, P. S., He, Q. P., Nakamura, L. and Csiszar, K. (2001) Free radical spin trap a-phenyl-N-tertbutyl-nitron inhibits caspase-3 activation and reduces brain damage following a severe forebrain ischemic injury. Free Radic. Biol. Med. 31, 1191-1197.
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 1191-1197
    • Li, P.S.1    He, Q.P.2    Nakamura, L.3    Csiszar, K.4
  • 9
    • 0027477946 scopus 로고
    • Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?
    • Beal, M. F., Hyman, B. T. and Koroshetz, W. (1993) Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases? Trends Neurosci. 16, 125-131.
    • (1993) Trends Neurosci. , vol.16 , pp. 125-131
    • Beal, M.F.1    Hyman, B.T.2    Koroshetz, W.3
  • 10
    • 34247158550 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases.
    • Trushina, E. and McMurray, C. T. (2007) Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases. Neuroscience 145, 1233-1248.
    • (2007) Neuroscience , vol.145 , pp. 1233-1248
    • Trushina, E.1    McMurray, C.T.2
  • 11
    • 22544462551 scopus 로고    scopus 로고
    • Antioxidant strategies in the treatment of stroke.
    • Margaill, I., Plotkine, M. and Lerouet, D. (2005) Antioxidant strategies in the treatment of stroke. Free Radic. Biol. Med. 39, 429-443.
    • (2005) Free Radic. Biol. Med. , vol.39 , pp. 429-443
    • Margaill, I.1    Plotkine, M.2    Lerouet, D.3
  • 12
    • 36448981390 scopus 로고    scopus 로고
    • Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology.
    • Schreibelt, G., Horssen, J. V., Rossum, S. V., Dijkstra, C. D., Drukarch, B. and Vries, H. E. (2007) Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology. Brain Res. Rev. 56, 322-330.
    • (2007) Brain Res. Rev. , vol.56 , pp. 322-330
    • Schreibelt, G.1    Horssen, J.V.2    Rossum, S.V.3    Dijkstra, C.D.4    Drukarch, B.5    Vries, H.E.6
  • 13
    • 34548299422 scopus 로고    scopus 로고
    • Protective effect of benzothiazole derivative KHG21834 on amyloid beta-induced neurotoxicity in PC12 cells and cortical and mesencephalic neurons.
    • Choi, M. M., Kim, E. A., Hahn, H. G., Nam, K. D., Yang, S. J., Choi, S. Y., Kim, T. U., Cho, S. W. and Huh, J. W. (2007) Protective effect of benzothiazole derivative KHG21834 on amyloid beta-induced neurotoxicity in PC12 cells and cortical and mesencephalic neurons. Toxicology 239, 156-166.
    • (2007) Toxicology , vol.239 , pp. 156-166
    • Choi, M.M.1    Kim, E.A.2    Hahn, H.G.3    Nam, K.D.4    Yang, S.J.5    Choi, S.Y.6    Kim, T.U.7    Cho, S.W.8    Huh, J.W.9
  • 14
    • 77956264216 scopus 로고    scopus 로고
    • Suppression of glutamate-induced excitotoxicity by 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride in rat glial cultures.
    • Kim, E. A., Hahn, H. G., Kim, K. S., Kim, T. U., Choi, S. Y. and Cho, S.-W. (2010) Suppression of glutamate-induced excitotoxicity by 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride in rat glial cultures. Cell. Mol. Neurobiol. 30, 807-815.
    • (2010) Cell. Mol. Neurobiol. , vol.30 , pp. 807-815
    • Kim, E.A.1    Hahn, H.G.2    Kim, K.S.3    Kim, T.U.4    Choi, S.Y.5    Cho, S.-W.6
  • 15
    • 77955836320 scopus 로고    scopus 로고
    • Attenuation of ß-amyloid-induced neuroinflammation by KHG21834 in vivo.
    • Kim, E. A., Hahn, H. G., Kim, T. U., Choi, S. Y. and Cho, S.-W. (2010) Attenuation of ß-amyloid-induced neuroinflammation by KHG21834 in vivo. BMB Rep. 43, 413-418.
    • (2010) BMB Rep. , vol.43 , pp. 413-418
    • Kim, E.A.1    Hahn, H.G.2    Kim, T.U.3    Choi, S.Y.4    Cho, S.-W.5
  • 16
    • 85027949963 scopus 로고    scopus 로고
    • Neuroprotective effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride against oxidative stress.
    • Kim, H., Son, H. J., Ha, S. C., Kim, E. A., Kim, T. U., Choi, S. Y., Ahn, J. Y. and Cho, S. W. (2011) Neuroprotective effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride against oxidative stress. Cell. Mol. Neurobiol. 31, 979-984.
    • (2011) Cell. Mol. Neurobiol. , vol.31 , pp. 979-984
    • Kim, H.1    Son, H.J.2    Ha, S.C.3    Kim, E.A.4    Kim, T.U.5    Choi, S.Y.6    Ahn, J.Y.7    Cho, S.W.8
  • 17
    • 0033787252 scopus 로고    scopus 로고
    • Riluzole inhibits the persistent sodium current in mammalian CNS neurons.
    • Urbani, A. and Belluzzi, O. (2000) Riluzole inhibits the persistent sodium current in mammalian CNS neurons. Eur. J. Neurosci. 12, 3567-3574.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 3567-3574
    • Urbani, A.1    Belluzzi, O.2
  • 19
    • 4043122453 scopus 로고    scopus 로고
    • Riluzole slows the progression of neuromuscular dysfunction in the wobbler mouse motor neuron disease.
    • Ishiyama, T., Okada, R., Nishibe, H., Mitsumoto, H. and Nakayama, C. (2004) Riluzole slows the progression of neuromuscular dysfunction in the wobbler mouse motor neuron disease. Brain Res. 1019, 226-236.
    • (2004) Brain Res. , vol.1019 , pp. 226-236
    • Ishiyama, T.1    Okada, R.2    Nishibe, H.3    Mitsumoto, H.4    Nakayama, C.5
  • 20
    • 33645999638 scopus 로고    scopus 로고
    • Anti-tumor drug candidate 2-(4-amino-3-methyl phenyl)-5-fluorobenzothiazole induces single-strand breaks and DNA-protein cross-links in sensitive MCF-7 breast cancer cells.
    • Brantley, E., Antony, S., Kohlhagen, G., Meng, L. H., Agama, K., Stinson, S. F., Sausville, E. A. and Pommier, Y. (2006) Anti-tumor drug candidate 2-(4-amino-3-methyl phenyl)-5-fluorobenzothiazole induces single-strand breaks and DNA-protein cross-links in sensitive MCF-7 breast cancer cells. Cancer Chemother. Pharmacol. 58, 62-72.
    • (2006) Cancer Chemother. Pharmacol. , vol.58 , pp. 62-72
    • Brantley, E.1    Antony, S.2    Kohlhagen, G.3    Meng, L.H.4    Agama, K.5    Stinson, S.F.6    Sausville, E.A.7    Pommier, Y.8
  • 21
    • 30444437324 scopus 로고    scopus 로고
    • Antitumor Benzothiazoles. 26.1 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines
    • Mortimer, C. G., Wells, G., Crochard, J. P., Stone, E. L., Bradshaw, T. D., Stevens, M. F. G. and Westwell, A. D. (2006) Antitumor Benzothiazoles. 26.1 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. J. Med. Chem. 49, 179-185.
    • (2006) J. Med. Chem. , vol.49 , pp. 179-185
    • Mortimer, C.G.1    Wells, G.2    Crochard, J.P.3    Stone, E.L.4    Bradshaw, T.D.5    Stevens, M.F.G.6    Westwell, A.D.7
  • 22
    • 33745142870 scopus 로고    scopus 로고
    • Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism.
    • Pietrancosta, N., Moumen, A., Dono, R., Lingor, P., Planchamp, V., Lamballe, F., Bahr, M., Kraus, J. L. and Maina, F. (2006) Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism. J. Med. Chem. 49, 3645-3652.
    • (2006) J. Med. Chem. , vol.49 , pp. 3645-3652
    • Pietrancosta, N.1    Moumen, A.2    Dono, R.3    Lingor, P.4    Planchamp, V.5    Lamballe, F.6    Bahr, M.7    Kraus, J.L.8    Maina, F.9
  • 23
    • 3042694681 scopus 로고    scopus 로고
    • AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties
    • Carboni, S., Hiver, A., Szyndralewiez, C., Gaillard, P., Gotteland, J. P. and Vitte, P. A. (2004) AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties. J. Pharmacol. Exp. Ther. 310, 25-32.
    • (2004) J. Pharmacol. Exp. Ther , vol.310 , pp. 25-32
    • Carboni, S.1    Hiver, A.2    Szyndralewiez, C.3    Gaillard, P.4    Gotteland, J.P.5    Vitte, P.A.6
  • 25
    • 0034889080 scopus 로고    scopus 로고
    • 4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia.
    • McKracken, E., Graham, D. I., Nilsen, M., Stewart, J., Nicoll, J. A. and Horsburgh, K. (2001) 4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia. Brain Pathol. 11, 414-421.
    • (2001) Brain Pathol. , vol.11 , pp. 414-421
    • McKracken, E.1    Graham, D.I.2    Nilsen, M.3    Stewart, J.4    Nicoll, J.A.5    Horsburgh, K.6
  • 28
    • 0029888311 scopus 로고    scopus 로고
    • Role of oxidants in ischemic brain damage.
    • Chan, P. H. (1996) Role of oxidants in ischemic brain damage. Stroke 27, 1124-1129.
    • (1996) Stroke , vol.27 , pp. 1124-1129
    • Chan, P.H.1
  • 29
    • 0030060186 scopus 로고    scopus 로고
    • Mitochondrial generation of reactive oxygen species after brain ischemia in the rat.
    • Piantadosi, C. A. and Zhang, J. (1996) Mitochondrial generation of reactive oxygen species after brain ischemia in the rat. Stroke 27, 327-331.
    • (1996) Stroke , vol.27 , pp. 327-331
    • Piantadosi, C.A.1    Zhang, J.2
  • 31
    • 0035913190 scopus 로고    scopus 로고
    • The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal.
    • Vieira, H. L., Belzacq, A. S. and Haouzi, D. (2001) The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal. Oncogene 20, 4305-4316.
    • (2001) Oncogene , vol.20 , pp. 4305-4316
    • Vieira, H.L.1    Belzacq, A.S.2    Haouzi, D.3
  • 32
    • 0034765766 scopus 로고    scopus 로고
    • Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils.
    • Candelario-Jalil, E., Mhadu, N. H., Al-Dalain, S. M., Martinez, G. and Leon, O. S. (2001) Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils. Neurosci. Res. 41, 233-241.
    • (2001) Neurosci. Res. , vol.41 , pp. 233-241
    • Candelario-Jalil, E.1    Mhadu, N.H.2    Al-Dalain, S.M.3    Martinez, G.4    Leon, O.S.5
  • 34
    • 34047136750 scopus 로고    scopus 로고
    • FeTPPS protects against global cerebral ischemic-reperfusion injury in gerbils.
    • Sharma, S. S., Dhar, A. and Kaundal, R. K. (2007) FeTPPS protects against global cerebral ischemic-reperfusion injury in gerbils. Pharmacol. Res. 55, 335-342.
    • (2007) Pharmacol. Res. , vol.55 , pp. 335-342
    • Sharma, S.S.1    Dhar, A.2    Kaundal, R.K.3
  • 35
    • 0034672943 scopus 로고    scopus 로고
    • Metabolism and functions of glutathione in brain.
    • Dringen, R. (2000) Metabolism and functions of glutathione in brain. Prog. Neurobiol. 62, 649-671.
    • (2000) Prog. Neurobiol. , vol.62 , pp. 649-671
    • Dringen, R.1
  • 38
    • 0021288821 scopus 로고
    • Assay of glutathione peroxidase.
    • Flohe, L. and Ginzler, W. A. (1984) Assay of glutathione peroxidase. Methods Enzymol. 105, 114-121.
    • (1984) Methods Enzymol. , vol.105 , pp. 114-121
    • Flohe, L.1    Ginzler, W.A.2
  • 39
    • 0021318441 scopus 로고
    • Catalase in vitro.
    • Aebi, H. (1984) Catalase in vitro. Methods Enzymol. 105, 121-126.
    • (1984) Methods Enzymol. , vol.105 , pp. 121-126
    • Aebi, H.1


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