2-aminothiazoles as therapeutic leads for prion diseases

Journal of Medicinal Chemistry

Volumn 54, Issue 4, 2011, Pages 1010-1021

  Gallardo Godoy, Alejandra ^a   Gever, Joel ^a   Fife, Kimberly L ^a   Silber, B Michael ^a,b   Prusiner, Stanley B ^a,b   Renslo, Adam R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(5 METHYLPYRIDIN 2 YL) [4 (3 PHENYLISOXAZOL 5 YL)THIAZOL 2 YL]AMINE; 2 AMINOTHIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BRAIN LEVEL; DRUG POTENCY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRION DISEASE; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIOLOGICAL ASSAY; BRAIN; CELL LINE, TUMOR; CELL SURVIVAL; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PRION DISEASES; PRPSC PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 79951821156     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm101250y     Document Type: Article

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