Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells

Journal of Neuroimmunology

Volumn 132, Issue 1-2, 2002, Pages 18-24

  Fiebich, Bernd L ^a   Lieb, Klaus ^a   Engels, Stefanie ^a   Heinrich, Michael ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

CNS; Feverfew (Tanacetum parthenium); Multiple sclerosis; Nitric oxide; Nitric oxide synthase; Sesquiterpene lactones

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PARTHENOLIDE;

ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME RELEASE; ENZYME SYNTHESIS; MICROGLIA; MOLECULAR MECHANICS; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

ANIMALS; CELLS, CULTURED; ENZYME ACTIVATION; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, WISTAR; SESQUITERPENES; TRANSCRIPTION FACTOR RELA;

EID: 0036848107     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00279-5     Document Type: Article

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