-
1
-
-
84858236079
-
Ensemble of G Protein-Coupled Receptor Active States
-
Park, P. S.-H. Ensemble of G Protein-Coupled Receptor Active States. Curr. Med. Chem., 2012, 19, 1146-1154.
-
(2012)
Curr. Med. Chem
, vol.19
, pp. 1146-1154
-
-
Park, P.S.-H.1
-
2
-
-
84864462348
-
Allosteric Modulators of Rhodopsin-like G Protein-Coupled Receptors: Opportunities in Drug Development
-
Muller, C. E.; Schiedel, A. C.; Baqi, Y. Allosteric Modulators of Rhodopsin-like G Protein-Coupled Receptors: Opportunities in Drug Development. Pharmacol. Ther., 2012, 135, 292-315.
-
(2012)
Pharmacol. Ther
, vol.135
, pp. 292-315
-
-
Muller, C.E.1
Schiedel, A.C.2
Baqi, Y.3
-
3
-
-
0038024615
-
The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
-
Fredriksson, R.; Lagerstrom, M. C.; Lundin, L.-G.; Schioth, H. B. The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints. Mol. Pharmacol., 2003, 63, 1256-72.
-
(2003)
Mol. Pharmacol
, vol.63
, pp. 1256-1272
-
-
Fredriksson, R.1
Lagerstrom, M.C.2
Lundin, L.-G.3
Schioth, H.B.4
-
4
-
-
33751547539
-
How Many Drug Targets Are There?
-
Overington, J. P.; Al-Lazikani, B.; Hopkins, A. L. How Many Drug Targets Are There? Nat. Rev. Drug Discov., 2006, 5, 993-996.
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 993-996
-
-
Overington, J.P.1
Al-Lazikani, B.2
Hopkins, A.L.3
-
5
-
-
77949370572
-
The Impact of GPCR Structures on Pharmacology and Structure-Based Drug Design
-
Congreve, M.; Marshall, F. The Impact of GPCR Structures on Pharmacology and Structure-Based Drug Design. Br. J. Pharmacol., 2010, 159, 986-996.
-
(2010)
Br. J. Pharmacol
, vol.159
, pp. 986-996
-
-
Congreve, M.1
Marshall, F.2
-
6
-
-
84891633786
-
Insights into the Structure of Class B GPCRs
-
Hollenstein, K.; de Graaf, C.; Bortolato, A.; Wang, M. W.; Marshall, F. H.; Stevens, R. C. Insights into the Structure of Class B GPCRs. Trends Pharmacol. Sci., 2014, 35, 12-22.
-
(2014)
Trends Pharmacol. Sci
, vol.35
, pp. 12-22
-
-
Hollenstein, K.1
de Graaf, C.2
Bortolato, A.3
Wang, M.W.4
Marshall, F.H.5
Stevens, R.C.6
-
7
-
-
84897580006
-
Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator
-
Wu, H.; Wang, C.; Gregory, K. J.; Han, G. W.; Cho, H. P.; Xia, Y.; Niswender, C. M.; Katritch, V.; Meiler, J.; Cherezov, V.; Conn, P. J.; Stevens, R. C. Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator. Science, 2014, 344, 58-64.
-
(2014)
Science
, vol.344
, pp. 58-64
-
-
Wu, H.1
Wang, C.2
Gregory, K.J.3
Han, G.W.4
Cho, H.P.5
Xia, Y.6
Niswender, C.M.7
Katritch, V.8
Meiler, J.9
Cherezov, V.10
Conn, P.J.11
Stevens, R.C.12
-
8
-
-
84867772612
-
Protein-Coupled Receptors: Signaling, Pharmacology, and Mechanisms of Activation
-
Paavola, K. J.; Hall, R. A. Adhesion G Protein-Coupled Receptors: Signaling, Pharmacology, and Mechanisms of Activation. Mol. Pharmacol., 2012, 82, 777-783.
-
(2012)
Mol. Pharmacol
, vol.82
, pp. 777-783
-
-
Paavola, K.J.1
Hall, R.A.2
Adhesion, G.3
-
9
-
-
3042798261
-
Molecular Mechanisms of Ligand Binding, Signaling, and Regulation within the Superfamily of G-Protein-Coupled Receptors: Molecular Modeling and Mutagenesis Approaches to Receptor Structure and Function
-
Kristiansen K. Molecular Mechanisms of Ligand Binding, Signaling, and Regulation within the Superfamily of G-Protein-Coupled Receptors: Molecular Modeling and Mutagenesis Approaches to Receptor Structure and Function. Pharmacol. Ther., 2004, 103, 21-80.
-
(2004)
Pharmacol. Ther
, vol.103
, pp. 21-80
-
-
Kristiansen, K.1
-
10
-
-
84878112106
-
Structure of the Human Smoothened Receptor Bound to an Antitumour Agent
-
Wang, C.; Wu, H.; Katritch, V.; Han, G. W.; Huang, X.-P.; Liu, W.; Siu, F. Y.; Roth, B. L.; Cherezov, V.; Stevens, R. C. Structure of the Human Smoothened Receptor Bound to an Antitumour Agent. Nature, 2013, 497, 338-343.
-
(2013)
Nature
, vol.497
, pp. 338-343
-
-
Wang, C.1
Wu, H.2
Katritch, V.3
Han, G.W.4
Huang, X.-P.5
Liu, W.6
Siu, F.Y.7
Roth, B.L.8
Cherezov, V.9
Stevens, R.C.10
-
11
-
-
84871286519
-
Restructuring G-Protein-Coupled Receptor Activation
-
Audet, M.; Bouvier, M. Restructuring G-Protein-Coupled Receptor Activation. Cell 2012, 151, 14-23.
-
(2012)
Cell
, vol.151
, pp. 14-23
-
-
Audet, M.1
Bouvier, M.2
-
12
-
-
84873685831
-
Molecular Signatures of G-Protein-Coupled Receptors
-
Venkatakrishnan, A.J.; Deupi, X.; Lebon, G.; Tate, C.G.; Schertler, G.F.; Babu, M. M. Molecular Signatures of G-Protein-Coupled Receptors. Nature, 2013, 494, 185-194.
-
(2013)
Nature
, vol.494
, pp. 185-194
-
-
Venkatakrishnan, A.J.1
Deupi, X.2
Lebon, G.3
Tate, C.G.4
Schertler, G.F.5
Babu, M.M.6
-
13
-
-
84881173408
-
Structure of Class B GPCR Corticotropin-Releasing Factor Receptor 1
-
Hollenstein, K.; Kean, J.; Bortolato, A.; Cheng, R. K. Y.; Dore, A. S.; Jazayeri, A.; Cooke, R. M.; Weir, M.; Marshall, F. H. Structure of Class B GPCR Corticotropin-Releasing Factor Receptor 1. Nature, 2013, 499, 438-443.
-
(2013)
Nature
, vol.499
, pp. 438-443
-
-
Hollenstein, K.1
Kean, J.2
Bortolato, A.3
Cheng, R.K.Y.4
Dore, A.S.5
Jazayeri, A.6
Cooke, R.M.7
Weir, M.8
Marshall, F.H.9
-
14
-
-
80051658642
-
Crystal Structure of the ß2 Adrenergic Receptor-Gs Protein Complex
-
Rasmussen, S.; De Vree, B.; Zou, Y. Crystal Structure of the ß2 Adrenergic Receptor-Gs Protein Complex. Nature, 2011, 477, 549-555.
-
(2011)
Nature
, vol.477
, pp. 549-555
-
-
Rasmussen, S.1
de Vree, B.2
Zou, Y.3
-
15
-
-
34250666273
-
Monomeric G Protein-Coupled Receptor Isolated in a High-Density Lipoprotein Particle Efficiently Activates Its G Protein
-
Whorton, M. R.; Bokoch, M. P.; Rasmussen, S. G. F.; Huang, B.; Zare, R. N.; Kobilka, B.; Sunahara, R. K. A Monomeric G Protein-Coupled Receptor Isolated in a High-Density Lipoprotein Particle Efficiently Activates Its G Protein. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 7682-7687.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 7682-7687
-
-
Whorton, M.R.1
Bokoch, M.P.2
Rasmussen, S.G.F.3
Huang, B.4
Zare, R.N.5
Kobilka, B.6
Sunahara, R.K.A.7
-
16
-
-
42949164679
-
Efficient Coupling of Transducin to Monomeric Rhodopsin in a Phospholipid Bilayer
-
Whorton, M. R.; Jastrzebska, B.; Park, P. S.-H.; Fotiadis, D.; Engel, A.; Palczewski, K.; Sunahara, R. K. Efficient Coupling of Transducin to Monomeric Rhodopsin in a Phospholipid Bilayer. J. Biol. Chem., 2008, 283, 4387-4394.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 4387-4394
-
-
Whorton, M.R.1
Jastrzebska, B.2
Park, P.S.-H.3
Fotiadis, D.4
Engel, A.5
Palczewski, K.6
Sunahara, R.K.7
-
17
-
-
70350381113
-
Purification and Functional Reconstitution of Monomeric Mu-Opioid Receptors: Allosteric Modulation of Agonist Binding by Gi2
-
Kuszak, A. J.; Pitchiaya, S.; Anand, J. P.; Mosberg, H. I.; Walter, N. G.; Sunahara, R. K. Purification and Functional Reconstitution of Monomeric Mu-Opioid Receptors: Allosteric Modulation of Agonist Binding by Gi2. J. Biol. Chem., 2009, 284, 26732-26741.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 26732-26741
-
-
Kuszak, A.J.1
Pitchiaya, S.2
Anand, J.P.3
Mosberg, H.I.4
Walter, N.G.5
Sunahara, R.K.6
-
18
-
-
78651390998
-
Monomeric Rhodopsin Is Sufficient for Normal Rhodopsin Kinase (GRK1) Phosphorylation and Arrestin-1 Binding
-
Bayburt, T. H.; Vishnivetskiy, S. A.; McLean, M. A.; Morizumi, T.; Huang, C.-C.; Tesmer, J. J. G.; Ernst, O. P.; Sligar, S. G.; Gurevich, V. V. Monomeric Rhodopsin Is Sufficient for Normal Rhodopsin Kinase (GRK1) Phosphorylation and Arrestin-1 Binding. J. Biol. Chem., 2011, 286, 1420-1428.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 1420-1428
-
-
Bayburt, T.H.1
Vishnivetskiy, S.A.2
McLean, M.A.3
Morizumi, T.4
Huang, C.-C.5
Tesmer, J.J.G.6
Ernst, O.P.7
Sligar, S.G.8
Gurevich, V.V.9
-
19
-
-
84856715703
-
High Constitutive Activity Is an Intrinsic Feature of Ghrelin Receptor Protein: A Study with a Functional Monomeric GHS-R1a Receptor Reconstituted in Lipid Discs
-
Damian, M.; Marie, J.; Leyris, J.-P.; Fehrentz, J.-A.; Verdie, P.; Martinez, J.; Baneres, J.-L.; Mary, S. High Constitutive Activity Is an Intrinsic Feature of Ghrelin Receptor Protein: A Study with a Functional Monomeric GHS-R1a Receptor Reconstituted in Lipid Discs. J. Biol. Chem., 2012, 287, 3630-3641.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 3630-3641
-
-
Damian, M.1
Marie, J.2
Leyris, J.-P.3
Fehrentz, J.-A.4
Verdie, P.5
Martinez, J.6
Baneres, J.-L.7
Mary, S.8
-
20
-
-
84876197291
-
Crystal Structure of Oligomeric ß1-Adrenergic G Protein-Coupled Receptors in Ligand-Free Basal State
-
Huang, J.; Chen, S.; Zhang, J. J.; Huang, X.-Y. Crystal Structure of Oligomeric ß1-Adrenergic G Protein-Coupled Receptors in Ligand-Free Basal State. Nat. Struct. Mol. Biol., 2013, 20, 419-425.
-
(2013)
Nat. Struct. Mol. Biol
, vol.20
, pp. 419-425
-
-
Huang, J.1
Chen, S.2
Zhang, J.J.3
Huang, X.-Y.4
-
21
-
-
72449193715
-
The Role of Dimerisation in the Cellular Trafficking of G-Protein-Coupled Receptors
-
Milligan, G. The Role of Dimerisation in the Cellular Trafficking of G-Protein-Coupled Receptors. Curr. Opin. Pharmacol., 2010, 10, 23-29.
-
(2010)
Curr. Opin. Pharmacol
, vol.10
, pp. 23-29
-
-
Milligan, G.1
-
22
-
-
69249158290
-
Allosteric Communication between Protomers of Dopamine Class A GPCR Dimers Modulates Activation
-
Han, Y.; Moreira, I. S.; Urizar, E.; Weinstein, H.; Javitch, J. A. Allosteric Communication between Protomers of Dopamine Class A GPCR Dimers Modulates Activation. Nat. Chem. Biol., 2009, 5, 688-695.
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 688-695
-
-
Han, Y.1
Moreira, I.S.2
Urizar, E.3
Weinstein, H.4
Javitch, J.A.5
-
23
-
-
79953177560
-
Protein Activation by Serotonin Type 4 Receptor Dimers: Evidence That Turning on Two Protomers is More Efficient
-
Pellissier, L. P.; Barthet, G.; Gaven, F.; Cassier, E.; Trinquet, E.; Pin, J.-P.; Marin, P.; Dumuis, A.; Bockaert, J.; Baneres, J.-L.; Claeysen, S. G Protein Activation by Serotonin Type 4 Receptor Dimers: Evidence That Turning on Two Protomers is More Efficient. J. Biol. Chem., 2011, 286, 9985-9997.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 9985-9997
-
-
Pellissier, L.P.1
Barthet, G.2
Gaven, F.3
Cassier, E.4
Trinquet, E.5
Pin, J.-P.6
Marin, P.7
Dumuis, A.8
Bockaert, J.9
Baneres, J.-L.10
Claeysen, S.G.11
-
24
-
-
84896692452
-
Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders
-
Moreno, J. L.; Holloway, T.; Gonzalez-Maeso, J. G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders. Prog. Mol. Biol. Transl. Sci., 2013, 117, 187-205.
-
(2013)
Prog. Mol. Biol. Transl. Sci
, vol.117
, pp. 187-205
-
-
Moreno, J.L.1
Holloway, T.2
Gonzalez-Maeso, J.G.3
-
25
-
-
70349109589
-
GPCR Homomers and Heteromers: A Better Choice as Targets for Drug Development than GPCR Monomers?
-
Casado, V.; Cortes, A.; Mallol, J.; Perez-Capote, K.; Ferre, S.; Lluis, C.; Franco, R.; Canela, E. I. GPCR Homomers and Heteromers: A Better Choice as Targets for Drug Development than GPCR Monomers? Pharmacol. Ther., 2009, 124, 248-257.
-
(2009)
Pharmacol. Ther
, vol.124
, pp. 248-257
-
-
Casado, V.1
Cortes, A.2
Mallol, J.3
Perez-Capote, K.4
Ferre, S.5
Lluis, C.6
Franco, R.7
Canela, E.I.8
-
26
-
-
80053511695
-
Oligomerization of G Protein-Coupled Receptors: Biochemical and Biophysical Methods
-
Kaczor, A. A.; Selent, J. Oligomerization of G Protein-Coupled Receptors: Biochemical and Biophysical Methods. Curr. Med. Chem., 2011, 18, 4606-4634.
-
(2011)
Curr. Med. Chem
, vol.18
, pp. 4606-4634
-
-
Kaczor, A.A.1
Selent, J.2
-
27
-
-
80053487319
-
Oligomerization of G Protein-Coupled Receptors: Computational Methods
-
Selent, J.; Kaczor, A. A. Oligomerization of G Protein-Coupled Receptors: Computational Methods. Curr. Med. Chem., 2011, 18, 4588-4605.
-
(2011)
Curr. Med. Chem
, vol.18
, pp. 4588-4605
-
-
Selent, J.1
Kaczor, A.A.2
-
28
-
-
1942468189
-
The G Protein-Coupled Receptor Rhodopsin in the Native Membrane
-
Fotiadis, D.; Liang, Y.; Filipek, S.; Saperstein, D. A.; Engel, A.; Palczewski, K. The G Protein-Coupled Receptor Rhodopsin in the Native Membrane. FEBS Lett., 2004, 564, 281-288.
-
(2004)
FEBS Lett
, vol.564
, pp. 281-288
-
-
Fotiadis, D.1
Liang, Y.2
Filipek, S.3
Saperstein, D.A.4
Engel, A.5
Palczewski, K.6
-
29
-
-
0041315589
-
C5a Receptor Oligomerization. I. Disulfide Trapping Reveals Oligomers and Potential Contact Surfaces in a G Protein-Coupled Receptor
-
Klco, J.M.; Lassere, T.B.; Baranski, T.J. C5a Receptor Oligomerization. I. Disulfide Trapping Reveals Oligomers and Potential Contact Surfaces in a G Protein-Coupled Receptor. J. Biol. Chem., 2003, 278, 35345-35353.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 35345-35353
-
-
Klco, J.M.1
Lassere, T.B.2
Baranski, T.J.3
-
30
-
-
51049112029
-
Dopamine D2 Receptors Form Higher Order Oligomers at Physiological Expression Levels
-
Guo, W.; Urizar, E.; Kralikova, M.; Mobarec, J. C.; Shi, L.; Filizola, M.; Javitch, J. A. Dopamine D2 Receptors Form Higher Order Oligomers at Physiological Expression Levels. EMBO J., 2008, 27, 2293-2304.
-
(2008)
EMBO J
, vol.27
, pp. 2293-2304
-
-
Guo, W.1
Urizar, E.2
Kralikova, M.3
Mobarec, J.C.4
Shi, L.5
Filizola, M.6
Javitch, J.A.7
-
31
-
-
3343026033
-
Oligomeric Potential of the M2 Muscarinic Cholinergic Receptor
-
Park, P. S.-H.; Wells, J. W. Oligomeric Potential of the M2 Muscarinic Cholinergic Receptor. J. Neurochem., 2004, 90, 537-548.
-
(2004)
J. Neurochem
, vol.90
, pp. 537-548
-
-
Park, P.S.-H.1
Wells, J.W.2
-
32
-
-
79958785452
-
The Oligomeric State Sets GABA(B) Receptor Signalling Efficacy
-
Comps-Agrar, L.; Kniazeff, J.; Norskov-Lauritsen, L.; Maurel, D.; Gassmann, M.; Gregor, N.; Prezeau, L.; Bettler, B.; Durroux, T.; Trinquet, E.; Pin, J. P. The Oligomeric State Sets GABA(B) Receptor Signalling Efficacy. EMBO J., 2011, 30, 2336-2349.
-
(2011)
EMBO J
, vol.30
, pp. 2336-2349
-
-
Comps-Agrar, L.1
Kniazeff, J.2
Norskov-Lauritsen, L.3
Maurel, D.4
Gassmann, M.5
Gregor, N.6
Prezeau, L.7
Bettler, B.8
Durroux, T.9
Trinquet, E.10
Pin, J.P.11
-
33
-
-
33751195311
-
Probing the Existence of G Protein-Coupled Receptor Dimers by Positive and Negative Ligand-Dependent Cooperative Binding
-
Albizu, L.; Balestre, M.-N.; Breton, C.; Pin, J.-P.; Manning, M.; Mouillac, B.; Barberis, C.; Durroux, T. Probing the Existence of G Protein-Coupled Receptor Dimers by Positive and Negative Ligand-Dependent Cooperative Binding. Mol. Pharmacol., 2006, 70, 1783-1791.
-
(2006)
Mol. Pharmacol
, vol.70
, pp. 1783-1791
-
-
Albizu, L.1
Balestre, M.-N.2
Breton, C.3
Pin, J.-P.4
Manning, M.5
Mouillac, B.6
Barberis, C.7
Durroux, T.8
-
34
-
-
84861854597
-
Heterotropic Cooperativity within and between Protomers of an Oligomeric M(2) Muscarinic Receptor
-
Shivnaraine, R. V.; Huang, X.-P.; Seidenberg, M.; Ellis, J.; Wells, J. W. Heterotropic Cooperativity within and between Protomers of an Oligomeric M(2) Muscarinic Receptor. Biochemistry (Mosc.), 2012, 51, 4518-4540.
-
(2012)
Biochemistry (Mosc.)
, vol.51
, pp. 4518-4540
-
-
Shivnaraine, R.V.1
Huang, X.-P.2
Seidenberg, M.3
Ellis, J.4
Wells, J.W.5
-
35
-
-
34547124343
-
Signaling through a G Protein-Coupled Receptor and Its Corresponding G Protein Follows a Stoichiometrically Limited Model
-
Philip, F.; Sengupta, P.; Scarlata, S. Signaling through a G Protein-Coupled Receptor and Its Corresponding G Protein Follows a Stoichiometrically Limited Model. J. Biol. Chem., 2007, 282, 19203-19216.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 19203-19216
-
-
Philip, F.1
Sengupta, P.2
Scarlata, S.3
-
36
-
-
61449236177
-
Analysis of Receptor Oligomerization by FRAP Microscopy
-
Dorsch, S.; Klotz, K.-N.; Engelhardt, S.; Lohse, M. J.; Bunemann, M. Analysis of Receptor Oligomerization by FRAP Microscopy. Nat. Methods, 2009, 6, 225-230.
-
(2009)
Nat. Methods
, vol.6
, pp. 225-230
-
-
Dorsch, S.1
Klotz, K.-N.2
Engelhardt, S.3
Lohse, M.J.4
Bunemann, M.5
-
37
-
-
44449096254
-
Cell-Surface Protein-Protein Interaction Analysis with Time-Resolved FRET and Snap-Tag Technologies: Application to GPCR Oligomerization
-
Maurel, D.; Comps-Agrar, L.; Brock, C.; Rives, M.-L.; Bourrier, E.; Ayoub, M. A.; Bazin, H.; Tinel, N.; Durroux, T.; Prezeau, L.; Trinquet, E.; Pin, J. P. Cell-Surface Protein-Protein Interaction Analysis with Time-Resolved FRET and Snap-Tag Technologies: Application to GPCR Oligomerization. Nat. Methods, 2008, 5, 561-567.
-
(2008)
Nat. Methods
, vol.5
, pp. 561-567
-
-
Maurel, D.1
Comps-Agrar, L.2
Brock, C.3
Rives, M.-L.4
Bourrier, E.5
Ayoub, M.A.6
Bazin, H.7
Tinel, N.8
Durroux, T.9
Prezeau, L.10
Trinquet, E.11
Pin, J.P.12
-
38
-
-
77955874300
-
Resolved FRET between GPCR Ligands Reveals Oligomers in Native Tissues
-
Albizu, L.; Cottet, M.; Kralikova, M.; Stoev, S.; Seyer, R.; Brabet, I.; Roux, T.; Bazin, H.; Bourrier, E.; Lamarque, L.; Breton, C.; Rives, M. L.; Newman, A.; Javitch, J.; Trinquet, E.; Manning, M.; Pin, J. P.; Mouillac, B.; Durroux, T. Resolved FRET between GPCR Ligands Reveals Oligomers in Native Tissues. Nat. Chem. Biol., 2010, 6, 587-594.
-
(2010)
Nat. Chem. Biol
, vol.6
, pp. 587-594
-
-
Albizu, L.1
Cottet, M.2
Kralikova, M.3
Stoev, S.4
Seyer, R.5
Brabet, I.6
Roux, T.7
Bazin, H.8
Bourrier, E.9
Lamarque, L.10
Breton, C.11
Rives, M.L.12
Newman, A.13
Javitch, J.14
Trinquet, E.15
Manning, M.16
Pin, J.P.17
Mouillac, B.18
Durroux, T.19
-
39
-
-
72449197630
-
Recent Advances in Bioluminescence Resonance Energy Transfer Technologies to Study GPCR Heteromerization
-
Ayoub, M.A.; Pfleger, K.D.G. Recent Advances in Bioluminescence Resonance Energy Transfer Technologies to Study GPCR Heteromerization. Curr. Opin. Pharmacol., 2010, 10, 44-52.
-
(2010)
Curr. Opin. Pharmacol
, vol.10
, pp. 44-52
-
-
Ayoub, M.A.1
Pfleger, K.D.G.2
-
40
-
-
78649740904
-
Combining Resonance Energy Transfer Methods Reveals a Complex between the alpha2AAdrenergic Receptor, Galphai1beta1gamma2, and GRK2
-
Breton, B.; Lagace, M.; Bouvier, M. Combining Resonance Energy Transfer Methods Reveals a Complex between the alpha2AAdrenergic Receptor, Galphai1beta1gamma2, and GRK2. FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol., 2010, 24, 4733-4743.
-
(2010)
FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol
, vol.24
, pp. 4733-4743
-
-
Breton, B.1
Lagace, M.2
Bouvier, M.3
-
41
-
-
84858203893
-
Fluorescence/ bioluminescence Resonance Energy Transfer Techniques to Study G-Protein-Coupled Receptor Activation and Signaling
-
Lohse, M.J.; Nuber, S.; Hoffmann, C. Fluorescence/ bioluminescence Resonance Energy Transfer Techniques to Study G-Protein-Coupled Receptor Activation and Signaling. Pharmacol. Rev., 2012, 64, 299-336.
-
(2012)
Pharmacol. Rev
, vol.64
, pp. 299-336
-
-
Lohse, M.J.1
Nuber, S.2
Hoffmann, C.3
-
42
-
-
84874363608
-
BRET Biosensors to Study GPCR Biology, Pharmacology, and Signal Transduction
-
Salahpour, A.; Espinoza, S.; Masri, B.; Lam, V.; Barak, L. S.; Gainetdinov, R. R. BRET Biosensors to Study GPCR Biology, Pharmacology, and Signal Transduction. Front. Endocrinol., 2012, 3, 105.
-
(2012)
Front. Endocrinol
, vol.3
, pp. 105
-
-
Salahpour, A.1
Espinoza, S.2
Masri, B.3
Lam, V.4
Barak, L.S.5
Gainetdinov, R.R.6
-
43
-
-
77955982118
-
Applications of Fluorescence and Bioluminescence Resonance Energy Transfer to Drug Discovery at G Protein Coupled Receptors
-
Alvarez-Curto, E.; Pediani, J. D.; Milligan, G. Applications of Fluorescence and Bioluminescence Resonance Energy Transfer to Drug Discovery at G Protein Coupled Receptors. Anal. Bioanal. Chem., 2010, 398, 167-180.
-
(2010)
Anal. Bioanal. Chem
, vol.398
, pp. 167-180
-
-
Alvarez-Curto, E.1
Pediani, J.D.2
Milligan, G.3
-
44
-
-
79953773529
-
The New Era of Bioluminescence Resonance Energy Transfer Technology
-
De, A. The New Era of Bioluminescence Resonance Energy Transfer Technology. Curr. Pharm. Biotechnol., 2011, 12, 558-568.
-
(2011)
Curr. Pharm. Biotechnol
, vol.12
, pp. 558-568
-
-
De, A.1
-
45
-
-
1442309077
-
Applications of Bioluminescence-and Fluorescence Resonance Energy Transfer to Drug Discovery at G Protein-Coupled Receptors
-
Milligan, G. Applications of Bioluminescence-and Fluorescence Resonance Energy Transfer to Drug Discovery at G Protein-Coupled Receptors. Eur. J. Pharm. Sci., 2004, 21, 397-405.
-
(2004)
Eur. J. Pharm. Sci
, vol.21
, pp. 397-405
-
-
Milligan, G.1
-
46
-
-
84981779372
-
Zwischenmolekulare Energiewanderung und Fluoreszenz
-
Forster, V. Zwischenmolekulare Energiewanderung und Fluoreszenz. Ann Phys. 1948, 6, 54-75.
-
(1948)
Ann Phys
, vol.6
, pp. 54-75
-
-
Forster, V.1
-
49
-
-
77953865084
-
-
Principles of Fluorescence Spectroscopy, third ed., Springer
-
Lakowicz, J. R. Principles of Fluorescence Spectroscopy, third ed., Springer, 2006.
-
(2006)
-
-
Lakowicz, J.R.1
-
50
-
-
41549124086
-
The BRET Technology and Its Application to Screening Assays
-
Bacart, J.; Corbel, C.; Jockers, R.; Bach, S.; Couturier, C. The BRET Technology and Its Application to Screening Assays. Biotechnol. J., 2008, 3, 311-324.
-
(2008)
Biotechnol. J
, vol.3
, pp. 311-324
-
-
Bacart, J.1
Corbel, C.2
Jockers, R.3
Bach, S.4
Couturier, C.5
-
51
-
-
0033524455
-
Bioluminescence Resonance Energy Transfer (BRET) System: Application to Interacting Circadian Clock Proteins
-
Xu, Y.; Piston, D. W.; Johnson, C. H. A Bioluminescence Resonance Energy Transfer (BRET) System: Application to Interacting Circadian Clock Proteins. Proc. Natl. Acad. Sci. U.S.A., 1999, 96, 151-156.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 151-156
-
-
Xu, Y.1
Piston, D.W.2
Johnson, C.H.A.3
-
52
-
-
0034724192
-
Detection of Beta 2-Adrenergic Receptor Dimerization in Living Cells Using Bioluminescence Resonance Energy Transfer (BRET)
-
Angers, S.; Salahpour, A.; Joly, E.; Hilairet, S.; Chelsky, D.; Dennis, M.; Bouvier, M. Detection of Beta 2-Adrenergic Receptor Dimerization in Living Cells Using Bioluminescence Resonance Energy Transfer (BRET). Proc. Natl. Acad. Sci. U.S.A., 2000, 97, 3684-3689.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 3684-3689
-
-
Angers, S.1
Salahpour, A.2
Joly, E.3
Hilairet, S.4
Chelsky, D.5
Dennis, M.6
Bouvier, M.7
-
53
-
-
84858977397
-
pHluorin2: An Enhanced, Ratiometric, pH-Sensitive Green Florescent Protein
-
Mahon, M. J. pHluorin2: An Enhanced, Ratiometric, pH-Sensitive Green Florescent Protein. Adv. Biosci. Biotechnol. Print, 2011, 2, 132-137.
-
(2011)
Adv. Biosci. Biotechnol. Print
, vol.2
, pp. 132-137
-
-
Mahon, M.J.1
-
54
-
-
0037160105
-
Quantitative Assessment of Beta 1-and Beta 2-Adrenergic Receptor Homo-and Heterodimerization by Bioluminescence Resonance Energy Transfer
-
Mercier, J.-F.; Salahpour, A.; Angers, S.; Breit, A.; Bouvier, M. Quantitative Assessment of Beta 1-and Beta 2-Adrenergic Receptor Homo-and Heterodimerization by Bioluminescence Resonance Energy Transfer. J. Biol. Chem., 2002, 277, 44925-44931.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 44925-44931
-
-
Mercier, J.-F.1
Salahpour, A.2
Angers, S.3
Breit, A.4
Bouvier, M.5
-
55
-
-
24144488192
-
High-Throughput Screening of G Protein-Coupled Receptor Antagonists Using a Bioluminescence Resonance Energy Transfer 1-Based Beta-arrestin2 Recruitment Assay
-
Hamdan, F. F.; Audet, M.; Garneau, P.; Pelletier, J.; Bouvier, M. High-Throughput Screening of G Protein-Coupled Receptor Antagonists Using a Bioluminescence Resonance Energy Transfer 1-Based Beta-arrestin2 Recruitment Assay. J. Biomol. Screen., 2005, 10, 463-475.
-
(2005)
J. Biomol. Screen
, vol.10
, pp. 463-475
-
-
Hamdan, F.F.1
Audet, M.2
Garneau, P.3
Pelletier, J.4
Bouvier, M.5
-
56
-
-
84874181001
-
Enhanced BRET Technology for the Monitoring of Agonist-Induced and Agonist-Independent Interactions between GPCRs and B-Arrestins
-
Kocan, M.; Dalrymple, M. B.; Seeber, R. M.; Feldman, B. J.; Pfleger, K. D. G. Enhanced BRET Technology for the Monitoring of Agonist-Induced and Agonist-Independent Interactions between GPCRs and B-Arrestins. Front. Endocrinol., 2010, 1(2), 1-9.
-
(2010)
Front. Endocrinol
, vol.1
, Issue.2
, pp. 1-9
-
-
Kocan, M.1
Dalrymple, M.B.2
Seeber, R.M.3
Feldman, B.J.4
Pfleger, K.D.G.5
-
57
-
-
84865565200
-
Effect of Enhanced Renilla Luciferase and Fluorescent Protein Variants on the Forster Distance of Bioluminescence Resonance Energy Transfer (BRET)
-
Dacres, H.; Michie, M.; Wang, J.; Pfleger, K. D. G.; Trowell, S. C. Effect of Enhanced Renilla Luciferase and Fluorescent Protein Variants on the Forster Distance of Bioluminescence Resonance Energy Transfer (BRET). Biochem. Biophys. Res. Commun., 2012, 425, 625-629.
-
(2012)
Biochem. Biophys. Res. Commun
, vol.425
, pp. 625-629
-
-
Dacres, H.1
Michie, M.2
Wang, J.3
Pfleger, K.D.G.4
Trowell, S.C.5
-
58
-
-
33748101201
-
Consensus Guided Mutagenesis of Renilla Luciferase Yields Enhanced Stability and Light Output
-
Loening, A. M.; Fenn, T. D.; Wu, A. M.; Gambhir, S. S. Consensus Guided Mutagenesis of Renilla Luciferase Yields Enhanced Stability and Light Output. Protein Eng. Des. Sel. PEDS, 2006, 19, 391-400.
-
(2006)
Protein Eng. Des. Sel. PEDS
, vol.19
, pp. 391-400
-
-
Loening, A.M.1
Fenn, T.D.2
Wu, A.M.3
Gambhir, S.S.4
-
59
-
-
75749088936
-
Experimental Determination of the Forster Distance for Two Commonly Used Bioluminescent Resonance Energy Transfer Pairs
-
Dacres, H.; Wang, J.; Dumancic, M.M.; Trowell, S.C. Experimental Determination of the Forster Distance for Two Commonly Used Bioluminescent Resonance Energy Transfer Pairs. Anal. Chem., 2010, 82, 432-435.
-
(2010)
Anal. Chem
, vol.82
, pp. 432-435
-
-
Dacres, H.1
Wang, J.2
Dumancic, M.M.3
Trowell, S.C.4
-
60
-
-
84859193459
-
Comparison of Enhanced Bioluminescence Energy Transfer Donors for Protease Biosensors
-
Dacres, H.; Michie, M.; Trowell, S. C. Comparison of Enhanced Bioluminescence Energy Transfer Donors for Protease Biosensors. Anal. Biochem., 2012, 424, 206-210.
-
(2012)
Anal. Biochem
, vol.424
, pp. 206-210
-
-
Dacres, H.1
Michie, M.2
Trowell, S.C.3
-
61
-
-
0036138908
-
A Variant of Yellow Fluorescent Protein with Fast and Efficient Maturation for Cell-Biological Applications
-
Nagai, T.; Ibata, K.; Park, E. S.; Kubota, M.; Mikoshiba, K.; Miyawaki, A. A Variant of Yellow Fluorescent Protein with Fast and Efficient Maturation for Cell-Biological Applications. Nat. Biotechnol., 2002, 20, 87-90.
-
(2002)
Nat. Biotechnol
, vol.20
, pp. 87-90
-
-
Nagai, T.1
Ibata, K.2
Park, E.S.3
Kubota, M.4
Mikoshiba, K.5
Miyawaki, A.6
-
62
-
-
53649086041
-
Demonstration of Improvements to the Bioluminescence Resonance Energy Transfer (BRET) Technology for the Monitoring of G Protein-Coupled Receptors in Live Cells
-
Kocan, M.; See, H. B.; Seeber, R. M.; Eidne, K. A.; Pfleger, K. D. G. Demonstration of Improvements to the Bioluminescence Resonance Energy Transfer (BRET) Technology for the Monitoring of G Protein-Coupled Receptors in Live Cells. J. Biomol. Screen., 2008, 13, 888-898.
-
(2008)
J. Biomol. Screen
, vol.13
, pp. 888-898
-
-
Kocan, M.1
See, H.B.2
Seeber, R.M.3
Eidne, K.A.4
Pfleger, K.D.G.5
-
63
-
-
64749087041
-
Agonist-Independent Interactions between Beta-Arrestins and Mutant Vasopressin Type II Receptors Associated with Nephrogenic Syndrome of Inappropriate Antidiuresis
-
Kocan, M.; See, H. B.; Sampaio, N. G.; Eidne, K. A.; Feldman, B. J.; Pfleger, K. D. G. Agonist-Independent Interactions between Beta-Arrestins and Mutant Vasopressin Type II Receptors Associated with Nephrogenic Syndrome of Inappropriate Antidiuresis. Mol. Endocrinol. Baltim. Md., 2009, 23, 559-571.
-
(2009)
Mol. Endocrinol. Baltim. Md
, vol.23
, pp. 559-571
-
-
Kocan, M.1
See, H.B.2
Sampaio, N.G.3
Eidne, K.A.4
Feldman, B.J.5
Pfleger, K.D.G.6
-
64
-
-
70350093721
-
Improved Donor/acceptor BRET Couples for Monitoring Beta-Arrestin Recruitment to G Protein-Coupled Receptors
-
Kamal, M.; Marquez, M.; Vauthier, V.; Leloire, A.; Froguel, P.; Jockers, R.; Couturier, C. Improved Donor/acceptor BRET Couples for Monitoring Beta-Arrestin Recruitment to G Protein-Coupled Receptors. Biotechnol. J., 2009, 4, 1337-1344.
-
(2009)
Biotechnol. J
, vol.4
, pp. 1337-1344
-
-
Kamal, M.1
Marquez, M.2
Vauthier, V.3
Leloire, A.4
Froguel, P.5
Jockers, R.6
Couturier, C.7
-
65
-
-
33747312516
-
Extended Bioluminescence Resonance Energy Transfer (eBRET) for Monitoring Prolonged Protein-Protein Interactions in Live Cells
-
Pfleger, K. D. G.; Dromey, J. R.; Dalrymple, M. B.; Lim, E. M. L.; Thomas, W. G.; Eidne, K. A. Extended Bioluminescence Resonance Energy Transfer (eBRET) for Monitoring Prolonged Protein-Protein Interactions in Live Cells. Cell. Signal., 2006, 18, 1664-1670.
-
(2006)
Cell. Signal
, vol.18
, pp. 1664-1670
-
-
Pfleger, K.D.G.1
Dromey, J.R.2
Dalrymple, M.B.3
Lim, E.M.L.4
Thomas, W.G.5
Eidne, K.A.6
-
66
-
-
84862744026
-
Nuclear Shuttling Precedes Dimerization in Mineralocorticoid Receptor Signaling
-
Grossmann, C.; Ruhs, S.; Langenbruch, L.; Mildenberger, S.; Stratz, N.; Schumann, K.; Gekle, M. Nuclear Shuttling Precedes Dimerization in Mineralocorticoid Receptor Signaling. Chem. Biol., 2012, 19, 742-751.
-
(2012)
Chem. Biol
, vol.19
, pp. 742-751
-
-
Grossmann, C.1
Ruhs, S.2
Langenbruch, L.3
Mildenberger, S.4
Stratz, N.5
Schumann, K.6
Gekle, M.7
-
67
-
-
34547619629
-
Luciferase-YFP Fusion Tag with Enhanced Emission for Single-Cell Luminescence Imaging
-
Hoshino, H.; Nakajima, Y.; Ohmiya, Y. Luciferase-YFP Fusion Tag with Enhanced Emission for Single-Cell Luminescence Imaging. Nat. Methods, 2007, 4, 637-639.
-
(2007)
Nat. Methods
, vol.4
, pp. 637-639
-
-
Hoshino, H.1
Nakajima, Y.2
Ohmiya, Y.3
-
68
-
-
68849115309
-
BRET3: A Red-Shifted Bioluminescence Resonance Energy Transfer (BRET)-Based Integrated Platform for Imaging Protein-Protein Interactions from Single Live Cells and Living Animals
-
De, A.; Ray, P.; Loening, A. M.; Gambhir, S. S. BRET3: A Red-Shifted Bioluminescence Resonance Energy Transfer (BRET)-Based Integrated Platform for Imaging Protein-Protein Interactions from Single Live Cells and Living Animals. FASEB J., 2009, 23, 2702-2709.
-
(2009)
FASEB J
, vol.23
, pp. 2702-2709
-
-
De, A.1
Ray, P.2
Loening, A.M.3
Gambhir, S.S.4
-
69
-
-
11144267737
-
Improved Monomeric Red, Orange and Yellow Fluorescent Proteins Derived from Discosoma Sp. Red Fluorescent Protein
-
Shaner, N.C.; Campbell, R.E.; Steinbach, P.A.; Giepmans, B.N.G.; Palmer, A.E.; Tsien, R.Y. Improved Monomeric Red, Orange and Yellow Fluorescent Proteins Derived from Discosoma Sp. Red Fluorescent Protein. Nat. Biotechnol., 2004, 22, 1567-1572.
-
(2004)
Nat. Biotechnol
, vol.22
, pp. 1567-1572
-
-
Shaner, N.C.1
Campbell, R.E.2
Steinbach, P.A.3
Giepmans, B.N.G.4
Palmer, A.E.5
Tsien, R.Y.6
-
70
-
-
79961083286
-
Bioluminescence Resonance Energy Transfer (BRET) Imaging of Protein-Protein Interactions within Deep Tissues of Living Subjects
-
Dragulescu-Andrasi, A.; Chan, C.T.; De, A.; Massoud, T.F.; Gambhir, S.S. Bioluminescence Resonance Energy Transfer (BRET) Imaging of Protein-Protein Interactions within Deep Tissues of Living Subjects. Proc. Natl. Acad. Sci. U.S.A., 2011, 108, 12060-12605.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 12060-12605
-
-
Dragulescu-Andrasi, A.1
Chan, C.T.2
De, A.3
Massoud, T.F.4
Gambhir, S.S.5
-
71
-
-
34547627492
-
Red-Shifted Renilla reniformis Luciferase Variants for Imaging in Living Subjects
-
Loening, A.M.; Wu, A.M.; Gambhir, S.S. Red-Shifted Renilla reniformis Luciferase Variants for Imaging in Living Subjects. Nat. Methods, 2007, 4, 641-643.
-
(2007)
Nat. Methods
, vol.4
, pp. 641-643
-
-
Loening, A.M.1
Wu, A.M.2
Gambhir, S.S.3
-
72
-
-
34548363677
-
Bright Far-Red Fluorescent Protein for Whole-Body Imaging
-
Shcherbo, D.; Merzlyak, E.M.; Chepurnykh, T.V.; Fradkov, A. F.; Ermakova, G.V.; Solovieva, E.A.; Lukyanov, K.A.; Bogdanova, E. A.; Zaraisky, A. G.; Lukyanov, S.; Chudakov, D. M. Bright Far-Red Fluorescent Protein for Whole-Body Imaging. Nat. Methods, 2007, 4, 741-746.
-
(2007)
Nat. Methods
, vol.4
, pp. 741-746
-
-
Shcherbo, D.1
Merzlyak, E.M.2
Chepurnykh, T.V.3
Fradkov, A.F.4
Ermakova, G.V.5
Solovieva, E.A.6
Lukyanov, K.A.7
Bogdanova, E.A.8
Zaraisky, A.G.9
Lukyanov, S.10
Chudakov, D.M.11
-
73
-
-
0031575902
-
The Use of Renilla luciferase, Oplophorus luciferase, and Apoaequorin as Bioluminescent Reporter Protein in the Presence of Coelenterazine Analogues as Substrate
-
Inouye, S.; Shimomura, O. The Use of Renilla luciferase, Oplophorus luciferase, and Apoaequorin as Bioluminescent Reporter Protein in the Presence of Coelenterazine Analogues as Substrate. Biochem. Biophys. Res. Commun., 1997, 233, 349-353.
-
(1997)
Biochem. Biophys. Res. Commun
, vol.233
, pp. 349-353
-
-
Inouye, S.1
Shimomura, O.2
-
74
-
-
74049120200
-
Red-Shifted Renilla luciferase for Transient Reporter-Gene Expression
-
Loening, A. M.; Dragulescu-Andrasi, A.; Gambhir, S. S. A Red-Shifted Renilla luciferase for Transient Reporter-Gene Expression. Nat. Methods, 2010, 7, 5-6.
-
(2010)
Nat. Methods
, vol.7
, pp. 5-6
-
-
Loening, A.M.1
Dragulescu-Andrasi, A.2
Gambhir, S.S.A.3
-
75
-
-
77955947906
-
Auto-Luminescent Genetically-Encoded Ratiometric Indicator for Real-Time Ca2+ Imaging at the Single Cell Level
-
Saito, K.; Hatsugai, N.; Horikawa, K.; Kobayashi, K.; Matsu-Ura, T.; Mikoshiba, K.; Nagai, T. Auto-Luminescent Genetically-Encoded Ratiometric Indicator for Real-Time Ca2+ Imaging at the Single Cell Level. PloS One, 2010, 5, e9935.
-
(2010)
PloS One
, vol.5
-
-
Saito, K.1
Hatsugai, N.2
Horikawa, K.3
Kobayashi, K.4
Matsu-Ura, T.5
Mikoshiba, K.6
Nagai, T.7
-
76
-
-
76549098526
-
Calcium Imaging in Single Neurons from Brain Slices Using Bioluminescent Reporters
-
Drobac, E.; Tricoire, L.; Chaffotte, A.-F.; Guiot, E.; Lambolez, B. Calcium Imaging in Single Neurons from Brain Slices Using Bioluminescent Reporters. J. Neurosci. Res., 2010, 88, 695-711.
-
(2010)
J. Neurosci. Res
, vol.88
, pp. 695-711
-
-
Drobac, E.1
Tricoire, L.2
Chaffotte, A.-F.3
Guiot, E.4
Lambolez, B.5
-
77
-
-
79955907733
-
Red Fluorescent Protein-Aequorin Fusions as Improved Bioluminescent Ca2+ Reporters in Single Cells and Mice
-
Bakayan, A.; Vaquero, C. F.; Picazo, F.; Llopis, J. Red Fluorescent Protein-Aequorin Fusions as Improved Bioluminescent Ca2+ Reporters in Single Cells and Mice. PloS One, 2011, 6, e19520.
-
(2011)
PloS One
, vol.e19520
, pp. 6
-
-
Bakayan, A.1
Vaquero, C.F.2
Picazo, F.3
Llopis, J.4
-
78
-
-
77949818688
-
Rapid and High-Sensitivity Cell-Based Assays of Protein-Protein Interactions Using Split Click Beetle Luciferase Complementation: An Approach to the Study of G-Protein-Coupled Receptors
-
Misawa, N.; Kafi, A. K. M.; Hattori, M.; Miura, K.; Masuda, K.; Ozawa, T. 2010. Rapid and High-Sensitivity Cell-Based Assays of Protein-Protein Interactions Using Split Click Beetle Luciferase Complementation: an Approach to the Study of G-Protein-Coupled Receptors. Anal. Chem., 2010, 82, 2552-2560.
-
(2010)
Anal. Chem
, vol.2010
, Issue.82
, pp. 2552-2560
-
-
Misawa, N.1
Kafi, A.K.M.2
Hattori, M.3
Miura, K.4
Masuda, K.5
Ozawa, T.6
-
79
-
-
84862103051
-
Visualization and Quantitative Analysis of G Protein-Coupled Receptor-ß-Arrestin Interaction in Single Cells and Specific Organs of Living Mice Using Split Luciferase Complementation
-
Takakura, H.; Hattori, M.; Takeuchi, M.; Ozawa, T. Visualization and Quantitative Analysis of G Protein-Coupled Receptor-ß-Arrestin Interaction in Single Cells and Specific Organs of Living Mice Using Split Luciferase Complementation. ACS Chem. Biol., 2012, 7, 901-910.
-
(2012)
ACS Chem. Biol
, vol.7
, pp. 901-910
-
-
Takakura, H.1
Hattori, M.2
Takeuchi, M.3
Ozawa, T.4
-
80
-
-
0037180571
-
Noninvasive Imaging of Protein-Protein Interactions in Living Subjects by Using Reporter Protein Complementation and Reconstitution Strategies
-
Paulmurugan, R.; Umezawa, Y.; Gambhir, S. S. Noninvasive Imaging of Protein-Protein Interactions in Living Subjects by Using Reporter Protein Complementation and Reconstitution Strategies. Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 15608-15613.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 15608-15613
-
-
Paulmurugan, R.1
Umezawa, Y.2
Gambhir, S.S.3
-
81
-
-
84862670921
-
Strategies for Membrane Interaction Proteomics: No Mass Spectrometry Required
-
Lam, M. H. Y.; Stagljar, I. Strategies for Membrane Interaction Proteomics: No Mass Spectrometry Required. Proteomics, 2012, 12, 1519-1526.
-
(2012)
Proteomics
, vol.12
, pp. 1519-1526
-
-
Lam, M.H.Y.1
Stagljar, I.2
-
82
-
-
80053574603
-
Imaging and Characterisation of the Surface of Live Cells
-
Klenerman, D.; Korchev, Y.E.; Davis, S.J. Imaging and Characterisation of the Surface of Live Cells. Curr. Opin. Chem. Biol., 2011, 15, 696-703.
-
(2011)
Curr. Opin. Chem. Biol
, vol.15
, pp. 696-703
-
-
Klenerman, D.1
Korchev, Y.E.2
Davis, S.J.3
-
83
-
-
66849093630
-
Evidence for Distinct Antagonist-Revealed Functional States of 5-hydroxytryptamine(2A) Receptor Homodimers
-
Brea, J.; Castro, M.; Giraldo, J.; Lopez-Gimenez, J. F.; Padin, J. F.; Quintian, F.; Cadavid, M. I.; Vilaro, M. T.; Mengod, G.; Berg, K. A.; Clarke, W. P.; Vilardaga, J. P.; Milligan, G.; Loza, M. I. Evidence for Distinct Antagonist-Revealed Functional States of 5-hydroxytryptamine(2A) Receptor Homodimers. Mol. Pharmacol., 2009, 75, 1380-1391.
-
(2009)
Mol. Pharmacol
, vol.75
, pp. 1380-1391
-
-
Brea, J.1
Castro, M.2
Giraldo, J.3
Lopez-Gimenez, J.F.4
Padin, J.F.5
Quintian, F.6
Cadavid, M.I.7
Vilaro, M.T.8
Mengod, G.9
Berg, K.A.10
Clarke, W.P.11
Vilardaga, J.P.12
Milligan, G.13
Loza, M.I.14
-
84
-
-
17444380779
-
Heterodimerization Is Required for the Formation of a Functional GABA(B) Receptor
-
White, J. H.; Wise, A.; Main, M. J.; Green, A.; Fraser, N. J.; Disney, G. H.; Barnes, A. A.; Emson, P.; Foord, S. M.; Marshall, F. H. Heterodimerization Is Required for the Formation of a Functional GABA(B) Receptor. Nature, 1998, 396, 679-682.
-
(1998)
Nature
, vol.396
, pp. 679-682
-
-
White, J.H.1
Wise, A.2
Main, M.J.3
Green, A.4
Fraser, N.J.5
Disney, G.H.6
Barnes, A.A.7
Emson, P.8
Foord, S.M.9
Marshall, F.H.10
-
85
-
-
0005169503
-
GABA(B) Receptors Function as a Heteromeric Assembly of the Subunits GABA(B)R1 and GABA(B)R2
-
Jones, K. A.; Borowsky, B.; Tamm, J. A.; Craig, D. A.; Durkin, M. M.; Dai, M.; Yao, W. J.; Johnson, M.; Gunwaldsen, C.; Huang, L. Y.; Tang, C.; Shen, Q.; Salon, J. A.; Morse, K.; Laz, T.; Smith, K. E.; Nagarathnam, D.; Noble, S. A.; Branchek, T. A.; Gerald, C. GABA(B) Receptors Function as a Heteromeric Assembly of the Subunits GABA(B)R1 and GABA(B)R2. Nature, 1998, 396, 674-679.
-
(1998)
Nature
, vol.396
, pp. 674-679
-
-
Jones, K.A.1
Borowsky, B.2
Tamm, J.A.3
Craig, D.A.4
Durkin, M.M.5
Dai, M.6
Yao, W.J.7
Johnson, M.8
Gunwaldsen, C.9
Huang, L.Y.10
Tang, C.11
Shen, Q.12
Salon, J.A.13
Morse, K.14
Laz, T.15
Smith, K.E.16
Nagarathnam, D.17
Noble, S.A.18
Branchek, T.A.19
Gerald, C.20
more..
-
86
-
-
84873155972
-
BRET and Time-Resolved FRET Strategy to Study GPCR Oligomerization: From Cell Lines toward Native Tissues
-
Cottet, M.; Faklaris, O.; Maurel, D.; Scholler, P.; Doumazane, E.; Trinquet, E.; Pin, J.-P.; Durroux, T. BRET and Time-Resolved FRET Strategy to Study GPCR Oligomerization: From Cell Lines toward Native Tissues. Front. Endocrinol., 2012, 3, 1-14.
-
(2012)
Front. Endocrinol
, vol.3
, pp. 1-14
-
-
Cottet, M.1
Faklaris, O.2
Maurel, D.3
Scholler, P.4
Doumazane, E.5
Trinquet, E.6
Pin, J.-P.7
Durroux, T.8
-
87
-
-
84873019413
-
Hetero-Oligomerization and Specificity Changes of G Protein-Coupled Purinergic Receptors: Novel Insight into Diversification of Signal Transduction
-
Suzuki, T.; Namba, K.; Mizuno, N.; Nakata, H. Hetero-Oligomerization and Specificity Changes of G Protein-Coupled Purinergic Receptors: Novel Insight into Diversification of Signal Transduction. Methods Enzymol., 2013, 521, 239-257.
-
(2013)
Methods Enzymol
, vol.521
, pp. 239-257
-
-
Suzuki, T.1
Namba, K.2
Mizuno, N.3
Nakata, H.4
-
88
-
-
3342965731
-
Preferential Formation of MT1/MT2 Melatonin Receptor Heterodimers with Distinct Ligand Interaction Properties Compared with MT2 Homodimers
-
Ayoub, M. A.; Levoye, A.; Delagrange, P.; Jockers, R. Preferential Formation of MT1/MT2 Melatonin Receptor Heterodimers with Distinct Ligand Interaction Properties Compared with MT2 Homodimers. Mol. Pharmacol., 2004, 66, 312-321.
-
(2004)
Mol. Pharmacol
, vol.66
, pp. 312-321
-
-
Ayoub, M.A.1
Levoye, A.2
Delagrange, P.3
Jockers, R.4
-
89
-
-
70350752293
-
Ligand-Regulated Oligomerization of beta(2)-Adrenoceptors in a Model Lipid Bilayer
-
Fung, J. J.; Deupi, X.; Pardo, L.; Yao, X. J.; Velez-Ruiz, G. A.; Devree, B. T.; Sunahara, R. K.; Kobilka, B. K. Ligand-Regulated Oligomerization of beta(2)-Adrenoceptors in a Model Lipid Bilayer. EMBO J., 2009, 28, 3315-3328.
-
(2009)
EMBO J
, vol.28
, pp. 3315-3328
-
-
Fung, J.J.1
Deupi, X.2
Pardo, L.3
Yao, X.J.4
Velez-Ruiz, G.A.5
Devree, B.T.6
Sunahara, R.K.7
Kobilka, B.K.8
-
90
-
-
34047107637
-
Two Transmembrane Cys Residues Are Involved in 5-HT4 Receptor Dimerization
-
Berthouze, M.; Rivail, L.; Lucas, A.; Ayoub, M. A.; Russo, O.; Sicsic, S.; Fischmeister, R.; Berque-Bestel, I.; Jockers, R.; Lezoualc'h, F. Two Transmembrane Cys Residues Are Involved in 5-HT4 Receptor Dimerization. Biochem.Biophys. Res. Commun., 2007, 356, 642-647.
-
(2007)
Biochem.Biophys. Res. Commun
, vol.356
, pp. 642-647
-
-
Berthouze, M.1
Rivail, L.2
Lucas, A.3
Ayoub, M.A.4
Russo, O.5
Sicsic, S.6
Fischmeister, R.7
Berque-Bestel, I.8
Jockers, R.9
Lezoualc'h, F.10
-
91
-
-
80051480604
-
Structural Basis of M3 Muscarinic Receptor Dimer/oligomer Formation
-
McMillin, S. M.; Heusel, M.; Liu, T.; Costanzi, S.; Wess, J. Structural Basis of M3 Muscarinic Receptor Dimer/oligomer Formation. J. Biol. Chem., 2011, 286, 28584-28598.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 28584-28598
-
-
McMillin, S.M.1
Heusel, M.2
Liu, T.3
Costanzi, S.4
Wess, J.5
-
92
-
-
84889006104
-
Novel Structural and Functional Insights into M3 Muscarinic Receptor Dimer/Oligomer Formation
-
Hu, J.; Hu, K.; Liu, T.; Stern, M. K.; Mistry, R.; Challiss, R. A. J.; Costanzi, S.; Wess, J. Novel Structural and Functional Insights into M3 Muscarinic Receptor Dimer/Oligomer Formation. J. Biol. Chem., 2013, 288, 34777-34790.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 34777-34790
-
-
Hu, J.1
Hu, K.2
Liu, T.3
Stern, M.K.4
Mistry, R.5
Challiss, R.A.J.6
Costanzi, S.7
Wess, J.8
-
93
-
-
28444493656
-
Crosstalk in G Protein-Coupled Receptors: Changes at the Transmembrane Homodimer Interface Determine Activation
-
Guo, W.; Shi, L.; Filizola, M.; Weinstein, H.; Javitch, J. A. Crosstalk in G Protein-Coupled Receptors: Changes at the Transmembrane Homodimer Interface Determine Activation. Proc. Natl. Acad. Sci. U.S.A., 2005, 102, 17495-17500.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 17495-17500
-
-
Guo, W.1
Shi, L.2
Filizola, M.3
Weinstein, H.4
Javitch, J.A.5
-
94
-
-
33845398829
-
Transmembrane Segment Peptides Can Disrupt Cholecystokinin Receptor Oligomerization without Affecting Receptor Function
-
Harikumar, K. G.; Dong, M.; Cheng, Z.; Pinon, D. I.; Lybrand, T. P.; Miller, L. J. Transmembrane Segment Peptides Can Disrupt Cholecystokinin Receptor Oligomerization without Affecting Receptor Function. Biochemistry (Mosc.), 2006, 45, 14706-14716.
-
(2006)
Biochemistry (Mosc.)
, vol.45
, pp. 14706-14716
-
-
Harikumar, K.G.1
Dong, M.2
Cheng, Z.3
Pinon, D.I.4
Lybrand, T.P.5
Miller, L.J.6
-
95
-
-
67650799169
-
Functional Importance of a Structurally Distinct Homodimeric Complex of the Family B G Protein-Coupled Secretin Receptor
-
Gao, F.; Harikumar, K. G.; Dong, M.; Lam, P. C.-H.; Sexton, P. M.; Christopoulos, A.; Bordner, A.; Abagyan, R.; Miller, L. J. Functional Importance of a Structurally Distinct Homodimeric Complex of the Family B G Protein-Coupled Secretin Receptor. Mol. Pharmacol., 2009, 76, 264-274.
-
(2009)
Mol. Pharmacol
, vol.76
, pp. 264-274
-
-
Gao, F.1
Harikumar, K.G.2
Dong, M.3
Lam, P.C.-H.4
Sexton, P.M.5
Christopoulos, A.6
Bordner, A.7
Abagyan, R.8
Miller, L.J.9
-
96
-
-
77955841797
-
Importance of Lipid-Exposed Residues in Transmembrane Segment Four for Family B Calcitonin Receptor Homo-Dimerization
-
Harikumar, K. G.; Ball, A. M.; Sexton, P. M.; Miller, L. J. Importance of Lipid-Exposed Residues in Transmembrane Segment Four for Family B Calcitonin Receptor Homo-Dimerization. Regul. Pept., 2010, 164, 113-119.
-
(2010)
Regul. Pept
, vol.164
, pp. 113-119
-
-
Harikumar, K.G.1
Ball, A.M.2
Sexton, P.M.3
Miller, L.J.4
-
97
-
-
58149097996
-
Pattern of Intra-Family Hetero-Oligomerization Involving the GProtein-Coupled Secretin Receptor
-
Harikumar, K. G.; Morfis, M. M.; Sexton, P. M.; Miller, L. J. Pattern of Intra-Family Hetero-Oligomerization Involving the GProtein-Coupled Secretin Receptor. J. Mol. Neurosci., 2008, 36, 279-285.
-
(2008)
J. Mol. Neurosci
, vol.36
, pp. 279-285
-
-
Harikumar, K.G.1
Morfis, M.M.2
Sexton, P.M.3
Miller, L.J.4
-
98
-
-
84871354260
-
The NTerminal HSDCIF Motif Is Required for Cell Surface Trafficking and Dimerization of Family B G Protein Coupled Receptor PAC1
-
Yu, R.; Guo, X.; Zhong, J.; Li, M.; Zeng, Z.; Zhang, H. The NTerminal HSDCIF Motif Is Required for Cell Surface Trafficking and Dimerization of Family B G Protein Coupled Receptor PAC1. PloS One, 2012, 7, e51811.
-
(2012)
PloS One
, vol.7
-
-
Yu, R.1
Guo, X.2
Zhong, J.3
Li, M.4
Zeng, Z.5
Zhang, H.6
-
99
-
-
84871353890
-
De. Receptor Oligomerization in Family B1 of G-Protein-Coupled Receptors: Focus on BRET Investigations and the Link between GPCR Oligomerization and Binding Cooperativity
-
Roed, S. N.; Orgaard, A.; Jorgensen, R.; Meyts, P. De. Receptor Oligomerization in Family B1 of G-Protein-Coupled Receptors: Focus on BRET Investigations and the Link between GPCR Oligomerization and Binding Cooperativity. Front. Endocrinol., 2012, 3, 1-13.
-
(2012)
Front. Endocrinol
, vol.3
, pp. 1-13
-
-
Roed, S.N.1
Orgaard, A.2
Jorgensen, R.3
Meyts, P.4
-
100
-
-
84874275263
-
Receptor Oligomerization: From Early Evidence to Current Understanding in Class B GPCRs
-
Ng, S.Y.L.; Lee, L.T.O.; Chow, B.K.C. Receptor Oligomerization: From Early Evidence to Current Understanding in Class B GPCRs. Front. Endocrinol., 2012, 3, 1-11.
-
(2012)
Front. Endocrinol
, vol.3
, pp. 1-11
-
-
Ng, S.Y.L.1
Lee, L.T.O.2
Chow, B.K.C.3
-
101
-
-
79951854466
-
Dimers and beyond: The Functional Puzzles of Class C GPCRs
-
Kniazeff, J.; Prezeau, L.; Rondard, P.; Pin, J.-P.; Goudet, C. Dimers and beyond: The Functional Puzzles of Class C GPCRs. Pharmacol. Ther., 2011, 130, 9-25.
-
(2011)
Pharmacol. Ther
, vol.130
, pp. 9-25
-
-
Kniazeff, J.1
Prezeau, L.2
Rondard, P.3
Pin, J.-P.4
Goudet, C.5
-
102
-
-
84874347669
-
Mathematical Models for Quantitative Assessment of Bioluminescence Resonance Energy Transfer: Application to Seven Transmembrane Receptors Oligomerization
-
Drinovec, L.; Kubale, V.; Nohr Larsen, J.; Vrecl, M. Mathematical Models for Quantitative Assessment of Bioluminescence Resonance Energy Transfer: Application to Seven Transmembrane Receptors Oligomerization. Front. Endocrinol., 2012, 3, 1-10.
-
(2012)
Front. Endocrinol
, vol.3
, pp. 1-10
-
-
Drinovec, L.1
Kubale, V.2
Nohr Larsen, J.3
Vrecl, M.4
-
103
-
-
61549138107
-
Constitutive Dimerization of the G-Protein Coupled Receptor, Neurotensin Receptor 1, Reconstituted into Phospholipid Bilayers
-
Harding, P. J.; Attrill, H.; Boehringer, J.; Ross, S.; Wadhams, G. H.; Smith, E.; Armitage, J. P.; Watts, A. Constitutive Dimerization of the G-Protein Coupled Receptor, Neurotensin Receptor 1, Reconstituted into Phospholipid Bilayers. Biophys. J., 2009, 96, 964-973.
-
(2009)
Biophys. J
, vol.96
, pp. 964-973
-
-
Harding, P.J.1
Attrill, H.2
Boehringer, J.3
Ross, S.4
Wadhams, G.H.5
Smith, E.6
Armitage, J.P.7
Watts, A.8
-
104
-
-
21344433619
-
Methods to Monitor the Quaternary Structure of G Protein-Coupled Receptors
-
Milligan, G.; Bouvier, M. Methods to Monitor the Quaternary Structure of G Protein-Coupled Receptors. FEBS J., 2005, 272, 2914-2925.
-
(2005)
FEBS J
, vol.272
, pp. 2914-2925
-
-
Milligan, G.1
Bouvier, M.2
-
105
-
-
33947362780
-
The alpha1b-Adrenoceptor Exists as a Higher-Order Oligomer: Effective Oligomerization is Required for Receptor Maturation, Surface Delivery, and Function
-
Lopez-Gimenez, J. F.; Canals, M.; Pediani, J. D.; Milligan, G. The alpha1b-Adrenoceptor Exists as a Higher-Order Oligomer: Effective Oligomerization is Required for Receptor Maturation, Surface Delivery, and Function. Mol. Pharmacol., 2007, 71, 1015-1029.
-
(2007)
Mol. Pharmacol
, vol.71
, pp. 1015-1029
-
-
Lopez-Gimenez, J.F.1
Canals, M.2
Pediani, J.D.3
Milligan, G.4
-
106
-
-
77952757509
-
Oligomeric Size of the m2 Muscarinic Receptor in Live Cells as Determined by Quantitative Fluorescence Resonance Energy Transfer
-
Pisterzi, L. F.; Jansma, D. B.; Georgiou, J.; Woodside, M. J.; Chou, J. T.-C.; Angers, S.; Raicu, V.; Wells, J. W. Oligomeric Size of the m2 Muscarinic Receptor in Live Cells as Determined by Quantitative Fluorescence Resonance Energy Transfer. J. Biol. Chem., 2010, 285, 16723-16738.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 16723-16738
-
-
Pisterzi, L.F.1
Jansma, D.B.2
Georgiou, J.3
Woodside, M.J.4
Chou, J.T.-C.5
Angers, S.6
Raicu, V.7
Wells, J.W.8
-
107
-
-
84877737677
-
The Muscarinic M3 Acetylcholine Receptor Exists as Two Differently Sized Complexes at the Plasma Membrane
-
Patowary, S.; Alvarez-Curto, E.; Xu, T.-R.; Holz, J. D.; Oliver, J. A.; Milligan, G.; Raicu, V. The Muscarinic M3 Acetylcholine Receptor Exists as Two Differently Sized Complexes at the Plasma Membrane. Biochem. J., 2013, 452, 303-312.
-
(2013)
Biochem. J
, vol.452
, pp. 303-312
-
-
Patowary, S.1
Alvarez-Curto, E.2
Xu, T.-R.3
Holz, J.D.4
Oliver, J.A.5
Milligan, G.6
Raicu, V.7
-
108
-
-
84865228987
-
Computational and Experimental Analysis of the Transmembrane Domain 4/5 Dimerization Interface of the Serotonin 5-HT(1A) Receptor
-
Gorinski, N.; Kowalsman, N.; Renner, U.; Wirth, A.; Reinartz, M. T.; Seifert, R.; Zeug, A.; Ponimaskin, E.; Niv, M. Y. Computational and Experimental Analysis of the Transmembrane Domain 4/5 Dimerization Interface of the Serotonin 5-HT(1A) Receptor. Mol. Pharmacol., 2012, 82, 448-463.
-
(2012)
Mol. Pharmacol
, vol.82
, pp. 448-463
-
-
Gorinski, N.1
Kowalsman, N.2
Renner, U.3
Wirth, A.4
Reinartz, M.T.5
Seifert, R.6
Zeug, A.7
Ponimaskin, E.8
Niv, M.Y.9
-
109
-
-
84872195772
-
Single-Molecule Analysis of Fluorescently Labeled G-Protein-Coupled Receptors Reveals Complexes with Distinct Dynamics and Organization
-
Calebiro, D.; Rieken, F.; Wagner, J.; Sungkaworn, T.; Zabel, U.; Borzi, A.; Cocucci, E.; Zurn, A.; Lohse, M. J. Single-Molecule Analysis of Fluorescently Labeled G-Protein-Coupled Receptors Reveals Complexes with Distinct Dynamics and Organization. Proc. Natl. Acad. Sci. U.S.A., 2013, 110, 743-748.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 743-748
-
-
Calebiro, D.1
Rieken, F.2
Wagner, J.3
Sungkaworn, T.4
Zabel, U.5
Borzi, A.6
Cocucci, E.7
Zurn, A.8
Lohse, M.J.9
-
110
-
-
80054730129
-
Using Quantitative BRET to Assess G Protein-Coupled Receptor Homo-and Heterodimerization
-
Achour, L.; Kamal, M.; Jockers, R.; Marullo, S. Using Quantitative BRET to Assess G Protein-Coupled Receptor Homo-and Heterodimerization. Methods Mol. Biol. Clifton N.J., 2011, 756, 183-200.
-
(2011)
Methods Mol. Biol. Clifton N.J
, vol.756
, pp. 183-200
-
-
Achour, L.1
Kamal, M.2
Jockers, R.3
Marullo, S.4
-
111
-
-
84875430188
-
Stoichiometric Analysis of Oligomerization of Membrane Proteins on Living Cells Using Coiled-Coil Labeling and Spectral Imaging
-
Kawano, K.; Yano, Y.; Omae, K.; Matsuzaki, S.; Matsuzaki, K. Stoichiometric Analysis of Oligomerization of Membrane Proteins on Living Cells Using Coiled-Coil Labeling and Spectral Imaging. Anal. Chem., 2013, 85, 3454-3461.
-
(2013)
Anal. Chem
, vol.85
, pp. 3454-3461
-
-
Kawano, K.1
Yano, Y.2
Omae, K.3
Matsuzaki, S.4
Matsuzaki, K.5
-
112
-
-
3242754218
-
Specific Labeling of Cell Surface Proteins with Chemically Diverse Compounds
-
George, N.; Pick, H.; Vogel, H.; Johnsson, N.; Johnsson, K. Specific Labeling of Cell Surface Proteins with Chemically Diverse Compounds. J. Am. Chem. Soc., 2004, 126, 8896-8897.
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 8896-8897
-
-
George, N.1
Pick, H.2
Vogel, H.3
Johnsson, N.4
Johnsson, K.5
-
113
-
-
77955058619
-
Lighting up Multiprotein Complexes: Lessons from GPCR Oligomerization
-
Ciruela, F.; Vilardaga, J.-P.; Fernandez-Duenas, V. Lighting up Multiprotein Complexes: Lessons from GPCR Oligomerization. Trends Biotechnol., 2010, 28, 407-415.
-
(2010)
Trends Biotechnol
, vol.28
, pp. 407-415
-
-
Ciruela, F.1
Vilardaga, J.-P.2
Fernandez-Duenas, V.3
-
114
-
-
18744376919
-
Real-Time Monitoring of Receptor and G-Protein Interactions in Living Cells
-
Gales, C.; Rebois, R. V.; Hogue, M.; Trieu, P.; Breit, A.; Hebert, T. E.; Bouvier, M. Real-Time Monitoring of Receptor and G-Protein Interactions in Living Cells. Nat. Methods, 2005, 2, 177-184.
-
(2005)
Nat. Methods
, vol.2
, pp. 177-184
-
-
Gales, C.1
Rebois, R.V.2
Hogue, M.3
Trieu, P.4
Breit, A.5
Hebert, T.E.6
Bouvier, M.7
-
115
-
-
84856414025
-
Protein Activation: Applications to Biased Ligands
-
Denis, C.; Sauliere, A.; Galandrin, S.; Senard, J.-M.; Gales, C. Probing Heterotrimeric G Protein Activation: Applications to Biased Ligands. Curr. Pharm. Des., 2012, 18, 128-144.
-
(2012)
Curr. Pharm. Des
, vol.18
, pp. 128-144
-
-
Denis, C.1
Sauliere, A.2
Galandrin, S.3
Senard, J.-M.4
Gales, C.5
Probing Heterotrimeric, G.6
-
116
-
-
33748355624
-
Probing the Activation-Promoted Structural Rearrangements in Preassembled Receptor-G Protein Complexes
-
Gales, C.; Durm, J. J. J. Van; Schaak, S.; Pontier, S.; Percherancier, Y.; Audet, M.; Paris, H.; Bouvier, M. Probing the Activation-Promoted Structural Rearrangements in Preassembled Receptor-G Protein Complexes. Nat. Struct. Mol. Biol., 2006, 13, 778-786.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 778-786
-
-
Gales, C.1
Van Durm, J.J.J.2
Schaak, S.3
Pontier, S.4
Percherancier, Y.5
Audet, M.6
Paris, H.7
Bouvier, M.8
-
117
-
-
78149286159
-
Molecular Organization and Dynamics of the Melatonin MT_ receptor/RGS20/G(i) Protein Complex Reveal Asymmetry of Receptor Dimers for RGS and G(i) Coupling
-
Maurice, P.; Daulat, A. M.; Turecek, R.; Ivankova-Susankova, K.; Zamponi, F.; Kamal, M.; Clement, N.; Guillaume, J.-L.; Bettler, B.; Gales, C.; et al. Molecular Organization and Dynamics of the Melatonin MT_ receptor/RGS20/G(i) Protein Complex Reveal Asymmetry of Receptor Dimers for RGS and G(i) Coupling. EMBO J., 2010, 29, 3646-3659.
-
(2010)
EMBO J
, vol.29
, pp. 3646-3659
-
-
Maurice, P.1
Daulat, A.M.2
Turecek, R.3
Ivankova-Susankova, K.4
Zamponi, F.5
Kamal, M.6
Clement, N.7
Guillaume, J.-L.8
Bettler, B.9
Gales, C.10
-
118
-
-
80054763193
-
Real-Time BRET Assays to Measure G Protein/effector Interactions
-
Petrin, D.; Robitaille, M.; Hebert, T. E. Real-Time BRET Assays to Measure G Protein/effector Interactions.Methods Mol. Biol. Clifton N.J., 2011, 756, 245-261.
-
(2011)
Methods Mol. Biol. Clifton N.J
, vol.756
, pp. 245-261
-
-
Petrin, D.1
Robitaille, M.2
Hebert, T.E.3
-
119
-
-
0027375964
-
Molecular Mechanisms of Membrane Receptor Desensitization
-
Lohse, M. J. Molecular Mechanisms of Membrane Receptor Desensitization.Biochim.Biophys. Acta, 1993, 1179, 171-188.
-
(1993)
Biochim.Biophys. Acta
, vol.1179
, pp. 171-188
-
-
Lohse, M.J.1
-
120
-
-
80052359992
-
Emerging Paradigms of B-Arrestin-Dependent Seven Transmembrane Receptor Signaling
-
Shukla, A. K.; Xiao, K.; Lefkowitz, R. J. Emerging Paradigms of B-Arrestin-Dependent Seven Transmembrane Receptor Signaling. Trends Biochem. Sci., 2011, 36, 457-469.
-
(2011)
Trends Biochem. Sci
, vol.36
, pp. 457-469
-
-
Shukla, A.K.1
Xiao, K.2
Lefkowitz, R.J.3
-
121
-
-
2342587513
-
Real-Time Detection of Interactions between the Human Oxytocin Receptor and G Protein-Coupled Receptor Kinase-2
-
Hasbi, A.; Devost, D.; Laporte, S. A.; Zingg, H. H. Real-Time Detection of Interactions between the Human Oxytocin Receptor and G Protein-Coupled Receptor Kinase-2. Mol. Endocrinol. Baltim. Md., 2004, 18, 1277-1286.
-
(2004)
Mol. Endocrinol. Baltim. Md
, vol.18
, pp. 1277-1286
-
-
Hasbi, A.1
Devost, D.2
Laporte, S.A.3
Zingg, H.H.4
-
122
-
-
34250714898
-
Oxyntomodulin Differentially Affects Glucagon-like Peptide-1 Receptor Beta-Arrestin Recruitment and Signaling through Galpha(s)
-
Jorgensen, R.; Kubale, V.; Vrecl, M.; Schwartz, T. W.; Elling, C. E. Oxyntomodulin Differentially Affects Glucagon-like Peptide-1 Receptor Beta-Arrestin Recruitment and Signaling through Galpha(s). J. Pharmacol. Exp. Ther., 2007, 322, 148-154.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.322
, pp. 148-154
-
-
Jorgensen, R.1
Kubale, V.2
Vrecl, M.3
Schwartz, T.W.4
Elling, C.E.5
-
123
-
-
38549084354
-
Characterization of G-Protein Coupled Receptor Kinase Interaction with the Neurokinin-1 Receptor Using Bioluminescence Resonance Energy Transfer
-
Jorgensen, R.; Holliday, N. D.; Hansen, J. L.; Vrecl, M.; Heding, A.; Schwartz, T. W.; Elling, C. E. Characterization of G-Protein Coupled Receptor Kinase Interaction with the Neurokinin-1 Receptor Using Bioluminescence Resonance Energy Transfer. Mol. Pharmacol. 2008, 73, 349-358.
-
(2008)
Mol. Pharmacol
, vol.73
, pp. 349-358
-
-
Jorgensen, R.1
Holliday, N.D.2
Hansen, J.L.3
Vrecl, M.4
Heding, A.5
Schwartz, T.W.6
Elling, C.E.7
-
124
-
-
0034595860
-
Differential Affinities of Visual Arrestin, Beta arrestin1, and Beta arrestin2 for G Protein-Coupled Receptors Delineate Two Major Classes of Receptors
-
Oakley, R. H.; Laporte, S. A.; Holt, J. A.; Caron, M. G.; Barak, L. S. Differential Affinities of Visual Arrestin, Beta arrestin1, and Beta arrestin2 for G Protein-Coupled Receptors Delineate Two Major Classes of Receptors. J. Biol. Chem. 2000, 275, 17201-17210.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 17201-17210
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
Caron, M.G.4
Barak, L.S.5
-
125
-
-
67650364823
-
Detection of GPCR/beta-Arrestin Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer Technology
-
Kocan, M.; Pfleger, K. D. G. Detection of GPCR/beta-Arrestin Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer Technology. Methods Mol. Biol. Clifton NJ 2009, 552, 305-317.
-
(2009)
Methods Mol. Biol. Clifton NJ
, vol.552
, pp. 305-317
-
-
Kocan, M.1
Pfleger, K.D.G.2
-
126
-
-
0033003760
-
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
-
Zhang, J. H.; Chung, T. D.; Oldenburg, K. R. A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J. Biomol. Screen. 1999, 4, 67-73.
-
(1999)
J. Biomol. Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
127
-
-
78649859393
-
Identification of Novel Species-Selective Agonists of the G-Protein-Coupled Receptor GPR35 That Promote Recruitment of B-Arrestin-2 and Activate Ga13
-
Jenkins, L.; Brea, J.; Smith, N. J.; Hudson, B. D.; Reilly, G.; Bryant, N. J.; Castro, M.; Loza, M.-I.; Milligan, G. Identification of Novel Species-Selective Agonists of the G-Protein-Coupled Receptor GPR35 That Promote Recruitment of B-Arrestin-2 and Activate Ga13. Biochem. J. 2010, 432, 451-459.
-
(2010)
Biochem. J
, vol.432
, pp. 451-459
-
-
Jenkins, L.1
Brea, J.2
Smith, N.J.3
Hudson, B.D.4
Reilly, G.5
Bryant, N.J.6
Castro, M.7
Loza, M.-I.8
Milligan, G.9
-
129
-
-
0036973242
-
The BRET2/arrestin Assay in Stable Recombinant Cells: A Platform to Screen for Compounds That Interact with G Protein-Coupled Receptors (GPCRS)
-
Bertrand, L.; Parent, S.; Caron, M.; Legault, M.; Joly, E.; Angers, S.; Bouvier, M.; Brown, M.; Houle, B.; Menard, L. The BRET2/arrestin Assay in Stable Recombinant Cells: A Platform to Screen for Compounds That Interact with G Protein-Coupled Receptors (GPCRS). J. Recept. Signal Transduct. Res. 2002, 22, 533-541.
-
(2002)
J. Recept. Signal Transduct. Res
, vol.22
, pp. 533-541
-
-
Bertrand, L.1
Parent, S.2
Caron, M.3
Legault, M.4
Joly, E.5
Angers, S.6
Bouvier, M.7
Brown, M.8
Houle, B.9
Menard, L.10
-
130
-
-
84876494666
-
A Simple Method to Generate Stable Cell Lines for the Analysis of Transient Protein-Protein Interactions
-
Savage, E. E.; Wootten, D.; Christopoulos, A.; Sexton, P. M.; Furness, S. G. B. A Simple Method to Generate Stable Cell Lines for the Analysis of Transient Protein-Protein Interactions. BioTechniques 2013, 54, 217-221.
-
(2013)
BioTechniques
, vol.54
, pp. 217-221
-
-
Savage, E.E.1
Wootten, D.2
Christopoulos, A.3
Sexton, P.M.4
Furness, S.G.B.5
-
131
-
-
77955799768
-
Protein-Protein Interactions Monitored in Cells from Transgenic Mice Using Bioluminescence Resonance Energy Transfer
-
Audet, M.; Lagace, M.; Silversides, D. W.; Bouvier, M. Protein-Protein Interactions Monitored in Cells from Transgenic Mice Using Bioluminescence Resonance Energy Transfer. FASEB J. 2010, 24, 2829-2838.
-
(2010)
FASEB J
, vol.24
, pp. 2829-2838
-
-
Audet, M.1
Lagace, M.2
Silversides, D.W.3
Bouvier, M.4
-
132
-
-
84885926147
-
Bioluminescence Resonance Energy Transfer Methods to Study G Protein-Coupled Receptor-Receptor Tyrosine Kinase Heteroreceptor Complexes
-
Borroto-Escuela, D. O.; Flajolet, M.; Agnati, L. F.; Greengard, P.; Fuxe, K. Bioluminescence Resonance Energy Transfer Methods to Study G Protein-Coupled Receptor-Receptor Tyrosine Kinase Heteroreceptor Complexes. Methods Cell Biol. 2013, 117, 141-164.
-
(2013)
Methods Cell Biol
, vol.117
, pp. 141-164
-
-
Borroto-Escuela, D.O.1
Flajolet, M.2
Agnati, L.F.3
Greengard, P.4
Fuxe, K.5
-
133
-
-
84873040275
-
G Protein-Coupled Receptor Heterodimerization in the Brain
-
Borroto-Escuela, D. O.; Romero-Fernandez, W.; Garriga, P.; Ciruela, F.; Narvaez, M.; Tarakanov, A. O.; Palkovits, M.; Agnati, L. F.; Fuxe, K. G Protein-Coupled Receptor Heterodimerization in the Brain. Methods Enzymol. 2013, 521, 281-294.
-
(2013)
Methods Enzymol
, vol.521
, pp. 281-294
-
-
Borroto-Escuela, D.O.1
Romero-Fernandez, W.2
Garriga, P.3
Ciruela, F.4
Narvaez, M.5
Tarakanov, A.O.6
Palkovits, M.7
Agnati, L.F.8
Fuxe, K.9
-
134
-
-
56749150875
-
FGF Acts as a Co-Transmitter through Adenosine A(2A) Receptor to Regulate Synaptic Plasticity
-
Flajolet, M.; Wang, Z.; Futter, M.; Shen, W.; Nuangchamnong, N.; Bendor, J.; Wallach, I.; Nairn, A. C.; Surmeier, D. J.; Greengard, P. FGF Acts as a Co-Transmitter through Adenosine A(2A) Receptor to Regulate Synaptic Plasticity. Nat. Neurosci. 2008, 11, 1402-1409.
-
(2008)
Nat. Neurosci
, vol.11
, pp. 1402-1409
-
-
Flajolet, M.1
Wang, Z.2
Futter, M.3
Shen, W.4
Nuangchamnong, N.5
Bendor, J.6
Wallach, I.7
Nairn, A.C.8
Surmeier, D.J.9
Greengard, P.10
-
135
-
-
82755177856
-
Fibroblast Growth Factor Receptor 1-5-Hydroxytryptamine 1A Heteroreceptor Complexes and Their Enhancement of Hippocampal Plasticity
-
Borroto-Escuela, D. O.; Romero-Fernandez, W.; Mudo, G.; Perez-Alea, M.; Ciruela, F.; Tarakanov, A. O.; Narvaez, M.; Liberto, V. Di; Agnati, L. F.; Belluardo, N.; et al. Fibroblast Growth Factor Receptor 1-5-Hydroxytryptamine 1A Heteroreceptor Complexes and Their Enhancement of Hippocampal Plasticity. Biol. Psychiatry 2012, 71, 84-91.
-
(2012)
Biol. Psychiatry
, vol.71
, pp. 84-91
-
-
Borroto-Escuela, D.O.1
Romero-Fernandez, W.2
Mudo, G.3
Perez-Alea, M.4
Ciruela, F.5
Tarakanov, A.O.6
Narvaez, M.7
Di Liberto, V.8
Agnati, L.F.9
Belluardo, N.10
-
136
-
-
84867234267
-
Sensitive and High Resolution Localization and Tracking of Membrane Proteins in Live Cells with BRET
-
Lan, T.-H.; Liu, Q.; Li, C.; Wu, G.; Lambert, N. A. Sensitive and High Resolution Localization and Tracking of Membrane Proteins in Live Cells with BRET. Traffic Cph. Den. 2012, 13, 1450-1456.
-
(2012)
Traffic Cph. Den
, vol.13
, pp. 1450-1456
-
-
Lan, T.-H.1
Liu, Q.2
Li, C.3
Wu, G.4
Lambert, N.A.5
-
137
-
-
0036091925
-
Ras Signalling on the Endoplasmic Reticulum and the Golgi
-
Chiu, V. K.; Bivona, T.; Hach, A.; Sajous, J. B.; Silletti, J.; Wiener, H.; Johnson, R. L. 2nd; Cox, A. D.; Philips, M. R. Ras Signalling on the Endoplasmic Reticulum and the Golgi. Nat Cell Biol. 2002, 4, 343-350.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 343-350
-
-
Chiu, V.K.1
Bivona, T.2
Hach, A.3
Sajous, J.B.4
Silletti, J.5
Wiener, H.6
Johnson II, R.L.7
Cox, A.D.8
Philips, M.R.9
-
138
-
-
84875246715
-
Identification of a Novel Prenyl and Palmitoyl Modification at the CaaX Motif of Cdc42 that Regulates RhoGDI Binding
-
Nishimura A1, Linder ME. Identification of a Novel Prenyl and Palmitoyl Modification at the CaaX Motif of Cdc42 that Regulates RhoGDI Binding. Mol. Cell Biol. 2013, 33, 1417-1429.
-
(2013)
Mol. Cell Biol
, vol.33
, pp. 1417-1429
-
-
Nishimura, A.1
Linder, M.E.2
-
139
-
-
0038729670
-
Measurement of the Millisecond Activation Switch of G Protein-Coupled Receptors in Living Cells. Nat
-
Vilardaga, J.-P.; Bunemann, M.; Krasel, C.; Castro, M.; Lohse, M. J. Measurement of the Millisecond Activation Switch of G Protein-Coupled Receptors in Living Cells. Nat. Biotechnol. 2003, 21, 807-812.
-
(2003)
Biotechnol
, vol.21
, pp. 807-812
-
-
Vilardaga, J.-P.1
Bunemann, M.2
Krasel, C.3
Castro, M.4
Lohse, M.J.5
-
140
-
-
27644521278
-
Turn-on Switch in Parathyroid Hormone Receptor by a Two-Step Parathyroid Hormone Binding Mechanism
-
Castro, M.; Nikolaev, V. O.; Palm, D.; Lohse, M. J.; Vilardaga, J.-P.Turn-on Switch in Parathyroid Hormone Receptor by a Two-Step Parathyroid Hormone Binding Mechanism. Proc. Natl. Acad. Sci. U. S. A. 2005, 102, 16084-16089.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 16084-16089
-
-
Castro, M.1
Nikolaev, V.O.2
Palm, D.3
Lohse, M.J.4
Vilardaga, J.-P.5
-
141
-
-
70349309325
-
Sustained Cyclic AMP Production by Parathyroid Hormone Receptor Endocytosis
-
Ferrandon, S.; Feinstein, T. N.; Castro, M.; Wang, B.; Bouley, R.; Potts, J. T.; Gardella, T. J.; Vilardaga, J.-P. Sustained Cyclic AMP Production by Parathyroid Hormone Receptor Endocytosis. Nat. Chem. Biol. 2009, 5, 734-742.
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 734-742
-
-
Ferrandon, S.1
Feinstein, T.N.2
Castro, M.3
Wang, B.4
Bouley, R.5
Potts, J.T.6
Gardella, T.J.7
Vilardaga, J.-P.8
-
142
-
-
84864117586
-
Allosteric Interactions within the ATB Angiotensin Receptor Homodimer: Role of the Conserved DRY Motif
-
Szalai, B.; Barkai, L.; Turu, G.; Szidonya, L.; Varnai, P.; Hunyady, L. Allosteric Interactions within the ATB Angiotensin Receptor Homodimer: Role of the Conserved DRY Motif. Biochem. Pharmacol. 2012, 84, 477-485.
-
(2012)
Biochem. Pharmacol
, vol.84
, pp. 477-485
-
-
Szalai, B.1
Barkai, L.2
Turu, G.3
Szidonya, L.4
Varnai, P.5
Hunyady, L.6
-
143
-
-
80053124471
-
Greatly Enhanced Detection of a Volatile Ligand at Femtomolar Levels Using Bioluminescence Resonance Energy Transfer (BRET)
-
Dacres, H.; Wang, J.; Leitch, V.; Horne, I.; Anderson, A. R.; Trowell, S. C. Greatly Enhanced Detection of a Volatile Ligand at Femtomolar Levels Using Bioluminescence Resonance Energy Transfer (BRET). Biosens. Bioelectron. 2011, 29, 119-124.
-
(2011)
Biosens. Bioelectron
, vol.29
, pp. 119-124
-
-
Dacres, H.1
Wang, J.2
Leitch, V.3
Horne, I.4
Anderson, A.R.5
Trowell, S.C.6
-
144
-
-
34249861932
-
Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine 1-phosphate/G13 Pathway
-
Jiang, L. I.; Collins, J.; Davis, R.; Lin, K.-M.; DeCamp, D.; Roach, T.; Hsueh, R.; Rebres, R. A.; Ross, E. M.; Taussig, R.; Fraser, I.: Sternweis, P. C. Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine 1-phosphate/G13 Pathway. J. Biol. Chem. 2007, 282, 10576-10584.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 10576-10584
-
-
Jiang, L.I.1
Collins, J.2
Davis, R.3
Lin, K.-M.4
Decamp, D.5
Roach, T.6
Hsueh, R.7
Rebres, R.A.8
Ross, E.M.9
Taussig, R.10
Fraser, I.11
Sternweis, P.C.12
-
145
-
-
50449102062
-
Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP Biosensor
-
Barak, L. S.; Salahpour, A.; Zhang, X.; Masri, B.; Sotnikova, T. D.; Ramsey, A. J.; Violin, J. D.; Lefkowitz, R. J.; Caron, M. G.; Gainetdinov, R. R. Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP Biosensor. Mol. Pharmacol. 2008, 74, 585-594.
-
(2008)
Mol. Pharmacol
, vol.74
, pp. 585-594
-
-
Barak, L.S.1
Salahpour, A.2
Zhang, X.3
Masri, B.4
Sotnikova, T.D.5
Ramsey, A.J.6
Violin, J.D.7
Lefkowitz, R.J.8
Caron, M.G.9
Gainetdinov, R.R.10
-
146
-
-
17644391412
-
Monitoring Agonist-Promoted Conformational Changes of Beta-Arrestin in Living Cells by Intramolecular BRET
-
Charest, P. G.; Terrillon, S.; Bouvier, M. Monitoring Agonist-Promoted Conformational Changes of Beta-Arrestin in Living Cells by Intramolecular BRET. EMBO Rep. 2005, 6, 334-340.
-
(2005)
EMBO Rep
, vol.6
, pp. 334-340
-
-
Charest, P.G.1
Terrillon, S.2
Bouvier, M.3
-
147
-
-
48249126790
-
Distinct Conformational Changes in Beta-Arrestin Report Biased Agonism at Seven-Transmembrane Receptors
-
Shukla, A. K.; Violin, J. D.; Whalen, E. J.; Gesty-Palmer, D.; Shenoy, S. K.; Lefkowitz, R. J. Distinct Conformational Changes in Beta-Arrestin Report Biased Agonism at Seven-Transmembrane Receptors. Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 9988-9993.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A
, vol.105
, pp. 9988-9993
-
-
Shukla, A.K.1
Violin, J.D.2
Whalen, E.J.3
Gesty-Palmer, D.4
Shenoy, S.K.5
Lefkowitz, R.J.6
|