Heterotropic cooperativity within and between protomers of an oligomeric M2 muscarinic receptor

Biochemistry

Volumn 51, Issue 22, 2012, Pages 4518-4540

  Shivnaraine, Rabindra V ^a   Huang, Xi Ping ^b,c   Seidenberg, Margaret ^b   Ellis, John ^b   Wells, James W ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC SITE; CHO CELL; COOPERATIVITY; DOSE-DEPENDENT; HETEROTROPIC COOPERATIVITY; HILL COEFFICIENT; MUSCARINIC RECEPTOR; PROTOMERS; RADIOLIGANDS; RATE OF DISSOCIATION; TETRAMERS;

DISSOCIATION; SERPENTINE;

OLIGOMERS;

BENZILIC ACID DERIVATIVE; GALLAMINE; METHYLSCOPOLAMINE; MUSCARINIC M2 RECEPTOR; QUINUCLIDINYLBENZILATE; SERPENTINE; TETRAMER; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HETEROTROPHY; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANIMALS; CHO CELLS; CHOLINERGIC ANTAGONISTS; CRICETINAE; GALLAMINE TRIETHIODIDE; KINETICS; MUSCARINIC ANTAGONISTS; N-METHYLSCOPOLAMINE; PROTEIN SUBUNITS; QUINUCLIDINYL BENZILATE; RECEPTOR, MUSCARINIC M2; SF9 CELLS; SOLUBILITY; SWINE;

SUS;

EID: 84861854597     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3000287     Document Type: Article

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