Structure of class B GPCR corticotropin-releasing factor receptor 1

Nature

Volumn 499, Issue 7459, 2013, Pages 438-443

  Hollenstein, Kaspar ^a   Kean, James ^a   Bortolato, Andrea ^a   Cheng, Robert K Y ^a   Doré, Andrew S ^a   Jazayeri, Ali ^a   Cooke, Robert M ^a   Weir, Malcolm ^a   Marshall, Fiona H ^a  

^a Heptares Therapeutics Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; DOPAMINE 3 RECEPTOR; G PROTEIN COUPLED RECEPTOR;

AMINO ACID; CRYSTAL STRUCTURE; DRUG DEVELOPMENT; MEMBRANE; METABOLISM; MOLECULAR ANALYSIS; NEUROLOGY; PEPTIDE; POLYMERASE CHAIN REACTION; PROTEIN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN DISEASE; BRAIN METABOLISM; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; HUMAN; HYDROGEN BOND; LIGAND BINDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; STRESS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINOPYRIDINES; BINDING SITES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RECEPTORS, DOPAMINE D3;

EID: 84881173408     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12357     Document Type: Article

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