Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 44, 2005, Pages 16084-16089

  Castro, Marián ^a,c   Nikolaev, Viacheslav O ^a   Palm, Dieter ^b   Lohse, Martin J ^a   Vilardaga, Jean Pierre ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

FRET; G protein coupled receptor; Ligand receptor interaction; Real time binding; Time resolved signaling

Indexed keywords

CYAN FLUORESCENT PROTEIN; G PROTEIN COUPLED RECEPTOR; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE[1-34]; YELLOW FLUORESCENT PROTEIN;

ARTICLE; BINDING SITE; CALCIUM HOMEOSTASIS; CONFORMATIONAL TRANSITION; DRUG RECEPTOR BINDING; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE SWITCHING; HORMONE BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; SECOND MESSENGER; SENSOR;

EID: 27644521278     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0503942102     Document Type: Article

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